Nicorandil protects ATP-sensitive potassium channels against oxidation-induced dysfunction in cardiomyocytes of aging rats

Biogerontology

Volumn 10, Issue 5, 2009, Pages 537-547

  Raveaud, Stéphanie ^a,b,c   Verdetti, Jean ^a,b,c   Faury, Gilles ^a,b,c  

^a UNIV GRENOBLE ALPES   (France)

^b CEA GRENOBLE   (France)

^c INSERM   (France)

Author keywords

Aging; ATP dependent potassium channels; Cardiac myocytes; Cardiovascular system; Nicorandil; Oxidation

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; DITHIOTHREITOL; NICORANDIL;

AGE DISTRIBUTION; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVITY; CELL FUNCTION; CELL PROTECTION; CHANNEL GATING; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HEART MUSCLE CELL; LONG TERM CARE; LOW DRUG DOSE; NEWBORN; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PATCH CLAMP; PRIORITY JOURNAL; RAT; TREATMENT DURATION;

EID: 69249219274     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-008-9196-9     Document Type: Article

References (50)

1. Anversa P, Palackal T, Sonnenblick EH, Olivetti G, Meggs LG, Capasso JM (1990) Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart. Circ Res 67:871-885
2. Bernhard D, Laufer G (2008) The aging cardiomyocyte: A mini-review. Gerontology 54:24-31. doi: 10.1159/000113503
3. Besse S, Bulteau AL, Boucher F, Riou B, Swynghedauw B, de Leiris J (2006) Antioxidant treatment prevents cardiac protein oxidation after ischemia-reperfusion and improves myocardial function and coronary perfusion in senescent hearts. J Physiol Pharmacol 57:541-552
4. Bishop SP, Dillon D, Naftilan, Reynolds R (1980) Surface morphology of isolated cardiac myocytes from hypertrophied hearts of aging spontaneously hypertensive rats. Scan Electron Microsc (Pt 2):193-199
5. Chen F, Wetzel GT, Friedman WF, Klitzner TS (1992) ATP-sensitive potassium channels in neonatal and adult rabbit ventricular myocytes. Pediatr Res 32:230-235. doi: 10.1203/00006450-199208000-00021
6. Coetzee WA, Nakamura TY, Faivre JF (1995) Effects of thiol-modifying agents on K ATP channels in guinea pig ventricular cells. Am J Physiol 269:H1625-H1633
7. Dröge W (2002) Aging-related changes in the thiol/disulfide redox state: Implications for the use of thiol antioxidants. Exp Gerontol 37:1333-1345. doi: 10.1016/S0531-5565(02)00175-4
8. Dubus I, Samuel JL, Marotte F, Delcayre C, Rappaport L (1990) β-adrenergic agonists stimulate the synthesis of noncontractile but not contractile proteins in cultured myocytes isolated from adult rat heart. Circ Res 66:867-874
9. Flaherty JT (1989) Nitrate tolerance. A review of the evidence. Drugs 37:523-550. doi: 10.2165/00003495-198937040-00006
10. Fraticelli A, Josephson R, Danziger R, Lakata E, Surgeon H (1989) Morphologic and contractile characteristics of individual cardiac myocytes of rats from maturation to senescence. Am J Physiol 257:H259-H265
11. Garnier-Raveaud S, Faury G, Mazenot C, Cand F, Godin-Ribuot D, Verdetti J (2002) Highly protective effects of chronic oral administration of nicorandil on the heart of ageing rats. Clin Exp Pharmacol Physiol 29:441-448. doi: 10.1046/j.1440-1681.2002.03679.x
12. Gross GJ, Auchampach JA, Maruyama M, Warltier DC, Pieper GM (1992) Cardioprotective effects of nicorandil. J Cardiovasc Pharmacol 20(Suppl 3):S22-S28. doi: 10.1097/00005344-199206203-00006
