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Volumn 49, Issue 1, 2008, Pages 320-332

Modeling of corneal and retinal pharmacokinetics after periocular drug administration

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; PREDNISOLONE; CYCLOOXYGENASE 2 INHIBITOR; GLUCOCORTICOID; PYRAZOLE DERIVATIVE; SULFONAMIDE;

EID: 38749087775     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-0593     Document Type: Article
Times cited : (72)

References (60)
  • 1
    • 0036669505 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment from drops
    • Maurice DM. Drug delivery to the posterior segment from drops. Surv Ophthalmol. 2002;47(suppl 1):S41-S52.
    • (2002) Surv Ophthalmol , vol.47 , Issue.SUPPL. 1
    • Maurice, D.M.1
  • 3
    • 33751192060 scopus 로고    scopus 로고
    • Transscleral drug delivery to the posterior eye: Prospects of pharmacokinetic modeling
    • Ranta VP, Urtti A. Transscleral drug delivery to the posterior eye: prospects of pharmacokinetic modeling. Adv Drug Deliv Rev. 2006;58:1164-1181.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1164-1181
    • Ranta, V.P.1    Urtti, A.2
  • 4
    • 0023835180 scopus 로고
    • Intraocular penetration kinetics of prednisolone after subconjunctival injection in rabbits
    • Tsuji A, Tamai I, Sasaki K. Intraocular penetration kinetics of prednisolone after subconjunctival injection in rabbits. Ophthalmic Res. 1988;20:31-43.
    • (1988) Ophthalmic Res , vol.20 , pp. 31-43
    • Tsuji, A.1    Tamai, I.2    Sasaki, K.3
  • 5
    • 1042277993 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye II: Development and validation of a simple pharmacokinetic model for subconjunctival injection
    • Lee TW, Robinson JR. Drug delivery to the posterior segment of the eye II: development and validation of a simple pharmacokinetic model for subconjunctival injection. J Ocul Pharmacol Ther. 2004;20:43-53.
    • (2004) J Ocul Pharmacol Ther , vol.20 , pp. 43-53
    • Lee, T.W.1    Robinson, J.R.2
  • 6
    • 0032799705 scopus 로고    scopus 로고
    • High concentration of dexamethasone in aqueous and vitreous after subconjunctival injection
    • Weijtens O, Feron EJ, Schoemaker RC, et al. High concentration of dexamethasone in aqueous and vitreous after subconjunctival injection. Am J Ophthalmol. 1999;128:192-197.
    • (1999) Am J Ophthalmol , vol.128 , pp. 192-197
    • Weijtens, O.1    Feron, E.J.2    Schoemaker, R.C.3
  • 7
    • 0021265034 scopus 로고
    • Pharmacokinetics and metabolism of 5-fluorouracil following subconjunctival versus intravenous administration
    • Rootman J, Ostry A, Gudauskas G. Pharmacokinetics and metabolism of 5-fluorouracil following subconjunctival versus intravenous administration. Can J Ophthalmol. 1984;19:187-191.
    • (1984) Can J Ophthalmol , vol.19 , pp. 187-191
    • Rootman, J.1    Ostry, A.2    Gudauskas, G.3
  • 8
    • 0034771378 scopus 로고    scopus 로고
    • Vancomycin levels in human aqueous humour after intravenous and subconjunctival administration
    • Souli M, Kopsinis G, Kavouklis E, Gabriel L, Giamarellou H. Vancomycin levels in human aqueous humour after intravenous and subconjunctival administration. Int J Antimicrob Agents. 2001;18:239-243.
    • (2001) Int J Antimicrob Agents , vol.18 , pp. 239-243
    • Souli, M.1    Kopsinis, G.2    Kavouklis, E.3    Gabriel, L.4    Giamarellou, H.5
  • 9
    • 34248680469 scopus 로고    scopus 로고
    • Rowland M, Balant L, Peck C. Physiologically based pharmacokinetics in drug development and regulatory science: a workshop report. Georgetown University, Washington, DC, May 29-30, 2002. AAPS PharmSci. 2004;6:E6.
    • Rowland M, Balant L, Peck C. Physiologically based pharmacokinetics in drug development and regulatory science: a workshop report. Georgetown University, Washington, DC, May 29-30, 2002. AAPS PharmSci. 2004;6:E6.
