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Volumn 15, Issue 7-8, 2010, Pages 272-282

Delivery of anti-angiogenic molecular therapies for retinal disease

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ADENOVIRUS VECTOR; AFLIBERCEPT; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; BROMFENAC; DEXAMETHASONE; DOXYCYCLINE; ECALLANTIDE; EVEROLIMUS; FLUOCINOLONE; INFLIXIMAB; JSM 6427; MECAMYLAMINE; MP 0112; NEPAFENAC; OCTREOTIDE; PARVOVIRUS VECTOR; PAZOPANIB; PEGAPTANIB; PIGMENT EPITHELIUM DERIVED FACTOR INHIBITOR; PYRROLIDINE DERIVATIVE; RANIBIZUMAB; RAPAMYCIN; RUBOXISTAURIN; TRIAMCINOLONE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN INHIBITOR; VATALANIB; VOLOCIXIMAB;

EID: 77950924888     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2010.02.004     Document Type: Review
Times cited : (30)

References (78)
  • 2
    • 0029803235 scopus 로고    scopus 로고
    • The cause-specific prevalence of visual impairment in an urban population. The Baltimore Eye Survey
    • Rahmani B., et al. The cause-specific prevalence of visual impairment in an urban population. The Baltimore Eye Survey. Ophthalmology 1996, 103:1721-1726.
    • (1996) Ophthalmology , vol.103 , pp. 1721-1726
    • Rahmani, B.1
  • 3
    • 0029143382 scopus 로고
    • Preventative ophthalmology. Age-related macular degeneration
    • Bressler N.M., Bressler S.B. Preventative ophthalmology. Age-related macular degeneration. Ophthalmology 1995, 102:1206-1211.
    • (1995) Ophthalmology , vol.102 , pp. 1206-1211
    • Bressler, N.M.1    Bressler, S.B.2
  • 4
    • 39149121847 scopus 로고    scopus 로고
    • Current and future ophthalmic drug delivery systems. A shift to the posterior segment
    • Del Amo E.M., Urtti A. Current and future ophthalmic drug delivery systems. A shift to the posterior segment. Drug Discov. Today 2008, 13:135-143.
    • (2008) Drug Discov. Today , vol.13 , pp. 135-143
    • Del Amo, E.M.1    Urtti, A.2
  • 5
    • 0029946393 scopus 로고    scopus 로고
    • Differential effects of angiostatic steroids and dexamethasone on angiogenesis and cytokine levels in rat sponge implants
    • Hori Y., et al. Differential effects of angiostatic steroids and dexamethasone on angiogenesis and cytokine levels in rat sponge implants. Br. J. Pharmacol. 1996, 118:1584-1591.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1584-1591
    • Hori, Y.1
  • 6
    • 11144239923 scopus 로고    scopus 로고
    • Pegaptanib for neovascular age-related macular degeneration
    • Gragoudas E.S., et al. Pegaptanib for neovascular age-related macular degeneration. N. Engl. J. Med. 2004, 351:2805-2816.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2805-2816
    • Gragoudas, E.S.1
  • 7
    • 32844458094 scopus 로고    scopus 로고
    • Pegaptanib sodium for the treatment of neovascular age-related macular degeneration: a review
    • Kourlas H., Schiller D.S. Pegaptanib sodium for the treatment of neovascular age-related macular degeneration: a review. Clin. Ther. 2006, 28:36-44.
    • (2006) Clin. Ther. , vol.28 , pp. 36-44
    • Kourlas, H.1    Schiller, D.S.2
  • 8
    • 0032493654 scopus 로고    scopus 로고
    • 2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
    • Ruckman J., et al. 2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J. Biol. Chem. 1998, 273:20556-20567.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20556-20567
    • Ruckman, J.1
  • 9
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age-related macular degeneration
    • Rosenfeld P.J., et al. Ranibizumab for neovascular age-related macular degeneration. N. Engl. J. Med. 2006, 355:1419-1431.
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1419-1431
    • Rosenfeld, P.J.1
  • 10
    • 33749451356 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin for neovascular age-related macular degeneration
    • Brown D.M., et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N. Engl. J. Med. 2006, 355:1432-1444.
