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Volumn 278, Issue 23, 2011, Pages 4649-4667

Gram-positive bacterial superantigen outside-in signaling causes toxic shock syndrome

Author keywords

MRSA; mucosal immunity; Staphylococcus aureus; Streptococcus pyogenes; superantigen; toxic shock syndrome

Indexed keywords

BACTERIAL ANTIGEN; CYTOLYSIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STAPHYLOCOCCUS ANTIGEN; STREPTOCOCCUS ANTIGEN; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 80054860481     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08151.x     Document Type: Review
Times cited : (86)

References (164)
  • 2
    • 0032551901 scopus 로고    scopus 로고
    • Staphylococcus aureus infections
    • Lowy FD, (1998) Staphylococcus aureus infections. N Engl J Med 339, 520-532.
    • (1998) N Engl J Med , vol.339 , pp. 520-532
    • Lowy, F.D.1
  • 3
    • 73149124063 scopus 로고    scopus 로고
    • Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis
    • Schlievert PM, Strandberg KL, Lin YC, Peterson ML, &, Leung DY, (2010) Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis. J Allergy Clin Immunol 125, 39-49.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 39-49
    • Schlievert, P.M.1    Strandberg, K.L.2    Lin, Y.C.3    Peterson, M.L.4    Leung, D.Y.5
  • 4
    • 70349647066 scopus 로고    scopus 로고
    • Staphylococcal and streptococcal superantigens: An update
    • In (Kotb M.A. & Fraser J.D. eds), ASM Press, Washington, DC.
    • Schlievert PM, &, Bohach GA, (2007) Staphylococcal and streptococcal superantigens: an update. In Superantigens: Molecular Basis for Their Role in Human Diseases (, Kotb MA, &, Fraser JD, eds), pp. 21-36. ASM Press, Washington, DC.
    • (2007) Superantigens: Molecular Basis for Their Role in Human Diseases , pp. 21-36
    • Schlievert, P.M.1    Bohach, G.A.2
  • 5
    • 0027960065 scopus 로고
    • MSCRAMM-mediated adherence of microorganisms to host tissues
    • Patti JM, Allen BL, McGavin MJ, &, Hook M, (1994) MSCRAMM-mediated adherence of microorganisms to host tissues. Annu Rev Microbiol 48, 585-617.
    • (1994) Annu Rev Microbiol , vol.48 , pp. 585-617
    • Patti, J.M.1    Allen, B.L.2    McGavin, M.J.3    Hook, M.4
  • 6
    • 0025044872 scopus 로고
    • Staphylococcal and streptococcal pyrogenic toxins involved in toxic shock syndrome and related illnesses
    • Bohach GA, Fast DJ, Nelson RD, &, Schlievert PM, (1990) Staphylococcal and streptococcal pyrogenic toxins involved in toxic shock syndrome and related illnesses. Crit Rev Microbiol 17, 251-272. (Pubitemid 20249880)
    • (1990) Critical Reviews in Microbiology , vol.17 , Issue.4 , pp. 251-272
    • Bohach, G.A.1    Fast, D.J.2    Nelson, R.D.3    Schlievert, P.M.4
  • 9
    • 0034780632 scopus 로고    scopus 로고
    • Toxic shock syndrome and bacterial superantigens: An update
    • DOI 10.1146/annurev.micro.55.1.77
    • McCormick JK, Yarwood JM, &, Schlievert PM, (2001) Toxic shock syndrome and bacterial superantigens: an update. Annu Rev Microbiol 55, 77-104. (Pubitemid 32978101)
    • (2001) Annual Review of Microbiology , vol.55 , pp. 77-104
    • McCormick, J.K.1    Yarwood, J.M.2    Schlievert, P.M.3
  • 10
    • 0030830116 scopus 로고    scopus 로고
    • Mitogenic factors from group G streptococci associated with scarlet fever and streptococcal toxic shock syndrome
    • Assimacopoulos AP, Stoehr JA, &, Schlievert PM, (1997) Mitogenic factors from group G streptococci associated with scarlet fever and streptococcal toxic shock syndrome. Adv Exp Med Biol 418, 109-114. (Pubitemid 27438389)
    • (1997) Advances in Experimental Medicine and Biology , vol.418 , pp. 109-114
    • Assimacopoulos, A.P.1    Stoehr, J.A.2    Schlievert, P.M.3
  • 11
    • 78651084774 scopus 로고    scopus 로고
    • Complete genome sequencing and analysis of a Lancefield group G Streptococcus dysgalactiae subsp. equisimilis strain causing streptococcal toxic shock syndrome (STSS)
    • Shimomura Y, Okumura K, Murayama SY, Yagi J, Ubukata K, Kirikae T, &, Miyoshi-Akiyama T, (2011) Complete genome sequencing and analysis of a Lancefield group G Streptococcus dysgalactiae subsp. equisimilis strain causing streptococcal toxic shock syndrome (STSS). BMC Genomics 12, 17.
    • (2011) BMC Genomics , vol.12 , pp. 17
    • Shimomura, Y.1    Okumura, K.2    Murayama, S.Y.3    Yagi, J.4    Ubukata, K.5    Kirikae, T.6    Miyoshi-Akiyama, T.7
  • 14
    • 52949126938 scopus 로고    scopus 로고
    • Characterization of toxin production of coagulase-negative staphylococci isolated from food and starter cultures
    • Zell C, Resch M, Rosenstein R, Albrecht T, Hertel C, &, Gotz F, (2008) Characterization of toxin production of coagulase-negative staphylococci isolated from food and starter cultures. Int J Food Microbiol 127, 246-251.
    • (2008) Int J Food Microbiol , vol.127 , pp. 246-251
    • Zell, C.1    Resch, M.2    Rosenstein, R.3    Albrecht, T.4    Hertel, C.5    Gotz, F.6
  • 17
    • 0035006360 scopus 로고    scopus 로고
    • Structural features of a zinc binding site in the superantigen streptococcal pyrogenic exotoxin A (SpeA1): Implications for MHC class II recognition
    • DOI 10.1110/ps.330101
    • Baker M, Gutman DM, Papageorgiou AC, Collins CM, &, Acharya KR, (2001) Structural features of a zinc binding site in the superantigen strepococcal pyrogenic exotoxin A (SpeA1): implications for MHC class II recognition. Protein Sci 10, 1268-1273. (Pubitemid 32476489)
    • (2001) Protein Science , vol.10 , Issue.6 , pp. 1268-1273
    • Baker, M.1    Gutman, D.M.2    Papageorgiou, A.C.3    Collins, C.M.4    Acharya, K.R.5
  • 19
    • 0033521685 scopus 로고    scopus 로고
    • Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors
    • DOI 10.1093/emboj/18.1.9
    • Papageorgiou AC, Collins CM, Gutman DM, Kline JB, O'Brien SM, Tranter HS, &, Acharya KR, (1999) Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors. EMBO J 18, 9-21. (Pubitemid 29005018)
    • (1999) EMBO Journal , vol.18 , Issue.1 , pp. 9-21
    • Papageorgiou, A.C.1    Collins, C.M.2    Gutman, D.M.3    Kline, J.B.4    O'Brien, S.M.5    Tranter, H.S.6    Acharya, K.R.7
  • 21
    • 78650074574 scopus 로고    scopus 로고
    • The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation
    • Saline M, Rodstrom KE, Fischer G, Orekhov VY, Karlsson BG, &, Lindkvist-Petersson K, (2010) The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation. Nat Commun 1, 119.
    • (2010) Nat Commun , vol.1 , pp. 119
    • Saline, M.1    Rodstrom, K.E.2    Fischer, G.3    Orekhov, V.Y.4    Karlsson, B.G.5    Lindkvist-Petersson, K.6
  • 25
  • 26
    • 0019328405 scopus 로고
    • Toxic-shock syndrome: Epidemiologic features, recurrence, risk factors, and prevention
    • Davis JP, Chesney PJ, Wand PJ, &, LaVenture M, (1980) Toxic-shock syndrome: epidemiologic features, recurrence, risk factors, and prevention. N Engl J Med 303, 1429-1435.
