메뉴 건너뛰기




Volumn 8, Issue 3, 2011, Pages 159-167

Mitochondria and the aging heart

Author keywords

Aging; Heart; Heart diseases; Mitochondria; Reactive oxygen species

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

EID: 80053553801     PISSN: 16715411     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1263.2011.00159     Document Type: Conference Paper
Times cited : (49)

References (106)
  • 1
    • 79954536346 scopus 로고    scopus 로고
    • accessed on September 15, 2011
    • Statistics-Canada. Mortality, Summary List of Causes. 2007. www.statcan.gc.ca/pub/84f0209x/84f0209x2007000-eng.htm (accessed on September 15, 2011).
    • (2007) Mortality, Summary List of Causes
  • 2
    • 0030779031 scopus 로고    scopus 로고
    • Myocardial injury after hypoxia in immature, adult and aged rats
    • Starnes JW, Bowles DK, Seiler KS. Myocardial injury after hypoxia in immature, adult and aged rats. Aging (Milano) 1997; 9: 268-276.
    • (1997) Aging (Milano) , vol.9 , pp. 268-276
    • Starnes, J.W.1    Bowles, D.K.2    Seiler, K.S.3
  • 3
    • 0028725260 scopus 로고
    • Aging increases ischemia- reperfusion injury in the isolated, buffer-perfused heart
    • Lesnefsky EJ, Gallo DS, Ye J, et al. Aging increases ischemia- reperfusion injury in the isolated, buffer-perfused heart. J Lab Clin Med 1994; 124: 843-851.
    • (1994) J Lab Clin Med , vol.124 , pp. 843-851
    • Lesnefsky, E.J.1    Gallo, D.S.2    Ye, J.3
  • 4
    • 80053462667 scopus 로고    scopus 로고
    • Aging might increase myocardial ischemia/reperfusion-induced apoptosis in humans and rats
    • In press
    • Liu M, Zhang P, Chen M, et al. Aging might increase myocardial ischemia/reperfusion-induced apoptosis in humans and rats. Age (Dordr) 2011; In press.
    • (2011) Age (Dordr)
    • Liu, M.1    Zhang, P.2    Chen, M.3
  • 5
    • 0033774930 scopus 로고    scopus 로고
    • Tolerance to ischemia and hypoxia is reduced in aged human myocardium
    • Mariani J, Ou R, Bailey M, et al. Tolerance to ischemia and hypoxia is reduced in aged human myocardium. J Thorac Cardiovasc Surg 2000; 120: 660-667.
    • (2000) J Thorac Cardiovasc Surg , vol.120 , pp. 660-667
    • Mariani, J.1    Ou, R.2    Bailey, M.3
  • 6
    • 0032588766 scopus 로고    scopus 로고
    • 10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: Studies in rats and in human atrial tissue
    • Rosenfeldt FL, Pepe S, Ou R, et al. Coenzyme Q10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: studies in rats and in human atrial tissue. Biofactors 1999; 9: 291-299. (Pubitemid 29289009)
    • (1999) BioFactors , vol.9 , Issue.2-4 , pp. 291-299
    • Rosenfeldt, F.L.1    Pepe, S.2    Ou, R.3    Mariani, J.A.4    Rowland, M.A.5    Nagley, P.6    Linnane, A.W.7
  • 8
    • 12244290334 scopus 로고    scopus 로고
    • Healthy ageing: A question of stress, damage and repair. Meeting on mechanisms of biology ageing
    • DOI 10.1093/embo-reports/kvf247
    • Jansen-Durr P, Osiewacz HD. Healthy ageing: a question of stress, damage and repair. Meeting on mechanisms of biological ageing. EMBO Rep 2002; 3: 1127-1132. (Pubitemid 36104999)
    • (2002) EMBO Reports , vol.3 , Issue.12 , pp. 1127-1132
    • Jansen-Durr, P.1    Osiewacz, H.D.2
  • 9
    • 0026541467 scopus 로고
    • Age-dependent sensitivity to unprotected cardiac ischemia: The senescent myocardium
    • Misare BD, Krukenkamp IB, Levitsky S. Age-dependent sensitivity to unprotected cardiac ischemia: the senescent myocardium. J Thorac Cardiovasc Surg 1992; 103: 60-64.
    • (1992) J Thorac Cardiovasc Surg , vol.103 , pp. 60-64
    • Misare, B.D.1    Krukenkamp, I.B.2    Levitsky, S.3
  • 10
    • 77955718033 scopus 로고    scopus 로고
    • Aging and heart failure: Changing demographics and implications for therapy in the elderly
    • Jugdutt BI. Aging and heart failure: changing demographics and implications for therapy in the elderly. Heart Fail Rev 2010; 15: 401-405.
