-
1
-
-
9644283089
-
Global data on visual impairment in the year 2002
-
Resnikoff S, Pascolini D, Etya'ale D et al. Global data on visual impairment in the year 2002. Bull. World Health Organ. 82, 844-851 (2004) (Pubitemid 39573742)
-
(2004)
Bulletin of the World Health Organization
, vol.82
, Issue.11
, pp. 844-851
-
-
Resnikoff, S.1
Pascolini, D.2
Etya'ale, D.3
Kocur, I.4
Pararajasegaram, R.5
Pokharel, G.P.6
Mariotti, S.P.7
-
2
-
-
77951295054
-
Complications of intravitreal injections
-
Sampat KM, Garg SJ. Complications of intravitreal injections. Curr. Opin. Ophthalmol. 21, 178-183 (2010)
-
(2010)
Curr. Opin. Ophthalmol.
, vol.21
, pp. 178-183
-
-
Sampat, K.M.1
Garg, S.J.2
-
3
-
-
34848928410
-
Intravitreal injections of GDNF-loaded biodegradable microspheres are neuroprotective in a rat model of glaucoma
-
Jiang C, Moore MJ, Zhang X, Klassen H, Langer R, Young M. Intravitreal injections of GDNF-loaded biodegradable microspheres are neuroprotective in a rat model of glaucoma. Mol. Vis. 13, 1783-1792 (2007) (Pubitemid 47497006)
-
(2007)
Molecular Vision
, vol.13
, pp. 1783-1792
-
-
Jiang, C.1
Moore, M.J.2
Zhang, X.3
Klassen, H.4
Langer, R.5
Young, M.6
-
4
-
-
33751268869
-
Intraocular implants for extended drug delivery: Therapeutic applications
-
DOI 10.1016/j.addr.2006.07.026, PII S0169409X06001645
-
Bourges JL, Bloquel C. Thomas A et al. Intraocular implants for extended drug delivery: therapeutic applications. Adv. Drug Delivery Rev. 58, 1182-1202 (2006) (Pubitemid 44794429)
-
(2006)
Advanced Drug Delivery Reviews
, vol.58
, Issue.11
, pp. 1182-1202
-
-
Bourges, J.L.1
Bloquel, C.2
Thomas, A.3
Froussart, F.4
Bochot, A.5
Azan, F.6
Gurny, R.7
BenEzra, D.8
Behar-Cohen, F.9
-
5
-
-
77951282109
-
A review of implantable intravitreal drug delivery technologies for the treatment of posterior segment eye diseases
-
Choonara YE, Pillay V, Danckwerts MP, Carmichael TR, du Toit LC. A review of implantable intravitreal drug delivery technologies for the treatment of posterior segment eye diseases. J. Pharm. Sci. 99, 2219-2239 (2010)
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 2219-2239
-
-
Choonara, Y.E.1
Pillay, V.2
Danckwerts, M.P.3
Carmichael, T.R.4
Du Toit, L.C.5
-
6
-
-
33751192060
-
Transscleral drug delivery to the posterior eye: Prospects of pharmacokinetic modeling
-
Ranta VP, Urtti A. Transscleral drug delivery to the posterior eye: prospects of pharmacokinetic modeling. Adv. Drug Deliv. Rev. 58, 1164-1181 (2006)
-
(2006)
Adv. Drug Deliv. Rev.
, vol.58
, pp. 1164-1181
-
-
Ranta, V.P.1
Urtti, A.2
-
8
-
-
79952450877
-
Drug delivery to the posterior segment of the eye
-
Thrimawithana TR, Young S, Bunt CR, Green C, Alany RG. Drug delivery to the posterior segment of the eye. Drug Discov. Today 16, 270-277 (2011)
-
(2011)
Drug Discov. Today
, vol.16
, pp. 270-277
-
-
Thrimawithana, T.R.1
Young, S.2
Bunt, C.R.3
Green, C.4
Alany, R.G.5
-
9
-
-
39149121847
-
Current and future ophthalmic drug delivery systems a shift to the posterior segment
-
Del Amo EM, Urtti A. Current and future ophthalmic drug delivery systems. A shift to the posterior segment. Drug Discov. Today 13, 135-143 (2008)
-
(2008)
Drug Discov. Today
, vol.13
, pp. 135-143
-
-
Del Amo, E.M.1
Urtti, A.2
-
10
-
-
77953173751
-
New techniques for drug delivery to the posterior eye segment
-
Eljarrat-Binstock E, Pe'er J, Domb AJ. New techniques for drug delivery to the posterior eye segment. Pharm. Res. 27, 530-543 (2010)
-
(2010)
Pharm. Res.
, vol.27
, pp. 530-543
-
-
Eljarrat-Binstock, E.1
Peer, J.2
Domb, A.J.3
-
11
-
-
77958198693
-
Ocular drug delivery
-
Gaudana R, Ananthula HK, Parenky A, Mitra AK. Ocular drug delivery. AAPS J. 12, 348-360 (2010)
-
(2010)
AAPS J.
, vol.12
, pp. 348-360
-
-
Gaudana, R.1
Ananthula, H.K.2
Parenky, A.3
Mitra, A.K.4
-
12
-
-
84925940671
-
Drug delivery to the posterior segment of the eye
-
Kuppermann BD, Loewenstein A. Drug delivery to the posterior segment of the eye. Dev. Ophthalmol. 47, 59-72 (2010)
-
(2010)
Dev. Ophthalmol.
, vol.47
, pp. 59-72
-
-
Kuppermann, B.D.1
Loewenstein, A.2
-
15
-
-
35048821557
-
Transport barriers in transscleral drug delivery for retinal diseases
-
DOI 10.1159/000108117
-
Kim SH, Lutz RJ, Wang NS, Robinson MR. Transport barriers in transscleral drug delivery for retinal diseases. Ophthalmic Res. 39, 244-254 (2007) (Pubitemid 47557244)
-
(2007)
Ophthalmic Research
, vol.39
, Issue.5
, pp. 244-254
-
-
Kim, S.H.1
Lutz, R.J.2
Wang, N.S.3
Robinson, M.R.4
-
16
-
-
77950924888
-
Delivery of anti-angiogenic molecular therapies for retinal disease
-
Anderson OA, Bainbridge JW, Shima DT. Delivery of anti-angiogenic molecular therapies for retinal disease. Drug Discov. Today 15, 272-282 (2010)
-
(2010)
Drug Discov. Today
, vol.15
, pp. 272-282
-
-
Anderson, O.A.1
Bainbridge, J.W.2
Shima, D.T.3
-
17
-
-
69449091997
-
Experimental and clinical evidence of neuroprotection by nerve growth factor eye drops: Implications for glaucoma
-
USA
-
Lambiase A, Aloe L, Centofanti M et al. Experimental and clinical evidence of neuroprotection by nerve growth factor eye drops: implications for glaucoma. Proc. Natl Acad. Sci. USA 106, 13469-13474 (2009)
-
(2009)
Proc. Natl Acad. Sci.
, vol.106
, pp. 13469-13474
-
-
Lambiase, A.1
Aloe, L.2
Centofanti, M.3
-
18
-
-
79955032437
-
Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration
-
USA
-
Zhang K, Hopkins JJ, Heier JS et al. Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration. Proc. Natl Acad. Sci. USA 108, 6241-6245 (2011)
-
(2011)
Proc. Natl Acad. Sci.
, vol.108
, pp. 6241-6245
-
-
Zhang, K.1
Hopkins, J.J.2
Heier, J.S.3
-
19
-
-
78649448567
-
Protein delivery for retinal diseases: From basic considerations to clinical applications
-
El Sanharawi M, Kowalczuk L, Touchard E, Omri S, de Kozak Y, Behar-Cohen F. Protein delivery for retinal diseases: from basic considerations to clinical applications. Prog. Retinal Eye Res. 29, 443-465 (2010)
-
(2010)
Prog. Retinal Eye Res.
, vol.29
, pp. 443-465
-
-
El Sanharawi, M.1
Kowalczuk, L.2
Touchard, E.3
Omri, S.4
De Kozak, Y.5
Behar-Cohen, F.6
-
20
-
-
33751172532
-
Ocular delivery of nucleic acids: Antisense oligonucleotides aptamers and siRNA
-
Fattal E, Bochot A. Ocular delivery of nucleic acids: antisense oligonucleotides, aptamers and siRNA. Adv. Drug Deliv. Rev. 58, 1203-1223 (2006)
-
(2006)
Adv. Drug Deliv. Rev.
