Analysis of the interaction between the bacterial superantigen streptococcal pyrogenic exotoxin A (SpeA) and the human T-cell receptor

Molecular Microbiology

Volumn 24, Issue 1, 1997, Pages 191-202

  Kline, J Bradford ^a   Collins, Carleen M ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EXOTOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PYROGEN; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; STREPTOCOCCUS PYOGENES; TOXIC SHOCK SYNDROME;

BACTERIA (MICROORGANISMS); SPEA; STREPTOCOCCUS PYOGENES;

EID: 0030932304     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1997.3381696.x     Document Type: Article

References (33)

1. Abe, J., Forrester, J., Nakahara, T., and Lafferty, J.A. (1991) Selective stimulation of human T cells with streptococcal erythrogenic toxins A and B. J Immunol 146: 3747-3750.
2. Alouf, J.E., Knoll, H., and Kohler, W. (1991) Sourcebook of Bacterial Protein Toxins. San Diego, California: Academic Press, Inc.
3. Bellio, M., Lone, Y., de la Calle-Martin, O., Malissen, B., Abastado, J., and Kourilsky, P. (1994) The Vβ complementarity determining region 1 of major histocompatibility complex (MHC) class I-restricted T cell receptor is involved in the recognition of peptide/MHC I and superantigen/MHC II complex. J Exp Med 179: 1087-1097.
4. Bohach, G.A., Fast, D.J., Nelson, R.D., and Schlievert, P.M. (1990) Staphylococcal and streptococcal pyrogenic toxins involved in toxic shock syndrome and related illnesses. Crit Rev Microbiol 17: 251-272.
5. Braun, M.A., Gerlach, D., Hartwig, U.F., Ozegowski, J.H., Romagne, F., Carrel, S., Kohler, W., and Fleischer, B. (1993) Stimulation of human T cells by streptococcal 'superantigen' erythrogenic toxins (Scarlet Fever Toxins). J Immunol 150: 2457-2466.
6. Chothia, C., Boswell, D.R., and Lesk, A.M. (1988) The outline structure of the T-cell α/β receptor. EMBO J 7: 3745-3755.
7. Davis, M.M., and Bjorkman, P.J. (1988) T-cell antigen receptor genes and T-cell recognition. Nature 334: 395-402.
8. Deringer, J.R., Ely, R.J., Stauffacher, C.V., and Bohach, G.A. (1996) Subtype-specific interactions of type C staphylococcal enterotoxins with the T-cell receptor. Mol Microbiol 22: 523-534.
9. Fields, B.A., Malchiodi, E.L., Li, H., Ysern, X., Stauffachers, C.V., Schlievert, P.M., Karjalainen, K., and Mariuzza, R.A. (1996) Crystal structure of a T-cell receptor β-chain complexed with a superantigen. Nature 384: 188-192.
10. Hoffman, M.L., Jablonski, L.M., Crum, K.K., Hackett, S.P., Chi, Y., Stauffacher, C.V., Stevens, D.L., and Bohach, G.A. (1994) Predictions of T-cell receptor- and major histocompatibility complex-binding sites on Staphylococcal enterotoxin C1. Infect Immun 62: 3396-3407.
11. Hoge, C.W., Schwartz, B., Talkinglon, D.F., Breiman, R.F., MacNeill, E.M., and Englender, S.J. (1993) The changing epidemiology of invasive group A streptococcal infections and the emergence of streptococcal toxic shock-like syndrome. A retrospective population-based study. JAMA 269: 384-389.
12. Hopp, T.P., and Woods, K.R. (1981) Prediction of protein antigenic determinants from amino acid sequences. Proc Natl Acad Sci USA 78: 3824-3828.
13. Hurley, J.M., Shimonkevitz, R., Hanagan, A., Enney, K., Boen, E., Malmstrom, S., Kotzin, B.L., and Matsumura, M. (1995) Identification of class II major histocompatibility complex and T cell receptor binding sites in the superantigen toxic shock syndrome toxin 1. J Exp Med 181: 2229-2235.
14. Jardetzky, T.S., Brown, J.H., Gorga, J.C., Stern, L.J., Urban, R.G., Chi, Y., Stauffacher, C., Strominger, J.L., and Wiley, D.C. (1994) Three-dimensional structure of a human class Il histocompatibility molecule complexed with superantigen. Nature 368: 711-718.
