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Volumn , Issue , 2012, Pages

Targeting the tumor microenvironment: Focus on angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; AXITINIB; BEVACIZUMAB; BORTEZOMIB; CEDIRANIB; CETUXIMAB; EVEROLIMUS; ICRUCUMAB; IMC 1121 B; IMC 18 F; LAPATINIB; LENALIDOMIDE; PANITUMUMAB; PAZOPANIB; POMALIDOMIDE; RAMUCIRUMAB; SORAFENIB; SUNITINIB; TAMOXIFEN; TAMOXIFEN CITRATE; TEMSIROLIMUS; THALIDOMIDE; TRASTUZUMAB; UNCLASSIFIED DRUG; VANDETANIB; VATALANIB;

EID: 80053483270     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2012/281261     Document Type: Review
Times cited : (101)

References (208)
  • 1
    • 79953158399 scopus 로고    scopus 로고
    • Exploring the genomes of cancer cells: Progress and promise
    • Stratton M. R., Exploring the genomes of cancer cells: progress and promise Science 2011 331 6024 1553 1558
    • (2011) Science , vol.331 , Issue.6024 , pp. 1553-1558
    • Stratton, M.R.1
  • 2
    • 0037079003 scopus 로고    scopus 로고
    • Rules for making human tumor cells
    • DOI 10.1056/NEJMra021902
    • Hahn W. C., Weinberg R. A., Rules for making human tumor cells The New England Journal of Medicine 2002 347 20 1593 1603 (Pubitemid 35315841)
    • (2002) New England Journal of Medicine , vol.347 , Issue.20 , pp. 1593-1603
    • Hahn, W.C.1    Weinberg, R.A.2
  • 3
    • 14644443626 scopus 로고    scopus 로고
    • The promise of genetically engineered mice for cancer prevention studies
    • DOI 10.1038/nrc1565
    • Green J. E., Hudson T., The promise of genetically engineered mice for cancer prevention studies Nature Reviews Cancer 2005 5 3 184 198 (Pubitemid 40314950)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.3 , pp. 184-198
    • Green, J.E.1    Hudson, T.2
  • 6
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A., Esteller M., Epigenetic modifications and human disease Nature Biotechnology 2010 28 10 1057 1068
    • (2010) Nature Biotechnology , vol.28 , Issue.10 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 7
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D., Weinberg R. A., Hallmarks of cancer: the next generation Cell 2011 144 5 646 674
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 79952392467 scopus 로고    scopus 로고
    • Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
    • Bissell M. J., Hines W. C., Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression Nature Medicine 2011 17 3 320 329
    • (2011) Nature Medicine , vol.17 , Issue.3 , pp. 320-329
    • Bissell, M.J.1    Hines, W.C.2
  • 9
    • 0030051051 scopus 로고    scopus 로고
    • Cellular changes involved in conversion of normal to malignant breast: Importance of the stromal reaction
    • Ronnov-Jessen L., Petersen O. W., Bissell M. J., Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction Physiological Reviews 1996 76 1 69 125 (Pubitemid 26048279)
    • (1996) Physiological Reviews , vol.76 , Issue.1 , pp. 69-125
    • Ronnov-Jessen, L.1    Petersen, O.W.2    Bissell, M.J.3
  • 10
    • 34548268026 scopus 로고    scopus 로고
    • Modelling breast cancer: One size does not fit all
    • DOI 10.1038/nrc2193, PII NRC2193
    • Vargo-Gogola T., Rosen J. M., Modelling breast cancer: one size does not fit all Nature Reviews Cancer 2007 7 9 659 672 (Pubitemid 47327411)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.9 , pp. 659-672
    • Vargo-Gogola, T.1    Rosen, J.M.2
  • 11
    • 34548462626 scopus 로고    scopus 로고
    • Mechanisms of Disease: Angiogenesis and the management of breast cancer
    • DOI 10.1038/ncponc0905, PII NCPONC0905
    • Banerjee S., Dowsett M., Ashworth A., Martin L. A., Mechanisms of disease: angiogenesis and the management of breast cancer Nature Clinical Practice Oncology 2007 4 9 536 550 (Pubitemid 47351464)
    • (2007) Nature Clinical Practice Oncology , vol.4 , Issue.9 , pp. 536-550
    • Banerjee, S.1    Dowsett, M.2    Ashworth, A.3    Martin, L.-A.4
  • 12
    • 58249101211 scopus 로고    scopus 로고
    • Bone marrow microenvironment and the identification of new targets for myeloma therapy
    • Podar K., Chauhan D., Anderson K. C., Bone marrow microenvironment and the identification of new targets for myeloma therapy Leukemia 2009 23 1 10 24
    • (2009) Leukemia , vol.23 , Issue.1 , pp. 10-24
    • Podar, K.1    Chauhan, D.2    Anderson, K.C.3
  • 14
    • 84964178914 scopus 로고
    • The growth of malignant disease in man and the lower animals, with special reference to the vascular system
    • Goldmann E., The growth of malignant disease in man and the lower animals, with special reference to the vascular system Proceedings of the Royal Society of Medicine 1908 1 1 13
    • (1908) Proceedings of the Royal Society of Medicine , vol.1 , pp. 1-13
    • Goldmann, E.1
  • 15
    • 0000970685 scopus 로고
    • Transplantability of tissues to the embryo of foreign species: Its bearing on questions of tissue specificity and tumor immunity
    • Murphy J. B., Transplantability of tissues to the embryo of foreign species: its bearing on questions of tissue specificity and tumor immunity Journal of Experimental Medicine 1913 17 4 482 493
    • (1913) Journal of Experimental Medicine , vol.17 , Issue.4 , pp. 482-493
    • Murphy, J.B.1
  • 16
    • 0002227026 scopus 로고
    • Angiogenesis in the early human chorion and in the primary placenta of the macaque monkey
    • Hertig A. T., Angiogenesis in the early human chorion and in the primary placenta of the macaque monkey Contributions to Embryology 1935 25 37 81
    • (1935) Contributions to Embryology , vol.25 , pp. 37-81
    • Hertig, A.T.1
  • 17
    • 0000912662 scopus 로고
    • Vascularization of the Brown Pearce rabbit epithelioma tranplant as seen in the transparent ear chamber
    • Ide A. G., Baker N. H., Warren S. L., Vascularization of the Brown Pearce rabbit epithelioma tranplant as seen in the transparent ear chamber American Journal of Roentgenology 1939 42 891 899
    • (1939) American Journal of Roentgenology , vol.42 , pp. 891-899
    • Ide, A.G.1    Baker, N.H.2    Warren, S.L.3
  • 18
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J., Tumor angiogenesis: therapeutic implications The New England Journal of Medicine 1971 285 21 1182 1186
    • (1971) The New England Journal of Medicine , vol.285 , Issue.21 , pp. 1182-1186
    • Folkman, J.1
  • 19
    • 0024384470 scopus 로고
    • Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
    • DOI 10.1016/0006-291X(89)92678-8
    • Ferrara N., Henzel W. J., Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells Biochemical and Biophysical Research Communications 1989 161 2 851 858 (Pubitemid 19162712)