  • 10
    • 16644391550 scopus 로고    scopus 로고
    • A human PBPK model for ethanol describing inhibition of gastric motility
    • Loizou GD, Spendiff M. A human PBPK model for ethanol describing inhibition of gastric motility. J Mol Histol. 2004;35:687-696.
    • (2004) J Mol Histol , vol.35 , pp. 687-696
    • Loizou, G.D.1    Spendiff, M.2
  • 12
    • 6344284095 scopus 로고    scopus 로고
    • Retinal delivery of celecoxib is several-fold higher following subconjunctival administration compared to systemic administration
    • Ayalasomayajula SP, Kompella UB. Retinal delivery of celecoxib is several-fold higher following subconjunctival administration compared to systemic administration. Pharm Res. 2004;21:1797-1804.
    • (2004) Pharm Res , vol.21 , pp. 1797-1804
    • Ayalasomayajula, S.P.1    Kompella, U.B.2
  • 13
    • 17644426066 scopus 로고    scopus 로고
    • Assessment of subconjunctival delivery with model ionic permeants and magnetic resonance imaging
    • Li SK, Molokhia SA, Jeong EK. Assessment of subconjunctival delivery with model ionic permeants and magnetic resonance imaging. Pharm Res. 2004;21:2175-2184.
    • (2004) Pharm Res , vol.21 , pp. 2175-2184
    • Li, S.K.1    Molokhia, S.A.2    Jeong, E.K.3
  • 14
    • 31344468895 scopus 로고    scopus 로고
    • A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide
    • Robinson MR, Lee SS, Kim H, et al. A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide. Exp Eye Res. 2006;82:479-487.
    • (2006) Exp Eye Res , vol.82 , pp. 479-487
    • Robinson, M.R.1    Lee, S.S.2    Kim, H.3
  • 15
    • 33847710274 scopus 로고    scopus 로고
    • Assessment of subconjunctival and intrascleral drug delivery to the posterior segment using dynamic contrast-enhanced magnetic resonance imaging
    • Kim SH, Galban CJ, Lutz RJ, et al. Assessment of subconjunctival and intrascleral drug delivery to the posterior segment using dynamic contrast-enhanced magnetic resonance imaging. Invest Ophthalmol Vis Sci. 2007;48:808-814.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 808-814
    • Kim, S.H.1    Galban, C.J.2    Lutz, R.J.3
  • 16
    • 0018761015 scopus 로고
    • Pharmacokinetics of topically applied pilocarpine in the albino rabbit eye
    • Makoid MC, Robinson JR. Pharmacokinetics of topically applied pilocarpine in the albino rabbit eye. J Pharm Sci. 1979;68:435-443.
    • (1979) J Pharm Sci , vol.68 , pp. 435-443
    • Makoid, M.C.1    Robinson, J.R.2
  • 17
    • 0002611505 scopus 로고
    • Ocular pharmacokintics
    • Sears ML, ed, New York: Springer;
    • Maurice DM, Mishima S. Ocular pharmacokintics. In: Sears ML, ed. Pharmacology of the Eye. New York: Springer; 1984:19-116.
    • (1984) Pharmacology of the Eye , pp. 19-116
    • Maurice, D.M.1    Mishima, S.2
  • 18
    • 0032819839 scopus 로고    scopus 로고
    • Topical delivery system of ophthalmic drugs by periocular injection with viscous solution
    • Sasaki H, Kashiwagi S, Mukai T, et al. Topical delivery system of ophthalmic drugs by periocular injection with viscous solution. Biol Pharm Bull. 1999;22:961-965.
    • (1999) Biol Pharm Bull , vol.22 , pp. 961-965
    • Sasaki, H.1    Kashiwagi, S.2    Mukai, T.3
  • 19
    • 0032821187 scopus 로고    scopus 로고
    • Drug absorption behavior after periocular injections
    • Sasaki H, Kashiwagi S, Mukai T, et al. Drug absorption behavior after periocular injections. Biol Pharm Bull. 1999;22:956-960.
    • (1999) Biol Pharm Bull , vol.22 , pp. 956-960
    • Sasaki, H.1    Kashiwagi, S.2    Mukai, T.3
  • 20
    • 0001643202 scopus 로고
    • The ocular uptake of subconjunctivally injected 14C-hydrocortisone
    • Wine NA, Gornall AG, Basu PK. The ocular uptake of subconjunctivally injected 14C-hydrocortisone. Am J Ophthalmol. 1964;58:362-366.