15. Kappler, J.W., Herman, A., Clements, J., and Marrack, P. (1992) Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med 175: 387-396.
16. Kimura, M. (1980) A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 16: 111-120.
17. Kline, J.B., and Collins, C.M. (1996) Analysis of the superantigenic activity of mutant and allelic forms of streptococcal pyrogenic exotoxin A. Infect Immun 64: 861-869.
18. Kumar, S., Tamura, K., and Nei, M. (1993) MEGA: Molecular Evolutionary Genetic Analysis. The Pennsylvania State University, University Park, Pennsylvania, USA.
19. Leonard, B.A.B., Lee, P.K., Jenkins, M.K., and Schlievert, P.M. (1991) Cell and receptor requirements for streptococcal pyrogenic exotoxin T-cell mitogenicity. Infect Immun 59: 1210-1214.
20. Marrack, P., and Kappler, J. (1990) The staphylococcal enterotoxins and their relatives. Science 248: 705-711.
21. Mollick, J.A., McMasters, R.L., Grossman, D., and Rich, R.R. (1993) Localization of a site on bacterial superantigens that determines T cell receptor β chain specificity. J Exp Med 177: 283-293.
22. Musser, J.M., Hauser, A.R., Kim, M.H., Schlievert, P.M., Nelson, K., and Selander, R.K. (1991) Streptococcus pyogenes causing toxic-shock-like syndrome and other invasive diseases: clonal diversity and pyrogenic exotoxin expression. Proc Natl Acad Sci USA 88: 2668-2672.
23. Musser, J.M., Kapur, V., Kanjilal, S., Shah, U., Musher, D.M., Barg, N.L., Johnston, K.H., Schlievert, P.M., Henrichsen, J., Gerlach, D., Rakita, R.M., Tanna, A., Cookson, B.D., and Huang, J.C. (1993) Geographical and temporal distribution and molecular characterization of two highly pathogenic clones of Streptococcus pyogenes expressing allelic variants of pyrogenic exotoxin A (Scarlet Fever Toxin). J Infect Dis 167: 337-345.
24. Nelson, K., Schlievert, P.M., Selander, R.K., and Musser, J.M. (1991) Characterization and clonal distribution of four alleles of the speA gene encoding pyrogenic exotoxin A (Scarlet fever toxin) in Streptococcus pyogenes. J Exp Med 174: 1271-1274.
25. Patten, P.A., Rock, E.P., Sonoda, T., St. Groth, B.F., Jorgensen, J.L., and Davis, M.M. (1993) Transfer of putative complementarity-determining region loops of T cell receptor V domains confers toxin reactivity but not peptide/MHC specificity. J Immunol 150: 2281-2294.
26. Pontzer, C.H., Irwin, M.J., Gascoigne, N.R.J., and Johnson, H.M. (1992) T-cell antigen receptor binding sites for the microbial superantigen staphylococcal enterotoxin A. Proc Natl Acad Sci USA 89: 7727-7731.
27. Schad, E.M., Zaitseva, I., Zaitsev, V.N., Dohlsten, M., Kalland, T., Schlievert, P.M., Ohlendorf, D.H., and Svensson, L.A. (1995) Crystal structure of the superantigen staphylococcal enterotoxin type A. EMBO J 14: 3292-3301.
28. Segel, I.R. (1993) Multisite and allosteric enzymes. In Enzyme Kinetics. New York: John Wiley and Sons, Inc., pp. 346-384.
29. Stevens, D.L. (1992) Invasive group A streptococcus infections. Clin Infect Dis 14: 2-13.
30. Swaminathan, S., Furey, W., Pletcher, J., and Sax, M. (1992) Crystal structure of staphylococcal enterotoxin B, a superantigen. Nature 359: 801-806.
31. Swaminathan, S., Furey, W., Pletcher, J., and Sax, M. (1995) Residues defining VB specificity in two Staphylococcal enterotoxins. Nature Struct Biol 2: 680.
32. Tomai, M.A., Schlievert, P.M., and Kotb, M. (1992) Distinct T-cell receptor Vβ gene usage by human T lymphocytes stimulated with the streptococcal pyrogenic exotoxins and pep M5 protein. Infect Immun 60: 701-705.
33. Weeks, C.R., and Ferretti, J.J. (1984) The gene for type A streptococcal exotoxin (erythrogenic toxin) is located in bacteriophage T12. Infect Immun 46: 531-536.