Modeling of ligand binding to G protein coupled receptors: Cannabinoid CB 1, CB 2 and adrenergic β 2AR

Journal of Molecular Modeling

Volumn 17, Issue 9, 2011, Pages 2353-2366

  Latek, Dorota ^a,d   Kolinski, Michal ^b   Ghoshdastider, Umesh ^a,c   Debinski, Aleksander ^a   Bombolewski, Rafal ^a   Plazinska, Anita ^b   Jozwiak, Krzysztof ^b   Filipek, Slawomir ^a  

^a UNIVERSITY OF WARSAW   (Poland)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^c GOETHE UNIVERSITY   (Germany)

^d INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

Author keywords

Cannabinoid receptors; Docking; Fenoterol; GPCRs; Molecular dynamics; Molecular switches

Indexed keywords

5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; ANISOLE; BETA 2 ADRENERGIC RECEPTOR; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CARBOXYL GROUP; FENOTEROL; HYDROXYL GROUP; MORPHOLINE; PHENYLALANINE; SERINE;

BINDING KINETICS; BINDING SITE; CONFERENCE PAPER; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTON TRANSPORT; STEREOISOMERISM;

AMINO ACID MOTIFS; ARACHIDONIC ACIDS; BINDING SITES; FENOTEROL; HUMANS; HYDROGEN BONDING; INDOLES; LIGANDS; MOLECULAR DYNAMICS SIMULATION; PIPERIDINES; POLYUNSATURATED ALKAMIDES; PYRAZOLES; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; RECEPTORS, ADRENERGIC, BETA-2; STEREOISOMERISM; TETRAHYDROCANNABINOL; THERMODYNAMICS;

EID: 80255139280     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-011-0986-7     Document Type: Conference Paper

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