    • (1964) Am J Ophthalmol , vol.58 , pp. 362-366
    • Wine, N.A.1    Gornall, A.G.2    Basu, P.K.3
  • 21
    • 13944270207 scopus 로고    scopus 로고
    • Preclinical evaluation of a novel episcleral cyclosporine implant for ocular graft-versus-host disease
    • Kim H, Csaky KG, Gilger BC, et al. Preclinical evaluation of a novel episcleral cyclosporine implant for ocular graft-versus-host disease. Invest Ophthalmol Vis Sci. 2005;46:655-662.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 655-662
    • Kim, H.1    Csaky, K.G.2    Gilger, B.C.3
  • 22
    • 34250163903 scopus 로고    scopus 로고
    • A pharmacokinetic and safety evaluation of an episcleral cyclosporine implant for potential use in high-risk keratoplasty rejection
    • Lee SS, Kim H, Wang NS, et al. A pharmacokinetic and safety evaluation of an episcleral cyclosporine implant for potential use in high-risk keratoplasty rejection. Invest Ophthalmol Vis Sci. 2007;48:2023-2029.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 2023-2029
    • Lee, S.S.1    Kim, H.2    Wang, N.S.3
  • 23
    • 0015061302 scopus 로고
    • Intraocular sporotrichosis. Report of a case
    • Levy JH. Intraocular sporotrichosis. Report of a case. Arch Ophthalmol. 1971;85:574-579.
    • (1971) Arch Ophthalmol , vol.85 , pp. 574-579
    • Levy, J.H.1
  • 24
    • 0014262495 scopus 로고
    • Procaine interaction with the corneal surface and its relation to anesthesia
    • Smolen VF, Siegel FP. Procaine interaction with the corneal surface and its relation to anesthesia. J Pharm Sci. 1967;57:378-384.
    • (1967) J Pharm Sci , vol.57 , pp. 378-384
    • Smolen, V.F.1    Siegel, F.P.2
  • 26
    • 0035198492 scopus 로고    scopus 로고
    • Contribution of lymphatic drainage system in corneal allograft rejection in mice
    • Hoffmann F, Zhang EP, Mueller A, et al. Contribution of lymphatic drainage system in corneal allograft rejection in mice. Graefes Arch Clin Exp Ophthalmol. 2001;239:850-858.
    • (2001) Graefes Arch Clin Exp Ophthalmol , vol.239 , pp. 850-858
    • Hoffmann, F.1    Zhang, E.P.2    Mueller, A.3
  • 28
    • 0036828057 scopus 로고    scopus 로고
    • Predicting solubility in multiple nonpolar drugs-cyclodextrin system
    • Zhao L, Orton E, Vemuri NM. Predicting solubility in multiple nonpolar drugs-cyclodextrin system. J Pharm Sci. 2002;91:2301-2306.
    • (2002) J Pharm Sci , vol.91 , pp. 2301-2306
    • Zhao, L.1    Orton, E.2    Vemuri, N.M.3
  • 29
    • 33646822128 scopus 로고    scopus 로고
    • Improved solubilization of Celecoxib in U-type nonionic microemulsions and their structural transitions with progressive aqueous dilution
    • Garti N, Avrahami M, Aserin A. Improved solubilization of Celecoxib in U-type nonionic microemulsions and their structural transitions with progressive aqueous dilution. J Colloid Interface Sci. 2006;299:352-365.
    • (2006) J Colloid Interface Sci , vol.299 , pp. 352-365
    • Garti, N.1    Avrahami, M.2    Aserin, A.3
  • 30
    • 23144465464 scopus 로고    scopus 로고
    • Solubility enhancement of Cox-2 inhibitors using various solvent systems
    • Seedher N, Bhatia S. Solubility enhancement of Cox-2 inhibitors using various solvent systems. AAPS PharmSciTech. 2003;4:E33.
    • (2003) AAPS PharmSciTech , vol.4
    • Seedher, N.1    Bhatia, S.2
  • 31
    • 33846258743 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of anecortave acetate in animals and humans
    • Dahlin DC, Rahimy MH. Pharmacokinetics and metabolism of anecortave acetate in animals and humans. Surv Ophthalmol. 2007;52(suppl 1):S49-S61.
    • (2007) Surv Ophthalmol , vol.52 , Issue.SUPPL. 1
    • Dahlin, D.C.1    Rahimy, M.H.2
  • 32
    • 33846220906 scopus 로고    scopus 로고
    • Posterior juxtascleral depot administration of anecortave acetate
    • Kaiser PK, Goldberg MF, Davis AA. Posterior juxtascleral depot administration of anecortave acetate. Surv Ophthalmol. 2007;52(suppl 1):S62-S69.