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1432-1444
    • Brown, D.M.1
  • 11
    • 77950929456 scopus 로고    scopus 로고
    • The Royal College of Ophthalmologists Guidelines for Ranibizumab - the Clinician's Guide to commencing, continuing and discontinuing treatment ()
    • The Royal College of Ophthalmologists (2008) Guidelines for Ranibizumab - the Clinician's Guide to commencing, continuing and discontinuing treatment (). http://www.rcophth.ac.uk/about/publications.
    • (2008)
  • 12
    • 36549039554 scopus 로고    scopus 로고
    • Pharmacokinetics of intravitreal ranibizumab (Lucentis)
    • Bakri S.J., et al. Pharmacokinetics of intravitreal ranibizumab (Lucentis). Ophthalmology 2007, 114:2179-2182.
    • (2007) Ophthalmology , vol.114 , pp. 2179-2182
    • Bakri, S.J.1
  • 13
    • 34547657584 scopus 로고    scopus 로고
    • Vascular endothelial growth factor Trap in non small cell lung cancer
    • Riely G.J., Miller V.A. Vascular endothelial growth factor Trap in non small cell lung cancer. Clin. Cancer Res. 2007, 13:s4623-s4627.
    • (2007) Clin. Cancer Res. , vol.13
    • Riely, G.J.1    Miller, V.A.2
  • 14
    • 0037143764 scopus 로고    scopus 로고
    • VEGF-Trap: a VEGF blocker with potent antitumor effects
    • Holash J., et al. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:11393-11398.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 11393-11398
    • Holash, J.1
  • 15
    • 33747874091 scopus 로고    scopus 로고
    • A phase I trial of an IV-administered vascular endothelial growth factor trap for treatment in patients with choroidal neovascularization due to age-related macular degeneration
    • 1522.e1-1522.e14
    • Nguyen Q.D., et al. A phase I trial of an IV-administered vascular endothelial growth factor trap for treatment in patients with choroidal neovascularization due to age-related macular degeneration. Ophthalmology 2006, 113. 1522.e1-1522.e14.
    • (2006) Ophthalmology , vol.113
    • Nguyen, Q.D.1
  • 16
    • 0034031474 scopus 로고    scopus 로고
    • Diffusion of high molecular weight compounds through sclera
    • Ambati J., et al. Diffusion of high molecular weight compounds through sclera. Invest. Ophthalmol. Vis. Sci. 2000, 41:1181-1185.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 1181-1185
    • Ambati, J.1
  • 17
    • 0025775370 scopus 로고
    • Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with corneal penetration
    • Wang W., et al. Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with corneal penetration. Curr. Eye Res. 1991, 10:571-579.
    • (1991) Curr. Eye Res. , vol.10 , pp. 571-579
    • Wang, W.1
  • 18
    • 0034821034 scopus 로고    scopus 로고
    • Review: practical issues in intravitreal drug delivery
    • Maurice D. Review: practical issues in intravitreal drug delivery. J. Ocul. Pharmacol. Ther. 2001, 17:393-401.
    • (2001) J. Ocul. Pharmacol. Ther. , vol.17 , pp. 393-401
    • Maurice, D.1
  • 19
    • 0344074584 scopus 로고    scopus 로고
    • Pharmacokinetics of sparfloxacin in the serum and vitreous humor of rabbits: physicochemical properties that regulate penetration of quinolone antimicrobials
    • Liu W., et al. Pharmacokinetics of sparfloxacin in the serum and vitreous humor of rabbits: physicochemical properties that regulate penetration of quinolone antimicrobials. Antimicrob. Agents Chemother. 1998, 42:1417-1423.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 1417-1423
    • Liu, W.1
  • 20
    • 33846428067 scopus 로고    scopus 로고
    • Intravitreal VEGF-inhibitors: is Avastin a generic substitute for Lucentis?
    • la Cour M. Intravitreal VEGF-inhibitors: is Avastin a generic substitute for Lucentis?. Acta Ophthalmol. Scand. 2007, 85:2-4.
    • (2007) Acta Ophthalmol. Scand. , vol.85 , pp. 2-4
    • la Cour, M.1
  • 21
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta L.G., et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res. 1997, 57:4593-4599.
    • (1997) Cancer Res. , vol.57 , pp. 4593-4599
    • Presta, L.G.1
  • 22
    • 43649083100 scopus 로고    scopus 로고
    • Predicted biological activity of intravitreal VEGF Trap
    • Stewart M.W., Rosenfeld P.J. Predicted biological activity of intravitreal VEGF Trap. Br. J. Ophthalmol. 2008, 92:667-668.