    • (1989) Biochemical and Biophysical Research Communications , vol.161 , Issue.2 , pp. 851-858
    • Ferrara, N.1    Henzel, W.J.2
  • 21
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger D. R., Galli S. J., Dvorak A. M., Perruzzi C. A., Susan Harvey V., Dvorak H. F., Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid Science 1983 219 4587 983 985
    • (1983) Science , vol.219 , Issue.4587 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Susan Harvey, V.5    Dvorak, H.F.6
  • 22
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung D. W., Cachianes G., Kuang W. J., Goeddel D. V., Ferrara N., Vascular endothelial growth factor is a secreted angiogenic mitogen Science 1989 246 4935 1306 1309 (Pubitemid 20066716)
    • (1989) Science , vol.246 , Issue.4935 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.-J.3    Goeddel, D.V.4    Ferrara, N.5
  • 23
    • 0024801035 scopus 로고
    • Vascular permeability factor, an endothelial cell mitogen related to PDGF
    • Keck P. J., Hauser S. D., Krivi G., Sanzo K., Warren T., Feder J., Connolly D. T., Vascular permeability factor, an endothelial cell mitogen related to PDGF Science 1989 246 4935 1309 1312 (Pubitemid 20066717)
    • (1989) Science , vol.246 , Issue.4935 , pp. 1309-1312
    • Keck, P.J.1    Hauser, S.D.2    Krivi, G.3    Sanzo, K.4    Warren, T.5    Feder, J.6    Connolly, D.T.7
  • 24
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • DOI 10.1016/S0092-8674(00)80108-7
    • Hanahan D., Folkman J., Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 1996 86 3 353 364 (Pubitemid 26272076)
    • (1996) Cell , vol.86 , Issue.3 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 25
    • 47949089077 scopus 로고    scopus 로고
    • VEGF-targeted therapy: Mechanisms of anti-tumour activity
    • Ellis L. M., Hicklin D. J., VEGF-targeted therapy: mechanisms of anti-tumour activity Nature Reviews Cancer 2008 8 8 579 591
    • (2008) Nature Reviews Cancer , vol.8 , Issue.8 , pp. 579-591
    • Ellis, L.M.1    Hicklin, D.J.2
  • 26
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R. A., The hallmarks of cancer Cell 2000 100 1 57 70 (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 27
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes - Bipolar effects of the tumour stroma in cancer
    • DOI 10.1038/nrc1477
    • Mueller M. M., Fusenig N. E., Friends or foesbipolar effects of the tumour stroma in cancer Nature Reviews Cancer 2004 4 11 839 849 (Pubitemid 39472951)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.11 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 29
    • 77953988924 scopus 로고    scopus 로고
    • Targeting the tumour vasculature: Insights from physiological angiogenesis
    • Chung A. S., Lee J., Ferrara N., Targeting the tumour vasculature: insights from physiological angiogenesis Nature Reviews Cancer 2010 10 7 505 514
    • (2010) Nature Reviews Cancer , vol.10 , Issue.7 , pp. 505-514
    • Chung, A.S.1    Lee, J.2    Ferrara, N.3
  • 30
    • 77957241701 scopus 로고    scopus 로고
    • Dynamics of endothelial cell behavior in sprouting angiogenesis
    • Eilken H. M., Adams R. H., Dynamics of endothelial cell behavior in sprouting angiogenesis Current Opinion in Cell Biology 2010 22 5 617 625
    • (2010) Current Opinion in Cell Biology , vol.22 , Issue.5 , pp. 617-625
    • Eilken, H.M.1    Adams, R.H.2
  • 34
    • 0032886483 scopus 로고    scopus 로고
    • Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels
    • Yang S., Graham J., Kahn J. W., Schwartz E. A., Gerritsen M. E., Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels American Journal of Pathology 1999 155 3 887 895 (Pubitemid 29426835)
    • (1999) American Journal of Pathology , vol.155 , Issue.3 , pp. 887-895
    • Yang, S.1    Graham, J.2    Kahn, J.W.3    Schwartz, E.A.4    Gerritsen, M.E.5
  • 37
    • 0036831559 scopus 로고    scopus 로고
    • Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
    • DOI 10.1038/nrc925
    • Rafii S., Lyden D., Benezra R., Hattori K., Heissig B., Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? Nature Reviews Cancer 2002 2 11 826 835 (Pubitemid 37328901)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.11 , pp. 826-835
    • Rafii, S.1    Lyden, D.2    Benezra, R.3    Hattori, K.4    Heissig, B.5
  • 43
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • DOI 10.1038/nrc1093
    • Bergers G., Benjamin L. E., Tumorigenesis and the angiogenic switch Nature Reviews Cancer 2003 3 6 401 410 (Pubitemid 37328844)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 48
    • 33745303045 scopus 로고    scopus 로고
    • Hypoxia signalling in cancer and approaches to enforce tumour regression
    • DOI 10.1038/nature04871, PII NATURE04871
    • Pouysségur J., Dayan F., Mazure N. M., Hypoxia signalling in cancer and approaches to enforce tumour regression Nature 2006 441 7092 437 443 (Pubitemid 44050138)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 437-443
    • Pouyssegur, J.1    Dayan, F.2    Mazure, N.M.3
  • 50
    • 78049442966 scopus 로고    scopus 로고
    • The cellular response to hypoxia: Tuning the system with microRNAs
    • Loscalzo J., The cellular response to hypoxia: tuning the system with microRNAs Journal of Clinical Investigation 2010 120 11 3815 3817
    • (2010) Journal of Clinical Investigation , vol.120 , Issue.11 , pp. 3815-3817
    • Loscalzo, J.1
  • 51
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza G. L., Targeting HIF-1 for cancer therapy Nature Reviews Cancer 2003 3 10 721 732 (Pubitemid 37328811)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.10 , pp. 721-732
    • Semenza, G.L.1
  • 52
    • 77953597349 scopus 로고    scopus 로고
    • A therapeutic role for targeting c-Myc/Hif-1-dependent signaling pathways
    • Podar K., Anderson K. C., A therapeutic role for targeting c-Myc/Hif-1-dependent signaling pathways Cell Cycle 2010 9 9 1722 1728
    • (2010) Cell Cycle , vol.9 , Issue.9 , pp. 1722-1728
    • Podar, K.1    Anderson, K.C.2
  • 53
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon E. R., Vogelstein B., A genetic model for colorectal tumorigenesis Cell 1990 61 5 759 767
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 54
    • 80053477664 scopus 로고    scopus 로고
    • Differential colorectal carcinogenesis: Molecular basis and clinical relevance
    • Moran A., Ortega P, de Juan C., Differential colorectal carcinogenesis: molecular basis and clinical relevance World Journal of Gastrointestinal Oncology 2010 2 3 151 158
