메뉴 건너뛰기




Volumn 28, Issue 7, 1996, Pages 1463-1477

Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart

Author keywords

Heart failure; Hypertrophy; Mononucleated and multinucleated myocytes; Myocyte number; Myocyte size

Indexed keywords

AGING; ARTICLE; CELL DENSITY; CELL LOSS; CELL SIZE; CONTROLLED STUDY; FEMALE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART RIGHT VENTRICLE; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE SEPTUM; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MULTINUCLEAR CELL; PRIORITY JOURNAL;

EID: 0030198981     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0137     Document Type: Article
Times cited : (192)

References (47)
  • 1
    • 0002330596 scopus 로고
    • Polyploidization and augmentation of heart muscle cells during normal cardiac growth and in cardiac hypertrophy
    • Oberpriller JO, Oberpriller JO, Mauro A, eds. New York: Harwood Academic Publishers
    • ADLER CP, 1991. Polyploidization and augmentation of heart muscle cells during normal cardiac growth and in cardiac hypertrophy. In: Oberpriller JO, Oberpriller JO, Mauro A, eds. The Development and Regenerative Potential of Cardiac Muscle. New York: Harwood Academic Publishers, 227-252.
    • (1991) The Development and Regenerative Potential of Cardiac Muscle , pp. 227-252
    • Adler, C.P.1
  • 2
    • 0022648143 scopus 로고
    • Myocardial DNA content, ploidy levels and cell number in geriatric hearts: Post mortem examination of human myocardium in old age
    • ADLER CP, FRIEDBURG H, 1986. Myocardial DNA content, ploidy levels and cell number in geriatric hearts: post mortem examination of human myocardium in old age. J Mol Cell Cardiol 18: 39-53.
    • (1986) J Mol Cell Cardiol , vol.18 , pp. 39-53
    • Adler, C.P.1    Friedburg, H.2
  • 3
    • 0015241562 scopus 로고
    • Numerische hyperplasie der herzmuskelzellen bei herzhypertrophie
    • ADLER CP, SANDRITTER W, 1971. Numerische Hyperplasie der Herzmuskelzellen bei Herzhypertrophie. Dtsch Med Wochenschr 48: 1895-1897.
    • (1971) Dtsch Med Wochenschr , vol.48 , pp. 1895-1897
    • Adler, C.P.1    Sandritter, W.2
  • 4
    • 0025949929 scopus 로고
    • Myocyte mitotic division in the aging mammalian rat heart
    • ANVERSA P, FITZPATRICK D, ARGANI S, CAPASSO JM, 1991. Myocyte mitotic division in the aging mammalian rat heart. Circ Res 69: 1159-1165.
    • (1991) Circ Res , vol.69 , pp. 1159-1165
    • Anversa, P.1    Fitzpatrick, D.2    Argani, S.3    Capasso, J.M.4
  • 5
    • 0018848130 scopus 로고
    • Morphometric study of early postnatal development in the left and right ventricular myocardium of the rat. I. Hypertrophy, hyperplasia, and binucleation of myocytes
    • ANVERSA P, OLIVETTI G, LOUD AV, 1980. Morphometric study of early postnatal development in the left and right ventricular myocardium of the rat. I. Hypertrophy, hyperplasia, and binucleation of myocytes. Circ Res 46: 495-502.
    • (1980) Circ Res , vol.46 , pp. 495-502
    • Anversa, P.1    Olivetti, G.2    Loud, A.V.3
  • 10
    • 0014158464 scopus 로고
    • The nuclear patterns of the cardiac muscle fiber
    • BAROLDI G, FALZI G, LAMPERTICO P, 1967. The nuclear patterns of the cardiac muscle fiber. Cardiologia 16: 109-123.