, vol.58
, pp. 1203-1223
-
-
Fattal, E.1
Bochot, A.2
-
22
-
-
0024135845
-
Chain conformation of linear polyelectrolyte in salt solutions: Sodium poly styrene sulfonate in potassium chloride and sodium chloride solutions
-
Wang L, Yu H. Chain conformation of linear polyelectrolyte in salt solutions: sodium poly(styrene sulfonate) in potassium chloride and sodium chloride solutions. Macromolecules 21, 3498-3501 (1988)
-
(1988)
Macromolecules
, vol.21
, pp. 3498-3501
-
-
Wang, L.1
Yu, H.2
-
23
-
-
78650394814
-
Effects of charge on antibody tissue distribution and pharmacokinetics
-
Boswell CA, Tesar DB, Mukhyala K, Theil FP, Fielder PJ, Khawli LA. Effects of charge on antibody tissue distribution and pharmacokinetics. Bioconjug. Chem. 21(12), 2153-2163 (2010)
-
(2010)
Bioconjug. Chem.
, vol.21
, Issue.12
, pp. 2153-2163
-
-
Boswell, C.A.1
Tesar, D.B.2
Mukhyala, K.3
Theil, F.P.4
Fielder, P.J.5
Khawli, L.A.6
-
24
-
-
0026611375
-
Conjunctival penetration of insulin and peptide drugs in the albino rabbit
-
Hayakawa E, Chien DS, Inagaki K, Yamamoto A, Wang W, Lee VH. Conjunctival penetration of insulin and peptide drugs in the albino rabbit. Pharm. Res. 9, 769-775 (1992)
-
(1992)
Pharm. Res.
, vol.9
, pp. 769-775
-
-
Hayakawa, E.1
Chien, D.S.2
Inagaki, K.3
Yamamoto, A.4
Wang, W.5
Lee, V.H.6
-
25
-
-
20444378182
-
Roles of the conjunctiva in ocular drug delivery: A review of conjunctival transport mechanisms and their regulation
-
DOI 10.1016/j.ejpb.2004.12.007, PII S0939641105000159
-
Hosoya K, Lee VH, Kim KJ. Roles of the conjunctiva in ocular drug delivery: a review of conjunctival transport mechanisms and their regulation. Eur. J. Pharm. Biopharm. 60, 227-240 (2005) (Pubitemid 40804563)
-
(2005)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.60
, Issue.2
, pp. 227-240
-
-
Hosoya, K.-I.1
Lee, V.H.L.2
Kim, K.-J.3
-
26
-
-
0034533874
-
Modification of ocular permeability of peptide drugs by absorption promoters
-
Sasaki H, Yamamura K, Mukai T et al. Modification of ocular permeability of peptide drugs by absorption promoters. Biol. Pharm. Bull. 23, 1524-1527 (2000) (Pubitemid 32016323)
-
(2000)
Biological and Pharmaceutical Bulletin
, vol.23
, Issue.12
, pp. 1524-1527
-
-
Sasaki, H.1
Yamamura, K.2
Mukai, T.3
Nishida, K.4
Nakamura, J.5
Nakashima, M.6
Ichikawa, M.7
-
27
-
-
0029015127
-
Ocular permeability of FITC-dextran with absorption promoter for ocular delivery of peptide drug
-
Sasaki H, Yamamura K, Tei C, Nishida K, Nakamura J. Ocular permeability of FITC-dextran with absorption promoter for ocular delivery of peptide drug. J. Drug Target. 3, 129-135 (1995)
-
(1995)
J. Drug Target.
, vol.3
, pp. 129-135
-
-
Sasaki, H.1
Yamamura, K.2
Tei, C.3
Nishida, K.4
Nakamura, J.5
-
28
-
-
0030862682
-
Polar solute transport across the pigmented rabbit conjunctiva: Size dependence and the influence of 8-bromo cyclic adenosine monophosphate
-
DOI 10.1023/A:1012123411343
-
Horibe Y, Hosoya K, Kim KJ, Ogiso T, Lee VH. Polar solute transport across the pigmented rabbit conjunctiva: size dependence and the influence of 8-bromo cyclic adenosine monophosphate. Pharm. Res. 14, 1246-1251 (1997) (Pubitemid 27432551)
-
(1997)
Pharmaceutical Research
, vol.14
, Issue.9
, pp. 1246-1251
-
-
Horibe, Y.1
Hosoya, K.-I.2
Kim, K.-J.3
Ogiso, T.4
Lee, V.H.L.5
-
29
-
-
68349106079
-
Pharmacokinetics of bevacizumab after topical subconjunctival and intravitreal administration in rabbits
-
Nomoto H, Shiraga F, Kuno N et al. Pharmacokinetics of bevacizumab after topical, subconjunctival, and intravitreal administration in rabbits. Invest. Ophthalmol. Vis. Sci. 50, 4807-4813 (2009)
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 4807-4813
-
-
Nomoto, H.1
Shiraga, F.2
Kuno, N.3
-
30
-
-
77954314021
-
Topical and intravitreous administration of cationic nanoemulsions to deliver antisense oligonucleotides directed towards VEGF KDR receptors to the eye
-
Hagigit T, Abdulrazik M, Orucov F et al. Topical and intravitreous administration of cationic nanoemulsions to deliver antisense oligonucleotides directed towards VEGF KDR receptors to the eye. J. Control. Release 145, 297-305 (2010)
-
(2010)
J. Control. Release
, vol.145
, pp. 297-305
-
-
Hagigit, T.1
Abdulrazik, M.2
Orucov, F.3
-
31
-
-
59449086444
-
Pharmacokinetics and posterior segment biodistribution of ESBA105 an anti-TNF-A single-chain antibody upon topical administration to the rabbit eye
-
Furrer E, Berdugo M, Stella C et al. Pharmacokinetics and posterior segment biodistribution of ESBA105, an anti-TNF-a single-chain antibody, upon topical administration to the rabbit eye. Invest. Ophthalmol. Vis. Sci. 50, 771-778 (2009)
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 771-778
-
-
Furrer, E.1
Berdugo, M.2
Stella, C.3
-
32
-
-
59449107918
-
Efficient intraocular penetration of topical anti-TNF-A single-chain antibody ESBA105 to anterior and posterior segment without penetration enhancer
-
Ottiger M, Thiel MA, Feige U, Lichtlen P, Urech DM. Efficient intraocular penetration of topical anti-TNF-a single-chain antibody (ESBA105) to anterior and posterior segment without penetration enhancer. Invest. Ophthalmol. Vis. Sci. 50, 779-786 (2009)
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 779-786
-
-
Ottiger, M.1
Thiel, M.A.2
Feige, U.3
Lichtlen, P.4
Urech, D.M.5
-
33
-
-
0021842646
-
Importance of the noncorneal absorption route in topical ophthalmic drug delivery
-
Ahmed I, Patton TF. Importance of the noncorneal absorption route in topical ophthalmic drug deliveryInvest. Ophthalmol. Vis. Sci. 26, 584-587 (1985) (Pubitemid 15059025)
-
(1985)
Investigative Ophthalmology and Visual Science
, vol.26
, Issue.4
, pp. 584-587
-
-
Ahmed, I.1
Patton, T.F.2
-
34
-
-
0036272393
-
Intraocular distribution of 70-kDa dextran after subconjunctival injection in mice
-
Kim TW, Lindsey JD, Aihara M, Anthony TL, Weinreb RN. Intraocular distribution of 70-kDa dextran after subconjunctival injection in mice. Invest. Ophthalmol. Vis. Sci. 43, 1809-1816 (2002) (Pubitemid 34587025)
-
(2002)
Investigative Ophthalmology and Visual Science
, vol.43
, Issue.6
, pp. 1809-1816
-
-
Kim, T.W.1
Lindsey, J.D.2
Aiara, M.3
Anthony, T.L.4
Weinreb, R.N.5
-
35
-
-
48449087212
-
Subconjunctival antisense oligonucleotides targeting TNF-A influence immunopathology and viral replication in murine HSV-1 retinitis
-
Li J, Wasmuth S, Bauer D, Baehler H, Hennig M, Heiligenhaus A. Subconjunctival antisense oligonucleotides targeting TNF-a influence immunopathology and viral replication in murine HSV-1 retinitis. Graefes Arch. Clin. Exp. Ophthalmol. 246, 1265-1273 (2008)
-
(2008)
Graefes Arch. Clin. Exp. Ophthalmol.
