The difference between the CB1 and CB2 cannabinoid receptors at position 5.46 is crucial for the selectivity of WIN55212-2 for CB2

Molecular Pharmacology

Volumn 56, Issue 4, 1999, Pages 834-840

  Song, Z H ^a,b   Slowey, Carole Anne ^b   Hurst, Dow P ^c   Reggio, Patricia H ^c  

^a University of Louisville School of Medicine   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c KENNESAW STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ANANDAMIDE; CANNABINOID RECEPTOR; DEXANABINOL; RECEPTOR SUBTYPE;

ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; HUMANS; HYDROCARBONS, AROMATIC; INDOLES; MODELS, MOLECULAR; MORPHOLINES; MUTAGENESIS, SITE-DIRECTED; NAPHTHALENES; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032860406     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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