    • (1967) Cardiologia , vol.16 , pp. 109-123
    • Baroldi, G.1    Falzi, G.2    Lampertico, P.3
  • 11
    • 0016625013 scopus 로고
    • Cardiac muscle cytoplasmic and nuclear development during canine neonatal growth
    • Roy PE, Harris P, eds. Baltimore: University Park Press
    • BISHOP SP, HINE P, 1975. Cardiac muscle cytoplasmic and nuclear development during canine neonatal growth. In: Roy PE, Harris P, eds. Recent Advances in Studies on Cardiac Structure and Metabolism. Baltimore: University Park Press, Vol 8, 77-98.
    • (1975) Recent Advances in Studies on Cardiac Structure and Metabolism. , vol.8 , pp. 77-98
    • Bishop, S.P.1    Hine, P.2
  • 12
    • 0018489920 scopus 로고
    • Regional myocyte size in normotensive and spontaneously hypertensive rats
    • BISHOP SP, OPARIL S, REYNOLDS R, DRUMMOND JL, 1979. Regional myocyte size in normotensive and spontaneously hypertensive rats. Hypertension 1: 378-383.
    • (1979) Hypertension , vol.1 , pp. 378-383
    • Bishop, S.P.1    Oparil, S.2    Reynolds, R.3    Drummond, J.L.4
  • 14
  • 15
    • 0026643971 scopus 로고
    • Mechanical performance of spared myocytes after acute myocardial infarction in rats: Effects of captopril treatment
    • CAPASSO JM, ANVERSA P, 1992. Mechanical performance of spared myocytes after acute myocardial infarction in rats: effects of captopril treatment. Am J Physiol 263: H841-H849.
    • (1992) Am J Physiol , vol.263
    • Capasso, J.M.1    Anversa, P.2
  • 16
    • 0016249413 scopus 로고
    • Number of nuclei in isolated myocardial cells of pigs
    • GRABNER W, PFITZER P, 1974. Number of nuclei in isolated myocardial cells of pigs. Virchows Arch B 15: 279-294.
    • (1974) Virchows Arch B , vol.15 , pp. 279-294
    • Grabner, W.1    Pfitzer, P.2
  • 18
    • 0014589017 scopus 로고
    • Biochemical correlates of cardiac hypertrophy: IV Observations on the cellular organization of growth during myocardial hypertrophy in the rat
    • GROVE D, ZAK R, NAIR KG, ASCHENBRENNER V, 1969. Biochemical correlates of cardiac hypertrophy: IV Observations on the cellular organization of growth during myocardial hypertrophy in the rat. Circ Res 25: 473-485.
    • (1969) Circ Res , vol.25 , pp. 473-485
    • Grove, D.1    Zak, R.2    Nair, K.G.3    Aschenbrenner, V.4
  • 19
    • 0011907241 scopus 로고
    • Quantitative histologische untersuchungen an wachsenden herzen
    • HORT W, 1953. Quantitative Histologische Untersuchungen an Wachsenden Herzen. Virchows Arch A 323: 223-242.
    • (1953) Virchows Arch A , vol.323 , pp. 223-242
    • Hort, W.1
  • 20
    • 0023901646 scopus 로고
    • Effect of age on myocardial adaptation to volume overload in the rat
    • ISOYAMA S, GROSSMAN W, WEI JY, 1988. Effect of age on myocardial adaptation to volume overload in the rat. J Clin Invest 81: 1850-1857.
    • (1988) J Clin Invest , vol.81 , pp. 1850-1857
    • Isoyama, S.1    Grossman, W.2    Wei, J.Y.3
  • 21
    • 0023200289 scopus 로고
    • Effect of age on the development of cardiac hypertrophy produced by aortic constriction in the rat
    • ISOYAMA S, WEI JY, IZUMO S, FORT P, SCHOEN FJ, GROSSMAN W, 1987. Effect of age on the development of cardiac hypertrophy produced by aortic constriction in the rat. Circ Res 61: 337-345.
    • (1987) Circ Res , vol.61 , pp. 337-345
    • Isoyama, S.1    Wei, J.Y.2    Izumo, S.3    Fort, P.4    Schoen, F.J.5    Grossman, W.6
  • 22
    • 0028006390 scopus 로고
    • Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats
    • KAJSTURA J, ZHANG X, REISS K, SZOKE E, LI P, LAGRASTA C, CHENG W, DARZYNKIEWICZ Z, OLIVETTI G, ANVERSA P, 1994. Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats. Circ Res 74: 383-400.