    • (2008) Br. J. Ophthalmol. , vol.92 , pp. 667-668
    • Stewart, M.W.1    Rosenfeld, P.J.2
  • 23
    • 3042763334 scopus 로고    scopus 로고
    • Ocular pharmacokinetics of fluocinolone acetonide after Retisert intravitreal implantation in rabbits over a 1-year period
    • Driot J.Y., et al. Ocular pharmacokinetics of fluocinolone acetonide after Retisert intravitreal implantation in rabbits over a 1-year period. J. Ocul. Pharmacol. Ther. 2004, 20:269-275.
    • (2004) J. Ocul. Pharmacol. Ther. , vol.20 , pp. 269-275
    • Driot, J.Y.1
  • 24
    • 33751268869 scopus 로고    scopus 로고
    • Intraocular implants for extended drug delivery: therapeutic applications
    • Bourges J.L., et al. Intraocular implants for extended drug delivery: therapeutic applications. Adv. Drug Deliv. Rev. 2006, 58:1182-1202.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 1182-1202
    • Bourges, J.L.1
  • 25
    • 58149274997 scopus 로고    scopus 로고
    • Fluocinolone acetonide intravitreal implant to treat diabetic macular edema: 3-year results of a multi-center clinical trial (Abstract)
    • Pearson P., et al. Fluocinolone acetonide intravitreal implant to treat diabetic macular edema: 3-year results of a multi-center clinical trial (Abstract). Invest. Ophthalmol. Vis. Sci. 2006, 47:5442.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 5442
    • Pearson, P.1
  • 26
    • 0141793765 scopus 로고    scopus 로고
    • Endophthalmitis after ganciclovir implant in patients with AIDS and cytomegalovirus retinitis
    • Shane T.S., Martin D.F. Endophthalmitis after ganciclovir implant in patients with AIDS and cytomegalovirus retinitis. Am. J. Ophthalmol. 2003, 136:649-654.
    • (2003) Am. J. Ophthalmol. , vol.136 , pp. 649-654
    • Shane, T.S.1    Martin, D.F.2
  • 27
    • 1242319493 scopus 로고    scopus 로고
    • Complications of ganciclovir implant surgery in patients with cytomegalovirus retinitis: the Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial
    • Dunn J.P., et al. Complications of ganciclovir implant surgery in patients with cytomegalovirus retinitis: the Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial. Retina 2004, 24:41-50.
    • (2004) Retina , vol.24 , pp. 41-50
    • Dunn, J.P.1
  • 28
    • 84855470958 scopus 로고    scopus 로고
    • Biodegradable systems
    • Informa Healthcare, G.J. Jaffe (Ed.)
    • Kimura H., Ogura Y. Biodegradable systems. Intraocular Drug Delivery 2006, 175-192. Informa Healthcare. 1st ed. G.J. Jaffe (Ed.).
    • (2006) Intraocular Drug Delivery , pp. 175-192
    • Kimura, H.1    Ogura, Y.2
  • 29
    • 0034632944 scopus 로고    scopus 로고
    • Long-term sustained release of ganciclovir from biodegradable scleral implant for the treatment of cytomegalovirus retinitis
    • Kunou N., et al. Long-term sustained release of ganciclovir from biodegradable scleral implant for the treatment of cytomegalovirus retinitis. J. Control. Release 2000, 68:263-271.
    • (2000) J. Control. Release , vol.68 , pp. 263-271
    • Kunou, N.1
  • 30
    • 34247215173 scopus 로고    scopus 로고
    • Drug delivery methods for posterior segment disease
    • Hsu J. Drug delivery methods for posterior segment disease. Curr. Opin. Ophthalmol. 2007, 18:235-239.
    • (2007) Curr. Opin. Ophthalmol. , vol.18 , pp. 235-239
    • Hsu, J.1
  • 31
    • 0026669865 scopus 로고
    • Biodegradable microspheres containing adriamycin in the treatment of proliferative vitreoretinopathy
    • Moritera T., et al. Biodegradable microspheres containing adriamycin in the treatment of proliferative vitreoretinopathy. Invest. Ophthalmol. Vis. Sci. 1992, 33:3125-3130.