, vol.246
, pp. 1265-1273
-
-
Li, J.1
Wasmuth, S.2
Bauer, D.3
Baehler, H.4
Hennig, M.5
Heiligenhaus, A.6
-
36
-
-
0038742908
-
Periocular injection of an adenoviral vector encoding pigment epithelium-derived factor inhibits choroidal neovascularization
-
DOI 10.1038/sj.gt.3301931
-
Gehlbach P, Demetriades AM, Yamamoto S et al. Periocular injection of an adenoviral vector encoding pigment epithelium-derived factor inhibits choroidal neovascularization. Gene Ther. 10, 637-646 (2003) (Pubitemid 36553609)
-
(2003)
Gene Therapy
, vol.10
, Issue.8
, pp. 637-646
-
-
Gehlbach, P.1
Demetriades, A.M.2
Yamamoto, S.3
Deering, T.4
Duh, E.J.5
Yang, H.S.6
Cingolani, C.7
Lai, H.8
Wei, L.9
Campochiaro, P.A.10
-
37
-
-
40549145573
-
Drug elimination kinetics following subconjunctival injection using dynamic contrast-enhanced magnetic resonance imaging
-
DOI 10.1007/s11095-007-9408-z
-
Kim SH, Csaky KG, Wang NS, Lutz RJ. Drug elimination kinetics following subconjunctival injection using dynamic contrast-enhanced magnetic resonance imaging. Pharm. Res. 25, 512-520 (2008) (Pubitemid 351357728)
-
(2008)
Pharmaceutical Research
, vol.25
, Issue.3
, pp. 512-520
-
-
Kim, S.H.1
Csaky, K.G.2
Wang, N.S.3
Lutz, R.J.4
-
38
-
-
0031696683
-
Fiber Matrix Model of Sclera and Corneal Stroma for Drug Delivery to the Eye
-
Edwards A, Prausnitz MR. Fiber matrix model of sclera and corneal stroma for drug delivery to the eye. AIChE J. 44, 214-225 (1998) (Pubitemid 128485306)
-
(1998)
AIChE Journal
, vol.44
, Issue.1
, pp. 214-225
-
-
Edwards, A.1
Prausnitz, M.R.2
-
39
-
-
0033695008
-
The effect of hydration and matrix composition on solute diffusion in rabbit sclera
-
Boubriak OA, Urban JP, Akhtar S, Meek KM, Bron AJ. The effect of hydration and matrix composition on solute diffusion in rabbit sclera. Exp. Eye Res. 71, 503-514 (2000)
-
(2000)
Exp. Eye Res.
, vol.71
, pp. 503-514
-
-
Boubriak, O.A.1
Urban, J.P.2
Akhtar, S.3
Meek, K.M.4
Bron, A.J.5
-
41
-
-
0029097631
-
Human scleral permeability effects of age cryotherapy transscleral diode laser and surgical thinning
-
Olsen TW, Edelhauser HF, Lim JI, Geroski DH. Human scleral permeability. Effects of age, cryotherapy, transscleral diode laser, and surgical thinning. Invest. Ophthalmol. Vis. Sci. 36, 1893-1903 (1995)
-
(1995)
Invest. Ophthalmol. Vis. Sci.
, vol.36
, pp. 1893-1903
-
-
Olsen, T.W.1
Edelhauser, H.F.2
Lim, J.I.3
Geroski, D.H.4
-
42
-
-
0034031474
-
Diffusion of high molecular weight compounds through sclera
-
Ambati J, Canakis CS, Miller JW et al. Diffusion of high molecular weight compounds through sclera. Invest. Ophthalmol. Vis. Sci. 41, 1181-1185 (2000) (Pubitemid 30187558)
-
(2000)
Investigative Ophthalmology and Visual Science
, vol.41
, Issue.5
, pp. 1181-1185
-
-
Ambati, J.1
Canakis, C.S.2
Miller, J.W.3
Gragoudas, E.S.4
Edwards, A.5
Weissgold, D.J.6
Kim, I.7
Delori, F.C.8
Adamis, A.P.9
-
43
-
-
79955010309
-
Sclera-choroid-RPE transport of eight b-blockers in human bovine porcine rabbit and rat models
-
Kadam RS, Cheruvu NP, Edelhauser HF, Kompella UB. Sclera-choroid-RPE transport of eight b-blockers in human, bovine, porcine, rabbit, and rat models. Invest. Ophthalmol. Vis. Sci. 52(8), 5387-5399 (2011)
-
(2011)
Invest. Ophthalmol. Vis. Sci.
, vol.52
, Issue.8
, pp. 5387-5399
-
-
Kadam, R.S.1
Cheruvu, N.P.2
Edelhauser, H.F.3
Kompella, U.B.4
-
44
-
-
60849116132
-
Porcine sclera as a model of human sclera for in vitro transport experiments: Histology SEM and comparative permeability
-
Nicoli S, Ferrari G, Quarta M et al. Porcine sclera as a model of human sclera for in vitro transport experiments: histology, SEM, and comparative permeability. Mol. Vis. 15, 259-266 (2009)
-
(2009)
Mol. Vis.
, vol.15
, pp. 259-266
-
-
Nicoli, S.1
Ferrari, G.2
Quarta, M.3
-
45
-
-
0031772606
-
Permeability of cornea sclera and conjunctiva: A literature analysis for drug delivery to the eye
-
Prausnitz MR, Noonan JS. Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye. J. Pharm. Sci. 87, 1479-1488 (1998)
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 1479-1488
-
-
Prausnitz, M.R.1
Noonan, J.S.2
-
46
-
-
38549147909
-
Determining accurate molecular sizes in solution through NMR diffusion spectroscopy
-
Macchioni A, Ciancaleoni G, Zuccaccia C, Zuccaccia D. Determining accurate molecular sizes in solution through NMR diffusion spectroscopy. Chem. Soc. Rev. 37, 479-489 (2008)
-
(2008)
Chem. Soc. Rev.
, vol.37
, pp. 479-489
-
-
Macchioni, A.1
Ciancaleoni, G.2
Zuccaccia, C.3
Zuccaccia, D.4
-
47
-
-
78549283092
-
Influence of permeant lipophilicity on permeation across human sclera
-
Wen H, Hao J, Li SK. Influence of permeant lipophilicity on permeation across human sclera. Pharm. Res. 27, 2446-2456 (2010)
-
(2010)
Pharm. Res.
, vol.27
, pp. 2446-2456
-
-
Wen, H.1
Hao, J.2
Li, S.K.3
-
48
-
-
77249128589
-
Influence of lipophilicity on drug partitioning into sclera choroid-retinal pigment epithelium retina trabecular meshwork and optic nerve
-
Kadam RS, Kompella UB. Influence of lipophilicity on drug partitioning into sclera, choroid-retinal pigment epithelium, retina, trabecular meshwork, and optic nerve. J. Pharmacol. Exp. Ther. 332, 1107-1120 (2010)
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, pp. 1107-1120
-
-
Kadam, R.S.1
Kompella, U.B.2
-
49
-
-
79955045075
-
Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids
-
Thakur A, Kadam RS, Kompella UB. Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids. Drug Metab. Dispos. 39, 771-781 (2011)
-
(2011)
Drug Metab. Dispos.