    • (1980) N Engl J Med , vol.303 , pp. 1429-1435
    • Davis, J.P.1    Chesney, P.J.2    Wand, P.J.3    Laventure, M.4
  • 28
    • 0018070935 scopus 로고
    • Toxic-shock syndrome associated with phage-group-I Staphylococci
    • Todd JK, Kapral FA, Fishaut M, &, Welch TR, (1978) Toxic shock syndrome associated with phage group 1 staphylococci. Lancet 2, 1116-1118. (Pubitemid 9060056)
    • (1978) Lancet , vol.2 , Issue.8100 , pp. 1116-1118
    • Todd, J.1    Fishaut, M.2    Kapral, F.3    Welch, T.4
  • 29
    • 0019980277 scopus 로고
    • Nonmenstrual toxic shock syndrome. A review of 130 cases
    • 6 II
    • Reingold AL, Hargrett NT, Dan BB, Shands KN, Strickland BY, &, Broome CV, (1982) Nonmenstrual toxic shock syndrome: a review of 130 cases. Ann Intern Med 96, 871-874. (Pubitemid 12088886)
    • (1982) Annals of Internal Medicine , vol.96 , pp. 871-874
    • Reingold, A.L.1    Hargrett, N.T.2    Dan, B.B.3
  • 32
    • 0020664177 scopus 로고
    • Production of staphylococcal pyrogenic exotoxin type C: Influence of physical and chemical factors
    • Schlievert PM, &, Blomster DA, (1983) Production of staphylococcal pyrogenic exotoxin type C: influence of physical and chemical factors. J Infect Dis 147, 236-242. (Pubitemid 13195102)
    • (1983) Journal of Infectious Diseases , vol.147 , Issue.2 , pp. 236-242
    • Schlievert, P.M.1    Blomster, D.A.2
  • 33
    • 0034016779 scopus 로고    scopus 로고
    • Oxygen and carbon dioxide regulation of toxic shock syndrome toxin 1 production by Staphylococcus aureus MN8
    • Yarwood JM, &, Schlievert PM, (2000) Oxygen and carbon dioxide regulation of toxic shock syndrome toxin 1 production by Staphylococcus aureus MN8. J Clin Microbiol 38, 1797-1803. (Pubitemid 30253918)
    • (2000) Journal of Clinical Microbiology , vol.38 , Issue.5 , pp. 1797-1803
    • Yarwood, J.M.1    Schlievert, P.M.2
  • 34
    • 2942625813 scopus 로고    scopus 로고
    • Reemergence of Staphylococcal toxic shock syndrome in Minneapolis-St. Paul, Minnesota, during the 2000-2003 surveillance period
    • DOI 10.1128/JCM.42.6.2875-2876.2004
    • Schlievert PM, Tripp TJ, &, Peterson ML, (2004) Reemergence of staphylococcal toxic shock syndrome in Minneapolis-St. Paul, Minnesota, during the 2000-2003 surveillance period. J Clin Microbiol 42, 2875-2876. (Pubitemid 38747565)
    • (2004) Journal of Clinical Microbiology , vol.42 , Issue.6 , pp. 2875-2876
    • Schlievert, P.M.1    Tripp, T.J.2    Peterson, M.L.3
  • 35
    • 0032810029 scopus 로고    scopus 로고
    • Involvement of enterotoxins G and I in staphylococcal toxic shock syndrome and staphylococcal scarlet fever
    • Jarraud S, Cozon G, Vandenesch F, Bes M, Etienne J, &, Lina G, (1999) Involvement of enterotoxins G and I in staphylococcal toxic shock syndrome and staphylococcal scarlet fever. J Clin Microbiol 37, 2446-2449. (Pubitemid 29337259)
    • (1999) Journal of Clinical Microbiology , vol.37 , Issue.8 , pp. 2446-2449
    • Jarraud, S.1    Cozon, G.2    Vandenesch, F.3    Bes, M.4    Etienne, J.5    Lina, G.6
  • 36
    • 84948010525 scopus 로고
    • Toxic shock syndrome: A newly recognized complication of influenza and influenzalike illness
    • DOI 10.1001/jama.257.8.1053
    • MacDonald KL, Osterholm MT, Hedberg CW, Schrock CG, Peterson GF, Jentzen JM, Leonard SA, &, Schlievert PM, (1987) Toxic shock syndrome. A newly recognized complication of influenza and influenzalike illness. JAMA 257, 1053-1058. (Pubitemid 17031493)
    • (1987) Journal of the American Medical Association , vol.257 , Issue.8 , pp. 1053-1058
    • MacDonald, K.L.1    Osterholm, M.T.2    Hedberg, C.W.3
  • 37
    • 79955676178 scopus 로고    scopus 로고
    • Coagulase-positive staphylococcal necrotizing fasciitis subsequent to shoulder sprain in a healthy woman
    • Kim HJ, Kim DH, &, Ko DH, (2010) Coagulase-positive staphylococcal necrotizing fasciitis subsequent to shoulder sprain in a healthy woman. Clin Orthop Surg 2, 256-259.
    • (2010) Clin Orthop Surg , vol.2 , pp. 256-259
    • Kim, H.J.1    Kim, D.H.2    Ko, D.H.3
  • 38
    • 79952063317 scopus 로고    scopus 로고
    • Community-acquired methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a healthy adolescent male
    • Lalich IJ, &, Sam-Agudu NA, (2010) Community-acquired methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a healthy adolescent male. Minn Med 93, 44-46.
    • (2010) Minn Med , vol.93 , pp. 44-46
    • Lalich, I.J.1    Sam-Agudu, N.A.2
  • 40
    • 81555216444 scopus 로고    scopus 로고
    • Staphylococcal and streptococcal toxic shock and Kawasaki syndromes
    • In (Schlossberg D. Ed.), Cambridge University Press, New York, NY.
    • Assimacopoulos A, &, Schlievert PM, (2008) Staphylococcal and streptococcal toxic shock and Kawasaki syndromes. In Clinical Infectious Disease (, Schlossberg D, Ed.), pp. 129-134. Cambridge University Press, New York, NY.
    • (2008) Clinical Infectious Disease , pp. 129-134
    • Assimacopoulos, A.1    Schlievert, P.M.2
  • 43
  • 44
    • 34250622434 scopus 로고    scopus 로고
    • Toxic shock-like syndrome associated with staphylococcal enterocolitis in an HIV-infected man
    • Kotler DP, Sandkovsky U, Schlievert PM, &, Sordillo EM, (2007) Toxic shock-like syndrome associated with staphylococcal enterocolitis in an HIV-infected man. Clin Infect Dis 44, e121-e123.
    • (2007) Clin Infect Dis , vol.44
    • Kotler, D.P.1    Sandkovsky, U.2    Schlievert, P.M.3    Sordillo, E.M.4
  • 45
    • 0034101969 scopus 로고    scopus 로고
    • Application of staphylococcal enterotoxin B on normal and atopic skin induces up-regulation of T cells by a superantigen-mediated mechanism
    • Skov L, Olsen JV, Giorno R, Schlievert PM, Baadsgaard O, &, Leung DY, (2000) Application of staphylococcal enterotoxin B on normal and atopic skin induces up-regulation of T cells by a superantigen-mediated mechanism. J Allergy Clin Immunol 105, 820-826. (Pubitemid 30226459)
    • (2000) Journal of Allergy and Clinical Immunology , vol.105 , Issue.4 , pp. 820-826
    • Skov, L.1    Olsen, J.V.2    Giorno, R.3    Schlievert, P.M.4    Baadsgaard, O.5    Leung, D.Y.M.6
  • 46
    • 72049120384 scopus 로고    scopus 로고
    • Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity
    • John CC, Niermann M, Sharon B, Peterson ML, Kranz DM, &, Schlievert PM, (2009) Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity. Clin Infect Dis 49, 1893-1896.
    • (2009) Clin Infect Dis , vol.49 , pp. 1893-1896
    • John, C.C.1    Niermann, M.2    Sharon, B.3    Peterson, M.L.4    Kranz, D.M.5    Schlievert, P.M.6
  • 47
    • 77950244130 scopus 로고
    • Studies in scarlet fever II. Studies on the use of convalescent scarlet fever serum and Dochez' scarlatinal antistreptococcic serum for the treatment of scarlet fever
    • Birkhaug KE, (1925) Studies in scarlet fever II. Studies on the use of convalescent scarlet fever serum and Dochez' scarlatinal antistreptococcic serum for the treatment of scarlet fever. Bull Johns Hopkins Hosp 36, 134-171.
    • (1925) Bull Johns Hopkins Hosp , vol.36 , pp. 134-171
    • Birkhaug, K.E.1
  • 48
    • 0023219580 scopus 로고
    • Clinical and bacteriologic observations of a toxic shock-like syndrome due to streptococcus pyogenes
    • Cone LA, Woodard DR, Schlievert PM, &, Tomory GS, (1987) Clinical and bacteriologic observations of a toxic shock-like syndrome due to Streptococcus pyogenes. N Engl J Med 317, 146-149. (Pubitemid 17092152)
    • (1987) New England Journal of Medicine , vol.317 , Issue.3 , pp. 146-149
    • Cone, L.A.1    Woodard, D.R.2    Schlievert, P.M.3    Tomory, G.S.4
  • 50
    • 0018539572 scopus 로고
    • Reinterpretation of the Dick test: Role of group A streptococcal pyrogenic exotoxin
    • Schlievert PM, Bettin KM, &, Watson DW, (1979) Reinterpretation of the Dick test: role of group A streptococcal pyrogenic exotoxin. Infect Immun 26, 467-472.