    • (1992) Invest. Ophthalmol. Vis. Sci. , vol.33 , pp. 3125-3130
    • Moritera, T.1
  • 33
    • 77950934957 scopus 로고    scopus 로고
    • Phase I/II study of intravitreal triamcinolone acetonide microspheres for treatment of diffuse diabetic macular edema unresponsive to conventional laser photocoagulation treatment
    • E-Abstract 2698 (online)
    • Lavinsky D., et al. Phase I/II study of intravitreal triamcinolone acetonide microspheres for treatment of diffuse diabetic macular edema unresponsive to conventional laser photocoagulation treatment. Invest. Ophthalmol. Vis. Sci. 2008, 49. E-Abstract 2698 (online).
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49
    • Lavinsky, D.1
  • 34
    • 33747874701 scopus 로고    scopus 로고
    • A PEDF N-terminal peptide protects the retina from ischemic injury when delivered in PLGA nanospheres
    • Li H., et al. A PEDF N-terminal peptide protects the retina from ischemic injury when delivered in PLGA nanospheres. Exp. Eye Res. 2006, 83:824-833.
    • (2006) Exp. Eye Res. , vol.83 , pp. 824-833
    • Li, H.1
  • 35
    • 34748880897 scopus 로고    scopus 로고
    • PEGylated bioactive molecules in biodegradable polymer microparticles
    • Schmidt P.G., et al. PEGylated bioactive molecules in biodegradable polymer microparticles. Expert Opin. Biol. Ther. 2007, 7:1427-1436.
    • (2007) Expert Opin. Biol. Ther. , vol.7 , pp. 1427-1436
    • Schmidt, P.G.1
  • 36
    • 34249787025 scopus 로고    scopus 로고
    • Ocular drug delivery: nanomedicine applications
    • Vandervoort J., Ludwig A. Ocular drug delivery: nanomedicine applications. Nanomedicine 2007, 2:11-21.
    • (2007) Nanomedicine , vol.2 , pp. 11-21
    • Vandervoort, J.1    Ludwig, A.2
  • 37
    • 41149178633 scopus 로고    scopus 로고
    • Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema
    • Doukas J., et al. Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema. J. Cell. Physiol. 2008, 216:29-37.
    • (2008) J. Cell. Physiol. , vol.216 , pp. 29-37
    • Doukas, J.1
  • 38
    • 0022852854 scopus 로고
    • Topical ocular drug delivery: recent developments and future challenges
    • Lee V.H., Robinson J.R. Topical ocular drug delivery: recent developments and future challenges. J. Ocul. Pharmacol. 1986, 2:67-108.
    • (1986) J. Ocul. Pharmacol. , vol.2 , pp. 67-108
    • Lee, V.H.1    Robinson, J.R.2
  • 39
    • 0031772606 scopus 로고    scopus 로고
    • Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye
    • Prausnitz M.R., Noonan J.S. Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye. J. Pharm. Sci. 1998, 87:1479-1488.
    • (1998) J. Pharm. Sci. , vol.87 , pp. 1479-1488
    • Prausnitz, M.R.1    Noonan, J.S.2
  • 40
    • 0842283719 scopus 로고    scopus 로고
    • Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva, and sclera
    • Hamalainen K.M., et al. Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva, and sclera. Invest. Ophthalmol. Vis. Sci. 1997, 38:627-634.
    • (1997) Invest. Ophthalmol. Vis. Sci. , vol.38 , pp. 627-634
    • Hamalainen, K.M.1
  • 41
    • 0023239876 scopus 로고
    • A gamma scintigraphic evaluation of the precorneal residence of liposomal formulations in the rabbit
    • Fitzgerald P., et al. A gamma scintigraphic evaluation of the precorneal residence of liposomal formulations in the rabbit. J. Pharm. Pharmacol. 1987, 39:487-490.
    • (1987) J. Pharm. Pharmacol. , vol.39 , pp. 487-490
    • Fitzgerald, P.1
  • 42
    • 35048821557 scopus 로고    scopus 로고
    • Transport barriers in transscleral drug delivery for retinal diseases
    • Kim S.H., et al. Transport barriers in transscleral drug delivery for retinal diseases. Ophthalmic Res. 2007, 39:244-254.