    • (1994) Circ Res , vol.74 , pp. 383-400
    • Kajstura, J.1    Zhang, X.2    Reiss, K.3    Szoke, E.4    Li, P.5    Lagrasta, C.6    Cheng, W.7    Darzynkiewicz, Z.8    Olivetti, G.9    Anversa, P.10
  • 23
    • 0028867399 scopus 로고
    • The cellular basis of pacing-induced dilated cardiomyopathy: Myocyte cell loss and myocyte cellular reactive hypertrophy
    • KAJSTURA J, ZHANG X, LIU Y, SZOKE E, CHENG W, OLIVETTI G, HINTZE TH, ANVERSA P, 1995. The cellular basis of pacing-induced dilated cardiomyopathy: myocyte cell loss and myocyte cellular reactive hypertrophy. Circulation 92: 2306-2317.
    • (1995) Circulation , vol.92 , pp. 2306-2317
    • Kajstura, J.1    Zhang, X.2    Liu, Y.3    Szoke, E.4    Cheng, W.5    Olivetti, G.6    Hintze, T.H.7    Anversa, P.8
  • 24
    • 0017717786 scopus 로고
    • The predominance of binucleation in isolated rat heart myocytes
    • KATZBERG AA, FARMER BB, HARRIS RA, 1977. The predominance of binucleation in isolated rat heart myocytes. Am J Anat 149: 489-500.
    • (1977) Am J Anat , vol.149 , pp. 489-500
    • Katzberg, A.A.1    Farmer, B.B.2    Harris, R.A.3
  • 26
    • 0345489065 scopus 로고
    • Heart failure from the point of view of quantitative anatomy
    • LINZBACH AJ, 1960. Heart failure from the point of view of quantitative anatomy. Am J Cardiol 5: 370-382.
    • (1960) Am J Cardiol , vol.5 , pp. 370-382
    • Linzbach, A.J.1
  • 27
    • 0001161283 scopus 로고
    • Density and composition of mammalian muscle
    • MENDEZ J, KEYS A, 1960. Density and composition of mammalian muscle. Metabolism 9: 184-188.
    • (1960) Metabolism , vol.9 , pp. 184-188
    • Mendez, J.1    Keys, A.2
  • 28
    • 0026742621 scopus 로고
    • Assessment of rejection in orthotopic human heart transplantation using proliferating cell nuclear antigen (PCNA) as an index of cell proliferation
    • MANN JM, JENNISON SH, MOSS E, DAVIES MJ, 1992. Assessment of rejection in orthotopic human heart transplantation using proliferating cell nuclear antigen (PCNA) as an index of cell proliferation. J Pathol 167: 385-389.
    • (1992) J Pathol , vol.167 , pp. 385-389
    • Mann, J.M.1    Jennison, S.H.2    Moss, E.3    Davies, M.J.4
  • 29
    • 0025801813 scopus 로고
    • Cardiomyopathy of the aging human heart: Myocyte loss and reactive cellular hypertrophy
    • OLIVETTI G, MELISSARI M, CAPASSO JM, ANVERSA P, 1991. Cardiomyopathy of the aging human heart: myocyte loss and reactive cellular hypertrophy. Circ Res 68: 1560-1568.
    • (1991) Circ Res , vol.68 , pp. 1560-1568
    • Olivetti, G.1    Melissari, M.2    Capasso, J.M.3    Anversa, P.4
  • 30
    • 85047680067 scopus 로고
    • Myocyte cellular hypertrophy is responsible for ventricular remodelling in the hypertrophied heart of middle aged individuals in the absence of cardiac failure
    • OLIVETTI G, MELISSARI M, BALBI T, QUAINI F, CIGOLA E, SONNENBLICK EH, ANVERSA P, 1994a. Myocyte cellular hypertrophy is responsible for ventricular remodelling in the hypertrophied heart of middle aged individuals in the absence of cardiac failure. Cardiovasc Res 28: 1199-1208.