    • (2010) Heart Fail Rev , vol.15 , pp. 401-405
    • Jugdutt, B.I.1
  • 11
    • 79955619877 scopus 로고    scopus 로고
    • Chronic heart failure in older adults
    • Ahmed A. Chronic heart failure in older adults. Med Clin North Am 2011; 95: 439-461.
    • (2011) Med Clin North Am , vol.95 , pp. 439-461
    • Ahmed, A.1
  • 12
    • 79751531393 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2011 update: A report from the American Heart Association
    • Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics - 2011 update: a report from the American Heart Association. Circulation 2011; 123: e18-e209.
    • (2011) Circulation , vol.123
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3
  • 14
    • 79960819370 scopus 로고    scopus 로고
    • Diastolic heart failure: Progress, treatment challenges, and prevention
    • Wood P, Piran S, Liu PP. Diastolic heart failure: progress, treatment challenges, and prevention. Can J Cardiol 2011; 27: 302-310.
    • (2011) Can J Cardiol , vol.27 , pp. 302-310
    • Wood, P.1    Piran, S.2    Liu, P.P.3
  • 15
    • 0037133660 scopus 로고    scopus 로고
    • New concepts in diastolic dysfunction and diastolic heart failure: Part I: Diagnosis, prognosis, and measurements of diastolic function
    • DOI 10.1161/hc1102.105289
    • Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure: Part I: diagnosis, prognosis, and measurements of diastolic function. Circulation 2002; 105: 1387-1393. (Pubitemid 34260433)
    • (2002) Circulation , vol.105 , Issue.11 , pp. 1387-1393
    • Zile, M.R.1    Brutsaert, D.L.2
  • 16
    • 79954611529 scopus 로고    scopus 로고
    • Congestive heart failure with preserved ejection fraction is associated with severely impaired dynamic Starling mechanism
    • Shibata S, Hastings JL, Prasad A, et al. Congestive heart failure with preserved ejection fraction is associated with severely impaired dynamic Starling mechanism. J Appl Physiol 2011; 110: 964-971.
    • (2011) J Appl Physiol , vol.110 , pp. 964-971
    • Shibata, S.1    Hastings, J.L.2    Prasad, A.3
  • 17
    • 23844536232 scopus 로고    scopus 로고
    • Views from within and beyond: Narratives of cardiac contractile dysfunction under senescence
    • DOI 10.1385/ENDO:26:2:127
    • Yang X, Sreejayan N, Ren J. Views from within and beyond: narratives of cardiac contractile dysfunction under senescence. Endocrine 2005; 26: 127-137. (Pubitemid 41271104)
    • (2005) Endocrine , vol.26 , Issue.2 , pp. 127-137
    • Yang, X.1    Sreejayan, N.2    Ren, J.3
  • 18
    • 33744456501 scopus 로고    scopus 로고
    • Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: Role of oxidative stress
    • Yang X, Doser TA, Fang CX, et al. Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress. FASEB J 2006; 20: 1024-1026.
    • (2006) FASEB J , vol.20 , pp. 1024-1026
    • Yang, X.1    Doser, T.A.2    Fang, C.X.3
  • 19
    • 78650835776 scopus 로고    scopus 로고
    • Impact of long-term caloric restriction on cardiac senescence: Caloric restriction ameliorates cardiac diastolic dysfunction associated with aging
    • Shinmura K, Tamaki K, Sano M, et al. Impact of long-term caloric restriction on cardiac senescence: caloric restriction ameliorates cardiac diastolic dysfunction associated with aging. J Mol Cell Cardiol 2011; 50: 117-127.
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 117-127
    • Shinmura, K.1    Tamaki, K.2    Sano, M.3
  • 20
    • 80053025054 scopus 로고    scopus 로고
    • Absence of meal-induced insulin sensitization (AMIS) in aging rats is associated with cardiac dysfunction that is protected by antioxidants
    • In press
    • Ming Z, Legare DJ, Lautt WW. Absence of meal-induced insulin sensitization (AMIS) in aging rats is associated with cardiac dysfunction that is protected by antioxidants. J Appl Physiol 2011; In press.
    • (2011) J Appl Physiol
    • Ming, Z.1    Legare, D.J.2    Lautt, W.W.3
  • 22
    • 70349729930 scopus 로고    scopus 로고
    • Diastolic dysfunction, cardiovascular aging, and the anesthesiologist
    • Sanders D, Dudley M, Groban L. Diastolic dysfunction, cardiovascular aging, and the anesthesiologist. Anesthesiol Clin 2009; 27: 497-517.