    • (2010) World Journal of Gastrointestinal Oncology , vol.2 , Issue.3 , pp. 151-158
    • Moran, A.1    Ortega, P.2    De Juan, C.3
  • 55
    • 0033119572 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase
    • Wang D., Huang H. J. S., Kazlauskas A., Cavenee W. K., Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase Cancer Research 1999 59 7 1464 1472 (Pubitemid 29160112)
    • (1999) Cancer Research , vol.59 , Issue.7 , pp. 1464-1472
    • Wang, D.1    Huang, H.-J.S.2    Kazlauskas, A.3    Cavenee, W.K.4
  • 57
    • 0001223491 scopus 로고    scopus 로고
    • Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
    • Viloria Petit A. M., Rak J., Hung M. C., Rockwell P., Goldstein N., Fendly B., Kerbel R. S., Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors American Journal of Pathology 1997 151 6 1523 1530 (Pubitemid 27527914)
    • (1997) American Journal of Pathology , vol.151 , Issue.6 , pp. 1523-1530
    • Viloria Petit, A.M.1    Rak, J.2    Hung, M.-C.3    Rockwell, P.4    Goldstein, N.5    Fendly, B.6    Kerbel, R.S.7
  • 58
    • 0033665761 scopus 로고    scopus 로고
    • Pre-operative serum vascular endothelial growth factor can select patients for adjuvant treatment after curative resection in colorectal cancer
    • Chin K. F., Greenman J., Gardiner E., Kumar H., Topping K., Monson J., Pre-operative serum vascular endothelial growth factor can select patients for adjuvant treatment after curative resection in colorectal cancer British Journal of Cancer 2000 83 11 1425 1431
    • (2000) British Journal of Cancer , vol.83 , Issue.11 , pp. 1425-1431
    • Chin, K.F.1    Greenman, J.2    Gardiner, E.3    Kumar, H.4    Topping, K.5    Monson, J.6
  • 59
    • 0032402444 scopus 로고    scopus 로고
    • Clinical significance of plasma vascular endothelial growth factor in gastrointestinal cancer
    • DOI 10.1016/S0959-8049(98)00282-2, PII S0959804998002822
    • Hyodo I., Doi T., Endo H., Hosokawa Y., Nishikawa Y., Tanimizu M., Jinno K., Kotani Y., Clinical significance of plasma vascular endothelial growth factor in gastrointestinal cancer European Journal of Cancer 1998 34 13 2041 2045 (Pubitemid 28546939)
    • (1998) European Journal of Cancer , vol.34 , Issue.13 , pp. 2041-2045
    • Hyodo, I.1    Doi, T.2    Endo, H.3    Hosokawa, Y.4    Nishikawa, Y.5    Tanimizu, M.6    Jinno, K.7    Kotani, Y.8
  • 60
    • 0032412517 scopus 로고    scopus 로고
    • Significance of angiogenic factors in liver metastatic tumors originating from colorectal cancers
    • DOI 10.1023/A:1026643009152
    • Nanashima A., Ito M., Sekine I., Naito S., Yamaguchi H., Nakagoe T., Ayabe H., Significance of angiogenic factors in liver metastatic tumors originating from colorectal cancers Digestive Diseases and Sciences 1998 43 12 2634 2640 (Pubitemid 29034916)
    • (1998) Digestive Diseases and Sciences , vol.43 , Issue.12 , pp. 2634-2640
    • Nanashima, A.1    Ito, M.2    Sekine, I.3    Naito, S.4    Yamaguchi, H.5    Nakagoe, T.6    Ayabe, H.7
  • 61
    • 0032483712 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in tumorigenesis (Part II)
    • Taketo M. M., Cyclooxygenase-2 inhibitors in tumorigenesis (part II) Journal of the National Cancer Institute 1998 90 21 1609 1620 (Pubitemid 28523435)
    • (1998) Journal of the National Cancer Institute , vol.90 , Issue.21 , pp. 1609-1620
    • Taketo, M.M.1
  • 63
    • 0027993458 scopus 로고
    • Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
    • Eberhart C. E., Coffey R. J., Radhika A., Giardiello F. M., Ferrenbach S., Dubois R. N., Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas Gastroenterology 1994 107 4 1183 1188 (Pubitemid 24294584)
    • (1994) Gastroenterology , vol.107 , Issue.4 , pp. 1183-1188
    • Eberhart, C.E.1    Coffey, R.J.2    Radhika, A.3    Giardiello, F.M.4    Ferrenbach, S.5    DuBois, R.N.6
  • 64
    • 0035496616 scopus 로고    scopus 로고
    • Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
    • Gupta R. A., DuBois R. N., Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2 Nature Reviews Cancer 2001 1 1 11 21 (Pubitemid 33741877)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.1 , pp. 11-21
    • Gupta, R.A.1    DuBois, R.N.2
  • 66
    • 0030606299 scopus 로고    scopus 로고
    • Suppression of intestinal polyposis in Apc(Δ716) knockout mice by inhibition of cyclooxygenase 2 (COX-2)
    • DOI 10.1016/S0092-8674(00)81988-1
    • Oshima M., Dinchuk J. E., Kargman S. L., Oshima H., Hancock B., Kwong E., Trzaskos J. M., Evans J. F., Taketo M. M., Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2) Cell 1996 87 5 803 809 (Pubitemid 26404280)
    • (1996) Cell , vol.87 , Issue.5 , pp. 803-809
    • Oshima, M.1    Dinchuk, J.E.2    Kargman, S.L.3    Oshima, H.4    Hancock, B.5    Kwong, E.6    Trzaskos, J.M.7    Evans, J.F.8    Taketo, M.M.9
  • 67
    • 0032901304 scopus 로고    scopus 로고
    • Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms
    • DOI 10.1002/(SICI)1098-2744(199903)24:3<177::AID-MC4>3.0.CO;2-6
    • Shattuck-Brandt R. L., Lamps L. W., Heppner Goss K. J., DuBois R. N., Matrisian L. M., Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms Molecular Carcinogenesis 1999 24 3 177 187 (Pubitemid 29169858)
    • (1999) Molecular Carcinogenesis , vol.24 , Issue.3 , pp. 177-187
    • Shattuck-Brandt, R.L.1    Lamps, L.W.2    Heppner Goss, K.J.3    DuBois, R.N.4    Matrisian, L.M.5
  • 70
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • DOI 10.1016/S0092-8674(00)81433-6
    • Tsujii M., Kawano S., Tsuji S., Sawaoka H., Hori M., DuBois R. N., Cyclooxygenase regulates angiogenesis induced by colon cancer cells Cell 1998 93 5 705 716 (Pubitemid 28257578)
    • (1998) Cell , vol.93 , Issue.5 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    DuBois, R.N.6
  • 73
    • 0033971808 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is related to prostaglandin biosynthesis and angiogenesis in human gastric cancer
    • Uefuji K., Ichikura T., Mochizuki H., Cyclooxygenase-2 expression is related to prostaglandin biosynthesis and angiogenesis in human gastric cancer Clinical Cancer Research 2000 6 1 135 138 (Pubitemid 30064985)
    • (2000) Clinical Cancer Research , vol.6 , Issue.1 , pp. 135-138
    • Uefuji, K.1    Ichikura, T.2    Mochizuki, H.3
  • 74
    • 0030468818 scopus 로고    scopus 로고
    • Cyclooxygenase, NSAIDs, and colorectal cancer
    • DOI 10.1007/BF02358623
    • DuBois R. N., Smalley W. E., Cyclooxygenase, NSAIDs, and colorectal cancer Journal of Gastroenterology 1996 31 6 898 906 (Pubitemid 27042276)