    • (2007) Ophthalmic Res. , vol.39 , pp. 244-254
    • Kim, S.H.1
  • 43
    • 53149104782 scopus 로고    scopus 로고
    • Human transscleral albumin permeability and the effect of topographical location and donor age
    • Anderson O.A., et al. Human transscleral albumin permeability and the effect of topographical location and donor age. Invest. Ophthalmol. Vis. Sci. 2008, 49:4041-4045.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 4041-4045
    • Anderson, O.A.1
  • 44
    • 31344468895 scopus 로고    scopus 로고
    • A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide
    • Robinson M.R., et al. A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide. Exp. Eye Res. 2006, 82:479-487.
    • (2006) Exp. Eye Res. , vol.82 , pp. 479-487
    • Robinson, M.R.1
  • 46
    • 0000510983 scopus 로고
    • The drainage of albumin from the uvea
    • Bill A. The drainage of albumin from the uvea. Exp. Eye Res. 1964, 3:179-187.
    • (1964) Exp. Eye Res. , vol.3 , pp. 179-187
    • Bill, A.1
  • 47
    • 3242885512 scopus 로고    scopus 로고
    • Controlled drug release from an ocular implant: an evaluation using dynamic three-dimensional magnetic resonance imaging
    • Kim H., et al. Controlled drug release from an ocular implant: an evaluation using dynamic three-dimensional magnetic resonance imaging. Invest. Ophthalmol. Vis. Sci. 2004, 45:2722-2731.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 2722-2731
    • Kim, H.1
  • 48
    • 0347358065 scopus 로고    scopus 로고
    • Feasibility of drug delivery to the posterior pole of the rabbit eye with an episcleral implant
    • Kato A., et al. Feasibility of drug delivery to the posterior pole of the rabbit eye with an episcleral implant. Invest. Ophthalmol. Vis. Sci. 2004, 45:238-244.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 238-244
    • Kato, A.1
  • 49
    • 0037308517 scopus 로고    scopus 로고
    • Biodegradable intrascleral implant for sustained intraocular delivery of betamethasone phosphate
    • Okabe J., et al. Biodegradable intrascleral implant for sustained intraocular delivery of betamethasone phosphate. Invest. Ophthalmol. Vis. Sci. 2003, 44:740-744.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 740-744
    • Okabe, J.1
  • 50
    • 0037809363 scopus 로고    scopus 로고
    • Intraocular tissue distribution of betamethasone after intrascleral administration using a non-biodegradable sustained drug delivery device
    • Okabe K., et al. Intraocular tissue distribution of betamethasone after intrascleral administration using a non-biodegradable sustained drug delivery device. Invest. Ophthalmol. Vis. Sci. 2003, 44:2702-2707.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 2702-2707
    • Okabe, K.1
  • 51
    • 33745655043 scopus 로고    scopus 로고
    • A novel bioerodible deep scleral lamellar cyclosporine implant for uveitis
    • Gilger B.C., et al. A novel bioerodible deep scleral lamellar cyclosporine implant for uveitis. Invest. Ophthalmol. Vis. Sci. 2006, 47:2596-2605.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 2596-2605
    • Gilger, B.C.1
  • 52
    • 33750086968 scopus 로고    scopus 로고
    • Cannulation of the suprachoroidal space: a novel drug delivery methodology to the posterior segment
    • Olsen T.W., et al. Cannulation of the suprachoroidal space: a novel drug delivery methodology to the posterior segment. Am. J. Ophthalmol. 2006, 142:777-787.
    • (2006) Am. J. Ophthalmol. , vol.142 , pp. 777-787
    • Olsen, T.W.1
  • 53
    • 0032410376 scopus 로고    scopus 로고
    • Comparison of the ocular distribution of a model oligonucleotide after topical instillation in rabbits of conventional and new dosage forms
    • Bochot A., et al. Comparison of the ocular distribution of a model oligonucleotide after topical instillation in rabbits of conventional and new dosage forms. J. Drug Target. 1998, 6:309-313.