, vol.39
, pp. 771-781
-
-
Thakur, A.1
Kadam, R.S.2
Kompella, U.B.3
-
50
-
-
33750602659
-
Bovine and porcine transscleral solute transport: Influence of lipophilicity and the choroid-Bruch's layer
-
DOI 10.1167/iovs.06-0404
-
Cheruvu NP, Kompella UB. Bovine and porcine transscleral solute transport: influence of lipophilicity and the Choroid-Bruch's layer. Invest. Ophthalmol. Vis. Sci. 47, 4513-4522 (2006) (Pubitemid 46579380)
-
(2006)
Investigative Ophthalmology and Visual Science
, vol.47
, Issue.10
, pp. 4513-4522
-
-
Cheruvu, N.P.S.1
Kompella, U.B.2
-
51
-
-
33847301369
-
Transscleral diffusion of ethacrynic acid and sodium fluorescein
-
Lin CW, Wang Y, Challa P, Epstein DL, Yuan F. Transscleral diffusion of ethacrynic acid and sodium fluorescein. Mol. Vis. 13, 243-251 (2007) (Pubitemid 46323082)
-
(2007)
Molecular Vision
, vol.13
, pp. 243-251
-
-
Lin, C.-W.1
Wang, Y.2
Challa, P.3
Epstein, D.L.4
Yuan, F.5
-
52
-
-
78649529307
-
Barrier analysis of periocular drug delivery to the posterior segment
-
Ranta VP, Mannermaa E, Lummepuro K et al. Barrier analysis of periocular drug delivery to the posterior segment. J. Control. Release 148(1) 42-48 (2010)
-
(2010)
J. Control. Release
, vol.148
, Issue.1
, pp. 42-48
-
-
Ranta, V.P.1
Mannermaa, E.2
Lummepuro, K.3
-
53
-
-
0242558882
-
In vivo determination of steric and electrostatic exclusion of albumin in rat skin and skeletal muscle
-
DOI 10.1113/jphysiol.2003.049379
-
Gyenge CC, Tenstad O, Wiig H. In vivo determination of steric and electrostatic exclusion of albumin in rat skin and skeletal muscle. J. Physiol. 552, 907-916 (2003) (Pubitemid 37428429)
-
(2003)
Journal of Physiology
, vol.552
, Issue.3
, pp. 907-916
-
-
Gyenge, C.C.1
Tenstad, O.2
Wiig, H.3
-
54
-
-
0347503515
-
Intersitial exluded volumes: The effect of charge
-
DOI 10.1113/jphysiol.2003.053595
-
Taylor AE, Parker JC. Intersitial exluded volumes: the effect of charge. J. Physiol. 553, 333 (2003) (Pubitemid 37527537)
-
(2003)
Journal of Physiology
, vol.553
, Issue.2
, pp. 333
-
-
Taylor, A.E.1
Parker, J.C.2
-
55
-
-
0037251511
-
Controlled delivery of the anti-VEGF aptamer EYE001 with poly(lactic-co-glycolic)acid microspheres
-
DOI 10.1167/iovs.01-1156
-
Carrasquillo KG, Ricker JA, Rigas IK, Miller JW, Gragoudas ES, Adamis AP. Controlled delivery of the anti-VEGF aptamer EYE001 with poly(lactic-co- glycolic)acid microspheres. Invest. Ophthalmol. Vis. Sci. 44, 290-299 (2003) (Pubitemid 36134287)
-
(2003)
Investigative Ophthalmology and Visual Science
, vol.44
, Issue.1
, pp. 290-299
-
-
Carrasquillo, K.G.1
Ricker, J.A.2
Rigas, I.K.3
Miller, J.W.4
Gragoudas, E.S.5
Adamis, A.P.6
-
56
-
-
0032575347
-
Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: Analysis of the binding site
-
DOI 10.1021/bi9802317
-
Alberdi E, Hyde CC, Becerra SP. Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: analysis of the binding site. Biochemistry 37, 10643-10652 (1998) (Pubitemid 28357865)
-
(1998)
Biochemistry
, vol.37
, Issue.30
, pp. 10643-10652
-
-
Alberdi, E.1
Hyde, C.C.2
Becerra, S.P.3
-
57
-
-
0025332848
-
Insulin and IGF-1 binding in chick sclera
-
Waldbillig RJ, Arnold DR, Fletcher RT, Chader GJ. Insulin and IGF-1 binding in chick sclera. Invest. Ophthalmol. Vis. Sci. 31, 1015-1022 (1990) (Pubitemid 20197623)
-
(1990)
Investigative Ophthalmology and Visual Science
, vol.31
, Issue.6
, pp. 1015-1022
-
-
Waldbillig, R.J.1
Arnold, D.R.2
Fletcher, R.T.3
Chader, G.J.4
-
58
-
-
77952787410
-
Macromolecular diffusion characteristics of ageing human bruchs membrane: Implications for age-related macular degeneration AMD exp
-
Hussain AA, Starita C, Hodgetts A, Marshall J. Macromolecular diffusion characteristics of ageing human Bruch's membrane: implications for age-related macular degeneration (AMD)Exp. Eye Res. 90, 703-710 (2010)
-
(2010)
Eye Res.
, vol.90
, pp. 703-710
-
-
Hussain, A.A.1
Starita, C.2
Hodgetts, A.3
Marshall, J.4
-
59
-
-
0013837411
-
Fine structure of the choriocapillaris and retinal capillaries
-
Bernstein MH, Hollenberg MJ. Fine structure of the choriocapillaris and retinal capillaries. Invest. Ophthalmol. Vis. Sci. 4, 1016-1025 (1965)
-
(1965)
Invest. Ophthalmol. Vis. Sci.
, vol.4
, pp. 1016-1025
-
-
Bernstein, M.H.1
Hollenberg, M.J.2
-
60
-
-
0030893690
-
Localization of the site of major resistance to fluid transport in Bruch's membrane
-
Starita C, Hussain AA, Patmore A, Marshall J. Localization of the site of major resistance to fluid transport in Bruch's membrane. Invest. Ophthalmol. Vis. Sci. 38, 762-767 (1997) (Pubitemid 27143147)
-
(1997)
Investigative Ophthalmology and Visual Science
, vol.38
, Issue.3
, pp. 762-767
-
-
Starita, C.1
Hussain, A.U.A.2
Patmore, A.3
Marshall, J.4
-
61
-
-
0034755091
-
The effect of age on the macromolecular permeability of human Bruch's membrane
-
Moore DJ, Clover GM. The effect of age on the macromolecular permeability of human Bruch's membrane. Invest. Ophthalmol. Vis. Sci. 42, 2970-2975 (2001) (Pubitemid 33035298)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.12
, pp. 2970-2975
-
-
Moore, D.J.1
Clover, G.M.2
-
62
-
-
13944264268
-
Permeability of retinal pigment epithelium: Effects of permeant molecular weight and lipophilicity
-
DOI 10.1167/iovs.04-1051
-
Pitkanen L, Ranta VP, Moilanen H, Urtti A. Permeability of retinal pigment epithelium: effects of permeant molecular weight and lipophilicity. Invest. Ophthalmol. Vis. Sci. 46, 641-646 (2005) (Pubitemid 40270347)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.2
, pp. 641-646
-
-
Pitkanen, L.1
Ranta, V.-P.2
Moilanen, H.3
Urtti, A.4
-
63
-
-
79954631233
-
Effect of formulation factors on the trans-scleral iontophoretic and post-iontophoretic transport of a 40 kDa dextran in-vitro
-
Pescina S, Padula C, Santi P, Nicoli S. Effect of formulation factors on the trans-scleral iontophoretic and post-iontophoretic transport of a 40 kDa dextran in-vitro. Eur. J. Pharm. Sci. 42, 503-508 (2011)
-
(2011)
Eur. J. Pharm. Sci.
, vol.42
, pp. 503-508
-
-
Pescina, S.1
Padula, C.2
Santi, P.3
Nicoli, S.4
-
64
-
-
77951464076
-
Delivery of celecoxib for treating diseases of the eye: Influence of pigment and diabetes
-
Amrite A, Pugazhenthi V, Cheruvu N, Kompella U. Delivery of celecoxib for treating diseases of the eye: influence of pigment and diabetes. Expert. Opin. Drug Deliv. 7, 631-645 (2010)
-
(2010)
Expert. Opin. Drug Deliv.
, vol.7
, pp. 631-645
-
-
Amrite, A.1
Pugazhenthi, V.2
Cheruvu, N.3
Kompella, U.4
-
66
-
-
34848825640
-
Binding of betaxolol, metoprolol and oligonucleotides to synthetic and bovine ocular melanin, and prediction of drug binding to melanin in human choroid-retinal pigment epithelium
-
DOI 10.1007/s11095-007-9342-0
-
Pitkanen L, Ranta VP, Moilanen H, Urtti A. Binding of betaxolol, metoprolol and oligonucleotides to synthetic and bovine ocular melanin, and prediction of drug binding to melanin in human choroid-retinal pigment epithelium. Pharm. Res. 24, 2063-2070 (2007) (Pubitemid 47493576)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.11
, pp. 2063-2070
-
-
Pitkanen, L.1
Ranta, V.-P.2
Moilanen, H.3
Urtti, A.4
-
67
-
-
77952090984
-
Bacterial melanin interacts with double-stranded DNA with high affinity and may inhibit cell metabolism in vivo
-
Geng J, Yuan P, Shao C et al. Bacterial melanin interacts with double-stranded DNA with high affinity and may inhibit cell metabolism in vivo. Arch. Microbiol. 192, 321-329 (2010)
-
(2010)
Arch. Microbiol.