    • (1996) Journal of Gastroenterology , vol.31 , Issue.6 , pp. 898-906
    • DuBois, R.N.1    Smalley, W.E.2
  • 77
    • 0035865163 scopus 로고    scopus 로고
    • Angiogenesis in breast cancer: The role of transforming growth factor β and CD105
    • DOI 10.1002/1097-0029(20010215)52:4<437::AID-JEMT1029>3.0.CO;2-G
    • Li C., Guo B., Bernabeu C., Kumar S., Angiogenesis in breast cancer: the role of transforming growth factor and CD105 Microscopy Research and Technique 2001 52 4 437 449 (Pubitemid 32167832)
    • (2001) Microscopy Research and Technique , vol.52 , Issue.4 , pp. 437-449
    • Li, C.1    Guo, B.2    Bernabeu, C.3    Kumar, S.4
  • 78
    • 33646828741 scopus 로고    scopus 로고
    • The risk of developing metastatic disease in colorectal cancer is related to CD105-positive vessel count
    • DOI 10.1002/jso.20456
    • Romani A. A., Borghetti A. F., Del Rio P., Sianesi M., Soliani P., The risk of developing metastatic disease in colorectal cancer is related to CD105-positive vessel count Journal of Surgical Oncology 2006 93 6 446 455 (Pubitemid 44651267)
    • (2006) Journal of Surgical Oncology , vol.93 , Issue.6 , pp. 446-455
    • Romani, A.A.1    Borghetti, A.F.2    Del Rio, P.3    Sianesi, M.4    Soliani, P.5
  • 80
    • 64549113715 scopus 로고    scopus 로고
    • TGF- is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature
    • Walshe T. E., Saint-Geniez M., Maharaj A. S. R., Sekiyama E., Maldonado A. E., D'Amore P. A., TGF- is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature PLoS One 2009 4 4
    • (2009) PLoS One , vol.4 , Issue.4
    • Walshe, T.E.1    Saint-Geniez, M.2    Maharaj, A.S.R.3    Sekiyama, E.4    Maldonado, A.E.5    D'Amore, P.A.6
  • 82
    • 23744445106 scopus 로고    scopus 로고
    • Novel approaches in the therapy of metastatic renal cell carcinoma
    • DOI 10.1007/s00345-004-0466-0
    • Lam J. S., Leppert J. T., Belldegrun A. S., Figlin R. A., Novel approaches in the therapy of metastatic renal cell carcinoma World Journal of Urology 2005 23 3 202 212 (Pubitemid 41136043)
    • (2005) World Journal of Urology , vol.23 , Issue.3 , pp. 202-212
    • Lam, J.S.1    Leppert, J.T.2    Belldegrun, A.S.3    Figlin, R.A.4
  • 84
    • 0027933191 scopus 로고
    • Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis
    • Takahashi A., Sasaki H., Kim S. J., Tobisu K. I., Kakizoe T., Tsukamoto T., Kumamoto Y., Sugimura T., Terada M., Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis Cancer Research 1994 54 15 4233 4237 (Pubitemid 24258135)
    • (1994) Cancer Research , vol.54 , Issue.15 , pp. 4233-4237
    • Takahashi, A.1    Sasaki, H.2    Kim, S.J.3    Tobisu, K.-I.4    Kakizoe, T.5    Tsukamoto, T.6    Kumamoto, Y.7    Sugimura, T.8    Terada, M.9
  • 85
    • 28844484134 scopus 로고    scopus 로고
    • Renal-cell carcinoma
    • DOI 10.1056/NEJMra043172
    • Cohen H. T., McGovern F. J., Renal-cell carcinoma The New England Journal of Medicine 2005 353 23 2477 2490 (Pubitemid 41770167)
    • (2005) New England Journal of Medicine , vol.353 , Issue.23 , pp. 2477-2490
    • Cohen, H.T.1    McGovern, F.J.2
  • 86
    • 0029090338 scopus 로고
    • Tumour suppression by the human von Hippel-Lindau gene product
    • Iliopoulos O., Kibel A., Gray S., Kaelin W. G., Tumour suppression by the human von Hippel-Lindau gene product Nature Medicine 1995 1 8 822 826
    • (1995) Nature Medicine , vol.1 , Issue.8 , pp. 822-826
    • Iliopoulos, O.1    Kibel, A.2    Gray, S.3    Kaelin, W.G.4
  • 87
    • 0028805059 scopus 로고
    • Suppression of growth of renal carcinoma cells by the von Hippel-Lindau tumor suppressor gene
    • Chen F., Kishida T., Duh F. M., Renbaum P., Orcutt M. L., Schmidt L., Zbar B., Suppression of growth of renal carcinoma cells by the von Hippel-Lindau tumor suppressor gene Cancer Research 1995 55 21 4804 4807
    • (1995) Cancer Research , vol.55 , Issue.21 , pp. 4804-4807
    • Chen, F.1    Kishida, T.2    Duh, F.M.3    Renbaum, P.4    Orcutt, M.L.5    Schmidt, L.6    Zbar, B.7
  • 88
    • 1342280515 scopus 로고    scopus 로고
    • Inhibition of Hypoxia-Inducible Factor Is Sufficient for Growth Suppression of VHL-/- Tumors
    • Zimmer M., Doucette D., Siddiqui N., Iliopoulos O., Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL-/- tumors Molecular Cancer Research 2004 2 2 89 95 (Pubitemid 38250425)
    • (2004) Molecular Cancer Research , vol.2 , Issue.2 , pp. 89-95
    • Zimmer, M.1    Doucette, D.2    Siddiqui, N.3    Iliopoulos, O.4
  • 89
    • 77951877765 scopus 로고    scopus 로고
    • Alterations in VHL as potential biomarkers in renal-cell carcinoma
    • Gossage L., Eisen T., Alterations in VHL as potential biomarkers in renal-cell carcinoma Nature Reviews Clinical Oncology 2010 7 5 277 288
    • (2010) Nature Reviews Clinical Oncology , vol.7 , Issue.5 , pp. 277-288
    • Gossage, L.1    Eisen, T.2
  • 91
    • 38949161122 scopus 로고    scopus 로고
    • Collagen matrix assembly is driven by the interaction of von Hippel-Lindau tumor suppressor protein with hydroxylated collagen IV alpha 2
    • DOI 10.1038/sj.onc.1210709, PII 1210709
    • Kurban G., Duplan E., Ramlal N., Hudon V., Sado Y., Ninomiya Y., Pause A., Collagen matrix assembly is driven by the interaction of von Hippel-Lindau tumor suppressor protein with hydroxylated collagen IV alpha 2 Oncogene 2008 27 7 1004 1012 (Pubitemid 351225387)
    • (2008) Oncogene , vol.27 , Issue.7 , pp. 1004-1012
    • Kurban, G.1    Duplan, E.2    Ramlal, N.3    Hudon, V.4    Sado, Y.5    Ninomiya, Y.6    Pause, A.7
  • 92
    • 39049165830 scopus 로고    scopus 로고
    • Regulation of angiogenic factors by HDM2 in renal cell carcinoma
    • DOI 10.1158/0008-5472.CAN-06-4738
    • Carroll V. A., Ashcroft M., Regulation of angiogenic factors by HDM2 in renal cell carcinoma Cancer Research 2008 68 2 545 552 (Pubitemid 351380083)
    • (2008) Cancer Research , vol.68 , Issue.2 , pp. 545-552
    • Carroll, V.A.1    Ashcroft, M.2
  • 94
    • 34047131797 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and immunosuppression in cancer: Current knowledge and potential for new therapy
    • DOI 10.1517/14712598.7.4.449
    • Johnson B. F., Clay T. M., Hobeika A. C., Lyerly H. K., Morse M. A., Vascular endothelial growth factor and immunosuppression in cancer: current knowledge and potential for new therapy Expert Opinion on Biological Therapy 2007 7 4 449 460 (Pubitemid 46524672)
    • (2007) Expert Opinion on Biological Therapy , vol.7 , Issue.4 , pp. 449-460