    • (1979) Infect Immun , vol.26 , pp. 467-472
    • Schlievert, P.M.1    Bettin, K.M.2    Watson, D.W.3
  • 53
    • 0030037566 scopus 로고    scopus 로고
    • Severe invasive group A streptococcal disease: Clinical description and mechanisms of pathogenesis
    • Schlievert PM, Assimacopoulos AP, &, Cleary PP, (1996) Severe invasive group A streptococcal disease: clinical description and mechanisms of pathogenesis. J Lab Clin Med 127, 13-22.
    • (1996) J Lab Clin Med , vol.127 , pp. 13-22
    • Schlievert, P.M.1    Assimacopoulos, A.P.2    Cleary, P.P.3
  • 54
    • 0025894808 scopus 로고
    • Molecular analysis of pyrogenic exotoxins from Streptococcus pyogenes isolates associated with toxic shock-like syndrome
    • Hauser AR, Stevens DL, Kaplan EL, &, Schlievert PM, (1991) Molecular analysis of pyrogenic exotoxins from Streptococcus pyogenes isolates associated with toxic shock-like syndrome. J Clin Microbiol 29, 1562-1567.
    • (1991) J Clin Microbiol , vol.29 , pp. 1562-1567
    • Hauser, A.R.1    Stevens, D.L.2    Kaplan, E.L.3    Schlievert, P.M.4
  • 55
    • 0024309617 scopus 로고
    • Quantification and toxicity of group A streptococcal pyrogenic exotoxins in an animal model of toxic shock syndrome-like illness
    • Lee PK, &, Schlievert PM, (1989) Quantification and toxicity of group A streptococcal pyrogenic exotoxins in an animal model of toxic shock syndrome-like illness. J Clin Microbiol 27, 1890-1892. (Pubitemid 19182902)
    • (1989) Journal of Clinical Microbiology , vol.27 , Issue.8 , pp. 1890-1892
    • Lee, P.K.1    Schlievert, P.M.2
  • 56
    • 0024307720 scopus 로고
    • Bacteriophage association of streptococcal pyrogenic exotoxin type C
    • Goshorn SC, &, Schlievert PM, (1989) Bacteriophage association of streptococcal pyrogenic exotoxin type C. J Bacteriol 171, 3068-3073. (Pubitemid 19145654)
    • (1989) Journal of Bacteriology , vol.171 , Issue.6 , pp. 3068-3073
    • Goshorn, S.C.1    Schlievert, P.M.2
  • 58
    • 0020084666 scopus 로고
    • Tri-state toxic-shock syndrome study. I. Epidemiologic findings
    • Osterholm MT, Davis JP, Gibson RW, Mandel JS, Wintermeyer LA, Helms CM, Forfang JC, Rondeau J, &, Vergeront JM, (1982) Tri-state toxic-state syndrome study. I. Epidemiologic findings. J Infect Dis 145, 431-440. (Pubitemid 12158327)
    • (1982) Journal of Infectious Diseases , vol.145 , Issue.4 , pp. 431-440
    • Osterholm, M.T.1    Davis, J.P.2    Gibson, R.W.3
  • 59
    • 0021325455 scopus 로고
    • Clindamycin-induced suppression of toxic-shock syndrome-associated exotoxin production
    • Schlievert PM, &, Kelly JA, (1984) Clindamycin-induced suppression of toxic-shock syndrome-associated exotoxin production. J Infect Dis 149, 471. (Pubitemid 14138254)
    • (1984) Journal of Infectious Diseases , vol.149 , Issue.3 , pp. 471
    • Schlievert, P.M.1    Kelly, J.A.2
  • 60
    • 33845285901 scopus 로고    scopus 로고
    • An early favorable outcome of streptococcal toxic shock syndrome may require a combination of antimicrobial and intravenous gamma globulin therapy together with activated protein C
    • DOI 10.1080/00365540500373224, PII X573481G08236776
    • Cone LA, Stone RA, Schlievert PM, Sneider RA, Rubin AM, Jesser K, &, Renker SW, (2006) An early favorable outcome of streptococcal toxic shock syndrome may require a combination of antimicrobial and intravenous gamma globulin therapy together with activated protein C. Scand J Infect Dis 38, 960-963. (Pubitemid 44869264)
    • (2006) Scandinavian Journal of Infectious Diseases , vol.38 , Issue.11-12 , pp. 960-963
    • Cone, L.A.1    Stone, R.A.2    Schlievert, P.M.3    Sneider, R.A.4    Rubin, A.M.5    Jesser, K.6    Renker, S.W.7
  • 63
    • 0018688944 scopus 로고
    • Production of pyrogenic exotoxin by groups of streptococci: Association with group A
    • Schlievert PM, Bettin KM, &, Watson DW, (1979) Production of pyrogenic exotoxin by groups of streptococci: association with group A. J Infect Dis 140, 676-681. (Pubitemid 10214190)
    • (1979) Journal of Infectious Diseases , vol.140 , Issue.5 , pp. 676-681
    • Schlievert, P.M.1    Bettin, K.M.2    Watson, D.W.3
  • 66
    • 72849134568 scopus 로고    scopus 로고
    • Reduction in Staphylococcus aureus growth and exotoxin production and in vaginal interleukin 8 levels due to glycerol monolaurate in tampons
    • Strandberg KL, Peterson ML, Schaefers MM, Case LC, Pack MC, Chase DJ, &, Schlievert PM, (2009) Reduction in Staphylococcus aureus growth and exotoxin production and in vaginal interleukin 8 levels due to glycerol monolaurate in tampons. Clin Infect Dis 49, 1711-1717.
    • (2009) Clin Infect Dis , vol.49 , pp. 1711-1717
    • Strandberg, K.L.1    Peterson, M.L.2    Schaefers, M.M.3    Case, L.C.4    Pack, M.C.5    Chase, D.J.6    Schlievert, P.M.7
  • 67
    • 0019983061 scopus 로고
    • Toxin and enzyme characterization of Staphylococcus aureus isolates from patients with and without toxic shock syndrome
    • 6 II
    • Schlievert PM, Osterholm MT, Kelly JA, &, Nishimura RD, (1982) Toxin and enzyme characterization of Staphylococcus aureus isolates from patients with and without toxic shock syndrome. Ann Intern Med 96, 937-940. (Pubitemid 12088904)
    • (1982) Annals of Internal Medicine , vol.96 , pp. 937-940
    • Schlievert, P.M.1    Osterholm, M.T.2    Kelly, J.A.3    Nishimura, R.D.4
  • 69
    • 0033787718 scopus 로고    scopus 로고
    • Epithelial cell layer thickness and immune cell populations in the normal human vagina at different stages of the menstrual cycle
    • Patton DL, Thwin SS, Meier A, Hooton TM, Stapleton AE, &, Eschenbach DA, (2000) Epithelial cell layer thickness and immune cell populations in the normal human vagina at different stages of the menstrual cycle. Am J Obstet Gynecol 183, 967-973.
    • (2000) Am J Obstet Gynecol , vol.183 , pp. 967-973
    • Patton, D.L.1    Thwin, S.S.2    Meier, A.3    Hooton, T.M.4    Stapleton, A.E.5    Eschenbach, D.A.6
  • 71
    • 0031891166 scopus 로고    scopus 로고
    • The physical, chemical and functional properties of lipids in the skin and other biological barriers
    • DOI 10.1016/S0009-3084(97)00108-4, PII S0009308497001084
    • Wertz PW, &, van den Bergh B, (1998) The physical, chemical and functional properties of lipids in the skin and other biological barriers. Chem Phys Lipids 91, 85-96. (Pubitemid 28142956)
    • (1998) Chemistry and Physics of Lipids , vol.91 , Issue.2 , pp. 85-96
    • Wertz, P.W.1    Van Den Bergh, B.2
  • 72
    • 0035184191 scopus 로고    scopus 로고
    • A comparative light-microscopic, electron-microscopic and chemical study of human vaginal and buccal epithelium
    • DOI 10.1016/S0003-9969(01)00082-6, PII S0003996901000826
    • Thompson IO, van der Bijl P, van Wyk CW, &, van Eyk AD, (2001) A comparative light-microscopic, electron-microscopic and chemical study of human vaginal and buccal epithelium. Arch Oral Biol 46, 1091-1098. (Pubitemid 33086338)
    • (2001) Archives of Oral Biology , vol.46 , Issue.12 , pp. 1091-1098
    • Thompson, I.O.C.1    Van Der Bijl, P.2    Van Wyk, C.W.3    Van Eyk, A.D.4
  • 74
    • 16244381104 scopus 로고    scopus 로고
    • The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1
    • DOI 10.1128/IAI.73.4.2164-2174.2005
    • Peterson ML, Ault K, Kremer MJ, Klingelhutz AJ, Davis CC, Squier CA, &, Schlievert PM, (2005) The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1. Infect Immun 73, 2164-2174. (Pubitemid 40470816)
    • (2005) Infection and Immunity , vol.73 , Issue.4 , pp. 2164-2174
    • Peterson, M.L.1    Ault, K.2    Kremer, M.J.3    Klingelhutz, A.J.4    Davis, C.C.5    Squier, C.A.6    Schlievert, P.M.7
  • 76
    • 84920308956 scopus 로고
    • The serological differentiation of pathogenic and non-pathogenic strains of hemolytic streptococci from parturient women
    • Lancefield RC, &, Hare R, (1935) The serological differentiation of pathogenic and non-pathogenic strains of hemolytic streptococci from parturient women. J Exp Med 61, 335-349.
