Acute systemic immune activation following vaginal exposure to staphylococcal enterotoxin B-Implications for menstrual shock

Journal of Reproductive Immunology

Volumn 73, Issue 1, 2007, Pages 51-59

  Rajagopalan, Govindarajan ^a   Smart, Michele K ^a   Murali, Narayana ^b   Patel, Robin ^b   David, Chella S ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b Mayo Clinic   (United States)

Author keywords

Inflammation; Menstrual shock; Staphylococcus aureus; Superantigens; Vagina

Indexed keywords

CYTOKINE; HLA ANTIGEN CLASS 2; STAPHYLOCOCCUS ENTEROTOXIN B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL INFILTRATION; CONTROLLED STUDY; ESTRUS CYCLE; EXPOSURE; FEMALE; LEUKOCYTE; LIVER; LUNG; LYMPHOID ORGAN; MENSTRUATION DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; THYMOCYTE; TOXIC SHOCK SYNDROME; TRANSGENIC MOUSE; VAGINA;

ANIMALS; ENTEROTOXINS; FEMALE; LIVER; LUNG; MENSTRUATION; MICE; SHOCK, SEPTIC; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; T-LYMPHOCYTES; VAGINA;

EID: 33846537280     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2006.06.007     Document Type: Article

References (41)

1. Abram A.C., Bellian K.T., Giles W.J., and Gross C.W. Toxic shock syndrome after functional endonasal sinus surgery: an all or none phenomenon?. Laryngoscope 104 (1994) 927-931
2. Andrews M.M., Parent E.M., Barry M., and Parsonnet J. Recurrent non-menstrual toxic shock syndrome: clinical manifestations, diagnosis, and treatment. Clin. Infect. Dis. 32 (2001) 1470-1479
3. Banks M.C., Kamel N.S., Zabriskie J.B., Larone D.H., Ursea D., and Posnett D.N. Staphylococcus aureus express unique superantigens depending on the tissue source. J. Infect. Dis. 187 (2003) 77-86
4. Brown W.J. Variations in the vaginal bacterial flora: a preliminary report. Ann. Intern. Med. 96 (1982) 931-934
5. Cardona I.D., Goleva E., Ou L.S., and Leung D.Y. Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes. J. Allergy Clin. Immunol. 117 (2006) 688-695
6. Chesney P.J., Bergdoll M.S., Davis J.P., and Vergeront J.M. The disease spectrum, epidemiology, and etiology of toxic-shock syndrome. Ann. Rev. Microbiol. 38 (1984) 315-338
7. Chow A.W., Bartlett K.H., Percival-Smith R., and Morrison B.J. Vaginal colonization with Staphylococcus aureus, positive for toxic-shock marker protein, and Escherichia coli in healthy women. J. Infect. Dis. 150 (1984) 80-84
8. DaSilva L., Welcher B.C., Ulrich R.G., Aman M.J., David C.S., and Bavari S. Human-like immune response of human leukocyte antigen-Dr3 transgenic mice to staphylococcal enterotoxins: a novel model for superantigen vaccines. J. Infect. Dis. 185 (2002) 1754-1760
9. Davis C.C., Kremer M.J., Schlievert P.M., and Squier C.A. Penetration of toxic shock syndrome toxin-1 across porcine vaginal mucosa ex vivo: permeability characteristics, toxin distribution, and tissue damage. Am. J. Obstet. Gynecol. 189 (2003) 1785-1791
10. Dinges M.M., Orwin P.M., and Schlievert P.M. Exotoxins of Staphylococcus aureus. Clin. Microbiol. Rev. 13 (2000) 16-34
11. Flood J.A., Tripp T.J., Davis C.C., Hill D.R., and Schlievert P.M. A toroid model for in vitro investigations of toxic shock syndrome toxin-1 production. J. Microbiol. Methods 57 (2004) 283-288
12. Guinan M.E., Dan B.B., Guidotti R.J., Reingold A.L., Schmid G.P., Bettoli E.J., Lossick J.G., Shands K.N., Kramer M.A., Hargrett N.T., Anderson R.L., and Broome C.V. Vaginal colonization with Staphylococcus aureus in healthy women: a review of four studies. Ann. Intern. Med. 96 (1982) 944-947
13. Herzer C.M. Toxic shock syndrome: broadening the differential diagnosis. J. Am. Board Fam. Pract. 14 (2001) 131-136
14. Kass E.H., Kendrick M.I., Tsai Y.C., and Parsonnet J. Interaction of magnesium ion, oxygen tension, and temperature in the production of toxic shock syndrome toxin-1 by Staphylococcus aureus. J. Infect. Dis. 155 (1987) 812-815
15. Kishimoto H., Surh C.D., and Sprent J. A role for Fas in negative selection of thymocytes in vivo. J. Exp. Med. 187 (1998) 1427-1438
16. Kotzin B.L., Leung D.Y., Kappler J., and Marrack P. Superantigens and their potential role in human disease. Adv. Immunol. 54 (1993) 99-166
17. Li H., Llera A., Malchiodi E.L., and Mariuzza R.A. The structural basis of T cell activation by superantigens. Ann. Rev. Immunol. 17 (1999) 435-466
18. Linnemann Jr. C.C., Staneck J.L., Hornstein S., Barden T.P., Rauh J.L., Bonventre P.F., Buncher C.R., and Beiting A. The epidemiology of genital colonization with Staphylococcus aureus. Ann. Intern. Med. 96 (1982) 940-944