    • Johnson, B.F.1    Clay, T.M.2    Hobeika, A.C.3    Lyerly, H.K.4    Morse, M.A.5
  • 95
    • 70350010317 scopus 로고    scopus 로고
    • Immunotherapeutic strategies in kidney cancerwhen TKIs are not enough
    • Biswas S., Eisen T., Immunotherapeutic strategies in kidney cancerwhen TKIs are not enough Nature Reviews Clinical Oncology 2009 6 8 478 487
    • (2009) Nature Reviews Clinical Oncology , vol.6 , Issue.8 , pp. 478-487
    • Biswas, S.1    Eisen, T.2
  • 96
    • 46049104223 scopus 로고    scopus 로고
    • American Cancer Society, Cancer Facts Figures 2010 2010. http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/ document/acspc-026238.pdf
    • (2010) Cancer Facts Figures 2010
    • Cancer Society, A.1
  • 97
    • 0028092991 scopus 로고
    • Gene therapy through signal transduction pathways and angiogenic growth factors as therapeutic targets in breast cancer
    • Harris A. L., Fox S., Bicknell R., Leek R., Relf M., LeJeune S., Kaklamanis L., Gene therapy through signal transduction pathways and angiogenic growth factors as therapeutic targets in breast cancer Cancer 1994 74 3 1021 1025 (Pubitemid 24231997)
    • (1994) Cancer , vol.74 , Issue.3 , pp. 1021-1025
    • Harris, A.L.1    Fox, S.2    Bicknell, R.3    Leek, R.4    Relf, M.5    LeJeune, S.6    Kaklamanis, L.7
  • 98
    • 0034650744 scopus 로고    scopus 로고
    • Oncogenes and tumor angiogenesis: Differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts
    • Rak J., Mitsuhashi Y., Sheehan C., Tamir A., Viloria-Petit A., Filmus J., Mansour S. J., Ahn N. G., Kerbel R. S., Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts Cancer Research 2000 60 2 490 498 (Pubitemid 30070780)
    • (2000) Cancer Research , vol.60 , Issue.2 , pp. 490-498
    • Rak, J.1    Mitsuhashi, Y.2    Sheehan, C.3    Tamir, A.4    Viloria-Petit, A.5    Filmus, J.6    Mansour, S.J.7    Ahn, N.G.8    Kerbel, R.S.9
  • 100
    • 33751074452 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 in human breast and prostate cancer
    • DOI 10.1677/erc.1.00728
    • Kimbro K. S., Simons J. W., Hypoxia-inducible factor-1 in human breast and prostate cancer Endocrine-Related Cancer 2006 13 3 739 749 (Pubitemid 44763255)
    • (2006) Endocrine-Related Cancer , vol.13 , Issue.3 , pp. 739-749
    • Kimbro, K.S.1    Simons, J.W.2
  • 101
    • 0035362633 scopus 로고    scopus 로고
    • Overexpression of matrix-metalloproteinase-9 in human breast cancer: A potential favourable indicator in node-negative patients
    • DOI 10.1054/bjoc.2001.1810
    • Scorilas A., Karameris A., Arnogiannaki N., Ardavanis A., Bassilopoulos P., Trangas T., Talieri M., Overexpression of matrix-metalloproteinase-9 in human breast cancer: a potential favourable indicator in node-negative patients British Journal of Cancer 2001 84 11 1488 1496 (Pubitemid 32579341)
    • (2001) British Journal of Cancer , vol.84 , Issue.11 , pp. 1488-1496
    • Scorilas, A.1    Karameris, A.2    Arnogiannaki, N.3    Ardavanis, A.4    Bassilopoulos, P.5    Trangas, T.6    Talieri, M.7
  • 103
    • 0032830536 scopus 로고    scopus 로고
    • Vascular endothelial growth factor A (VEGF-A) mRNA expression levels decrease after menopause breast tissue but not in breast cancer lesions
    • DOI 10.1038/sj.bjc.6690681
    • Greb R. R., Maier I., Wallwiener D., Kiesel L., Vascular endothelial growth factor A (VEGF-A) mRNA expression levels decrease after menopause in normal breast tissue but not in breast cancer lesions British Journal of Cancer 1999 81 2 225 231 (Pubitemid 29423699)
    • (1999) British Journal of Cancer , vol.81 , Issue.2 , pp. 225-231
    • Greb, R.R.1    Maier, I.2    Wallwiener, D.3    Kiesel, L.4
  • 105
    • 0036731988 scopus 로고    scopus 로고
    • Transcriptional regulation of vascular endothelial growth factor by estradiol and tamoxifen in breast cancer cells: A complex interplay between estrogen receptors α and β
    • Buteau-Lozano H., Ancelin M., Lardeux B., Milanini J., Perrot-Applanat M., Transcriptional regulation of vascular endothelial growth factor by estradiol and tamoxifen in breast cancer cells: a complex interplay between estrogen receptors and Cancer Research 2002 62 17 4977 4984 (Pubitemid 34984422)
    • (2002) Cancer Research , vol.62 , Issue.17 , pp. 4977-4984
    • Buteau-Lozano, H.1    Ancelin, M.2    Lardeux, B.3    Milanini, J.4    Perrot-Applanat, M.5
  • 106
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon D. J., Clark G. M., Wong S. G., Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene Science 1987 235 4785 177 182 (Pubitemid 17231334)
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 108
    • 33750584030 scopus 로고    scopus 로고
    • HER2 signaling modulates the equilibrium between pro- and antiangiogenic factors via distinct pathways: Implications for HER2-targeted antibody therapy
    • DOI 10.1038/sj.onc.1209685, PII 1209685
    • Wen X. F., Yang G., Mao W., Thornton A., Liu J., Bast R. C., Le X. F., HER2 signaling modulates the equilibrium between pro- and antiangiogenic factors via distinct pathways: implications for HER2-targeted antibody therapy Oncogene 2006 25 52 6986 6996 (Pubitemid 44684839)
    • (2006) Oncogene , vol.25 , Issue.52 , pp. 6986-6996
    • Wen, X.-F.1    Yang, G.2    Mao, W.3    Thornton, A.4    Liu, J.5    Bast Jr., R.C.6    Le, X.-F.7
  • 109
    • 33644529055 scopus 로고    scopus 로고
    • ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells
    • Klos K. S., Wyszomierski S. L., Sun M., Tan M., Zhou X., Li P., Yang W., Yin G., Hittelman W. N., Yu D., ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells Cancer Research 2006 66 4 2028 2037
    • (2006) Cancer Research , vol.66 , Issue.4 , pp. 2028-2037
    • Klos, K.S.1    Wyszomierski, S.L.2    Sun, M.3    Tan, M.4    Zhou, X.5    Li, P.6    Yang, W.7    Yin, G.8    Hittelman, W.N.9    Yu, D.10
  • 110
    • 70350068312 scopus 로고    scopus 로고
    • Breast cancer cells stimulate osteoprotegerin (OPG) production by endothelial cells through direct cell contact
    • Reid P. E., Brown N. J., Holen I., Breast cancer cells stimulate osteoprotegerin (OPG) production by endothelial cells through direct cell contact Molecular Cancer 2009 8 49
    • (2009) Molecular Cancer , vol.8 , pp. 49
    • Reid, P.E.1    Brown, N.J.2    Holen, I.3
  • 113
    • 0036273766 scopus 로고    scopus 로고
    • Closing in on the biological functions of Fps/Fes and Fer
    • DOI 10.1038/nrm783
    • Greer P., Closing in on the biological functions of Fps/Fes and Fer Nature Reviews Molecular Cell Biology 2002 3 4 278 289 (Pubitemid 34619263)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.4 , pp. 278-289
