Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors

EMBO Journal

Volumn 18, Issue 1, 1999, Pages 9-21

  Papageorgiou, Anastassios C ^a   Collins, Carleen M ^b   Gutman, Delia M ^b   Kline, J Bradford ^b,d   O'Brien, Susan M ^c   Tranter, Howard S ^c   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Molecular recognition; Protein crystallography; Pyrogenic exotoxin; Superantigen; Zinc binding

Indexed keywords

EXOTOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STAPHYLOCOCCUS ENTEROTOXIN; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; ZINC;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR MODEL; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE; STREPTOCOCCUS PYOGENES; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; EXOTOXINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PYROGENS; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; STREPTOCOCCUS PYOGENES; SUPERANTIGENS; T-LYMPHOCYTES;

POSIBACTERIA; SPEA; STAPHYLOCOCCUS; STREPTOCOCCUS PYOGENES;

EID: 0033521685     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.1.9     Document Type: Article

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