    • (2007) Surv Ophthalmol , vol.52 , Issue.SUPPL. 1
    • Kaiser, P.K.1    Goldberg, M.F.2    Davis, A.A.3
  • 33
    • 0142231905 scopus 로고    scopus 로고
    • Periocular injection of microspheres containing PKC412 inhibits choroidal neovascularization in a porcine model
    • Saishin Y, Silva RL, Saishin Y, et al. Periocular injection of microspheres containing PKC412 inhibits choroidal neovascularization in a porcine model. Invest Ophthalmol Vis Sci. 2003;44:4989-4993.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4989-4993
    • Saishin, Y.1    Silva, R.L.2    Saishin, Y.3
  • 34
    • 13944251659 scopus 로고    scopus 로고
    • Effect of benzalkonium chloride on transscleral drug delivery
    • Okabe K, Kimura H, Okabe J, et al. Effect of benzalkonium chloride on transscleral drug delivery. Invest Ophthalmol Vis Sci. 2005;46:703-708.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 703-708
    • Okabe, K.1    Kimura, H.2    Okabe, J.3
  • 35
    • 4644256574 scopus 로고    scopus 로고
    • Pharmacokinetics of systemic versus focal Carboplatin chemotherapy in the rabbit eye: Possible implication in the treatment of retinoblastoma
    • Hayden BC, Jockovich ME, Murray TG, et al. Pharmacokinetics of systemic versus focal Carboplatin chemotherapy in the rabbit eye: possible implication in the treatment of retinoblastoma. Invest Ophthalmol Vis Sci. 2004;45:3644-3649.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 3644-3649
    • Hayden, B.C.1    Jockovich, M.E.2    Murray, T.G.3
  • 36
    • 33645403444 scopus 로고    scopus 로고
    • Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage
    • Amrite AC, Ayalasomayajula SP, Cheruvu NP, Kompella UB. Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage. Invest Ophthalmol Vis Sci. 2006;47:1149-1160.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 1149-1160
    • Amrite, A.C.1    Ayalasomayajula, S.P.2    Cheruvu, N.P.3    Kompella, U.B.4
  • 37
    • 15744404419 scopus 로고    scopus 로고
    • Subconjunctivally administered celecoxib-PLGA microparticles sustain retinal drug levels and alleviate diabetes-induced oxidative stress in a rat model
    • Ayalasomayajula SP, Kompella UB. Subconjunctivally administered celecoxib-PLGA microparticles sustain retinal drug levels and alleviate diabetes-induced oxidative stress in a rat model. Eur J Pharmacol. 2005;511:191-198.
    • (2005) Eur J Pharmacol , vol.511 , pp. 191-198
    • Ayalasomayajula, S.P.1    Kompella, U.B.2
  • 38
    • 0037336290 scopus 로고    scopus 로고
    • Subconjunctival nanoand microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression
    • Kompella UB, Bandi N, Ayalasomayajula SP. Subconjunctival nanoand microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression. Invest Ophthalmol Vis Sci. 2003;44:1192-1201.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 1192-1201
    • Kompella, U.B.1    Bandi, N.2    Ayalasomayajula, S.P.3
  • 39
    • 0027177256 scopus 로고
    • Intraocular dexamethasone penetration via subconjunctival or retrobulbar injections in rabbits
    • Bodker FS, Ticho BH, Feist RM, Lam TT. Intraocular dexamethasone penetration via subconjunctival or retrobulbar injections in rabbits. Ophthalmic Surg. 1993;24:453-457.
    • (1993) Ophthalmic Surg , vol.24 , pp. 453-457
    • Bodker, F.S.1    Ticho, B.H.2    Feist, R.M.3    Lam, T.T.4
  • 40
    • 0036846562 scopus 로고    scopus 로고
    • Subconjunctival administration of bucillamine suppresses choroidal neovascularization in rat
    • Yanagi Y, Tamaki Y, Obata R, et al. Subconjunctival administration of bucillamine suppresses choroidal neovascularization in rat. Invest Ophthalmol Vis Sci. 2002;43:3495-3499.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3495-3499
    • Yanagi, Y.1    Tamaki, Y.2    Obata, R.3
  • 41
    • 1042301272 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye III: The effect of parallel elimination pathway on the vitreous drug level after subconjunctival injection
    • Lee TW, Robinson JR. Drug delivery to the posterior segment of the eye III: the effect of parallel elimination pathway on the vitreous drug level after subconjunctival injection. J Ocul Pharmacol Ther. 2004;20:55-64.