    • Greer, P.1
  • 114
    • 79951830119 scopus 로고    scopus 로고
    • Fes tyrosine kinase expression in the tumor niche correlates with enhanced tumor growth, angiogenesis, circulating tumor cells, metastasis, and infiltrating macrophages
    • Zhang S., Chitu V., Stanley E. R., Elliott B. E., Greer P. A., Fes tyrosine kinase expression in the tumor niche correlates with enhanced tumor growth, angiogenesis, circulating tumor cells, metastasis, and infiltrating macrophages Cancer Research 2011 71 4 1465 1473
    • (2011) Cancer Research , vol.71 , Issue.4 , pp. 1465-1473
    • Zhang, S.1    Chitu, V.2    Stanley, E.R.3    Elliott, B.E.4    Greer, P.A.5
  • 115
    • 0346059598 scopus 로고    scopus 로고
    • Tamoxifen Inhibits Secretion of Vascular Endothelial Growth Factor in Breast Cancer in Vivo
    • Garvin S., Dabrosin C., Tamoxifen inhibits secretion of vascular endothelial growth factor in breast cancer in vivo Cancer Research 2003 63 24 8742 8748 (Pubitemid 38064052)
    • (2003) Cancer Research , vol.63 , Issue.24 , pp. 8742-8748
    • Garvin, S.1    Dabrosin, C.2
  • 116
    • 56949092327 scopus 로고    scopus 로고
    • Tamoxifen decreases extracellular TGF- 1 secreted from breast cancer cellsa post-translational regulation involving matrix metalloproteinase activity
    • Nilsson U. W., Jnsson J. A., Dabrosin C., Tamoxifen decreases extracellular TGF- 1 secreted from breast cancer cellsa post-translational regulation involving matrix metalloproteinase activity Experimental Cell Research 2009 315 1 1 9
    • (2009) Experimental Cell Research , vol.315 , Issue.1 , pp. 1-9
    • Nilsson, U.W.1    Jnsson, J.A.2    Dabrosin, C.3
  • 117
    • 78651398665 scopus 로고    scopus 로고
    • Tamoxifen, flaxseed, and the lignan enterolactone increase stroma- and cancer cell-derived IL-1Ra and decrease tumor angiogenesis in estrogen-dependent breast cancer
    • Lindahl G., Saarinen N., Abrahamsson A., Dabrosin C., Tamoxifen, flaxseed, and the lignan enterolactone increase stroma- and cancer cell-derived IL-1Ra and decrease tumor angiogenesis in estrogen-dependent breast cancer Cancer Research 2011 71 1 51 60
    • (2011) Cancer Research , vol.71 , Issue.1 , pp. 51-60
    • Lindahl, G.1    Saarinen, N.2    Abrahamsson, A.3    Dabrosin, C.4
  • 118
    • 1642374858 scopus 로고    scopus 로고
    • Multiple myeloma
    • DOI 10.1016/S0140-6736(04)15736-X, PII S014067360415736X
    • Sirohi B., Powles R., Multiple myeloma The Lancet 2004 363 9412 875 887 (Pubitemid 38368839)
    • (2004) Lancet , vol.363 , Issue.9412 , pp. 875-887
    • Sirohi, B.1    Powles, R.2
  • 120
    • 49749102426 scopus 로고    scopus 로고
    • The role of microenvironment in tumor angiogenesis
    • Ribatti D., Vacca A., The role of microenvironment in tumor angiogenesis Genes and Nutrition 2008 3 1 29 34
    • (2008) Genes and Nutrition , vol.3 , Issue.1 , pp. 29-34
    • Ribatti, D.1    Vacca, A.2
  • 121
    • 31444447073 scopus 로고    scopus 로고
    • Bone marrow angiogenesis in multiple myeloma
    • DOI 10.1038/sj.leu.2404067, PII 2404067
    • Vacca A., Ribatti D., Bone marrow angiogenesis in multiple myeloma Leukemia 2006 20 2 193 199 (Pubitemid 43148652)
    • (2006) Leukemia , vol.20 , Issue.2 , pp. 193-199
    • Vacca, A.1    Ribatti, D.2
  • 122
    • 33746257305 scopus 로고    scopus 로고
    • Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma
    • DOI 10.1038/sj.onc.1209456, PII 1209456
    • Ribatti D., Nico B., Vacca A., Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma Oncogene 2006 25 31 4257 4266 (Pubitemid 44100496)
    • (2006) Oncogene , vol.25 , Issue.31 , pp. 4257-4266
    • Ribatti, D.1    Nico, B.2    Vacca, A.3
  • 123
    • 13544255403 scopus 로고    scopus 로고
    • The pathophysiologic role of VEGF in hematologic malignancies: Therapeutic implications
    • DOI 10.1182/blood-2004-07-2909
    • Podar K., Anderson K. C., The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications Blood 2005 105 4 1383 1395 (Pubitemid 40223651)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1383-1395
    • Podar, K.1    Anderson, K.C.2
  • 124
    • 34547106018 scopus 로고    scopus 로고
    • Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
    • DOI 10.1038/nrc2189, PII NRC2189
    • Hideshima T., Mitsiades C., Tonon G., Richardson P. G., Anderson K. C., Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets Nature Reviews Cancer 2007 7 8 585 598 (Pubitemid 47106630)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.8 , pp. 585-598
    • Hideshima, T.1    Mitsiades, C.2    Tonon, G.3    Richardson, P.G.4    Anderson, K.C.5
  • 125
    • 18144407693 scopus 로고    scopus 로고
    • Targeting signalling pathways for the treatment of multiple myeloma
    • DOI 10.1517/14728222.9.2.359
    • Podar K., Hideshima T., Chauhan D., Anderson K. C., Targeting signalling pathways for the treatment of multiple myeloma Expert Opinion on Therapeutic Targets 2005 9 2 359 381 (Pubitemid 40613874)
    • (2005) Expert Opinion on Therapeutic Targets , vol.9 , Issue.2 , pp. 359-381
    • Podar, K.1    Hideshima, T.2    Chauhan, D.3    Anderson, K.C.4
  • 127
    • 33947310737 scopus 로고    scopus 로고
    • Inhibition of VEGF signaling pathways in multiple myeloma and other malignancies
    • Podar K., Anderson K. C., Inhibition of VEGF signaling pathways in multiple myeloma and other malignancies Cell Cycle 2007 6 5 538 542 (Pubitemid 46440425)
    • (2007) Cell Cycle , vol.6 , Issue.5 , pp. 538-542
    • Podar, K.1    Anderson, K.C.2
  • 130
    • 25144505830 scopus 로고    scopus 로고
    • A role for niches in hematopoietic cell development
    • DOI 10.1080/10245330500067249
    • Heissig B., Ohki Y., Sato Y., Rafii S., Werb Z., Hattori K., A role for niches in hematopoietic cell development Hematology 2005 10 3 247 253 (Pubitemid 41801141)
    • (2005) Hematology , vol.10 , Issue.3 , pp. 247-253
    • Heissig, B.1    Ohki, Y.2    Sato, Y.3    Rafii, S.4    Werb, Z.5    Hattori, K.6
  • 131
    • 26844520899 scopus 로고    scopus 로고
    • The bone marrow vascular niche: Home of HSC differentiation and mobilization
    • Kopp H. G., Avecilla S. T., Hooper A. T., Rafii S., The bone marrow vascular niche: home of HSC differentiation and mobilization Physiology 2005 20 5 349 356 (Pubitemid 41457400)
    • (2005) Physiology , Issue.5 , pp. 349-356
    • Kopp, H.-G.1    Avecilla, S.T.2    Hooper, A.T.3    Rafii, S.4
  • 132
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: An organizing principle for drug discovery?