, vol.192
, pp. 321-329
-
-
Geng, J.1
Yuan, P.2
Shao, C.3
-
68
-
-
0034685648
-
Melanin binds reversibly to thermostable DNA polymerase and inhibits its activity
-
DOI 10.1006/bbrc.2000.2716
-
Eckhart L, Bach J, Ban J, Tschachler E. Melanin binds reversibly to thermostable DNA polymerase and inhibits its activity. Biochem. Biophys. Res. Commun. 271, 726-730 (2000) (Pubitemid 30444696)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.271
, Issue.3
, pp. 726-730
-
-
Eckhart, L.1
Bach, J.2
Ban, J.3
Tschachler, E.4
-
69
-
-
77950023355
-
Episcleral clearance of sodium fluorescein from a bioerodible sub-tenons implant in the rat
-
Chan JE, Pridgen TA, Csaky KG. Episcleral clearance of sodium fluorescein from a bioerodible sub-tenon's implant in the rat. Exp. Eye Res. 90, 501-506 (2010)
-
(2010)
Exp. Eye Res.
, vol.90
, pp. 501-506
-
-
Chan, J.E.1
Pridgen, T.A.2
Csaky, K.G.3
-
70
-
-
31344468895
-
A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide
-
DOI 10.1016/j.exer.2005.08.007, PII S0014483505002484
-
Robinson MR, Lee SS, Kim H et al. A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide. Exp. Eye Res. 82, 479-487 (2006) (Pubitemid 43138962)
-
(2006)
Experimental Eye Research
, vol.82
, Issue.3
, pp. 479-487
-
-
Robinson, M.R.1
Lee, S.S.2
Kim, H.3
Kim, S.4
Lutz, R.J.5
Galban, C.6
Bungay, P.M.7
Yuan, P.8
Wang, N.S.9
Kim, J.10
Csaky, K.G.11
-
71
-
-
0016661107
-
Fracture faces of fenestrations and junctions of endothelial cells in human choroidal vessels
-
Spitznas M, Reale E. Fracture faces of fenestrations and junctions of endothelial cells in human choroidal vessels. Invest. Ophthalmol. Vis. Sci. 14, 98-107 (1975)
-
(1975)
Invest. Ophthalmol. Vis. Sci.
, vol.14
, pp. 98-107
-
-
Spitznas, M.1
Reale, E.2
-
72
-
-
77649329002
-
Sustained subconjunctival protein delivery using a thermosetting gel delivery system
-
Rieke ER, Amaral J, Becerra SP, Lutz RJ. Sustained subconjunctival protein delivery using a thermosetting gel delivery system. J. Ocul. Pharmacol. Ther. 26, 55-64 (2010)
-
(2010)
J. Ocul. Pharmacol. Ther.
, vol.26
, pp. 55-64
-
-
Rieke, E.R.1
Amaral, J.2
Becerra, S.P.3
Lutz, R.J.4
-
73
-
-
1942455881
-
In vitro model of the outer blood-retina barrier
-
DOI 10.1016/j.brainresprot.2003.12.002, PII S1385299X04000030
-
Steuer H, Jaworski A, Stoll D, Schlosshauer B. In vitro model of the outer blood-retina barrier. Brain Res. Brain Res. Protoc. 13, 26-36 (2004) (Pubitemid 38519596)
-
(2004)
Brain Research Protocols
, vol.13
, Issue.1
, pp. 26-36
-
-
Steuer, H.1
Jaworski, A.2
Stoll, D.3
Schlosshauer, B.4
-
74
-
-
20444392777
-
Cell culture models of the ocular barriers
-
DOI 10.1016/j.ejpb.2005.01.009, PII S0939641105000214
-
Hornof M, Toropainen E, Urtti A. Cell culture models of the ocular barriers. Eur. J. Pharm. Biopharm. 60, 207-225 (2005) (Pubitemid 40804562)
-
(2005)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.60
, Issue.2
, pp. 207-225
-
-
Hornof, M.1
Toropainen, E.2
Urtti, A.3
-
75
-
-
77953541928
-
Filter-cultured ARPE-19 cells as outer blood- retinal barrier model
-
Mannermaa E, Reinisalo M, Ranta VP et al. Filter-cultured ARPE-19 cells as outer blood- retinal barrier model. Eur. J. Pharm. Sci. 40, 289-296 (2010)
-
(2010)
Eur. J. Pharm. Sci.
, vol.40
, pp. 289-296
-
-
Mannermaa, E.1
Reinisalo, M.2
Ranta, V.P.3
-
76
-
-
67349274138
-
Efflux protein expression in human retinal pigment epithelium cell lines
-
Mannermaa E, Vellonen KS, Ryhanen T et al. Efflux protein expression in human retinal pigment epithelium cell lines. Pharm. Res. 26, 1785-1791 (2009)
-
(2009)
Pharm. Res.
, vol.26
, pp. 1785-1791
-
-
Mannermaa, E.1
Vellonen, K.S.2
Ryhanen, T.3
-
77
-
-
33751172725
-
Drug transport in corneal epithelium and blood- retina barrier: Emerging role of transporters in ocular pharmacokinetics
-
Mannermaa E, Vellonen KS, Urtti A. Drug transport in corneal epithelium and blood- retina barrier: emerging role of transporters in ocular pharmacokinetics. Adv. Drug Deliv. Rev. 58, 1136-1163 (2006)
-
(2006)
Adv. Drug Deliv. Rev.
, vol.58
, pp. 1136-1163
-
-
Mannermaa, E.1
Vellonen, K.S.2
Urtti, A.3
-
78
-
-
33644792954
-
Transscleral-RPE permeability of PEDF and ovalbumin proteins: Implications for subconjunctival protein delivery
-
DOI 10.1167/iovs.05-0492
-
Amaral J, Fariss RN, Campos MM et al. Transscleral-RPE permeability of PEDF and ovalbumin proteins: implications for subconjunctival protein delivery. Invest. Ophthalmol. Vis. Sci. 46, 4383-4392 (2005) (Pubitemid 44264530)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.12
, pp. 4383-4392
-
-
Amaral, J.1
Fariss, R.N.2
Campos, M.M.3
Robison Jr., W.G.4
Kim, H.5
Lutz, R.6
Becerra, S.P.7
-
79
-
-
33947432845
-
Protein transport to choroid and retina following periocular injection: Theoretical and experimental study
-
DOI 10.1007/s10439-006-9238-x
-
Mac Gabhann F, Demetriades AM, Deering T et al. Protein transport to choroid and retina following periocular injection: theoretical and experimental study. Ann. Biomed. Eng. 35, 615-630 (2007) (Pubitemid 46448166)
-
(2007)
Annals of Biomedical Engineering
, vol.35
, Issue.4
, pp. 615-630
-
-
Mac Gabhann, F.1
Demetriades, A.M.2
Deering, T.3
Packer, J.D.4
Shah, S.M.5
Duh, E.6
Campochiaro, P.A.7
Popel, A.S.8
-
80
-
-
0031592962
-
A culture model of development reveals multiple properties of RPE tight junctions
-
Ban Y, Rizzolo LJ. A culture model of development reveals multiple properties of RPE tight junctions. Mol. Vis. 3, 18 (1997)
-
(1997)
Mol. Vis.
, vol.3
, pp. 18
-
-
Ban, Y.1
Rizzolo, L.J.2
-
81
-
-
53149104782
-
Human transscleral albumin permeability and the effect of topographical location and donor age
-
Anderson OA, Jackson TL, Singh JK, Hussain AA, Marshall J. Human transscleral albumin permeability and the effect of topographical location and donor age. Invest. Ophthalmol. Vis. Sci. 49, 4041-4045 (2008)
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
, pp. 4041-4045
-
-
Anderson, O.A.1
Jackson, T.L.2
Singh, J.K.3
Hussain, A.A.4
Marshall, J.5
-
82
-
-
77951295070
-
Vitreoretinal disease in the coming decade
-
Chiang A, Haller JA. Vitreoretinal disease in the coming decade. Curr. Opin. Ophthalmol. 21, 197-202 (2010)
-
(2010)
Curr. Opin. Ophthalmol.
, vol.21
, pp. 197-202
-
-
Chiang, A.1
Haller, J.A.2
-
83
-
-
42249115543
-
Recent patents on ocular drug delivery systems
-
DOI 10.2174/187221108783331410
-
Conway BR. Recent patents on ocular drug delivery systems. Recent Pat. Drug Deliv. Formul. 2, 1-8 (2008) (Pubitemid 351546429)
-
(2008)
Recent Patents on Drug Delivery and Formulation
, vol.2
, Issue.1
, pp. 1-8
-
-
Conway, B.R.1
-
84
-
-
79955654103
-
An updated patent review on ocular drug delivery systems with potential for commercial viability
-
Srivastava R, Pathak K. An updated patent review on ocular drug delivery systems with potential for commercial viability. Recent Pat. Drug Deliv. Formul. 5, 146-162 (2011)
-
(2011)
Recent Pat. Drug Deliv. Formul.