    • (1935) J Exp Med , vol.61 , pp. 335-349
    • Lancefield, R.C.1    Hare, R.2
  • 77
    • 33748290188 scopus 로고    scopus 로고
    • Two cases of group A streptococcal vulvovaginitis in premenopausal adults in a sexual health setting
    • DOI 10.1071/SH05062
    • Bray S, &, Morgan J, (2006) Two cases of group A streptococcal vulvovaginitis in premenopausal adults in a sexual health setting. Sex Health 3, 187-188. (Pubitemid 44325579)
    • (2006) Sexual Health , vol.3 , Issue.3 , pp. 187-188
    • Bray, S.1    Morgan, J.2
  • 78
    • 34548488961 scopus 로고    scopus 로고
    • Streptococcus pyogenes Pharyngeal Colonization Resulting in Recurrent, Prepubertal Vulvovaginitis
    • DOI 10.1016/j.jpag.2006.12.001, PII S1083318806003469
    • Hansen MT, Sanchez VT, Eyster K, &, Hansen KA, (2007) Streptococcus pyogenes pharyngeal colonization resulting in recurrent, prepubertal vulvovaginitis. J Pediatr Adolesc Gynecol 20, 315-317. (Pubitemid 47375133)
    • (2007) Journal of Pediatric and Adolescent Gynecology , vol.20 , Issue.5 , pp. 315-317
    • Hansen, M.T.1    Sanchez, V.T.2    Eyster, K.3    Hansen, K.A.4
  • 79
    • 7944239243 scopus 로고
    • Acute vulvovaginitis in streptococcal infections
    • Hedlund P, (1953) Acute vulvovaginitis in streptococcal infections. Nord Med 49, 566-568.
    • (1953) Nord Med , vol.49 , pp. 566-568
    • Hedlund, P.1
  • 80
    • 0014481650 scopus 로고
    • Vulvovaginitis in the premenarcheal child
    • Heller RH, Joseph JM, &, Davis HJ, (1969) Vulvovaginitis in the premenarcheal child. J Pediatr 74, 370-377.
    • (1969) J Pediatr , vol.74 , pp. 370-377
    • Heller, R.H.1    Joseph, J.M.2    Davis, H.J.3
  • 81
    • 43249104781 scopus 로고    scopus 로고
    • Lactational amenorrhea as a risk factor for group a streptococcal vaginitis
    • DOI 10.1086/587748
    • Meltzer MC, &, Schwebke JR, (2008) Lactational amenorrhea as a risk factor for group a streptococcal vaginitis. Clin Infect Dis 46, e112-e115. (Pubitemid 351706757)
    • (2008) Clinical Infectious Diseases , vol.46 , Issue.10
    • Meltzer, M.C.1    Schwebke, J.R.2
  • 82
    • 0022313153 scopus 로고
    • Group A β-hemolytic streptococcal vulvovaginitis: A recurring problem
    • O'Connor PA, &, Oliver WJ, (1985) Group A beta-hemolytic streptococcal vulvovaginitis: a recurring problem. Pediatr Emerg Care 1, 94-95. (Pubitemid 16141145)
    • (1985) Pediatric Emergency Care , vol.1 , Issue.2 , pp. 94-95
    • O'Connor, P.A.1    Oliver, W.J.2
  • 83
    • 0020287375 scopus 로고
    • Vulvovaginitis in prepubertal girls: The importance of group A Streptococcus
    • Schwartz RH, Wientzen RL, &, Barsanti RG, (1982) Vulvovaginitis in prepubertal girls: the importance of group A Streptococcus. South Med J 75, 446-447. (Pubitemid 12010400)
    • (1982) Southern Medical Journal , vol.75 , Issue.4 , pp. 446-447
    • Schwartz, R.H.1    Wientzen, R.L.2    Barsanti, R.G.3
  • 84
    • 33947532066 scopus 로고    scopus 로고
    • Recurrent group A streptococcal vulvovaginitis in adult women: Family epidemiology
    • Sobel JD, Funaro D, &, Kaplan EL, (2007) Recurrent group A streptococcal vulvovaginitis in adult women: family epidemiology. Clin Infect Dis 44, e43-e45.
    • (2007) Clin Infect Dis , vol.44
    • Sobel, J.D.1    Funaro, D.2    Kaplan, E.L.3
  • 85
    • 0021160536 scopus 로고
    • Study of staphylococcal toxic shock syndrome toxin in human epithelial cell culture
    • Kushnaryov VM, Bergdoll MS, MacDonald HS, Vellinga J, &, Reiser R, (1984) Study of staphylococcal toxic shock syndrome toxin in human epithelial cell culture. J Infect Dis 150, 535-545. (Pubitemid 14013974)
    • (1984) Journal of Infectious Diseases , vol.150 , Issue.4 , pp. 535-545
    • Kushnaryov, V.M.1    Bergdoll, M.S.2    MacDonald, H.S.3
  • 86
    • 0021276128 scopus 로고
    • Staphylococcal toxic shock toxin specifically binds to cultured human epithelial cells and is rapidly internalized
    • Kushnaryov VM, MacDonald HS, Reiser R, &, Bergdoll MS, (1984) Staphylococcal toxic shock toxin specifically binds to cultured human epithelial cells and is rapidly internalized. Infect Immun 45, 566-571. (Pubitemid 14066166)
    • (1984) Infection and Immunity , vol.45 , Issue.3 , pp. 566-571
    • Kushnaryov, V.M.1    McDonald, H.S.2    Reiser, R.3    Bergdoll, M.S.4
  • 87
    • 0033985109 scopus 로고    scopus 로고
    • Induction of tumor necrosis factor alpha and interleukin-8 gene expression in bronchial epithelial cells by toxic shock syndrome toxin 1
    • Aubert V, Schneeberger D, Sauty A, Winter J, Sperisen P, Aubert JD, &, Spertini F, (2000) Induction of tumor necrosis factor alpha and interleukin-8 gene expression in bronchial epithelial cells by toxic shock syndrome toxin 1. Infect Immun 68, 120-124. (Pubitemid 30016686)
    • (2000) Infection and Immunity , vol.68 , Issue.1 , pp. 120-124
    • Aubert, V.1    Schneeberger, D.2    Sauty, A.3    Winter, J.4    Sperisen, P.5    Aubert, J.-D.6    Spertini, F.7
  • 88
    • 70149112044 scopus 로고    scopus 로고
    • Proinflammatory impact of Staphylococcus aureus enterotoxin B on human nasal epithelial cells and inhibition by dexamethasone
    • Yu RL, &, Dong Z, (2009) Proinflammatory impact of Staphylococcus aureus enterotoxin B on human nasal epithelial cells and inhibition by dexamethasone. Am J Rhinol Allergy 23, 15-20.
    • (2009) Am J Rhinol Allergy , vol.23 , pp. 15-20
    • Yu, R.L.1    Dong, Z.2
  • 89
    • 31944451254 scopus 로고    scopus 로고
    • Proinflammatory effects of Staphylococcus aureus exotoxin B on nasal epithelial cells
    • DOI 10.1016/j.otohns.2005.11.016, PII S0194599805021364
    • Damm M, Quante G, Rosenbohm J, &, Rieckmann R, (2006) Proinflammatory effects of Staphylococcus aureus exotoxin B on nasal epithelial cells. Otolaryngol Head Neck Surg 134, 245-249. (Pubitemid 43187124)
    • (2006) Otolaryngology - Head and Neck Surgery , vol.134 , Issue.2 , pp. 245-249
    • Damm, M.1    Quante, G.2    Rosenbohm, J.3    Rieckmann, R.4
  • 90
    • 33749250410 scopus 로고    scopus 로고
    • Staphylococcus aureus enterotoxins induce IL-8 secretion by human nasal epithelial cells
    • O'Brien GJ, Riddell G, Elborn JS, Ennis M, &, Skibinski G, (2006) Staphylococcus aureus enterotoxins induce IL-8 secretion by human nasal epithelial cells. Respir Res 7, 115.