    • (1994) Cardiovasc Res , vol.28 , pp. 1199-1208
    • Olivetti, G.1    Melissari, M.2    Balbi, T.3    Quaini, F.4    Cigola, E.5    Sonnenblick, E.H.6    Anversa, P.7
  • 31
    • 0028271093 scopus 로고
    • Myocyte nuclear and possible cellular hyperplasia contribute to ventricular remodeling in the hypertrophic senescent heart in humans
    • OLIVETTI G, MELISSARI M, BALBI T, QUAINI F, SONNENBLICK EH, ANVERSA P, 1994b. Myocyte nuclear and possible cellular hyperplasia contribute to ventricular remodeling in the hypertrophic senescent heart in humans. J Am Coll Cardiol 24: 140-149.
    • (1994) J Am Coll Cardiol , vol.24 , pp. 140-149
    • Olivetti, G.1    Melissari, M.2    Balbi, T.3    Quaini, F.4    Sonnenblick, E.H.5    Anversa, P.6
  • 33
    • 0013918636 scopus 로고
    • Mitotic cell division in postnatal cardiac growth
    • OVERY HR, PRIEST RE, 1966. Mitotic cell division in postnatal cardiac growth. Lab Invest 15: 1100-1103.
    • (1966) Lab Invest , vol.15 , pp. 1100-1103
    • Overy, H.R.1    Priest, R.E.2
  • 34
    • 0028088576 scopus 로고
    • End-stage cardiac failure in humans is coupled with the induction of proliferating cell nuclear antigen and nuclear mitotic division in ventricular myocytes
    • QUAINI F, CIGOLA E, LAGRASTA C, SACCANI G, QUAINI E, ROSSI C, OLIVETTI G, ANVERSA P, 1994. End-stage cardiac failure in humans is coupled with the induction of proliferating cell nuclear antigen and nuclear mitotic division in ventricular myocytes. Circ Res 75: 1050-1063.
    • (1994) Circ Res , vol.75 , pp. 1050-1063
    • Quaini, F.1    Cigola, E.2    Lagrasta, C.3    Saccani, G.4    Quaini, E.5    Rossi, C.6    Olivetti, G.7    Anversa, P.8
  • 35
    • 0002356589 scopus 로고
    • Assessment of cardiac growth
    • Zak R ed. New York: Raven Press Publishers
    • RAKUSAN K, 1984. Assessment of cardiac growth. In: Zak R ed. Growth of the heart in Health and Disease. New York: Raven Press Publishers, 25-40.
    • (1984) Growth of the Heart in Health and Disease , pp. 25-40
    • Rakusan, K.1
  • 37
    • 0028796215 scopus 로고
    • Fibroblast proliferation during myocardial development in the rat is regulated by insulin-like growth factor-1 receptors
    • REISS K, CHENG W, KAJSTURA J, SONNENBLICK EH, MEGGS LG, ANVERSA P, 1995. Fibroblast proliferation during myocardial development in the rat is regulated by insulin-like growth factor-1 receptors. Am J Physiol 269: H943-H951.
    • (1995) Am J Physiol , vol.269
    • Reiss, K.1    Cheng, W.2    Kajstura, J.3    Sonnenblick, E.H.4    Meggs, L.G.5    Anversa, P.6
  • 38
    • 0027292195 scopus 로고
    • 1 autocrine system, enhanced expression of late growth related genes, DNA synthesis and myocyte nuclear mitotic division in rats
    • 1 autocrine system, enhanced expression of late growth related genes, DNA synthesis and myocyte nuclear mitotic division in rats. Exp Cell Res 207: 348-360.
    • (1993) Exp Cell Res , vol.207 , pp. 348-360
    • Reiss, K.1    Kajstura, J.2    Capasso, J.M.3    Marino, T.A.4    Anversa, P.5
  • 39
    • 0028001448 scopus 로고
    • Acute myocardial infarction leads to upregulation of the IGF-1 autocrine system, DNA replication, and nuclear mitotic division in the remaining viable cardiac myocytes
    • REISS K, KAJSTURA J, ZHANG X, LI P, SZOKE E, OLIVETTI G, ANVERSA P, 1994. Acute myocardial infarction leads to upregulation of the IGF-1 autocrine system, DNA replication, and nuclear mitotic division in the remaining viable cardiac myocytes. Exp Cell Res 213: 463-472.