    • DOI 10.1038/nrd2115, PII NRD2115
    • Folkman J., Angiogenesis: an organizing principle for drug discovery? Nature Reviews Drug Discovery 2007 6 4 273 286 (Pubitemid 46505878)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.4 , pp. 273-286
    • Folkman, J.1
  • 135
    • 1942534043 scopus 로고    scopus 로고
    • The evolution of thalidomide and its IMiD derivatives as anticancer agents
    • Bartlett J. B., Dredge K., Dalgleish A. G., The evolution of thalidomide and its IMiD derivatives as anticancer agents Nature Reviews Cancer 2004 4 4 314 322 (Pubitemid 38525287)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.4 , pp. 314-322
    • Bartlett, J.B.1    Dredge, K.2    Dalgleish, A.G.3
  • 137
    • 0035211277 scopus 로고    scopus 로고
    • Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma
    • D'Amato R. J., Lentzsch S., Anderson K. C., Rogers M. S., Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma Seminars in Oncology 2001 28 6 597 601 (Pubitemid 33134418)
    • (2001) Seminars in Oncology , vol.28 , Issue.6 , pp. 597-601
    • D'Amato, R.J.1    Lentzsch, S.2    Anderson, K.C.3    Rogers, M.S.4
  • 139
    • 80053542260 scopus 로고    scopus 로고
    • Genentech, Avastin (bevacizumab) product insert 2011. http://www.gene.com/gene/products/information/pdf/avastin-prescribing.pdf
    • (2011) Avastin (bevacizumab) product insert
  • 140
    • 1642525642 scopus 로고    scopus 로고
    • The role of new agents in the treatment of colorectal cancer
    • DOI 10.1159/000076329
    • Folprecht G., Khne C. H., The role of new agents in the treatment of colorectal cancer Oncology 2004 66 1 1 17 (Pubitemid 38410674)
    • (2004) Oncology , vol.66 , Issue.1 , pp. 1-17
    • Folprecht, G.1    Kohne, C.-H.2
  • 141
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta L. G., Chen H., O'Connor S. J., Chisholm V., Meng Y. G., Krummen L., Winkler M., Ferrara N., Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders Cancer Research 1997 57 20 4593 4599 (Pubitemid 27441066)
    • (1997) Cancer Research , vol.57 , Issue.20 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3    Chisholm, V.4    Meng, Y.G.5    Krummen, L.6    Winkler, M.7    Ferrara, N.8
  • 142
    • 0347719608 scopus 로고    scopus 로고
    • Technology evaluation: Bevacizumab, Genentech/Roche
    • Salgaller M. L., Technology evaluation: bevacizumab, Genentech/Roche Current Opinion in Molecular Therapeutics 2003 5 6 657 667 (Pubitemid 38094437)
    • (2003) Current Opinion in Molecular Therapeutics , vol.5 , Issue.6 , pp. 657-667
    • Salgaller, M.L.1
  • 143
    • 79954434849 scopus 로고    scopus 로고
    • AVANT: Results from a randomized, three-arm multinational phase III study to investigate bevacizumab with either XELOX or FOLFOX4 versus FOLFOX4 alone as adjuvant treatment for colon cancer
    • De Gramont V. C. E., Tabernero J., AVANT: results from a randomized, three-arm multinational phase III study to investigate bevacizumab with either XELOX or FOLFOX4 versus FOLFOX4 alone as adjuvant treatment for colon cancer 29, abstract no 362 Proceedings of the Gastrointestinal Cancer Symposium (ASCO) 2011
    • (2011) Proceedings of the Gastrointestinal Cancer Symposium (ASCO) , vol.293
    • De Gramont, V.C.E.1    Tabernero, J.2
  • 146
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • Ferrara N., Hillan K. J., Gerber H. P., Novotny W., Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer Nature Reviews Drug Discovery 2004 3 5 391 400 (Pubitemid 38618122)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.5 , pp. 391-400
    • Ferrara, N.1    Hillan, K.J.2    Gerber, H.-P.3    Novotny, W.4
  • 151
    • 73349120007 scopus 로고    scopus 로고
    • Independent review of E2100: A phase III trial of bevacizumab plus paclitaxel versus paclitaxel in women with metastatic breast cancer
    • Gray R., Bhattacharya S., Bowden C., Miller K., Comis R. L., Independent review of E2100: a phase III trial of bevacizumab plus paclitaxel versus paclitaxel in women with metastatic breast cancer Journal of Clinical Oncology 2009 27 30 4966 4972
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.30 , pp. 4966-4972
    • Gray, R.1    Bhattacharya, S.2    Bowden, C.3    Miller, K.4    Comis, R.L.5
  • 152
    • 78649586869 scopus 로고    scopus 로고
    • Bevacizumab and breast cancer: The E2100 outlier
    • Fojo T., Wilkerson J., Bevacizumab and breast cancer: the E2100 outlier The Lancet Oncology 2010 11 12 1117 1119
    • (2010) The Lancet Oncology , vol.11 , Issue.12 , pp. 1117-1119
    • Fojo, T.1    Wilkerson, J.2
  • 153
    • 80053502916 scopus 로고    scopus 로고
    • Independet review of E2100 progression-free survival (PFS) with the addition of bevacizumab (B) to paclitaxel (P) as initial chemotherpary for metastatic brease cancer (MBC)
    • Klencke B., Bhattacharya S., Samant M. K., Independet review of E2100 progression-free survival (PFS) with the addition of bevacizumab (B) to paclitaxel (P) as initial chemotherpary for metastatic brease cancer (MBC) 26, abstract 1036 Proceedings of the 2008 ASCO Annual Meeting. Poster Discussion Session, Breast CancerMetastatic, 2008
    • (2008) Proceedings of the 2008 ASCO Annual Meeting Poster Discussion Session, Breast CancerMetastatic , vol.261
    • Klencke, B.1    Bhattacharya, S.2    Samant, M.K.3
  • 155
    • 79953874259 scopus 로고    scopus 로고
    • RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer
    • Robert N. J., Diéras V., Glaspy J., RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer Journal of Clinical Oncology 2011 29 10 1252 1260
    • (2011) Journal of Clinical Oncology , vol.29 , Issue.10 , pp. 1252-1260
    • Robert, N.J.1    Diéras, V.2    Glaspy, J.3
  • 156
    • 79953848263 scopus 로고    scopus 로고
    • Bevacizumab for advanced breast cancer: All tied up with a RIBBON?