    • (2006) Respir Res , vol.7 , pp. 115
    • O'Brien, G.J.1    Riddell, G.2    Elborn, J.S.3    Ennis, M.4    Skibinski, G.5
  • 91
    • 0030789791 scopus 로고    scopus 로고
    • Modulation of cytokine production from an EpiOcular corneal cell culture model in response to Staphylococcus aureus superantigen
    • Thakur A, Clegg A, Chauhan A, &, Willcox MD, (1997) Modulation of cytokine production from an EpiOcular corneal cell culture model in response to Staphylococcus aureus superantigen. Aust N Z J Ophthalmol 25 (Suppl 1), S43-S45. (Pubitemid 27337280)
    • (1997) Australian and New Zealand Journal of Ophthalmology , vol.25 , Issue.SUPPL. 1
    • Thakur, A.1    Clegg, A.2    Chauhan, A.3    Willcox, M.D.P.4
  • 92
    • 0345222473 scopus 로고    scopus 로고
    • Airway exposure to bacterial superantigen (SEB) induces lymphocyte-dependent airway inflammation associated with increased airway responsiveness - A model for non-allergic asthma
    • Herz U, Ruckert R, Wollenhaupt K, Tschernig T, Neuhaus-Steinmetz U, Pabst R, &, Renz H, (1999) Airway exposure to bacterial superantigen (SEB) induces lymphocyte-dependent airway inflammation associated with increased airway responsiveness - a model for non-allergic asthma. Eur J Immunol 29, 1021-1031. (Pubitemid 29119083)
    • (1999) European Journal of Immunology , vol.29 , Issue.3 , pp. 1021-1031
    • Herz, U.1    Ruckert, R.2    Wollenhaupt, K.3    Tschernig, T.4    Neuhaus-Steinmetz, U.5    Pabst, R.6    Renz, H.7
  • 93
    • 31844432403 scopus 로고    scopus 로고
    • Intranasal exposure to bacterial superantigens induces airway inflammation in HLA class II transgenic mice
    • DOI 10.1128/IAI.74.2.1284-1296.2006
    • Rajagopalan G, Iijima K, Singh M, Kita H, Patel R, &, David CS, (2006) Intranasal exposure to bacterial superantigens induces airway inflammation in HLA class II transgenic mice. Infect Immun 74, 1284-1296. (Pubitemid 43185568)
    • (2006) Infection and Immunity , vol.74 , Issue.2 , pp. 1284-1296
    • Rajagopalan, G.1    Iijima, K.2    Singh, M.3    Kita, H.4    Patel, R.5    David, C.S.6
  • 95
    • 0030732635 scopus 로고    scopus 로고
    • Detection of interleukin-6 and interleukin-2 in serum of rhesus monkeys exposed to a nonlethal dose of Staphylococcal enterotoxin B
    • Krakauer T, Pitt L, &, Hunt RE, (1997) Detection of interleukin-6 and interleukin-2 in serum of rhesus monkeys exposed to a nonlethal dose of staphylococcal enterotoxin B. Mil Med 162, 612-615. (Pubitemid 27494608)
    • (1997) Military Medicine , vol.162 , Issue.9 , pp. 612-615
    • Krakauer, T.1    Pitt, L.2    Hunt, R.E.3
  • 97
    • 33749267789 scopus 로고    scopus 로고
    • Acute systemic immune activation following conjunctival exposure to staphylococcal enterotoxin B
    • DOI 10.1128/IAI.00671-06
    • Rajagopalan G, Smart MK, Patel R, &, David CS, (2006) Acute systemic immune activation following conjunctival exposure to staphylococcal enterotoxin B. Infect Immun 74, 6016-6019. (Pubitemid 44484590)
    • (2006) Infection and Immunity , vol.74 , Issue.10 , pp. 6016-6019
    • Rajagopalan, G.1    Smart, M.K.2    Patel, R.3    David, C.S.4
  • 98
    • 0020081376 scopus 로고
    • Enhancement of host susceptibility to lethal endotoxin shock by staphylococcal pyrogenic exotoxin type C
    • Schlievert PM, (1982) Enhancement of host susceptibility to lethal endotoxin shock by staphylococcal pyrogenic exotoxin type C. Infect Immun 36, 123-128. (Pubitemid 12156414)
    • (1982) Infection and Immunity , vol.36 , Issue.1 , pp. 123-128
    • Schlievert, P.M.1
  • 99
    • 0014753260 scopus 로고
    • A purified group A streptococcal pyrogenic exotoxin. Physiochemical and biological properties including the enhancement of susceptibility to endotoxin lethal shock
    • Kim YB, &, Watson DW, (1970) A purified group A streptococcal pyrogenic exotoxin. Physiochemical and biological properties including the enhancement of susceptibility to endotoxin lethal shock. J Exp Med 131, 611-622.
    • (1970) J Exp Med , vol.131 , pp. 611-622
    • Kim, Y.B.1    Watson, D.W.2
  • 100
    • 33846537280 scopus 로고    scopus 로고
    • Acute systemic immune activation following vaginal exposure to staphylococcal enterotoxin B-Implications for menstrual shock
    • DOI 10.1016/j.jri.2006.06.007, PII S0165037806000982
    • Rajagopalan G, Smart MK, Murali N, Patel R, &, David CS, (2007) Acute systemic immune activation following vaginal exposure to staphylococcal enterotoxin B-implications for menstrual shock. J Reprod Immunol 73, 51-59. (Pubitemid 46161831)
    • (2007) Journal of Reproductive Immunology , vol.73 , Issue.1 , pp. 51-59
    • Rajagopalan, G.1    Smart, M.K.2    Murali, N.3    Patel, R.4    David, C.S.5
  • 101
    • 0032403547 scopus 로고    scopus 로고
    • Oral administration of the bacterial superantigen staphylococcal enterotoxin B induces activation and cytokine production by T cells in murine gut-associated lymphoid tissue
    • Spiekermann GM, &, Nagler-Anderson C, (1998) Oral administration of the bacterial superantigen staphylococcal enterotoxin B induces activation and cytokine production by T cells in murine gut-associated lymphoid tissue. J Immunol 161, 5825-5831. (Pubitemid 28535947)
    • (1998) Journal of Immunology , vol.161 , Issue.11 , pp. 5825-5831
    • Spiekermann, G.M.1    Nagler-Anderson, C.2
  • 102
    • 0027321840 scopus 로고
    • Localization of an immunologically functional region of the streptococcal superantigen pepsin-extracted fragment of type 5 M protein
    • Wang B, Schlievert PM, Gaber AO, &, Kotb M, (1993) Localization of an immunologically functional region of the streptococcal superantigen pepsin-extracted fragment of type 5 M protein. J Immunol 151, 1419-1429. (Pubitemid 23219279)
    • (1993) Journal of Immunology , vol.151 , Issue.3 , pp. 1419-1429
    • Wang, B.1    Schlievert, P.M.2    Gaber, A.O.3    Kotb, M.4
  • 104
    • 0028093030 scopus 로고
    • Identification of staphylococcal enterotoxin B sequences important for induction of lymphocyte proliferation by using synthetic peptide fragments of the toxin
    • Jett M, Neill R, Welch C, Boyle T, Bernton E, Hoover D, Lowell G, Hunt RE, Chatterjee S, &, Gemski P, (1994) Identification of staphylococcal enterotoxin B sequences important for induction of lymphocyte proliferation by using synthetic peptide fragments of the toxin. Infect Immun 62, 3408-3415. (Pubitemid 24232127)
    • (1994) Infection and Immunity , vol.62 , Issue.8 , pp. 3408-3415
    • Jett, M.1    Neill, R.2    Welch, C.3    Boyle, T.4    Bernton, E.5    Hoover, D.6    Lowell, G.7    Hunt, R.E.8    Chatterjee, S.9    Gemski, P.10
  • 105
    • 0034030865 scopus 로고    scopus 로고
    • Superantigen antagonist protects against lethal shock and defines a new domain for T-cell activation
    • DOI 10.1038/74672
    • Arad G, Levy R, Hillman D, &, Kaempfer R, (2000) Superantigen antagonist protects against lethal shock and defines a new domain for T-cell activation. Nat Med 6, 414-421. (Pubitemid 30208158)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 414-421
    • Arad, G.1    Levy, R.2    Hillman, D.3    Kaempfer, R.4
  • 107
    • 1542362406 scopus 로고    scopus 로고
    • Broad-spectrum immunity against superantigens is elicited in mice protected from lethal shock by a superantigen antagonist peptide
    • DOI 10.1016/j.imlet.2003.11.003, PII S0165247803002566
    • Arad G, Hillman D, Levy R, &, Kaempfer R, (2004) Broad-spectrum immunity against superantigens is elicited in mice protected from lethal shock by a superantigen antagonist peptide. Immunol Lett 91, 141-145. (Pubitemid 38296371)
    • (2004) Immunology Letters , vol.91 , Issue.2-3 , pp. 141-145
    • Arad, G.1    Hillman, D.2    Levy, R.3    Kaempfer, R.4
  • 108
    • 0034978628 scopus 로고    scopus 로고
    • Superantigen antagonist blocks Th1 cytokine gene induction and lethal shock
    • Arad G, Hillman D, Levy R, &, Kaempfer R, (2001) Superantigen antagonist blocks Th1 cytokine gene induction and lethal shock. J Leukoc Biol 69, 921-927. (Pubitemid 32577893)
    • (2001) Journal of Leukocyte Biology , vol.69 , Issue.6 , pp. 921-927
    • Arad, G.1    Hillman, D.2    Levy, R.3    Kaempfer, R.4
  • 109
    • 7044286500 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of staphylococcal superantigen peptide antagonists
    • DOI 10.1128/IAI.72.11.6733-6737.2004
    • Rajagopalan G, Sen MM, &, David CS, (2004) In vitro and in vivo evaluation of staphylococcal superantigen peptide antagonists. Infect Immun 72, 6733-6737. (Pubitemid 39425463)
    • (2004) Infection and Immunity , vol.72 , Issue.11 , pp. 6733-6737
    • Rajagopalan, G.1    Sen, M.M.2    David, C.S.3
  • 110
    • 0036130701 scopus 로고    scopus 로고
    • Identification of a transcytosis epitope on staphylococcal enterotoxins
    • DOI 10.1128/IAI.70.4.2178-2186.2002
    • Shupp JW, Jett M, &, Pontzer CH, (2002) Identification of a transcytosis epitope on staphylococcal enterotoxins. Infect Immun 70, 2178-2186. (Pubitemid 34242221)
    • (2002) Infection and Immunity , vol.70 , Issue.4 , pp. 2178-2186
    • Shupp, J.W.1    Jett, M.2    Pontzer, C.H.3
  • 111
  • 114
  • 115
    • 33747961675 scopus 로고    scopus 로고
    • Comparisons of mouse and rabbit models of toxic shock syndrome
    • Dinges MM, Jessurun J, &, Schlievert PM, (1998) Comparisons of mouse and rabbit models of toxic shock syndrome. Int Congr Symp Ser 229, 167-168.