    • (1998) J. Drug Target. , vol.6 , pp. 309-313
    • Bochot, A.1
  • 54
    • 0037251511 scopus 로고    scopus 로고
    • Controlled delivery of the anti-VEGF aptamer EYE001 with poly(lactic-co-glycolic)acid microspheres
    • Carrasquillo K.G., et al. Controlled delivery of the anti-VEGF aptamer EYE001 with poly(lactic-co-glycolic)acid microspheres. Invest. Ophthalmol. Vis. Sci. 2003, 44:290-299.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 290-299
    • Carrasquillo, K.G.1
  • 55
    • 0036069080 scopus 로고    scopus 로고
    • Down-regulation of NOSII gene expression by iontophoresis of anti-sense oligonucleotide in endotoxin-induced uveitis
    • Voigt M., et al. Down-regulation of NOSII gene expression by iontophoresis of anti-sense oligonucleotide in endotoxin-induced uveitis. Biochem. Biophys. Res. Commun. 2002, 295:336-341.
    • (2002) Biochem. Biophys. Res. Commun. , vol.295 , pp. 336-341
    • Voigt, M.1
  • 56
    • 0038303190 scopus 로고    scopus 로고
    • Tolerance of ocular iontophoresis in healthy volunteers
    • Parkinson T.M., et al. Tolerance of ocular iontophoresis in healthy volunteers. J. Ocul. Pharmacol. Ther. 2003, 19:145-151.
    • (2003) J. Ocul. Pharmacol. Ther. , vol.19 , pp. 145-151
    • Parkinson, T.M.1
  • 57
    • 0842331139 scopus 로고    scopus 로고
    • Iontophoresis: from the lab to the bed side
    • Halhal M., et al. Iontophoresis: from the lab to the bed side. Exp. Eye Res. 2004, 78:751-757.
    • (2004) Exp. Eye Res. , vol.78 , pp. 751-757
    • Halhal, M.1
  • 58
    • 38749127952 scopus 로고    scopus 로고
    • Charged nanoparticles delivery to the eye using hydrogel iontophoresis
    • Eljarrat-Binstock E., et al. Charged nanoparticles delivery to the eye using hydrogel iontophoresis. J. Control. Release 2008, 126:156-161.
    • (2008) J. Control. Release , vol.126 , pp. 156-161
    • Eljarrat-Binstock, E.1
  • 59
    • 28744440082 scopus 로고    scopus 로고
    • Dendrimers in gene delivery
    • Dufes C., et al. Dendrimers in gene delivery. Adv. Drug Deliv. Rev. 2005, 57:2177-2202.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 2177-2202
    • Dufes, C.1
  • 60
    • 21644468948 scopus 로고    scopus 로고
    • Nanoparticles for gene delivery to retinal pigment epithelial cells
    • Bejjani R.A., et al. Nanoparticles for gene delivery to retinal pigment epithelial cells. Mol. Vis. 2005, 11:124-132.
    • (2005) Mol. Vis. , vol.11 , pp. 124-132
    • Bejjani, R.A.1
  • 61
    • 85047699046 scopus 로고    scopus 로고
    • Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1
    • Bainbridge J.W., et al. Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1. Gene Ther. 2002, 9:320-326.
    • (2002) Gene Ther. , vol.9 , pp. 320-326
    • Bainbridge, J.W.1
  • 62
    • 58149478117 scopus 로고    scopus 로고
    • Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization
    • Pechan P., et al. Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization. Gene Ther. 2009, 16:10-16.
    • (2009) Gene Ther. , vol.16 , pp. 10-16
    • Pechan, P.1
  • 63
    • 0031687272 scopus 로고    scopus 로고
    • Immune responses limit adenovirally mediated gene expression in the adult mouse eye
    • Reichel M.B., et al. Immune responses limit adenovirally mediated gene expression in the adult mouse eye. Gene Ther. 1998, 5:1038-1046.
    • (1998) Gene Ther. , vol.5 , pp. 1038-1046
    • Reichel, M.B.1
  • 64
    • 0035836697 scopus 로고    scopus 로고
    • Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer
    • Kuo C.J., et al. Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:4605-4610.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 4605-4610
    • Kuo, C.J.1
  • 65
    • 32944481724 scopus 로고    scopus 로고
    • Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: results of a phase I clinical trial
    • Campochiaro P.A., et al. Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: results of a phase I clinical trial. Hum. Gene Ther. 2006, 17:167-176.
    • (2006) Hum. Gene Ther. , vol.17 , pp. 167-176
    • Campochiaro, P.A.1
  • 66
    • 0036297886 scopus 로고    scopus 로고
    • Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor
    • Mori K., et al. Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor. Invest. Ophthalmol. Vis. Sci. 2002, 43:2428-2434.