    • (2009) Anesthesiol Clin , vol.27 , pp. 497-517
    • Sanders, D.1    Dudley, M.2    Groban, L.3
  • 23
    • 74049135456 scopus 로고    scopus 로고
    • Effect of age on cardiac excitation-contraction coupling
    • Fares E, Howlett SE. Effect of age on cardiac excitation-contraction coupling. Clin Exp Pharmacol Physiol 2010; 37: 1-7.
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 1-7
    • Fares, E.1    Howlett, S.E.2
  • 25
    • 41149107026 scopus 로고    scopus 로고
    • Aging-Related Defects Are Associated With Adverse Cardiac Remodeling in a Mouse Model of Reperfused Myocardial Infarction
    • DOI 10.1016/j.jacc.2008.01.011, PII S0735109708003331
    • Bujak M, Kweon HJ, Chatila K, et al. Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol 2008; 51: 1384-1392. (Pubitemid 351443080)
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.14 , pp. 1384-1392
    • Bujak, M.1    Kweon, H.J.2    Chatila, K.3    Li, N.4    Taffet, G.5    Frangogiannis, N.G.6
  • 27
    • 0026351795 scopus 로고
    • Comparison of differences in the hemodynamic response to passive postural stress in healthy subjects greater than 70 years and less than 30 years of age
    • Shannon RP, Maher KA, Santinga JT, et al. Comparison of differences in the hemodynamic response to passive postural stress in healthy subjects greater than 70 years and less than 30 years of age. Am J Cardiol 1991; 67: 1110-1116.
    • (1991) Am J Cardiol , vol.67 , pp. 1110-1116
    • Shannon, R.P.1    Maher, K.A.2    Santinga, J.T.3
  • 28
    • 0028935470 scopus 로고
    • Impact of age on the cardiovascular response to dynamic upright exercise in healthy men and women
    • Fleg JL, O'Connor F, Gerstenblith G, et al. Impact of age on the cardiovascular response to dynamic upright exercise in healthy men and women. J Appl Physiol 1995; 78: 890-900.
    • (1995) J Appl Physiol , vol.78 , pp. 890-900
    • Fleg, J.L.1    O'Connor, F.2    Gerstenblith, G.3
  • 29
    • 79959523055 scopus 로고    scopus 로고
    • Effects of calorie restriction on cardioprotection and cardiovascular health
    • Ahmet I, Tae HJ, De Cabo R, et al. Effects of calorie restriction on cardioprotection and cardiovascular health. J Mol Cell Cardiol 2011; 51: 263-271.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 263-271
    • Ahmet, I.1    Tae, H.J.2    De Cabo, R.3
  • 31
    • 79956330068 scopus 로고    scopus 로고
    • Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy
    • Boyle AJ, Shih H, Hwang J, et al. Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. Exp Gerontol 2011; 46: 549-559.
    • (2011) Exp Gerontol , vol.46 , pp. 549-559
    • Boyle, A.J.1    Shih, H.2    Hwang, J.3
  • 32
    • 0027401286 scopus 로고
    • Heart rate variability and aerobic fitness
    • DOI 10.1016/0002-8703(93)90164-5
    • De Meersman RE. Heart rate variability and aerobic fitness. Am Heart J 1993; 125: 726-731. (Pubitemid 23079839)
    • (1993) American Heart Journal , vol.125 , Issue.3 , pp. 726-731
    • De Meersman, R.E.1
  • 33
    • 0043208996 scopus 로고    scopus 로고
    • The effect of age and gender on heart rate variability after endurance training
    • DOI 10.1249/01.MSS.0000079046.01763.8F
    • Carter JB, Banister EW, Blaber AP. The effect of age and gender on heart rate variability after endurance training. Med Sci Sports Exerc 2003; 35: 1333-1340. (Pubitemid 36936152)
    • (2003) Medicine and Science in Sports and Exercise , vol.35 , Issue.8 , pp. 1333-1340
    • Carter, J.B.1    Banister, E.W.2    Blaber, A.P.3
  • 34
    • 79956133768 scopus 로고    scopus 로고
    • Changes in heart rate variability associated with acute alcohol consumption: Current knowledge and implications for practice and research
    • Romanowicz M, Schmidt JE, Bostwick JM, et al. Changes in heart rate variability associated with acute alcohol consumption: current knowledge and implications for practice and research. Alcohol Clin Exp Res 2011; 35: 1092-1105.
