Broad-spectrum immunity against superantigens is elicited in mice protected from lethal shock by a superantigen antagonist peptide

Immunology Letters

Volumn 91, Issue 2-3, 2004, Pages 141-145

  Arad, Gila ^a   Hillman, Dalia ^a   Levy, Revital ^a   Kaempfer, Raymond ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

Antagonist peptide; Anti toxin antibodies; Protective immunity; Superantigen

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; IMMUNOLOGICAL ADJUVANT; PEPTIDE DERIVATIVE; STAPHYLOCOCCUS ENTEROTOXIN B; SUPERANTIGEN; THREONYLASPARAGINYLLYSYLLYSYLLYSYLVALYLTHREONYLALANYLGLUTAMINYLGLUTAMYLLEUC YLASPARTIC ACID; TOXIC SHOCK SYNDROME TOXIN 1; TOXIN ANTIBODY; TYROSYLASPARAGINYLLYSYLLYSYLLYSYLALANYLTHREONYLVALYLGLUTAMINYLGLUTAMYLLEUCY LASPARTIC ACID; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; SURVIVAL;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; B-LYMPHOCYTES; BACTERIAL PROTEINS; ENTEROTOXINS; EXOTOXINS; FEMALE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; PEPTIDES; SHOCK, SEPTIC; SUPERANTIGENS; SURVIVAL RATE; TH1 CELLS;

EID: 1542362406     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2003.11.003     Document Type: Article

References (16)

1. Janeway C.A. Jr., Yagi J., Conrad P.J., Katz M.E., Jones B., Vroegop S., Buxser S. Immunol. Rev. 107:1989;61-88.
2. Choi Y.W., Kotzin B., Herron L., Callahan J., Marrack P., Kappler J. Proc. Natl. Acad. Sci. U.S.A. 86(22):1989;8941-8945.
3. Bohach G.A., Fast D.J., Nelson R.D., Schlievert P.M. Crit. Rev. Microbiol. 17(4):1990;251-272.
4. Dinges M.M., Orwin P.M., Schlievert P.M. Clin. Microbiol. Rev. 13(1):2000;16-34.
5. Betley M.J., Mekalanos J.J. J. Bacteriol. 170(1):1988;34-41.
6. Blomster-Hautamaa D.A., Kreiswirth B.N., Kornblum J.S., Novick R.P., Schlievert P.M. J. Biol. Chem. 261(33):1986;15783-15786.
7. Arad G., Levy R., Hillman D., Kaempfer R. Nat. Med. 6(4):2000;414-421.
8. Arad G., Hillman D., Levy R., Kaempfer R. J. Leukoc. Biol. 69(6):2001;921-927.
9. Swaminathan S., Furey W., Pletcher J., Sax M. Nature. 359(6398):1992;801-806.
10. Jardetzky T.S., Brown J.H., Gorga J.C., Stern L.J., Urban R.G., Chi Y.I., Stauffacher C., Strominger J.L., Wiley D.C. Nature. 368(6473):1994;711-718.
11. Li H., Llera A., Tsuchiya D., Leder L., Ysern X., Schlievert P.M., Karjalainen K., Mariuzza R.A. Immunity. 9(6):1998;807-816.
12. Papageorgiou A.C., Tranter H.S., Acharya K.R. J. Mol. Biol. 277(1):1998;61-79.
13. Leder L., Llera A., Lavoie P.M., Lebedeva M.I., Li H., Sekaly R.P., Bohach G.A., Gahr P.J., Schlievert P.M., Karjalainen K., Mariuzza R.A. J. Exp. Med. 187(6):1998;823-833.
14. Finkelman F.D., Katona I.M., Mosmann T.R., Coffman R.L. J. Immunol. 140(4):1988;1022-1027.
15. Schlievert P.M. Nat. Med. 6(4):2000;378-379.
16. Hoffmann M.L., Jablonski L.M., Crum K.K., Hackett S.P., Chi Y.I., Stauffacher C.V., Stevens D.L., Bohach G.A. Infect. Immun. 62(8):1994;3396-3407.