    • (1998) Int Congr Symp ser , vol.229 , pp. 167-168
    • Dinges, M.M.1    Jessurun, J.2    Schlievert, P.M.3
  • 116
    • 0034783461 scopus 로고    scopus 로고
    • Comparative analysis of lipopolysaccharide-induced tumor necrosis factor alpha activity in serum and lethality in mice and rabbits pretreated with the staphylococcal superantigen toxic shock syndrome toxin 1
    • DOI 10.1128/IAI.69.11.7169-7172.2001
    • Dinges MM, &, Schlievert PM, (2001) Comparative analysis of lipopolysaccharide-induced tumor necrosis factor alpha activity in serum and lethality in mice and rabbits pretreated with the staphylococcal superantigen toxic shock syndrome toxin 1. Infect Immun 69, 7169-7172. (Pubitemid 32995481)
    • (2001) Infection and Immunity , vol.69 , Issue.11 , pp. 7169-7172
    • Dinges, M.M.1    Schlievert, P.M.2
  • 117
    • 0018603816 scopus 로고
    • Biogenic amine involvement in pyrogenicity and enhancement of lethal endotoxin shock by group A streptococcal pyrogenic exotoxin
    • Schlievert PM, &, Watson DW, (1979) Biogenic amine involvement in pyrogenicity and enhancement of lethal endotoxin shock by group A streptococcal pyrogenic exotoxin. Proc Soc Exp Biol Med 162, 269-274. (Pubitemid 10200489)
    • (1979) Proceedings of the Society for Experimental Biology and Medicine , vol.162 , Issue.2 , pp. 269-274
    • Schlievert, P.M.1    Watson, D.W.2
  • 120
    • 0242288475 scopus 로고    scopus 로고
    • Association of human leukocyte antigen with outcomes of infectious diseases: The streptococcal experience
    • DOI 10.1080/00365540310015962
    • Kotb M, Norrby-Teglund A, McGeer A, Green K, &, Low DE, (2003) Association of human leukocyte antigen with outcomes of infectious diseases: the streptococcal experience. Scand J Infect Dis 35, 665-669. (Pubitemid 37336890)
    • (2003) Scandinavian Journal of Infectious Diseases , vol.35 , Issue.9 , pp. 665-669
    • Kotb, M.1    Norrby-Teglund, A.2    McGeer, A.3    Green, K.4    Low, D.E.5
  • 121
    • 0036737299 scopus 로고    scopus 로고
    • Differential presentation of group A streptococcal superantigens by HLA class II DQ and DR alleles
    • Norrby-Teglund A, Nepom GT, &, Kotb M, (2002) Differential presentation of group A streptococcal superantigens by HLA class II DQ and DR alleles. Eur J Immunol 32, 2570-2577.
    • (2002) Eur J Immunol , vol.32 , pp. 2570-2577
    • Norrby-Teglund, A.1    Nepom, G.T.2    Kotb, M.3
  • 122
    • 33847408274 scopus 로고    scopus 로고
    • HLA transgenic mice provide evidence for a direct and dominant role of HLA class II variation in modulating the severity of streptococcal sepsis
    • Nooh MM, El-Gengehi N, Kansal R, David CS, &, Kotb M, (2007) HLA transgenic mice provide evidence for a direct and dominant role of HLA class II variation in modulating the severity of streptococcal sepsis. J Immunol 178, 3076-3083. (Pubitemid 46333188)
    • (2007) Journal of Immunology , vol.178 , Issue.5 , pp. 3076-3083
    • Nooh, M.M.1    El-Gengehi, N.2    Kansal, R.3    David, C.S.4    Kotb, M.5
  • 123
    • 79952764512 scopus 로고    scopus 로고
    • Individual genetic variations directly effect polarization of cytokine responses to superantigens associated with streptococcal sepsis: Implications for customized patient care
    • Nooh MM, Nookala S, Kansal R, &, Kotb M, (2011) Individual genetic variations directly effect polarization of cytokine responses to superantigens associated with streptococcal sepsis: implications for customized patient care. J Immunol 186, 3156-3163.
    • (2011) J Immunol , vol.186 , pp. 3156-3163
    • Nooh, M.M.1    Nookala, S.2    Kansal, R.3    Kotb, M.4
  • 124
    • 0029153035 scopus 로고
    • Multiple binding sites for bacterial superantigens on soluble class II MHC molecules
    • Kozono H, Parker D, White J, Marrack P, &, Kappler J, (1995) Multiple binding sites for bacterial superantigens on soluble class II MHC molecules. Immunity 3, 187-196.
    • (1995) Immunity , vol.3 , pp. 187-196
    • Kozono, H.1    Parker, D.2    White, J.3    Marrack, P.4    Kappler, J.5
  • 125
    • 0033008083 scopus 로고    scopus 로고
    • The structural basis of T cell activation by superantigens
    • DOI 10.1146/annurev.immunol.17.1.435
    • Li H, Llera A, Malchiodi EL, &, Mariuzza RA, (1999) The structural basis of T cell activation by superantigens. Annu Rev Immunol 17, 435-466. (Pubitemid 29241131)
    • (1999) Annual Review of Immunology , vol.17 , pp. 435-466
    • Li, H.1    Llera, A.2    Malchiodi, E.L.3    Mariuzza, R.A.4
  • 126
    • 0028559548 scopus 로고
    • Toxic shock syndrome toxin-1 complexed with a class II major histocompatibility molecule HLA-DR1
    • Kim J, Urban RG, Strominger JL, &, Wiley DC, (1994) Toxic shock syndrome toxin-1 complexed with a class II major histocompatibility molecule HLA-DR1. Science 266, 1870-1874.
    • (1994) Science , vol.266 , pp. 1870-1874
    • Kim, J.1    Urban, R.G.2    Strominger, J.L.3    Wiley, D.C.4
  • 128
    • 0029963332 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-associated peptides control the presentation of bacterial superantigens to T cells
    • DOI 10.1084/jem.183.3.1083
    • Wen R, Cole GA, Surman S, Blackman MA, &, Woodland DL, (1996) Major histocompatibility complex class II-associated peptides control the presentation of bacterial superantigens to T cells. J Exp Med 183, 1083-1092. (Pubitemid 26113972)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.3 , pp. 1083-1092
    • Wen, R.1    Cole, G.A.2    Surman, S.3    Blackman, M.A.4    Woodland, D.L.5
  • 130
    • 0035129453 scopus 로고    scopus 로고
    • Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II
    • DOI 10.1016/S1074-7613(01)00092-9
    • Li Y, Li H, Dimasi N, McCormick JK, Martin R, Schuck P, Schlievert PM, &, Mariuzza RA, (2001) Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II. Immunity 14, 93-104. (Pubitemid 32144690)
    • (2001) Immunity , vol.14 , Issue.1 , pp. 93-104
    • Li, Y.1    Li, H.2    Dimasi, N.3    McCormick, J.K.4    Martin, R.5    Schuck, P.6    Schlievert, P.M.7    Mariuzza, R.A.8
  • 131
    • 0031556023 scopus 로고    scopus 로고
    • A structural and functional comparison of staphylococcal enterotoxins A and C2 reveals remarkable similarity and dissimilarity
    • DOI 10.1006/jmbi.1997.1023
    • Schad EM, Papageorgiou AC, Svensson LA, &, Acharya KR, (1997) A structural and functional comparison of staphylococcal enterotoxins A and C2 reveals remarkable similarity and dissimilarity. J Mol Biol 269, 270-280. (Pubitemid 27248290)
    • (1997) Journal of Molecular Biology , vol.269 , Issue.2 , pp. 270-280
    • Schad, E.M.1    Papageorgiou, A.C.2    Svensson, L.A.3    Acharya, K.R.4
  • 132
    • 0029730778 scopus 로고    scopus 로고
    • 2+ at 2.7 Å Resolution. Implications for major histocompatibility complex class II binding
    • DOI 10.1074/jbc.271.50.32212
    • Sundstrom M, Hallen D, Svensson A, Schad E, Dohlsten M, &, Abrahmsen L, (1996) The co-crystal structure of staphylococcal enterotoxin type A with Zn2+ at 2.7 A resolution. Implications for major histocompatibility complex class II binding. J Biol Chem 271, 32212-32216. (Pubitemid 26422256)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.50 , pp. 32212-32216
    • Sundstrom, M.1    Hallen, D.2    Svensson, A.3    Schad, E.4    Dohlsten, M.5    Abrahmsen, L.6
  • 133
    • 0029062894 scopus 로고
    • Characterization of two distinct MHC class II binding sites in the superantigen staphylococcal enterotoxin A
    • Abrahmsen L, Dohlsten M, Segren S, Bjork P, Jonsson E, &, Kalland T, (1995) Characterization of two distinct MHC class II binding sites in the superantigen staphylococcal enterotoxin A. EMBO J 14, 2978-2986.