19. Martin R.R., Buttram V., Besch P., Kirkland J.J., and Petty G.P. Nasal and vaginal Staphylococcus aureus in young women: quantitative studies. Ann. Intern. Med. 96 (1982) 951-953
20. McCormick J.K., Yarwood J.M., and Schlievert P.M. Toxic shock syndrome and bacterial superantigens: an update. Ann. Rev. Microbiol. 55 (2001) 77-104
21. Mills J.T., Parsonnet J., Tsai Y.C., Kendrick M., Hickman R.K., and Kass E.H. Control of production of toxic shock syndrome toxin-1 (Tsst-1) by magnesium ion. J. Infect. Dis. 151 (1985) 1158-1161
22. Morgan E., Varro R., Sepulveda H., Ember J.A., Apgar J., Wilson J., Lowe L., Chen R., Shivraj L., Agadir A., Campos R., Ernst D., and Gaur A. Cytometric bead array: a multiplexed assay platform with applications in various areas of biology. Clin. Immunol. 110 (2004) 252-266
23. Nashev D., Toshkova K., Salasia S.I., Hassan A.A., Lammler C., and Zschock M. Distribution of virulence genes of Staphylococcus aureus isolated from stable nasal carriers. FEMS Microbiol. Lett. 233 (2004) 45-52
24. Ou L.S., Goleva E., Hall C., and Leung D.Y. T regulatory cells in atopic dermatitis and subversion of their activity by superantigens. J. Allergy Clin. Immunol. 113 (2004) 756-763
25. Parsonnet J., Hansmann M.A., Delaney M.L., Modern P.A., DuBois A.M., Wieland-Alter W., Wissemann K.W., Wild J.E., Jones M.B., Seymour J.L., and Onderdonk A.B. Prevalence of toxic shock syndrome toxin 1-producing Staphylococcus aureus and the presence of antibodies to this superantigen in menstruating women. J. Clin. Microbiol. 43 (2005) 4628-4634
26. Proft T., and Fraser J.D. Bacterial superantigens. Clin. Exp. Immunol. 133 (2003) 299-306
27. Rago J.V., and Schlievert P.M. Mechanisms of pathogenesis of staphylococcal and streptococcal superantigens. Curr. Top. Microbiol. Immunol. 225 (1998) 81-97
28. Rajagopalan G., Smart M.K., Marietta E.V., and David C.S. Staphylococcal enterotoxin B-induced activation and concomitant resistance to cell death in CD28-deficient HLA-DQ8 transgenic mice. Int. Immunol. 14 (2002) 801-812
29. Rajagopalan G., Smart M.K., Krco C.J., and David C.S. Expression and function of transgenic HLA-DQ molecules and lymphocyte development in mice lacking invariant chain. J. Immunol. 169 (2002) 1774-1783
30. Rajagopalan G., Smart M.K., Cheng S., Krco C.J., Johnson K.L., and David C.S. Expression and function of HLA-DR3 and DQ8 in transgenic mice lacking functional H2-M. Tissue Antigens 62 (2003) 149-161
31. Rajagopalan G., Singh M., Sen M., Murali N., Nath K.A., and David C.S. Endogenous superantigens shape response to exogenous superantigens. Clin. Diagn. Lab. Immunol. 12 (2005) 1119-1122
32. Rajagopalan G., Iijima K., Singh M., Kita H., Patel R., and David C.S. Intranasal exposure to bacterial superantigens induces airway inflammation in HLA Class Ii transgenic mice. Infect. Immun. 74 (2006) 1284-1296
33. Rajagopalan G., Sen M., Singh M., Murali N., Nath K.A., Iijima K., Kita H., Leontovich A.A., Unnikrishnan G., Patel R., and David C.S. Intranasal exposure to staphylococcal enterotoxin B elicits an acute systemic inflammatory response. Shock 25 (2006) 647-656
34. Roy C.J., Warfield K.L., Welcher B.C., Gonzales R.F., Larsen T., Hanson J., David C.S., Krakauer T., and Bavari S. Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin B. Infect. Immunol. 73 (2005) 2452-2460
35. Samarkos M., and Vaiopoulos G. The role of infections in the pathogenesis of autoimmune diseases. Curr. Drug Targets Inflamm. Allergy 4 (2005) 99-103
36. Schlievert P.M. Effect of magnesium on production of toxic shock syndrome toxin-1 by Staphylococcus aureus. J. Infect. Dis. 152 (1985) 618-620
37. Schlievert P.M., Jablonski L.M., Roggiani M., Sadler I., Callantine S., Mitchell D.T., Ohlendorf D.H., and Bohach G.A. Pyrogenic toxin superantigen site specificity in toxic shock syndrome and food poisoning in animals. Infect. Immun. 68 (2000) 3630-3634
38. Vermot J., Fraulob V., Dolle P., and Niederreither K. Expression of enzymes synthesizing (aldehyde dehydrogenase 1 and retinaldehyde dehydrogenase 2) and metabolizing (Cyp26) retinoic acid in the mouse female reproductive system. Endocrinology 141 (2000) 3638-3645
39. Wagner R., and Toback J.M. Toxic shock syndrome following septoplasty using plastic septal splints. Laryngoscope 96 (1986) 609-610
40. Warner J.E., and Onderdonk A.B. Diversity of toxic shock syndrome toxin 1-positive Staphylococcus aureus isolates. Appl. Environ. Microbiol. 70 (2004) 6931-6935
41. Wucherpfennig K.W. Mechanisms for the induction of autoimmunity by infectious agents. J. Clin. Invest. 108 (2001) 1097-1104