The effects of charge-neutralizing mutation D6.30N on the functions of CB1 and CB2 cannabinoid receptors

FEBS Letters

Volumn 580, Issue 22, 2006, Pages 5392-5398

  Nebane, Ntsang M ^a   Kellie, Brandon ^a   Song, Zhao Hui ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Cannabinoid; Constitutive activity; G protein coupled receptor; Ionic lock; Mutagenesis; Salt bridge

Indexed keywords

AMINO ACID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR; CYCLIC AMP; FORSKOLIN; SODIUM CHLORIDE;

AMINO ACID SEQUENCE; ARTICLE; CELL STRAIN HEK293; EMBRYO; EPITHELIUM CELL; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID SUBSTITUTION; CELL LINE; CYCLIC AMP; FORSKOLIN; HUMANS; LIGANDS; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2;

EID: 33748803064     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.09.001     Document Type: Article

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