    • (2011) Alcohol Clin Exp Res , vol.35 , pp. 1092-1105
    • Romanowicz, M.1    Schmidt, J.E.2    Bostwick, J.M.3
  • 35
    • 0028173027 scopus 로고
    • Age-associated changes in beta-adrenergic modulation on rat cardiac excitation-contraction coupling
    • Xiao RP, Spurgeon HA, O'Connor F, et al. Age-associated changes in beta-adrenergic modulation on rat cardiac excitation-contraction coupling. J Clin Invest 1994; 94: 2051-2059.
    • (1994) J Clin Invest , vol.94 , pp. 2051-2059
    • Xiao, R.P.1    Spurgeon, H.A.2    O'Connor, F.3
  • 36
    • 76049100055 scopus 로고    scopus 로고
    • Age-related left ventricular remodeling and associated risk for cardiovascular outcomes: The multi-ethnic study of atherosclerosis
    • Cheng S, Fernandes VR, Bluemke DA, et al. Age-related left ventricular remodeling and associated risk for cardiovascular outcomes: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Imaging 2009; 2: 191-198.
    • (2009) Circ Cardiovasc Imaging , vol.2 , pp. 191-198
    • Cheng, S.1    Fernandes, V.R.2    Bluemke, D.A.3
  • 37
    • 0025801813 scopus 로고
    • Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy
    • Olivetti G, Melissari M, Capasso JM, et al. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy. Circ Res 1991; 68: 1560-1568.
    • (1991) Circ Res , vol.68 , pp. 1560-1568
    • Olivetti, G.1    Melissari, M.2    Capasso, J.M.3
  • 39
    • 0026114977 scopus 로고
    • The aging of the heart: Weight and structural changes in the left ventricle with age
    • Melissari M, Balbi T, Gennari M, et al. The aging of the heart: weight and structural changes in the left ventricle with age. G Ital Cardiol 1991; 21: 119-130.
    • (1991) G Ital Cardiol , vol.21 , pp. 119-130
    • Melissari, M.1    Balbi, T.2    Gennari, M.3
  • 40
    • 0015888251 scopus 로고
    • Changes in the aging human heart. I. Heart weight in the aged
    • Linzbach AJ, Akuamoa-Boateng E. Changes in the aging human heart. I. Heart weight in the aged. Klin Wochenschr 1973; 51: 156-163.
    • (1973) Klin Wochenschr , vol.51 , pp. 156-163
    • Linzbach, A.J.1    Akuamoa-Boateng, E.2
  • 41
    • 0036890080 scopus 로고    scopus 로고
    • Left ventricular remodeling with age in normal men versus women: Novel insights using three-dimensional magnetic resonance imaging
    • DOI 10.1016/S0002-9149(02)02840-0, PII S0002914902028400
    • Hees PS, Fleg JL, Lakatta EG, et al. Left ventricular remodeling with age in normal men versus women: novel insights using three-dimensional magnetic resonance imaging. Am J Cardiol 2002; 90: 1231-1236. (Pubitemid 35346881)
    • (2002) American Journal of Cardiology , vol.90 , Issue.11 , pp. 1231-1236
    • Hees, P.S.1    Fleg, J.L.2    Lakatta, E.G.3    Shapiro, E.P.4
  • 42
    • 79551502051 scopus 로고    scopus 로고
    • The aging heart, myocardial fibrosis, and its relationship to circulating C-type natriuretic peptide
    • Sangaralingham SJ, Huntley BK, Martin FL, et al. The aging heart, myocardial fibrosis, and its relationship to circulating C-type natriuretic peptide. Hypertension 2011; 57: 201-207.
    • (2011) Hypertension , vol.57 , pp. 201-207
    • Sangaralingham, S.J.1    Huntley, B.K.2    Martin, F.L.3
  • 43
    • 0033852663 scopus 로고    scopus 로고
    • Connective tissue and the heart. Functional significance and regulatory mechanisms
    • Burlew BS, Weber KT. Connective tissue and the heart. Functional significance and regulatory mechanisms. Cardiol Clin 2000; 18: 435-442.
    • (2000) Cardiol Clin , vol.18 , pp. 435-442
    • Burlew, B.S.1    Weber, K.T.2
  • 44
    • 77955172516 scopus 로고    scopus 로고
    • Cardiomyogenesis in the adult human heart
    • Kajstura J, Urbanek K, Perl S, et al. Cardiomyogenesis in the adult human heart. Circ Res 107: 305-315.
    • Circ Res , vol.107 , pp. 305-315
    • Kajstura, J.1    Urbanek, K.2    Perl, S.3
  • 45
    • 64249107059 scopus 로고    scopus 로고
    • Evidence for cardiomyocyte renewal in humans
    • Bergmann O, Bhardwaj RD, Bernard S, et al. Evidence for cardiomyocyte renewal in humans. Science 2009; 324: 98-102.