13. Harman D (1983) Free radical theory of aging: Consequences of mitochondrial aging. Age (Omaha) 6:86-94. doi: 10.1007/BF02432509
14. + channel in the mitochondrial inner membrane. Nature 352:244-247. doi: 10.1038/352244a0
15. Iwaki K, Sukhatme VP, Shubeita HE, Chien KR (1990) Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response. J Biol Chem 265:13809-13817
16. Jennings RB, Steenbergen C (1985) Nucleotide metabolism and cellular damage in myocardial ischemia. Annu Rev Physiol 47:727-749. doi: 10.1146/ annurev.ph.47.030185.003455
17. Jullien T, Cand F, Fargier C, Verdetti J (1989) Age-dependent differences in energetic status, electrical and mechanical performance of rat myocardium. Mech Ageing Dev 48:243-254. doi: 10.1016/ 0047-6374(89)90086-9
18. + channel in the rabbit portal vein. J Physiol 444:397-418
19. Kajioka S, Oike M, Kitamura K (1990) Nicorandil opens a calcium-dependent potassium channel in smooth muscle cells of the rat portal vein. J Pharmacol Exp Ther 254:905-913
20. Kakei M, Noma A, Shibasaki T (1985) Properties of adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells. J Physiol 363:441-462
21. Klima M, Burns TR, Chopra A (1990) Myocardial fibrosis in the elderly. Arch Pathol Lab Med 114:938-942
22. Kreye VA, Lenz T, Pfründer D, Theiss U (1992) Pharmacological characterization of nicorandil by 86Rb efflux and isometric vasorelaxation studies in vascular smooth muscle. J Cardiovasc Pharmacol 20(suppl 3):S8-S12. doi: 10.1097/00005344-199206203-00003
23. Krombach GA, Higgins CB, Chujo M, Saeed M (2005) Gadomer-enhanced MR imaging in the detection of microvascular obstruction: Alleviation with nicorandil therapy. Radiology 236:510-518. doi: 10.1148/radiol.2362030847
24. Kukovetz WR, Holzmann S, Poch G (1992) Molecular mechanism of action of nicorandil. J Cardiovasc Pharmacol 20:S1-S7. doi: 10.1097/ 00005344-199206203-00002
25. Lakatta EG (1987) Cardiac muscle changes in senescence. Annu Rev Physiol 49:519-531. doi: 10.1146/annurev.ph.49.030187.002511
26. Lu C, Minatoguchi S, Arai M, Wang N, Chen XH, Bao N, Kawamura I, Yasuda S, Kobayashi H, Wu DJ, Takemura G, Fujiwara H (2006) Nicorandil improves post-ischemic myocardial dysfunction in association with opening the mitochondrial K(ATP) channels and decreasing hydroxyl radicals in isolated rat hearts. Circ J 70:1650-1654. doi: 10.1253/circj.70.1650
27. Mano T, Shinohara R, Nagasaka A, Nakagawa H, Uchimura K, Hayashi R, Nakano I, Tsugawa T, Watanabe F, Kobayashi T, Fujiwara K, Nakai A, Itoh M (2000) Scavenging effect of nicorandil on free radicals and lipid peroxide in streptozotocin-induced diabetic rats. Metabolism 49:427-431. doi: 10.1016/S0026-0495(00)80003-7
28. Miki T, Seino S (2005) Roles of KATP channels as metabolic sensors in acute metabolic changes. J Mol Cell Cardiol 38:917-925. doi: 10.1016/ j.yjmcc.2004.11.019
29. Naito A, Aniya Y, Sakanashi M (1994) Antioxidative action of the nitrovasodilator nicorandil: Inhibition of oxidative activation of liver microsomal glutathione S-transferase and lipid peroxidation. Jpn J Pharmacol 65:209-213. doi: 10.1254/jjp.65.209
30. Nelson MT, Quayle JM (1995) Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 268:C799-C822
31. + channels in cardiac muscle. Nature 305:147-148. doi: 10.1038/305147a0
32. Noma A, Shibasaki T (1985) Membrane current through adenosine-triphosphate-reulated potassium channels in guinea pig ventricular cells. J Physiol 363:463-480