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 2428-2434
    • Mori, K.1
  • 67
    • 0038742908 scopus 로고    scopus 로고
    • Periocular injection of an adenoviral vector encoding pigment epithelium-derived factor inhibits choroidal neovascularization
    • Gehlbach P., et al. Periocular injection of an adenoviral vector encoding pigment epithelium-derived factor inhibits choroidal neovascularization. Gene Ther. 2003, 10:637-646.
    • (2003) Gene Ther. , vol.10 , pp. 637-646
    • Gehlbach, P.1
  • 68
    • 20844447893 scopus 로고    scopus 로고
    • Periocular gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization in a human-sized eye
    • Saishin Y., et al. Periocular gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization in a human-sized eye. Hum. Gene Ther. 2005, 16:473-478.
    • (2005) Hum. Gene Ther. , vol.16 , pp. 473-478
    • Saishin, Y.1
  • 69
    • 0038724167 scopus 로고    scopus 로고
    • Gene therapy for ocular angiogenesis
    • Bainbridge J.W., et al. Gene therapy for ocular angiogenesis. Clin. Sci. (Lond.) 2003, 104:561-575.
    • (2003) Clin. Sci. (Lond.) , vol.104 , pp. 561-575
    • Bainbridge, J.W.1
  • 70
    • 44249120315 scopus 로고    scopus 로고
    • Effect of gene therapy on visual function in Leber's congenital amaurosis
    • Bainbridge J.W., et al. Effect of gene therapy on visual function in Leber's congenital amaurosis. N. Engl. J. Med. 2008, 358:2231-2239.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2231-2239
    • Bainbridge, J.W.1
  • 71
    • 54449085219 scopus 로고    scopus 로고
    • Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics
    • Cideciyan A.V., et al. Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:15112-15117.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 15112-15117
    • Cideciyan, A.V.1
  • 72
    • 44249085878 scopus 로고    scopus 로고
    • Safety and efficacy of gene transfer for Leber's congenital amaurosis
    • Maguire A.M., et al. Safety and efficacy of gene transfer for Leber's congenital amaurosis. N. Engl. J. Med. 2008, 358:2240-2248.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2240-2248
    • Maguire, A.M.1
  • 73
    • 0034984667 scopus 로고    scopus 로고
    • Recombinant AAV-mediated delivery of a tet-inducible reporter gene to the rat retina
    • McGee Sanftner L.H., et al. Recombinant AAV-mediated delivery of a tet-inducible reporter gene to the rat retina. Mol. Ther. 2001, 3:688-696.
    • (2001) Mol. Ther. , vol.3 , pp. 688-696
    • McGee Sanftner, L.H.1
  • 74
    • 0036664935 scopus 로고    scopus 로고
    • Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye
    • Auricchio A., et al. Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye. Mol. Ther. 2002, 6:238-242.
    • (2002) Mol. Ther. , vol.6 , pp. 238-242
    • Auricchio, A.1
  • 75
    • 0037564988 scopus 로고    scopus 로고
    • Hypoxia-regulated transgene expression in experimental retinal and choroidal neovascularization
    • Bainbridge J.W., et al. Hypoxia-regulated transgene expression in experimental retinal and choroidal neovascularization. Gene Ther. 2003, 10:1049-1054.
    • (2003) Gene Ther. , vol.10 , pp. 1049-1054
    • Bainbridge, J.W.1
  • 76
    • 33644872951 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants
    • Sieving P.A., et al. Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:3896-3901.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 3896-3901
    • Sieving, P.A.1
  • 77
    • 13044263133 scopus 로고    scopus 로고
    • Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2 delays photoreceptor cell degeneration in Royal College of Surgeons rats
    • Uteza Y., et al. Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2 delays photoreceptor cell degeneration in Royal College of Surgeons rats. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:3126-3131.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 3126-3131
    • Uteza, Y.1
  • 78
    • 0034033525 scopus 로고    scopus 로고
    • Mammalian-cell-produced neurturin (NTN) is more potent than purified Escherichia coli-produced NTN
    • Hoane M.R., et al. Mammalian-cell-produced neurturin (NTN) is more potent than purified Escherichia coli-produced NTN. Exp. Neurol. 2000, 162:189-193.
    • (2000) Exp. Neurol. , vol.162 , pp. 189-193
    • Hoane, M.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.