    • (2009) Science , vol.324 , pp. 98-102
    • Bergmann, O.1    Bhardwaj, R.D.2    Bernard, S.3
  • 46
    • 74049135456 scopus 로고    scopus 로고
    • Effect of age on cardiac excitation-contraction coupling
    • Fares E, Howlett SE. Effect of age on cardiac excitation-contraction coupling. Clin Exp Pharmacol Physiol 2010; 37: 1-7.
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 1-7
    • Fares, E.1    Howlett, S.E.2
  • 47
    • 1242270679 scopus 로고    scopus 로고
    • Sarcolemmal K(ATP) channels in ageing
    • Jovanovic S, Jovanovic A. Sarcolemmal K(ATP) channels in ageing. Ageing Res Rev 2004; 3: 199-214.
    • (2004) Ageing Res Rev , vol.3 , pp. 199-214
    • Jovanovic, S.1    Jovanovic, A.2
  • 48
    • 0037204531 scopus 로고    scopus 로고
    • Ageing is associated with a decrease in the number of sarcolemmal ATP-sensitive K+ channels in a gender-dependent manner
    • Ranki HJ, Crawford RM, Budas GR, et al. Ageing is associated with a decrease in the number of sarcolemmal ATP-sensitive K+ channels in a gender-dependent manner. Mech Ageing Dev 2002; 123: 695- 705.
    • (2002) Mech Ageing Dev , vol.123 , pp. 695-705
    • Ranki, H.J.1    Crawford, R.M.2    Budas, G.R.3
  • 49
    • 69249219274 scopus 로고    scopus 로고
    • Nicorandil protects ATP-sensitive potassium channels against oxidation-induced dysfunction in cardiomyocytes of aging rats
    • Raveaud S, Verdetti J, Faury G. Nicorandil protects ATP-sensitive potassium channels against oxidation-induced dysfunction in cardiomyocytes of aging rats. Biogerontology 2009; 10: 537-547.
    • (2009) Biogerontology , vol.10 , pp. 537-547
    • Raveaud, S.1    Verdetti, J.2    Faury, G.3
  • 50
    • 33745274726 scopus 로고    scopus 로고
    • Mitochondria: Dynamic Organelles in Disease, Aging, and Development
    • DOI 10.1016/j.cell.2006.06.010, PII S0092867406007689
    • Chan DC. Mitochondria: dynamic organelles in disease, aging, and development. Cell 2006; 125: 1241-1252. (Pubitemid 43929096)
    • (2006) Cell , vol.125 , Issue.7 , pp. 1241-1252
    • Chan, D.C.1
  • 51
    • 79952266729 scopus 로고    scopus 로고
    • Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
    • Hafner AV, Dai J, Gomes AP, et al. Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy. Aging (Albany NY) 2010; 2: 914-923.
    • (2010) Aging (Albany NY) , vol.2 , pp. 914-923
    • Hafner, A.V.1    Dai, J.2    Gomes, A.P.3
  • 52
    • 0015319592 scopus 로고
    • The biologic clock: The mitochondria?
    • Harman D. The biologic clock: the mitochondria? J Am Geriatr Soc 1972; 20: 145-147.
    • (1972) J Am Geriatr Soc , vol.20 , pp. 145-147
    • Harman, D.1
  • 54
    • 0024541837 scopus 로고
    • Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
    • Linnane AW, Marzuki S, Ozawa T, et al. Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1989; 1: 642-645. (Pubitemid 19078788)
    • (1989) Lancet , vol.1 , Issue.8639 , pp. 642-645
    • Linnane, A.W.1    Marzuki, S.2    Ozawa, T.3    Tanaka, M.4
  • 58
    • 0021128369 scopus 로고
    • Age-dependent structural changes in the myocardium of rats. A quantitative light- and electron-microscopic study on the right and left chamber wall
    • DOI 10.1016/0047-6374(84)90080-0
    • Frenzel H, Feimann J. Age-dependent structural changes in the myocardium of rats: A quantitative light- and electron-microscopic study on the right and left chamber wall. Mech Ageing Dev 1984; 27: 29-41. (Pubitemid 14038221)
    • (1984) Mechanisms of Ageing and Development , vol.27 , Issue.1 , pp. 29-41
    • Frenzel, H.1    Feimann, J.2
  • 59
    • 80053558155 scopus 로고    scopus 로고
    • The importance of mitochondrial DNA in aging and cancer
    • Desler C, Marcker ML, Singh KK, et al. The importance of mitochondrial DNA in aging and cancer. J Aging Res 2011; 407536.
