Filter-cultured ARPE-19 cells as outer blood-retinal barrier model

European Journal of Pharmaceutical Sciences

Volumn 40, Issue 4, 2010, Pages 289-296

  Mannermaa, Eliisa ^a   Reinisalo, Mika ^a   Ranta, Veli Pekka ^a   Vellonen, Kati Sisko ^b   Kokki, Heidi ^a   Saarikko, Anni ^a   Kaarniranta, Kai ^a   Urtti, Arto ^b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Blood retinal barrier; Cell culture model; Ocular drug delivery; Ocular pharmacokinetics; Retinal pigment epithelium

Indexed keywords

6 CARBOXYFLUORESCEIN; BETAXOLOL; CYCLOSPORIN A; DIGOXIN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; FLUORESCEIN SODIUM; MESSENGER RNA; MONOPHENOL MONOOXYGENASE; PROTEIN CRALBP; PROTEIN MITF A; PROTEIN RPE65; PROTEIN TRP 1; PROTEIN VMD2; RHODAMINE 123; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR OTX2; UNCLASSIFIED DRUG; EYE PROTEIN; MELANIN;

ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CELL LINE; CELL STRAIN ARPE 19; CHOROID; CONTROLLED STUDY; COW; DIFFUSION; DRUG PENETRATION; DRUG TRANSPORT; FILTER; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MELANOGENESIS; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ACTIVE TRANSPORT; BIOSYNTHESIS; BLOOD RETINA BARRIER; CELL MEMBRANE PERMEABILITY; CELL POLARITY; CHEMICAL PHENOMENA; COMPARATIVE STUDY; DIFFUSION CHAMBER; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR WEIGHT; PHARMACOKINETICS;

BIOLOGICAL TRANSPORT, ACTIVE; BLOOD-RETINAL BARRIER; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL POLARITY; DIFFUSION CHAMBERS, CULTURE; EYE PROTEINS; GENE EXPRESSION; HUMANS; HYDROPHOBICITY; MELANINS; MOLECULAR WEIGHT; PHARMACOKINETICS; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS;

EID: 77953541928     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2010.04.001     Document Type: Article

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