    • (1995) EMBO J , vol.14 , pp. 2978-2986
    • Abrahmsen, L.1    Dohlsten, M.2    Segren, S.3    Bjork, P.4    Jonsson, E.5    Kalland, T.6
  • 134
    • 0029147099 scopus 로고
    • Staphylococcal enterotoxin A has two cooperative binding sites on major histocompatibility complex class II
    • Hudson KR, Tiedemann RE, Urban RG, Lowe SC, Strominger JL, &, Fraser JD, (1995) Staphylococcal enterotoxin A has two cooperative binding sites on major histocompatibility complex class II. J Exp Med 182, 711-720.
    • (1995) J Exp Med , vol.182 , pp. 711-720
    • Hudson, K.R.1    Tiedemann, R.E.2    Urban, R.G.3    Lowe, S.C.4    Strominger, J.L.5    Fraser, J.D.6
  • 135
    • 0030761504 scopus 로고    scopus 로고
    • The superantigen streptococcal pyrogenic exotoxin C (SPE-C) exhibits a novel mode of action
    • DOI 10.1084/jem.186.3.375
    • Li PL, Tiedemann RE, Moffat SL, &, Fraser JD, (1997) The superantigen streptococcal pyrogenic exotoxin C (SPE-C) exhibits a novel mode of action. J Exp Med 186, 375-383. (Pubitemid 27332895)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.3 , pp. 375-383
    • Li, P.-L.1    Tiedemann, R.E.2    Moffat, S.L.3    Fraser, J.D.4
  • 136
    • 0037369835 scopus 로고    scopus 로고
    • The zinc-dependent major histocompatibility complex class II binding site of streptococcal pyrogenic exotoxin C is critical for maximal superantigen function and toxic activity
    • DOI 10.1128/IAI.71.3.1548-1550.2003
    • Tripp TJ, McCormick JK, Webb JM, &, Schlievert PM, (2003) The zinc-dependent major histocompatibility complex class II binding site of streptococcal pyrogenic exotoxin C is critical for maximal superantigen function and toxic activity. Infect Immun 71, 1548-1550. (Pubitemid 36254343)
    • (2003) Infection and Immunity , vol.71 , Issue.3 , pp. 1548-1550
    • Tripp, T.J.1    McCormick, J.K.2    Webb, J.M.3    Schlievert, P.M.4
  • 137
    • 0030798632 scopus 로고    scopus 로고
    • Crystal structure of the streptococcal superantigen SPE-C: Dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules
    • DOI 10.1038/nsb0897-635
    • Roussel A, Anderson BF, Baker HM, Fraser JD, &, Baker EN, (1997) Crystal structure of the streptococcal superantigen SPE-C: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules. Nat Struct Biol 4, 635-643. (Pubitemid 27323446)
    • (1997) Nature Structural Biology , vol.4 , Issue.8 , pp. 635-643
    • Roussel, A.1    Anderson, B.F.2    Baker, H.M.3    Fraser, J.D.4    Baker, E.N.5
  • 138
    • 0033521608 scopus 로고    scopus 로고
    • Identification and characterization of novel superantigens from Streptococcus pyogenes
    • Proft T, Moffatt SL, Berkahn CJ, &, Fraser JD, (1999) Identification and characterization of novel superantigens from Streptococcus pyogenes. J Exp Med 189, 89-102.
    • (1999) J Exp Med , vol.189 , pp. 89-102
    • Proft, T.1    Moffatt, S.L.2    Berkahn, C.J.3    Fraser, J.D.4
  • 139
    • 34250333206 scopus 로고    scopus 로고
    • Toxins and superantigens of group A streptococci
    • In (Fishchetti V.A. Novick R.P. Ferretti J.J. Portnoy D.A. & Rood J.I. eds), ASM Press, Washington, DC.
    • McCormick JK, Peterson ML, &, Schlievert PM, (2006) Toxins and superantigens of group A streptococci. In Gram Positive Pathogens (, Fishchetti VA, Novick RP, Ferretti JJ, Portnoy DA, &, Rood JI, eds), pp. 47-58. ASM Press, Washington, DC.
    • (2006) Gram Positive Pathogens , pp. 47-58
    • McCormick, J.K.1    Peterson, M.L.2    Schlievert, P.M.3
  • 140
    • 37049178741 scopus 로고
    • The staphylococcal enterotoxins and their relatives
    • Marrack P, &, Kappler J, (1990) The staphylococcal enterotoxins and their relatives. Science 248, 1066.
    • (1990) Science , vol.248 , pp. 1066
    • Marrack, P.1    Kappler, J.2
  • 141
    • 0032412391 scopus 로고    scopus 로고
    • Three-dimensional structure of the complex between a T cell receptor β chain and the superantigen staphylococcal enterotoxin B
    • DOI 10.1016/S1074-7613(00)80646-9
    • Li H, Llera A, Tsuchiya D, Leder L, Ysern X, Schlievert PM, Karjalainen K, &, Mariuzza RA, (1998) Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B. Immunity 9, 807-816. (Pubitemid 29024460)
    • (1998) Immunity , vol.9 , Issue.6 , pp. 807-816
    • Hongmin, L.1    Llera, A.2    Tsuchiya, D.3    Leder, L.4    Ysern, X.5    Schlievert, P.M.6    Karjalainen, K.7    Mariuzza, R.A.8
  • 143
    • 0036091233 scopus 로고    scopus 로고
    • Structures of two streptococcal superantigens bound to TCR β chains reveal diversity in the architecture of T cell signaling complexes
    • DOI 10.1016/S0969-2126(02)00759-1, PII S0969212602007591
    • Sundberg EJ, Li H, Llera AS, McCormick JK, Tormo J, Schlievert PM, Karjalainen K, &, Mariuzza RA, (2002) Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes. Structure 10, 687-699. (Pubitemid 34520468)
    • (2002) Structure , vol.10 , Issue.5 , pp. 687-699
    • Sundberg, E.J.1    Li, H.2    Llera, A.S.3    McCormick, J.K.4    Tormo, J.5    Schlievert, P.M.6    Karjalainen, K.7    Mariuzza, R.A.8
  • 144
    • 0042346160 scopus 로고    scopus 로고
    • Functional analysis of the TCR binding domain of toxic shock syndrome toxin-1 predicts further diversity in MHC class II/superantigen/TCR ternary complexes
    • McCormick JK, Tripp TJ, Llera AS, Sundberg EJ, Dinges MM, Mariuzza RA, &, Schlievert PM, (2003) Functional analysis of the TCR binding domain of toxic shock syndrome toxin-1 predicts further diversity in MHC class II/superantigen/TCR ternary complexes. J Immunol 171, 1385-1392. (Pubitemid 36900071)
    • (2003) Journal of Immunology , vol.171 , Issue.3 , pp. 1385-1392
    • McCormick, J.K.1    Tripp, T.J.2    Llera, A.S.3    Sundberg, E.J.4    Dinges, M.M.5    Mariuzza, R.A.6    Schlievert, P.M.7
  • 145
    • 33746025600 scopus 로고    scopus 로고
    • Bacterial Superantigens Bypass Lck-Dependent T Cell Receptor Signaling by Activating a Gα11-Dependent, PLC-β-Mediated Pathway
    • DOI 10.1016/j.immuni.2006.04.012, PII S1074761306002998
    • Bueno C, Lemke CD, Criado G, Baroja ML, Ferguson SS, Rahman AK, Tsoukas CD, McCormick JK, &, Madrenas J, (2006) Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway. Immunity 25, 67-78. (Pubitemid 44066827)
    • (2006) Immunity , vol.25 , Issue.1 , pp. 67-78
    • Bueno, C.1    Lemke, C.D.2    Criado, G.3    Baroja, M.L.4    Ferguson, S.S.G.5    Rahman, A.K.M.N.-U.6    Tsoukas, C.D.7    McCormick, J.K.8    Madrenas, J.9
  • 146
    • 78650667875 scopus 로고    scopus 로고
    • Superantigen-induced proliferation of human CD4+CD25- T cells is followed by a switch to a functional regulatory phenotype
    • Taylor AL, &, Llewelyn MJ, (2010) Superantigen-induced proliferation of human CD4+CD25- T cells is followed by a switch to a functional regulatory phenotype. J Immunol 185, 6591-6598.
