Crystal Structure of the Streptococcal Superantigen SpeI and Functional Role of a Novel Loop Domain in T Cell Activation by Group V Superantigens

Journal of Molecular Biology

Volumn 367, Issue 4, 2007, Pages 925-934

  Brouillard, Jean Nicholas P ^a,b   Günther, Sebastian ^c   Varma, Ashok K ^c   Gryski, Irene ^a,b   Herfst, Christine A ^a,b   Rahman, A K M Nur ur ^a,b   Leung, Donald Y M ^d   Schlievert, Patrick M ^e   Madrenas, Joaquín ^a,f   Sundberg, Eric J ^c   McCormick, John K ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^c BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^f ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

Streptococcus pyogenes; superantigens; T cell receptor

Indexed keywords

BACTERIAL TOXIN; GLYCINE; PROTEIN SUBUNIT; STREPTOCOCCAL PYROGENIC EXOTOXIN I; STREPTOCOCCUS ANTIGEN; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ANTIGEN FUNCTION; ANTIGEN RECOGNITION; ANTIGEN STRUCTURE; ARTICLE; BETA CHAIN; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; STREPTOCOCCUS PYOGENES; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; T LYMPHOCYTE ACTIVATION; TOXIN ANALYSIS;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS PYOGENES;

EID: 33847723413     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.01.024     Document Type: Article

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