    • (2004) J Ocul Pharmacol Ther , vol.20 , pp. 55-64
    • Lee, T.W.1    Robinson, J.R.2
  • 42
    • 0015309358 scopus 로고
    • The oxygen supply to the retina. 2. Effects of high intraocular pressure and of increased arterial carbon dioxide tension on uveal and retinal blood flow in cats. A study with labelled microspheres including flow determination in brain and other tissues
    • Alm A, Bill A. The oxygen supply to the retina. 2. Effects of high intraocular pressure and of increased arterial carbon dioxide tension on uveal and retinal blood flow in cats. A study with labelled microspheres including flow determination in brain and other tissues. Acta Physiol Scand. 1972;84:306-319.
    • (1972) Acta Physiol Scand , vol.84 , pp. 306-319
    • Alm, A.1    Bill, A.2
  • 43
    • 0000394397 scopus 로고
    • Retinal and choroidal blood flow determined with Krypton-85 anesthetized animals
    • Friedman E, Kopald HH, Smith TR. Retinal and choroidal blood flow determined with Krypton-85 anesthetized animals. Invest Ophthalmol. 1964;3:539-547.
    • (1964) Invest Ophthalmol , vol.3 , pp. 539-547
    • Friedman, E.1    Kopald, H.H.2    Smith, T.R.3
  • 44
    • 0023739464 scopus 로고
    • Retinal blood flow and its autoregulation measured by intraocular hydrogen clearance
    • Stefansson E, Wagner HG, Seida M. Retinal blood flow and its autoregulation measured by intraocular hydrogen clearance. Exp Eye Res. 1988;47:669-678.
    • (1988) Exp Eye Res , vol.47 , pp. 669-678
    • Stefansson, E.1    Wagner, H.G.2    Seida, M.3
  • 45
    • 0026076607 scopus 로고
    • Measurement of blood flow in rat eyes by hydrogen clearance
    • Yu DY, Alder VA, Cringle SJ. Measurement of blood flow in rat eyes by hydrogen clearance. Am J Physiol. 1991;261:H960-H968.
    • (1991) Am J Physiol , vol.261
    • Yu, D.Y.1    Alder, V.A.2    Cringle, S.J.3
  • 46
    • 0020078274 scopus 로고
    • The movement of xenon-133 from the vitreous to the choroid
    • Moseley H, Foulds WS. The movement of xenon-133 from the vitreous to the choroid. Exp Eye Res. 1982;34:169-179.
    • (1982) Exp Eye Res , vol.34 , pp. 169-179
    • Moseley, H.1    Foulds, W.S.2
  • 47
    • 0021671169 scopus 로고
    • Routes of clearance of radioactive water from the rabbit vitreous
    • Moseley H, Foulds WS, Allan D, Kyle PM. Routes of clearance of radioactive water from the rabbit vitreous. Br J Ophthalmol. 1984;68:145-151.
    • (1984) Br J Ophthalmol , vol.68 , pp. 145-151
    • Moseley, H.1    Foulds, W.S.2    Allan, D.3    Kyle, P.M.4
  • 48
    • 3242885512 scopus 로고    scopus 로고
    • Controlled drug release from an ocular implant: An evaluation using dynamic three-dimensional magnetic resonance imaging
    • Kim H, Robinson MR, Lizak MJ, et al. Controlled drug release from an ocular implant: an evaluation using dynamic three-dimensional magnetic resonance imaging. Invest Ophthalmol Vis Sci. 2004;45:2722-2731.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2722-2731
    • Kim, H.1    Robinson, M.R.2    Lizak, M.J.3
  • 49
    • 21744435077 scopus 로고    scopus 로고
    • Evaluation of coupled convective-diffusive transport of drugs administered by intravitreal injection and controlled release implant
    • Park J, Bungay PM, Lutz RJ, et al. Evaluation of coupled convective-diffusive transport of drugs administered by intravitreal injection and controlled release implant. J Control Release. 2005;105:279-295.
    • (2005) J Control Release , vol.105 , pp. 279-295
    • Park, J.1    Bungay, P.M.2    Lutz, R.J.3
  • 50
    • 0036882372 scopus 로고    scopus 로고
    • Finite and infinitesimal representations of the vasculature: Ocular drug clearance by vascular and hydraulic effects
    • Missel PJ. Finite and infinitesimal representations of the vasculature: ocular drug clearance by vascular and hydraulic effects. Ann Biomed Eng. 2002;30:1128-1139.