    • (2011) J Aging Res , pp. 407536
    • Desler, C.1    Marcker, M.L.2    Singh, K.K.3
  • 60
    • 70449724857 scopus 로고    scopus 로고
    • Mitochondrial OPA1, apoptosis, and heart failure
    • Chen L, Gong Q, Stice JP, et al. Mitochondrial OPA1, apoptosis, and heart failure. Cardiovasc Res 2009; 84: 91-99.
    • (2009) Cardiovasc Res , vol.84 , pp. 91-99
    • Chen, L.1    Gong, Q.2    Stice, J.P.3
  • 61
  • 62
    • 0014070709 scopus 로고
    • On the origin of mitosing cells
    • Sagan L. On the origin of mitosing cells. J Theor Biol 1967; 14: 255-274.
    • (1967) J Theor Biol , vol.14 , pp. 255-274
    • Sagan, L.1
  • 63
    • 0016830903 scopus 로고
    • Symbiotic theory of the origin of eukaryotic organelles; criteria for proof
    • Margulis L. Symbiotic theory of the origin of eukaryotic organelles; criteria for proof. Symp Soc Exp Biol 1975; (29): 21-38.
    • (1975) Symp Soc Exp Biol , Issue.29 , pp. 21-38
    • Margulis, L.1
  • 64
    • 0014736956 scopus 로고
    • Recombination of non-chromosomal genes in Chlamydomonas: Assortment of mitochondria and chloroplasts?
    • Margulis L. Recombination of non-chromosomal genes in Chlamydomonas: assortment of mitochondria and chloroplasts? J Theor Biol 1970; 26: 337-342.
    • (1970) J Theor Biol , vol.26 , pp. 337-342
    • Margulis, L.1
  • 65
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • DOI 10.1016/j.cell.2005.02.001
    • Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 2005; 120: 483-495. (Pubitemid 40269763)
    • (2005) Cell , vol.120 , Issue.4 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 66
    • 67349155990 scopus 로고    scopus 로고
    • Morphological dynamics of mitochondria - A special emphasis on cardiac muscle cells
    • Hom J, Sheu SS Morphological dynamics of mitochondria - A special emphasis on cardiac muscle cells. J Mol Cell Cardiol 2009; 46: 811-820.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 811-820
    • Hom, J.1    Sheu, S.S.2
  • 68
    • 0026587335 scopus 로고
    • Mitochondrial genetics: A paradigm for aging and degenerative diseases?
    • Wallace DC. Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science 1992; 256: 628-632.
    • (1992) Science , vol.256 , pp. 628-632
    • Wallace, D.C.1
  • 69
    • 77953507107 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in disease and aging
    • Wallace DC. Mitochondrial DNA mutations in disease and aging. Environ Mol Mutagen 2010; 51: 440-450.
    • (2010) Environ Mol Mutagen , vol.51 , pp. 440-450
    • Wallace, D.C.1
  • 70
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
    • DOI 10.1146/annurev.genet.39.110304.095751
    • Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 2005; 39: 359-407. (Pubitemid 43011120)
    • (2005) Annual Review of Genetics , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 71
    • 0023811053 scopus 로고
    • Normal oxidative damage to mitochondrial and nuclear DNA is extensive
    • Richter C, Park JW, Ames BN. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci USA 1988; 85: 6465-6467.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6465-6467
    • Richter, C.1    Park, J.W.2    Ames, B.N.3
  • 72
    • 0031032817 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
    • DOI 10.1073/pnas.94.2.514
    • Yakes FM, Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 1997; 94: 514-519. (Pubitemid 27053665)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.2 , pp. 514-519
    • Yakes, F.M.1    Van Houten, B.2
  • 73
    • 0029587469 scopus 로고
    • Molecular genetic aspects of human mitochondrial disorders
    • Larsson NG, Clayton DA. Molecular genetic aspects of human mitochondrial disorders. Annu Rev Genet 1995; 29: 151-178. (Pubitemid 26005340)
    • (1995) Annual Review of Genetics , vol.29 , pp. 151-178
    • Larsson, N.-G.1    Clayton, D.A.2
  • 74
    • 0036258718 scopus 로고    scopus 로고
    • Ageing muscle: Clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function
    • DOI 10.1016/S0960-8966(01)00332-7, PII S0960896601003327
    • Fayet G, Jansson M, Sternberg D, et al. Ageing muscle: clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function. Neuromuscul Disord 2002; 12: 484-493. (Pubitemid 34556709)
    • (2002) Neuromuscular Disorders , vol.12 , Issue.5 , pp. 484-493
    • Fayet, G.1    Jansson, M.2    Sternberg, D.3    Moslemi, A.-R.4    Blondy, P.5    Lombes, A.6    Fardeau, M.7    Oldfors, A.8
  • 75
    • 57349130113 scopus 로고    scopus 로고
    • A mitochondrial etiology of neurodegenerative diseases: Evidence from Parkinson's disease
    • Khusnutdinova E, Gilyazova I, Ruiz-Pesini E, et al. A mitochondrial etiology of neurodegenerative diseases: evidence from Parkinson's disease. Ann NY Acad Sci 2008; 1147: 1-20.