, vol.5
, pp. 146-162
-
-
Srivastava, R.1
Pathak, K.2
-
85
-
-
78650582969
-
Applications of nanoparticles in ophthalmology
-
Diebold Y, Calonge M. Applications of nanoparticles in ophthalmology. Prog. Retin. Eye Res. 29, 596-609 (2010)
-
(2010)
Prog. Retin. Eye Res.
, vol.29
, pp. 596-609
-
-
Diebold, Y.1
Calonge, M.2
-
86
-
-
79953024995
-
Potential of liposomes for the intravitreal injection of therapeutic molecules
-
Bochot A, Lajavardi L, Camelo S et al. Potential of liposomes for the intravitreal injection of therapeutic molecules. Ann. Pharm. Fr. 69, 100-107 (2011)
-
(2011)
Ann. Pharm. Fr.
, vol.69
, pp. 100-107
-
-
Bochot, A.1
Lajavardi, L.2
Camelo, S.3
-
89
-
-
65749105937
-
Design and evaluation of a liposomal delivery system targeting the posterior segment of the eye
-
Hironaka K, Inokuchi Y, Tozuka Y, Shimazawa M, Hara H, Takeuchi H. Design and evaluation of a liposomal delivery system targeting the posterior segment of the eye. J. Control. Release 136, 247-253 (2009)
-
(2009)
J. Control. Release
, vol.136
, pp. 247-253
-
-
Hironaka, K.1
Inokuchi, Y.2
Tozuka, Y.3
Shimazawa, M.4
Hara, H.5
Takeuchi, H.6
-
90
-
-
40649113410
-
Subconjunctival topotecan in fibrin sealant in the treatment of transgenic murine retinoblastoma
-
Tsui JY, Dalgard C, Van Quill KR et al. Subconjunctival topotecan in fibrin sealant in the treatment of transgenic murine retinoblastoma. Invest. Ophthalmol. Vis. Sci. 49, 490-496 (2008)
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
, pp. 490-496
-
-
Tsui, J.Y.1
Dalgard, C.2
Van Quill, K.R.3
-
91
-
-
0036333401
-
Transscleral diffusion of carboplatin: An in vitro and in vivo study
-
Simpson AE, Gilbert JA, Rudnick DE et al. Transscleral diffusion of carboplatin: an in vitro and in vivo study. Arch. Ophthalmol. 120, 1069-1074 (2002) (Pubitemid 34856075)
-
(2002)
Archives of Ophthalmology
, vol.120
, Issue.8
, pp. 1069-1074
-
-
Simpson, A.E.1
Gilbert, J.A.2
Rudnick, D.E.3
Geroski, D.H.4
Aaberg Jr., T.M.5
Edelhauser, H.F.6
-
92
-
-
20144377752
-
Subconjunctival carboplatin in fibrin sealant in the treatment of transgenic murine retinoblastoma
-
DOI 10.1016/j.ophtha.2004.11.060, PII S0161642005001132
-
Van Quill KR, Dioguardi PK, Tong CT et al. Subconjunctival carboplatin in fibrin sealant in the treatment of transgenic murine retinoblastoma. Ophthalmology 112, 1151-1158 (2005) (Pubitemid 40797475)
-
(2005)
Ophthalmology
, vol.112
, Issue.6
, pp. 1151-1158
-
-
Van Quill, K.R.1
Dioguardi, P.K.2
Tong, C.T.3
Gilbert, J.A.4
Aaberg Jr., T.M.5
Grossniklaus, H.E.6
Edelhauser, H.F.7
O'Brien, J.M.8
-
93
-
-
28644432836
-
Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration
-
DOI 10.1211/jpp.57.12.0005
-
Amrite AC, Kompella UB. Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration. J. Pharm. Pharmacol. 57, 1555-1563 (2005) (Pubitemid 41752269)
-
(2005)
Journal of Pharmacy and Pharmacology
, vol.57
, Issue.12
, pp. 1555-1563
-
-
Amrite, A.C.1
Kompella, U.B.2
-
94
-
-
63049131601
-
Thermoresponsive hydrogels as a new ocular drug delivery platform to the posterior segment of the eye
-
discussion 213-214
-
Kang Derwent JJ, Mieler WF. Thermoresponsive hydrogels as a new ocular drug delivery platform to the posterior segment of the eye. Trans. Am. Ophthalmol. Soc. 106, 206-213; discussion 213-214 (2008)
-
(2008)
Trans. Am. Ophthalmol. Soc.
, vol.106
, pp. 206-213
-
-
Kang Derwent, J.J.1
Mieler, W.F.2
-
95
-
-
70349290518
-
Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina
-
Misra GP, Singh RS, Aleman TS, Jacobson SG, Gardner TW, Lowe TL. Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina. Biomaterials 30, 6541-6547 (2009)
-
(2009)
Biomaterials
, vol.30
, pp. 6541-6547
-
-
Misra, G.P.1
Singh, R.S.2
Aleman, T.S.3
Jacobson, S.G.4
Gardner, T.W.5
Lowe, T.L.6
-
96
-
-
0034114629
-
Transscleral delivery of bioactive protein to the choroid and retina
-
Ambati J, Gragoudas ES, Miller JW et al. Transscleral delivery of bioactive protein to the choroid and retina. Invest. Ophthalmol. Vis. Sci. 41, 1186-1191 (2000) (Pubitemid 30187559)
-
(2000)
Investigative Ophthalmology and Visual Science
, vol.41
, Issue.5
, pp. 1186-1191
-
-
Ambati, J.1
Gragoudas, E.S.2
Miller, J.W.3
You, T.T.4
Miyamoto, K.5
Delori, F.C.6
Adamis, A.P.7
-
97
-
-
78650988630
-
A scalable controlled-release device for transscleral drug delivery to the retina
-
Kawashima T, Nagai N, Kaji H et al. A scalable controlled-release device for transscleral drug delivery to the retina Biomaterials 32, 1950-1956 (2011)
-
(2011)
Biomaterials
, vol.32
, pp. 1950-1956
-
-
Kawashima, T.1
Nagai, N.2
Kaji, H.3
-
99
-
-
35148894469
-
Coated microneedles for drug delivery to the eye
-
DOI 10.1167/iovs.07-0066
-
Jiang J, Gill HS, Ghate D et al. Coated microneedles for drug delivery to the eye. Invest. Ophthalmol. Vis. Sci. 48, 4038-4043 (2007) (Pubitemid 351261027)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.9
, pp. 4038-4043
-
-
Jiang, J.1
Gill, H.S.2
Ghate, D.3
McCarey, B.E.4
Patel, S.R.5
Edelhauser, H.F.6
Prausnitz, M.R.7
-
100
-
-
58549106105
-
Intrascleral drug delivery to the eye using hollow microneedles
-
Jiang J, Moore JS, Edelhauser HF, Prausnitz MR. Intrascleral drug delivery to the eye using hollow microneedles. Pharm. Res. 26, 395-403 (2009)
-
(2009)
Pharm. Res.
, vol.26
, pp. 395-403
-
-
Jiang, J.1
Moore, J.S.2
Edelhauser, H.F.3
Prausnitz, M.R.4
-
101
-
-
78651245667
-
Suprachoroidal drug delivery to the back of the eye using hollow microneedles
-
Patel SR, Lin AS, Edelhauser HF, Prausnitz MR. Suprachoroidal drug delivery to the back of the eye using hollow microneedles. Pharm. Res. 28, 166-176 (2011)
-
(2011)
Pharm. Res.