    • (2010) J Immunol , vol.185 , pp. 6591-6598
    • Taylor, A.L.1    Llewelyn, M.J.2
  • 147
    • 0019995076 scopus 로고
    • Persistent neuropsychological sequelae of toxic shock syndrome
    • 6 II
    • Rosene KA, Copass MK, Kastner LS, Nolan CM, &, Eschenbach DA, (1982) Persistent neuropsychological sequelae of toxic shock syndrome. Ann Intern Med 96, 865-870. (Pubitemid 12088885)
    • (1982) Annals of Internal Medicine , vol.96 , pp. 865-870
    • Rosene, K.A.1    Copass, M.K.2    Kastner, L.S.3
  • 149
    • 0019965140 scopus 로고
    • Staphylococcus aureus associated with toxic shock syndrome. Phage typing and toxin capability testing
    • 6 II
    • Altemeier WA, Lewis SA, Schlievert PM, Bergdoll MS, Bjornson HS, Staneck JL, &, Crass BA, (1982) Staphylococcus aureus associated with toxic shock syndrome: phage typing and toxin capability testing. Ann Intern Med 96, 978-982. (Pubitemid 12088916)
    • (1982) Annals of Internal Medicine , vol.96 , pp. 978-982
    • Altemeier, W.A.1    Lewis, S.A.2    Schlievert, P.M.3
  • 153
    • 0029031981 scopus 로고
    • Identification of class II major histocompatibility complex and T cell receptor binding sites in the superantigen toxic shock syndrome toxin 1
    • Hurley JM, Shimonkevitz R, Hanagan A, Enney K, Boen E, Malmstrom S, Kotzin BL, &, Matsumura M, (1995) Identification of class II major histocompatibility complex and T cell receptor binding sites in the superantigen toxic shock syndrome toxin 1. J Exp Med 181, 2229-2235.
    • (1995) J Exp Med , vol.181 , pp. 2229-2235
    • Hurley, J.M.1    Shimonkevitz, R.2    Hanagan, A.3    Enney, K.4    Boen, E.5    Malmstrom, S.6    Kotzin, B.L.7    Matsumura, M.8
  • 154
    • 0029844978 scopus 로고    scopus 로고
    • A mutation at glycine residue 31 of toxic shock syndrome toxin-1 defines a functional site critical for major histocompatibility complex class II binding and superantigenic activity
    • Kum WW, Wood JA, &, Chow AW, (1996) A mutation at glycine residue 31 of toxic shock syndrome toxin-1 defines a functional site critical for major histocompatibility complex class II binding and superantigenic activity. J Infect Dis 174, 1261-1270. (Pubitemid 26393905)
    • (1996) Journal of Infectious Diseases , vol.174 , Issue.6 , pp. 1261-1270
    • Kum, W.W.S.1    Wood, J.A.O.2    Chow, A.W.3
  • 155
    • 4344567024 scopus 로고    scopus 로고
    • Crystal structure of a dimeric form of streptococcal pyrogenic exotoxin A (SpeA1)
    • DOI 10.1110/ps.04826804
    • Baker MD, Gendlina I, Collins CM, &, Acharya KR, (2004) Crystal structure of a dimeric form of streptococcal pyrogenic exotoxin A (SpeA1). Protein Sci 13, 2285-2290. (Pubitemid 39128851)
    • (2004) Protein Science , vol.13 , Issue.9 , pp. 2285-2290
    • Baker, M.D.1    Gendlina, I.2    Collins, C.M.3    Acharya, K.R.4
  • 156
    • 0030932304 scopus 로고    scopus 로고
    • Analysis of the interaction between the bacterial superantigen streptococcal pyrogenic exotoxin A (SpeA) and the human T-cell receptor
    • Kline JB, &, Collins CM, (1997) Analysis of the interaction between the bacterial superantigen streptococcal pyrogenic exotoxin A (SpeA) and the human T-cell receptor. Mol Microbiol 24, 191-202. (Pubitemid 27160849)
    • (1997) Molecular Microbiology , vol.24 , Issue.1 , pp. 191-202
    • Kline, J.B.1    Collins, C.M.2
  • 157
    • 13344259321 scopus 로고    scopus 로고
    • Analysis of the superantigenic activity of mutant and allelic forms of streptococcal pyrogenic exotoxin A
    • Kline JB, &, Collins CM, (1996) Analysis of the superantigenic activity of mutant and allelic forms of streptococcal pyrogenic exotoxin A. Infect Immun 64, 861-869. (Pubitemid 26065560)
    • (1996) Infection and Immunity , vol.64 , Issue.3 , pp. 861-869
    • Bradford Kline, J.1    Collins, C.M.2
  • 159
    • 77957287814 scopus 로고    scopus 로고
    • High affinity of interaction between superantigen and T cell receptor Vbeta molecules induces a high level and prolonged expansion of superantigen-reactive CD4+ T cells
    • Omoe K, Nunomura W, Kato H, Li ZJ, Igarashi O, Araake M, Sano K, Ono HK, Abe Y, Hu DL, et al. (2010) High affinity of interaction between superantigen and T cell receptor Vbeta molecules induces a high level and prolonged expansion of superantigen-reactive CD4+ T cells. J Biol Chem 285, 30427-30435.
    • (2010) J Biol Chem , vol.285 , pp. 30427-30435
    • Omoe, K.1    Nunomura, W.2    Kato, H.3    Li, Z.J.4    Igarashi, O.5    Araake, M.6    Sano, K.7    Ono, H.K.8    Abe, Y.9    Hu, D.L.10
  • 160
    • 0025719508 scopus 로고
    • Mutation of the disulfide loop in staphylococcal enterotoxin A. Consequences for T cell recognition
    • Grossman D, Van M, Mollick JA, Highlander SK, &, Rich RR, (1991) Mutation of the disulfide loop in staphylococcal enterotoxin A. Consequences for T cell recognition. J Immunol 147, 3274-3281.
    • (1991) J Immunol , vol.147 , pp. 3274-3281
    • Grossman, D.1    Van, M.2    Mollick, J.A.3    Highlander, S.K.4    Rich, R.R.5
  • 161
    • 33845454185 scopus 로고    scopus 로고
    • Molecular basis of TCR selectivity, cross-reactivity, and allelic discrimination by a bacterial superantigen: Integrative functional and energetic mapping of the SpeC-Vβ2.1 molecular interface
    • Rahman AK, Herfst CA, Moza B, Shames SR, Chau LA, Bueno C, Madrenas J, Sundberg EJ, &, McCormick JK, (2006) Molecular basis of TCR selectivity, cross-reactivity, and allelic discrimination by a bacterial superantigen: integrative functional and energetic mapping of the SpeC-Vbeta2.1 molecular interface. J Immunol 177, 8595-8603. (Pubitemid 44893822)
    • (2006) Journal of Immunology , vol.177 , Issue.12 , pp. 8595-8603
    • Nur-Ur Rahman, A.K.M.1    Herfst, C.A.2    Moza, B.3    Shames, S.R.4    Chau, L.A.5    Bueno, C.6    Madrenas, J.7    Sundberg, E.J.8    McCormick, J.K.9
  • 162
    • 33748749713 scopus 로고    scopus 로고
    • Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule
    • DOI 10.1074/jbc.M603969200
    • Fernandez MM, Guan R, Swaminathan CP, Malchiodi EL, &, Mariuzza RA, (2006) Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule. J Biol Chem 281, 25356-25364. (Pubitemid 44401923)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.35 , pp. 25356-25364
    • Fernandez, M.M.1    Guan, R.2    Swaminathan, C.P.3    Malchiodi, E.L.4    Mariuzza, R.A.5
  • 163
    • 0037018102 scopus 로고    scopus 로고
    • Structure of a complex of the human α/β T cell receptor (TCR) HA1.7, Influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRBI*0401): Insight into TCR cross-restriction and alloreactivity
    • DOI 10.1084/jem.20011194
    • Hennecke J, &, Wiley DC, (2002) Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactivity. J Exp Med 195, 571-581. (Pubitemid 34461502)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.5 , pp. 571-581
    • Hennecke, J.1    Wiley, D.C.2


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