33. O'Neill L, Holbrook NJ, Lakatta EG (1991) Progressive changes from young adult age to senescence in mRNA for rat cardiac myosin heavy chain genes. Cardioscience 2:1-5
34. Ozcan C, Terzic A, Bienengraeber M (2007) Effective pharmacotherapy against oxidative injury: Alternative utility of an ATP-sensitive potassium channel opener. J Cardiovasc Pharmacol 50:411-418
35. Pieper GM, Gross GJ (1992) Anti-free-radical and neutrophil-modulating properties of the nitrovasodilator, nicorandil. Cardiovasc Drugs Ther 6:225-232. doi: 10.1007/BF00051143
36. Pinson A, Frelin C, Padieu P (1973) The lipoprotein lipase activity in cultured beating heart cells of the post-natal rat. Biochimie 55:1261-1264. doi: 10.1016/S0300-9084(74)80331-7
37. Pollesello P, Mebazaa A (2004) ATP-dependent potassium channels as a key target for the treatment of myocardial and vascular dysfunction. Curr Opin Crit Care 10:436-441. doi: 10.1097/01.ccx.0000145099.20822.19
38. Robert L (1999) Management of time by the cell and by the organism. J Soc Biol 193:401-410
39. Sato T, Sasaki N, O'Rourke B, Marban E (2000) Nicorandil, a potent cardioprotective agent, acts by opening mitochondrial ATP-dependent potassium channels. J Am Coll Cardiol 35:514-518. doi: 10.1016/ S0735-1097(99)00552-5
40. Seino S (1999) ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/receptor asssemblies. Annu Rev Physiol 61:337-362. doi: 10.1146/annurev.physiol.61.1.337
41. Szewczyk A, Wojcik G, Lobanov NA, Nalecz MJ (1999) Modification of the mitochondrial sulfonylurea receptor by thiol reagents. Biochem Biophys Res Commun 262:255-258. doi: 10.1006/bbrc.1999.1190
42. Shetty K (1994) Prescribing for angina. Practitioner 238:540-542
43. Swynghedauw B (2006) Phenotypic plasticity of adult myocardium: molecular mechanisms. J Exp Biol 209:2320-2327. doi: 10.1242/jeb.02084
44. Taira N (1989) Nicorandil as a hybrid between nitrates and potassium channel activators. Am J Cardiol 63:18J-24J. doi: 10.1016/ 0002-9149(89)90200-2
45. + channels of skeletal muscle fibers from young adult and aged rats: possible involvement of thiol-dependent redox mechanisms in the age-related modifications of their biophysical and pharmacological properties. Mol Pharmacol 46:754-761
46. Tricarico D, Petruzzi R, Conte Camerino D (1997) Different sulfonylurea and ATP sensitivity characterizes the juvenile and the adult form of K ATP channel complex of rat skeletal muscle. Eur J Pharmacol 321:369-378. doi: 10.1016/S0014-2999(96)00965-X
47. Trongvanichnam K, Mitsui-Saito M, Ozaki H, Karaki H (1996) Effects of chronic oral administration of a high dose of nicorandil on in vitro contractility of rat arterial smooth muscle. Eur J Pharmacol 314:83-90. doi: 10.1016/S0014-2999(96)00536-5
48. Tsujimoto G, Lee CH, Hoffman BB (1986) Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation. J Pharmacol Exp Ther 239:411-415
49. Wagner G (1992) Selected issues from an overview on nicorandil: tolerance, duration of action, and long-term efficacy. J Cardiovasc Pharmacol 20:86-92. doi: 10.1097/00005344-199206203-00015
50. Yanagisawa T, Satoh K, Taira N (1979) Circumstantial evidence for increased potassium conductance of membrane of cardiac muscle by-2-nicotinamidoethyl nitrate (SG-75). Jpn J Pharmacol 29:687-694. doi: 10.1254/jjp.29.687