, vol.28
, pp. 166-176
-
-
Patel, S.R.1
Lin, A.S.2
Edelhauser, H.F.3
Prausnitz, M.R.4
-
102
-
-
0034080281
-
Low-frequency sonophoresis: A noninvasive method of drug delivery and diagnostics
-
DOI 10.1021/bp000024+
-
Mitragotri S, Kost J. Low-frequency sonophoresis: a noninvasive method of drug delivery and diagnostics. Biotechnol. Prog. 16, 488-492 (2000) (Pubitemid 30369022)
-
(2000)
Biotechnology Progress
, vol.16
, Issue.3
, pp. 488-492
-
-
Mitragotri, S.1
Kost, J.2
-
103
-
-
3242765953
-
Ultrasound and transdermal drug delivery
-
DOI 10.1016/S1359-6446(04)03170-8, PII S1359644604031708
-
Lavon I, Kost J. Ultrasound and transdermal drug delivery. Drug Discov. Today 9, 670-676 (2004). (Pubitemid 38981721)
-
(2004)
Drug Discovery Today
, vol.9
, Issue.15
, pp. 670-676
-
-
Lavon, I.1
Kost, J.2
-
104
-
-
78049261849
-
Ultrasound-enhanced intrascleral delivery of protein
-
Cheung AC, Yu Y, Tay D, Wong HS, Ellis-Behnke R, Chau Y. Ultrasound-enhanced intrascleral delivery of protein. Int. J. Pharm. 401, 16-24 (2010)
-
(2010)
Int. J. Pharm.
, vol.401
, pp. 16-24
-
-
Cheung, A.C.1
Yu, Y.2
Tay, D.3
Wong, H.S.4
Ellis-Behnke, R.5
Chau, Y.6
-
105
-
-
0031822972
-
Iontophoretic permselectivity of mammalian skin: Characterization of hairless mouse and porcine membrane models
-
DOI 10.1023/A:1011909623019
-
Luzardo-Alvarez A, Rodriguez-Fernandez M, Blanco-Mendez J, Guy RH, Delgado-Charro MB. Iontophoretic permselectivity of mammalian skin: characterization of hairless mouse and porcine membrane models. Pharm. Res. 15, 984-987 (1998) (Pubitemid 28356911)
-
(1998)
Pharmaceutical Research
, vol.15
, Issue.7
, pp. 984-987
-
-
Luzardo-Alvarez, A.1
Rodriguez-Fernandez, M.2
Blanco-Mendez, J.3
Guy, R.H.4
Delgado-Charro, M.B.5
-
107
-
-
0038303190
-
Tolerance of ocular iontophoresis in healthy volunteers
-
Parkinson TM, Ferguson E, Febbraro S, Bakhtyari A, King M, Mundasad M. Tolerance of ocular iontophoresis in healthy volunteers. J. Ocul. Pharmacol. Ther. 19, 145-151 (2003) (Pubitemid 36539140)
-
(2003)
Journal of Ocular Pharmacology and Therapeutics
, vol.19
, Issue.2
, pp. 145-151
-
-
Parkinson, T.M.1
Ferguson, E.2
Febbraro, S.3
Bakhtyari, A.4
King, M.5
Mundasad, M.6
-
108
-
-
0036912669
-
In vivo transscleral iontophoresis of amikacin to rabbit eyes
-
Vollmer DL, Szlek MA, Kolb K, Lloyd LB, Parkinson TM. In vivo transscleral iontophoresis of amikacin to rabbit eyes. J. Ocul. Pharmacol. Ther. 18, 549-558 (2002) (Pubitemid 36020256)
-
(2002)
Journal of Ocular Pharmacology and Therapeutics
, vol.18
, Issue.6
, pp. 549-558
-
-
Vollmer, D.L.1
Szlek, M.A.2
Kolb, K.3
Lloyd, L.B.4
Parkinson, T.M.5
-
109
-
-
44049088856
-
In vitro and in vivo evaluation of carboplatin delivery to the eye using hydrogel-iontophoresis
-
Eljarrat-Binstock E, Domb AJ, Orucov F, Dagan A, Frucht-Pery J, Pe'er J. In vitro and in vivo evaluation of carboplatin delivery to the eye using hydrogel-iontophoresis. Curr. Eye Res. 33, 269-275 (2008)
-
(2008)
Curr. Eye Res.
, vol.33
, pp. 269-275
-
-
Eljarrat-Binstock, E.1
Domb, A.J.2
Orucov, F.3
Dagan, A.4
Frucht-Pery, J.5
Peer, J.6
-
110
-
-
34548620530
-
Methotrexate delivery to the eye using transscleral hydrogel iontophoresis
-
DOI 10.1080/02713680701528674, PII 781950932
-
Eljarrat-Binstock E, Domb AJ, Orucov F, Frucht-Pery J, Pe'er J. Methotrexate delivery to the eye using transscleral hydrogel iontophoresis. Curr. Eye Res. 32, 639-646 (2007) (Pubitemid 47400678)
-
(2007)
Current Eye Research
, vol.32
, Issue.7-8
, pp. 639-646
-
-
Eljarrat-Binstock, E.1
Domb, A.J.2
Orucov, F.3
Frucht-Pery, J.4
Pe'er, J.5
-
111
-
-
77957019192
-
Trans-scleral iontophoretic delivery of low molecular weight therapeutics
-
Gungor S, Delgado-Charro MB, Ruiz-Perez B et al. Trans-scleral iontophoretic delivery of low molecular weight therapeutics. J. Control. Release 147, 225-231 (2010)
-
(2010)
J. Control. Release
, vol.147
, pp. 225-231
-
-
Gungor, S.1
Delgado-Charro, M.B.2
Ruiz-Perez, B.3
-
112
-
-
0036346995
-
Transscleral Coulomb-controlled iontophoresis of methylprednisolone into the rabbit eye: Influence of duration of treatment, current intensity and drug concentration on ocular tissue and fluid levels
-
DOI 10.1006/exer.2001.1098
-
Behar-Cohen FF, El Aouni A et al. Transscleral Coulomb-controlled iontophoresis of methylprednisolone into the rabbit eye: influence of duration of treatment, current intensity and drug concentration on ocular tissue and fluid levels. Exp. Eye Res. 74, 51-59 (2002) (Pubitemid 34948265)
-
(2002)
Experimental Eye Research
, vol.74
, Issue.1
, pp. 51-59
-
-
Behar-Cohen, F.F.1
El Aouni, A.2
Gautier, S.3
David, G.4
Davis, J.5
Chapon, P.6
Parel, J.M.7
-
113
-
-
0036786633
-
Ocular aspirin distribution: A comparison of intravenous topical and coulomb-controlled iontophoresis administration
-
Voigt M, Kralinger M, Kieselbach G et al. Ocular aspirin distribution: a comparison of intravenous, topical and Coulomb-controlled iontophoresis administration. Invest. Ophthalmol. Vis. Sci. 43, 3299-3306 (2002)
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 3299-3306
-
-
Voigt, M.1
Kralinger, M.2
Kieselbach, G.3
-
114
-
-
59349088579
-
In vitro transscleral iontophoresis of high molecular weight neutral compounds
-
Nicoli S, Ferrari G, Quarta M, Macaluso C, Santi P. In vitro transscleral iontophoresis of high molecular weight neutral compounds. Eur. J. Pharm. Sci. 36, 486-492 (2009)
-
(2009)
Eur. J. Pharm. Sci.
, vol.36
, pp. 486-492
-
-
Nicoli, S.1
Ferrari, G.2
Quarta, M.3
Macaluso, C.4
Santi, P.5
-
115
-
-
76549113537
-
Iontophoretic transport of charged macromolecules across human sclera
-
Chopra P, Hao J, Li SK. Iontophoretic transport of charged macromolecules across human sclera. Int. J. Pharm. 388, 107-113 (2010)
-
(2010)
Int. J. Pharm.