    • (2008) Ann NY Acad Sci , vol.1147 , pp. 1-20
    • Khusnutdinova, E.1    Gilyazova, I.2    Ruiz-Pesini, E.3
  • 78
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956; 11: 298-300.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 80
    • 0035989388 scopus 로고    scopus 로고
    • Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster
    • Sun J, Folk D, Bradley TJ, et al. Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics 2002; 161: 661-672. (Pubitemid 34705407)
    • (2002) Genetics , vol.161 , Issue.2 , pp. 661-672
    • Sun, J.1    Folk, D.2    Bradley, T.J.3    Tower, J.4
  • 82
    • 0028827252 scopus 로고
    • Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
    • Li Y, Huang TT, Carlson EJ, et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 1995; 11: 376-381.
    • (1995) Nat Genet , vol.11 , pp. 376-381
    • Li, Y.1    Huang, T.T.2    Carlson, E.J.3
  • 84
    • 0034602958 scopus 로고    scopus 로고
    • Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart
    • DOI 10.1074/jbc.275.5.3343
    • Barazzoni R, Short KR, Nair KS. Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart. J Biol Chem 2000; 275: 3343-3347. (Pubitemid 30083037)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.5 , pp. 3343-3347
    • Barazzoni, R.1    Short, K.R.2    Nair, K.S.3
  • 85
    • 0024580556 scopus 로고
    • Decline in skeletal muscle mitochondrial respiratory chain function: Possible factor in ageing
    • Trounce I, Byrne E, Marzuki S. Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing. Lancet 1989; 1: 637-639. (Pubitemid 19078786)
    • (1989) Lancet , vol.1 , Issue.8639 , pp. 637-639
    • Trounce, I.1    Byrne, E.2    Marzuki, S.3
  • 86
    • 6344278442 scopus 로고    scopus 로고
    • Mitochondrial DNA and aging
    • DOI 10.1042/CS20040148
    • Alexeyev MF, Ledoux SP, Wilson GL. Mitochondrial DNA and aging. Clin Sci (Lond) 2004; 107: 355-364. (Pubitemid 39389302)
    • (2004) Clinical Science , vol.107 , Issue.4 , pp. 355-364
    • Alexeyev, M.F.1    LeDoux, S.P.2    Wilson, G.L.3
  • 87
    • 0032504657 scopus 로고    scopus 로고
    • Role of mitochondria in oxidative stress and ageing
    • DOI 10.1016/S0005-2728(98)00120-0, PII S0005272898001200
    • Lenaz G. Role of mitochondria in oxidative stress and ageing. Biochim Biophys Acta 1998; 1366: 53-67. (Pubitemid 28467022)
    • (1998) Biochimica et Biophysica Acta - Bioenergetics , vol.1366 , Issue.1-2 , pp. 53-67
    • Lenaz, G.1
  • 89
    • 16344374718 scopus 로고    scopus 로고
    • Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition
    • DOI 10.1016/j.cardiores.2005.02.009
    • Di Lisa F, Bernardi P. Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition. Cardiovasc Res 2005; 66: 222-232. (Pubitemid 40471037)
    • (2005) Cardiovascular Research , vol.66 , Issue.2 , pp. 222-232
    • Di, L.F.1    Bernardi, P.2
  • 91
    • 77953809952 scopus 로고    scopus 로고
    • What are the sources of hydrogen peroxide production by heart mitochondria?
    • Grivennikova VG, Kareyeva AV, Vinogradov AD. What are the sources of hydrogen peroxide production by heart mitochondria? Biochim Biophys Acta 2010; 1797: 939-944.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 939-944
    • Grivennikova, V.G.1    Kareyeva, A.V.2    Vinogradov, A.D.3
  • 92
    • 80053523468 scopus 로고    scopus 로고
    • The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism
    • Desler C, Lykke A, Rasmussen LJ. The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism. J Nucleic Acids 2010; 701518.