    • (1994) Exp Cell Res , vol.213 , pp. 463-472
    • Reiss, K.1    Kajstura, J.2    Zhang, X.3    Li, P.4    Szoke, E.5    Olivetti, G.6    Anversa, P.7
  • 40
    • 0015915831 scopus 로고
    • Die zahl der kerne in isolierten zellen des menschlichen myokards
    • SCHNEIDER R, PEITZER P, 1973. Die Zahl der Kerne in isolierten Zellen des menschlichen Myokards. Virchows Arch B 12: 238-258.
    • (1973) Virchows Arch B , vol.12 , pp. 238-258
    • Schneider, R.1    Peitzer, P.2
  • 42
    • 0026503396 scopus 로고
    • Age-related differences in the expression of proto-oncogene and contractile protein genes in response to pressure overload in the rat myocardium
    • TAKAHASHI T, SCHUNKERT H, ISOYAMA S, WEI JY, NADAL-GINARD B, GROSSMAN W, IZUMO S, 1992. Age-related differences in the expression of proto-oncogene and contractile protein genes in response to pressure overload in the rat myocardium. J Clin Invest 89: 939-946.
    • (1992) J Clin Invest , vol.89 , pp. 939-946
    • Takahashi, T.1    Schunkert, H.2    Isoyama, S.3    Wei, J.Y.4    Nadal-Ginard, B.5    Grossman, W.6    Izumo, S.7
  • 43
    • 0025829193 scopus 로고
    • Myocardial changes in pressure overload-induced left ventricular hypertrophy: A study on tissue composition, polyploidization and multinucleation
    • VLIEGEN HW, VAN DER LAARSE A, CORNELISSE CJ, EULDERINK F, 1991. Myocardial changes in pressure overload-induced left ventricular hypertrophy: a study on tissue composition, polyploidization and multinucleation. Eur Heart J 12: 488-494.
    • (1991) Eur Heart J , vol.12 , pp. 488-494
    • Vliegen, H.W.1    Van Der Laarse, A.2    Cornelisse, C.J.3    Eulderink, F.4
  • 44
    • 0018969926 scopus 로고
    • Some statistical methods useful in circulation research
    • WALLENSTEIN S, ZUCKER CL, FLEISS JL, 1980. Some statistical methods useful in circulation research. Circ Res 47: 1-9.
    • (1980) Circ Res , vol.47 , pp. 1-9
    • Wallenstein, S.1    Zucker, C.L.2    Fleiss, J.L.3
  • 45
    • 0014013557 scopus 로고
    • Das verhalten des myokards bei der experimentellen supravalvularen aortenstenose: Autoradiographische und elektronenmikroskopische untersuchungen an rattenherzen
    • WEGNER G, MOLBERT E, 1966. Das Verhalten des Myokards bei der experimentellen supravalvularen Aortenstenose: autoradiographische und elektronenmikroskopische Untersuchungen an Rattenherzen. Virchows Arch A Pathol Anat 341: 54-63.
    • (1966) Virchows Arch A Pathol Anat , vol.341 , pp. 54-63
    • Wegner, G.1    Molbert, E.2
  • 46
    • 0027117437 scopus 로고
    • Age and the cardiovascular system
    • WEI, JY, 1992. Age and the cardiovascular system. N Engl J Med 237: 1735-1739.
    • (1992) N Engl J Med , vol.237 , pp. 1735-1739
    • Wei, J.Y.1
  • 47
    • 0016250642 scopus 로고
    • Development and proliferative capacity of cardiac muscle cells
    • ZAK R, 1974. Development and proliferative capacity of cardiac muscle cells. Circ Res 35: 17-26.
    • (1974) Circ Res , vol.35 , pp. 17-26
    • Zak, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.