, vol.388
, pp. 107-113
-
-
Chopra, P.1
Hao, J.2
Li, S.K.3
-
116
-
-
77955242157
-
In vitro permeation of bevacizumab through human sclera: Effect of iontophoresis application
-
Pescina S, Ferrari G, Govoni P, Macaluso C et al. In vitro permeation of bevacizumab through human sclera: effect of iontophoresis application. J. Pharm. Pharmacol. 62, 1189-1194 (2010)
-
(2010)
J. Pharm. Pharmacol.
, vol.62
, pp. 1189-1194
-
-
Pescina, S.1
Ferrari, G.2
Govoni, P.3
Macaluso, C.4
-
117
-
-
0346039142
-
Delivery of several forms of DNA, DNA-RNA hybrids, and dyes across human sclera by electrical fields
-
Davies JB, Ciavatta VT, Boatright JH, Nickerson JM. Delivery of several forms of DNA, DNA-RNA hybrids, and dyes across human sclera by electrical fields. Mol. Vis. 15, 569-578 (2003) (Pubitemid 38097624)
-
(2003)
Molecular Vision
, vol.9
, pp. 569-578
-
-
Davies, J.B.1
Ciavatta, V.T.2
Boatright, J.H.3
Nickerson, J.M.4
-
118
-
-
0035191885
-
Induction of gene into the rabbit eye by iontophoresis: Preliminary report
-
DOI 10.1016/S0021-5155(00)00291-4, PII S0021515500002914
-
Asahara T, Shinomiya K, Naito T, Shiota H. Induction of gene into the rabbit eye by iontophoresis: preliminary report. Jpn J. Ophthalmol. 45, 31-39 (2001) (Pubitemid 32015891)
-
(2001)
Japanese Journal of Ophthalmology
, vol.45
, Issue.1
, pp. 31-39
-
-
Asahara, T.1
Shinomiya, K.2
Naito, T.3
Shiota, H.4
-
119
-
-
0036069080
-
Down-regulation of NOSII gene expression by iontophoresis of anti-sense oligonucleotide in endotoxin-induced uveitis
-
DOI 10.1016/S0006-291X(02)00656-3, PII S0006291X02006563
-
Voigt M, de Kozak Y, Halhal M, Courtois Y, Behar-Cohen F. Down-regulation of NOSII gene expression by iontophoresis of anti-sense oligonucleotide in endotoxin-induced uveitis. Biochem. Biophys. Res. Commun. 295, 336-341 (2002) (Pubitemid 34785839)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.295
, Issue.2
, pp. 336-341
-
-
Voigt, M.1
De Kozak, Y.2
Halhal, M.3
Courtois, Y.4
Behar-Cohen, F.5
-
120
-
-
50849117810
-
Non-invasive gene transfer by iontophoresis for therapy of an inherited retinal degeneration
-
Souied EH, Reid SNM, Piri NI, Lerner LE, Nusinowitz S, Farber DB. Non-invasive gene transfer by iontophoresis for therapy of an inherited retinal degeneration. Exp. Eye Res. 87, 168-175 (2008)
-
(2008)
Exp. Eye Res.
, vol.87
, pp. 168-175
-
-
Souied, E.H.1
Reid, S.N.M.2
Piri, N.I.3
Lerner, L.E.4
Nusinowitz, S.5
Farber, D.B.6
-
121
-
-
61549127583
-
Transscleral iontophoretic and intravitreal delivery of a macromolecule: Study of ocular distribution in vivo and postmortem with MRI
-
Molokhia SA, Jeong EK, Higuchi WI, Li SK. Transscleral iontophoretic and intravitreal delivery of a macromolecule: study of ocular distribution in vivo and postmortem with MRI. Exp. Eye Res. 88, 418-425 (2009)
-
(2009)
Exp. Eye Res.
, vol.88
, pp. 418-425
-
-
Molokhia, S.A.1
Jeong, E.K.2
Higuchi, W.I.3
Li, S.K.4
-
122
-
-
38749087775
-
Modeling of corneal and retinal pharmacokinetics after periocular drug administration
-
Amrite AC, Edelhauser HF, Kompella UB. Modeling of corneal and retinal pharmacokinetics after periocular drug administration. Invest. Ophthalmol. Vis. Sci. 49, 320-332 (2008)
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
, pp. 320-332
-
-
Amrite, A.C.1
Edelhauser, H.F.2
Kompella, U.B.3
-
123
-
-
53849107134
-
Computer modeling of drug delivery to the posterior eye: Effect of active transport and loss to choroidal blood flow
-
Balachandran RK, Barocas VH. Computer modeling of drug delivery to the posterior eye: effect of active transport and loss to choroidal blood flow. Pharm. Res. 25, 2685-2696 (2008)
-
(2008)
Pharm. Res.
, vol.25
, pp. 2685-2696
-
-
Balachandran, R.K.1
Barocas, V.H.2
-
124
-
-
1042277993
-
Drug Delivery to the Posterior Segment of the Eye II: Development and Validation of a Simple Pharmacokinetic Model for Subconjunctival Injection
-
Lee TW, Robinson JR. Drug delivery to the posterior segment of the eye II: development and validation of a simple pharmacokinetic model for subconjunctival injection. J. Ocul. Pharmacol. Ther. 20, 43-53 (2004) (Pubitemid 38199331)
-
(2004)
Journal of Ocular Pharmacology and Therapeutics
, vol.20
, Issue.1
, pp. 43-53
-
-
Lee, T.W.-Y.1
Robinson, J.R.2
-
125
-
-
61749095866
-
Drug delivery to the posterior segment of the eye IV: Theoretical formulation of a drug delivery system for subconjunctival injection
-
Lee TW, Robinson JR. Drug delivery to the posterior segment of the eye IV: theoretical formulation of a drug delivery system for subconjunctival injection. J. Ocul. Pharmacol. Ther. 25, 29-37 (2009)
-
(2009)
J. Ocul. Pharmacol. Ther.
, vol.25
, pp. 29-37
-
-
Lee, T.W.1
Robinson, J.R.2
-
126
-
-
33947432845
-
Protein transport to choroid and retina following periocular injection: Theoretical and experimental study
-
DOI 10.1007/s10439-006-9238-x
-
Mac Gabhann F, Demetriades AM, Deering T et al. Protein transport to choroid and retina following periocular injection: theoretical and experimental study. Ann. Biomed. Eng. 35, 615-630 (2007) (Pubitemid 46448166)
-
(2007)
Annals of Biomedical Engineering
, vol.35
, Issue.4
, pp. 615-630
-
-
Mac Gabhann, F.1
Demetriades, A.M.2
Deering, T.3
Packer, J.D.4
Shah, S.M.5
Duh, E.6
Campochiaro, P.A.7
Popel, A.S.8
-
127
-
-
0033812535
-
Vitreal elimination kinetics of large molecular weight FITC-labeled dextrans in albino rabbits using a novel microsampling technique
-
Dias CS, Mitra AK. Vitreal elimination kinetics of large molecular weight FITC-labeled dextrans in albino rabbits using a novel microsampling technique. J. Pharm. Sci. 89, 572-578 (2000)
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 572-578
-
-
Dias, C.S.1
Mitra, A.K.2
-
128
-
-
63949084933
-
Prediction of vitreal half-life based on drug physicochemical properties: Quantitative structure-pharmacokinetic relationships QSPKR
-
Durairaj C, Shah JC, Senapati S, Kompella UB. Prediction of vitreal half-life based on drug physicochemical properties: quantitative structure-pharmacokinetic relationships (QSPKR)Pharm. Res. 26, 1236-1260 (2009)
-
(2009)
Pharm. Res.
, vol.26
, pp. 1236-1260
-
-
Durairaj, C.1
Shah, J.C.2
Senapati, S.3
Kompella, U.B.4
-
129
-
-
32944479596
-
The influence of intraocular pressure on the transscleral diffusion of high-molecular-weight compounds
-
DOI 10.1167/iovs.04-1414
-
Cruysberg LP, Nuijts RM, Geroski DH, Gilbert JA, Hendrikse F, Edelhauser HF. The influence of intraocular pressure on the transscleral diffusion of high-molecular-weight compounds. Invest. Ophthalmol. Vis. Sci. 46, 3790-3794 (2005) (Pubitemid 44264687)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.10
, pp. 3790-3794
-
-
Cruysberg, L.P.J.1
Nuijts, R.M.M.A.2
Geroski, D.H.3
Gilbert, J.A.4
Hendrikse, F.5
Edelhauser, H.F.6
-
130
-
-
1842474949
-
Scleral Permeability of a Small, Single-Stranded Oligonucleotide
-
DOI 10.1089/108076804773710830
-
Shuler RK Jr, Dioguardi PK, Henjy C, Nickerson JM, Cruysberg LP, Edelhauser HF. Scleral permeability of a small, single-stranded oligonucleotide. J. Ocul. Pharmacol. Ther. 20, 159-168 (2004) (Pubitemid 38456589)
-
(2004)
Journal of Ocular Pharmacology and Therapeutics
, vol.20
, Issue.2
, pp. 159-168
-
-
Shuler Jr., R.K.1
Dioguardi, P.K.2
Henjy, C.3
Nickerson, J.M.4
Cruysberg, L.P.J.5
Edelhauser, H.F.6
-
132
-
-
0023553501
-
Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea
-
Ahmed I, Gokhale RD, Shah MV, Patton TF. Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea. J. Pharm. Sci. 76, 583-586 (1987). (Pubitemid 18026341)
-
(1987)
Journal of Pharmaceutical Sciences
, vol.76
, Issue.8
, pp. 583-586
-
-
Ahmed, I.1
Gokhale, R.D.2
Shah, M.V.3
Patton Th., F.4
|