    • (2010) J Nucleic Acids , pp. 701518
    • Desler, C.1    Lykke, A.2    Rasmussen, L.J.3
  • 94
    • 33750920827 scopus 로고    scopus 로고
    • A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria
    • DOI 10.1089/ars.2006.8.1651
    • Brady NR, Hamacher-Brady A, Westerhoff HV, et al. A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria. Antioxid Redox Signal 2006; 8: 1651-1665. (Pubitemid 44726339)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.9-10 , pp. 1651-1665
    • Brady, N.R.1    Hamacher-Brady, A.2    Westerhoff, H.V.3    Gottlieb, R.A.4
  • 95
    • 46749113468 scopus 로고    scopus 로고
    • The malonyl CoA axis as a potential target for treating ischaemic heart disease
    • DOI 10.1093/cvr/cvn130
    • Ussher JR, Lopaschuk GD. The malonyl CoA axis as a potential target for treating ischaemic heart disease. Cardiovasc Res 2008; 79: 259-268. (Pubitemid 351951618)
    • (2008) Cardiovascular Research , vol.79 , Issue.2 , pp. 259-268
    • Ussher, J.R.1    Lopaschuk, G.D.2
  • 96
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • DOI 10.1016/S1534-5807(04)00099-1, PII S1534580704000991
    • Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6: 463-477. (Pubitemid 38456176)
    • (2004) Developmental Cell , vol.6 , Issue.4 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 97
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • DOI 10.1126/science.290.5497.1717
    • Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000; 290: 1717-1721. (Pubitemid 32004796)
    • (2000) Science , vol.290 , Issue.5497 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 98
    • 38949099761 scopus 로고    scopus 로고
    • Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
    • Simonsen A, Cumming RC, Brech A, et al. Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy 2008; 4: 176-184. (Pubitemid 351231181)
    • (2008) Autophagy , vol.4 , Issue.2 , pp. 176-184
    • Simonsen, A.1    Cumming, R.C.2    Brech, A.3    Isakson, P.4    Schubert, D.R.5    Finley, K.D.6
  • 99
    • 33745192802 scopus 로고    scopus 로고
    • Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
    • Hara T, Nakamura K, Matsui M, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441: 885-889.
    • (2006) Nature , vol.441 , pp. 885-889
    • Hara, T.1    Nakamura, K.2    Matsui, M.3
  • 100
    • 33646800306 scopus 로고    scopus 로고
    • Loss of autophagy in the central nervous system causes neurodegeneration in mice
    • Komatsu M, Waguri S, Chiba T, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441: 880-884.
    • (2006) Nature , vol.441 , pp. 880-884
    • Komatsu, M.1    Waguri, S.2    Chiba, T.3
  • 101
    • 0001944263 scopus 로고    scopus 로고
    • How do intracellular proteolytic systems change with age?
    • Cuervo AM, Dice JF. How do intracellular proteolytic systems change with age? Front Biosci 1998; 3: D25-D43.
    • (1998) Front Biosci , vol.3
    • Cuervo, A.M.1    Dice, J.F.2
  • 102
    • 33745026738 scopus 로고    scopus 로고
    • Autophagy and aging: The importance of maintaining "clean" cells
    • Cuervo AM, Bergamini E, Brunk UT, et al. Autophagy and aging: the importance of maintaining "clean" cells. Autophagy 2005; 1: 131-140.
    • (2005) Autophagy , vol.1 , pp. 131-140
    • Cuervo, A.M.1    Bergamini, E.2    Brunk, U.T.3
  • 103
    • 67650868959 scopus 로고    scopus 로고
    • Mitochondrial dynamics in mammalian health and disease
    • Liesa M, Palacin M, Zorzano A. Mitochondrial dynamics in mammalian health and disease. Physiol Rev 2009; 89: 799-845.
    • (2009) Physiol Rev , vol.89 , pp. 799-845
    • Liesa, M.1    Palacin, M.2    Zorzano, A.3
  • 105
    • 77953733762 scopus 로고    scopus 로고
    • Mitochondrial energy metabolism and ageing
    • Bratic I, Trifunovic A. Mitochondrial energy metabolism and ageing. Biochim Biophys Acta 2010; 1797: 961-967.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 961-967
    • Bratic, I.1    Trifunovic, A.2
  • 106
    • 77955861146 scopus 로고    scopus 로고
    • Autophagy in health and disease. 5. Mitophagy as a way of life
    • Gottlieb RA, Carreira RS. Autophagy in health and disease. 5. Mitophagy as a way of life. Am J Physiol Cell Physiol 2010; 299: C203-C210.
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Gottlieb, R.A.1    Carreira, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.