Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

Journal of Experimental Medicine

Volumn 207, Issue 11, 2010, Pages 2331-2341

  Grainger, John R ^a,c   Smith, Katie A ^a   Hewitson, James P ^a   McSorley, Henry J ^a   Harcus, Yvonne ^a   Filbey, Kara J ^a   Finney, Constance A M ^a,e   Greenwood, Edward J D ^a,f   Knox, David P ^b   Wilson, Mark S ^c,g   Belkaid, Yasmine ^c   Rudensky, Alexander Y ^d   Maizels, Rick M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^g NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ANTIGEN; INTERLEUKIN 6; INTERLEUKIN 7; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GENE INDUCTION; HELIGMOSOMOIDES POLYGYRUS; HELMINTHIASIS; IMMUNITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REGULATORY T LYMPHOCYTE; RESPIRATORY TRACT INFLAMMATION;

ANIMALS; ANTIGENS, HELMINTH; BENZAMIDES; CELL PROLIFERATION; CHRONIC DISEASE; DIOXOLES; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HOST-PARASITE INTERACTIONS; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; NEMATOSPIROIDES DUBIUS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; STRONGYLIDA INFECTIONS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH2 CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 78149261083     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20101074     Document Type: Article

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