    • (2002) Ann Biomed Eng , vol.30 , pp. 1128-1139
    • Missel, P.J.1
  • 51
    • 0036845775 scopus 로고    scopus 로고
    • Hydraulic flow and vascular clearance influences on intravitreal drug delivery
    • Missel PJ. Hydraulic flow and vascular clearance influences on intravitreal drug delivery. Pharm Res. 2002;19:1636-47.
    • (2002) Pharm Res , vol.19 , pp. 1636-1647
    • Missel, P.J.1
  • 53
    • 0031593982 scopus 로고    scopus 로고
    • Distribution of mitochondria within Muller cells, I. Correlation with retinal vascularization in different mammalian species
    • Germer A, Biedermann B, Wolburg H, et al. Distribution of mitochondria within Muller cells, I. Correlation with retinal vascularization in different mammalian species. J Neurocytol. 1998;27:329-345.
    • (1998) J Neurocytol , vol.27 , pp. 329-345
    • Germer, A.1    Biedermann, B.2    Wolburg, H.3
  • 54
    • 0001364939 scopus 로고
    • Movement of albumin and dextran through the sclera
    • Bill A. Movement of albumin and dextran through the sclera. Arch Ophthalmol. 1965;74:248-252.
    • (1965) Arch Ophthalmol , vol.74 , pp. 248-252
    • Bill, A.1
  • 55
    • 0014316529 scopus 로고
    • Capillary permeability to and extravascular dymanics of myoglobin, albumin and gammaglobulin in the uvea
    • Bill A. Capillary permeability to and extravascular dymanics of myoglobin, albumin and gammaglobulin in the uvea. Acta Physiol Scand. 1968;73:511-522.
    • (1968) Acta Physiol Scand , vol.73 , pp. 511-522
    • Bill, A.1
  • 56
    • 28644432836 scopus 로고    scopus 로고
    • Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration
    • Amrite AC, Kompella UB. Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration. J Pharm Pharmacol. 2005;57:1555-1563.
    • (2005) J Pharm Pharmacol , vol.57 , pp. 1555-1563
    • Amrite, A.C.1    Kompella, U.B.2
  • 57
    • 33644673252 scopus 로고    scopus 로고
    • M cells in the follicle-associated epithelium of the rabbit conjunctiva preferentially bind and translocate latex beads
    • Liu H, Meagher CK, Moore CP, Phillips TE. M cells in the follicle-associated epithelium of the rabbit conjunctiva preferentially bind and translocate latex beads. Invest Ophthalmol Vis Sci. 2005;46:4217-4223.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4217-4223
    • Liu, H.1    Meagher, C.K.2    Moore, C.P.3    Phillips, T.E.4
  • 58
    • 33750602659 scopus 로고    scopus 로고
    • Bovine and porcine transscleral solute transport: Influence of lipophilicity and the choroid-Bruch's layer
    • Cheruvu NP, Kompella UB. Bovine and porcine transscleral solute transport: influence of lipophilicity and the choroid-Bruch's layer. Invest Ophthalmol Vis Sci. 2006;47:4513-4522.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 4513-4522
    • Cheruvu, N.P.1    Kompella, U.B.2
  • 59
    • 13944264268 scopus 로고    scopus 로고
    • Permeability of retinal pigment epithelium: Effects of permeant molecular weight and lipophilicity
    • Pitkanen L, Ranta VP, Moilanen H, Urtti A. Permeability of retinal pigment epithelium: effects of permeant molecular weight and lipophilicity. Invest Ophthalmol Vis Sci. 2005;46:641-646.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 641-646
    • Pitkanen, L.1    Ranta, V.P.2    Moilanen, H.3    Urtti, A.4
  • 60
    • 34250163534 scopus 로고    scopus 로고
    • Pharmacokinetics of intraocular drug delivery by periocular injections using ocular fluorophotometry
    • Ghate D, Brooks W, McCarey BE, Edelhauser HF. Pharmacokinetics of intraocular drug delivery by periocular injections using ocular fluorophotometry. Invest Ophthalmol Vis Sci. 2007;48:2230-2237.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 2230-2237
    • Ghate, D.1    Brooks, W.2    McCarey, B.E.3    Edelhauser, H.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.