    • Burstein H. J., Bevacizumab for advanced breast cancer: all tied up with a RIBBON? Journal of Clinical Oncology 2011 29 10 1232 1235
    • (2011) Journal of Clinical Oncology , vol.29 , Issue.10 , pp. 1232-1235
    • Burstein, H.J.1
  • 157
    • 79551559952 scopus 로고    scopus 로고
    • Bevacizumab treatment for solid tumors: Boon or bust?
    • Hayes D. F., Bevacizumab treatment for solid tumors: boon or bust? Journal of the American Medical Association 2011 305 5 506 508
    • (2011) Journal of the American Medical Association , vol.305 , Issue.5 , pp. 506-508
    • Hayes, D.F.1
  • 158
    • 79551520348 scopus 로고    scopus 로고
    • Treatment-related mortality with bevacizumab in cancer patients: A meta-analysis
    • Ranpura V., Hapan S., Wu S., Treatment-related mortality with bevacizumab in cancer patients: a meta-analysis Journal of the American Medical Association 2011 305 5 487 494
    • (2011) Journal of the American Medical Association , vol.305 , Issue.5 , pp. 487-494
    • Ranpura, V.1    Hapan, S.2    Wu, S.3
  • 159
    • 0037010086 scopus 로고    scopus 로고
    • IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer
    • Herbst R. S., Hong W. K., IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer Seminars in Oncology 2002 29 5, supplement 14 18 30 (Pubitemid 35191043)
    • (2002) Seminars in Oncology , vol.29 , Issue.5 SUPPL. 14 , pp. 18-30
    • Herbst, R.S.1    Hong, W.K.2
  • 160
    • 0035409904 scopus 로고    scopus 로고
    • IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer
    • Herbst R. S., Kim E. S., Harari P. M., IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer Expert Opinion on Biological Therapy 2001 1 4 719 732 (Pubitemid 33769082)
    • (2001) Expert Opinion on Biological Therapy , vol.1 , Issue.4 , pp. 719-732
    • Herbst, R.S.1    Kim, E.S.2    Harari, P.M.3
  • 161
    • 0034754136 scopus 로고    scopus 로고
    • Epidermal growth factor receptor biology (IMC-C225)
    • DOI 10.1097/00001622-200111000-00014
    • Kim E. S., Khuri F. R., Herbst R. S., Epidermal growth factor receptor biology (IMC-C225) Current Opinion in Oncology 2001 13 6 506 513 (Pubitemid 33027904)
    • (2001) Current Opinion in Oncology , vol.13 , Issue.6 , pp. 506-513
    • Kim, E.S.1    Khuri, F.R.2    Herbst, R.S.3
  • 163
    • 33750818148 scopus 로고    scopus 로고
    • Panitumumab in colon cancer: A review and summary of ongoing trials
    • DOI 10.1517/14712598.6.11.1229
    • Wainberg Z., Hecht J. R., Panitumumab in colon cancer: a review and summary of ongoing trials Expert Opinion on Biological Therapy 2006 6 11 1229 1235 (Pubitemid 44714148)
    • (2006) Expert Opinion on Biological Therapy , vol.6 , Issue.11 , pp. 1229-1235
    • Wainberg, Z.1    Hecht, J.R.2
  • 164
    • 33749032101 scopus 로고    scopus 로고
    • Role of panitumumab in the management of metastatic colorectal cancer of metastatic colorectal cancer
    • Saif M. W., Cohenuram M., Role of panitumumab in the management of metastatic colorectal cancer of metastatic colorectal cancer Clinical Colorectal Cancer 2006 6 2 118 124 (Pubitemid 44445746)
    • (2006) Clinical Colorectal Cancer , vol.6 , Issue.2 , pp. 118-124
    • Saif, M.W.1    Cohenuram, M.2
  • 165
    • 33745909120 scopus 로고    scopus 로고
    • Randomized phase III trial results of Panitumumab, a fully human anti-epidermal growth factor receptor monoclonal antibody, in metastatic colorectal cancer
    • Gibson T. B., Ranganathan A., Grothey A., Randomized phase III trial results of Panitumumab, a fully human anti-epidermal growth factor receptor monoclonal antibody, in metastatic colorectal cancer Clinical Colorectal Cancer 2006 6 1 29 31 (Pubitemid 44043998)
    • (2006) Clinical Colorectal Cancer , vol.6 , Issue.1 , pp. 29-31
    • Gibson, T.B.1    Ranganathan, A.2    Grothey, A.3
  • 166
    • 21844438498 scopus 로고    scopus 로고
    • Recent results and ongoing trials with panitumumab (ABX-EGF), a fully human anti-epidermal growth factor receptor antibody, in metastatic colorectal cancer
    • Tyagi P., Chu E., Jain V. K., Recent results and ongoing trials with panitumumab (ABX-EGF), a fully human anti-epidermal growth factor receptor antibody, in metastatic colorectal cancer Clinical Colorectal Cancer 2005 5 1 21 23
    • (2005) Clinical Colorectal Cancer , vol.5 , Issue.1 , pp. 21-23
    • Tyagi, P.1    Chu, E.2    Jain, V.K.3
  • 168
    • 65349186800 scopus 로고    scopus 로고
    • Aflibercept (AVE0005): An alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors
    • Chu Q. S. C., Aflibercept (AVE0005): an alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors Expert Opinion on Biological Therapy 2009 9 2 263 271
    • (2009) Expert Opinion on Biological Therapy , vol.9 , Issue.2 , pp. 263-271
    • Chu, Q.S.C.1
  • 173
    • 67650674112 scopus 로고    scopus 로고
    • Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer
    • Krupitskaya Y., Wakelee H. A., Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer Current Opinion in Investigational Drugs 2009 10 6 597 605
    • (2009) Current Opinion in Investigational Drugs , vol.10 , Issue.6 , pp. 597-605
    • Krupitskaya, Y.1    Wakelee, H.A.2
  • 174
    • 73349135923 scopus 로고    scopus 로고
    • TRIO-012: A multicenter, multinational, randomized, double-blind phase III study of IMC-1121B plus docetaxel versus placebo plus docetaxel in previously untreated patients with HER2-negative, unresectable, locally recurrent or metastatic breast cancer
    • MacKey J., Gelmon K., Martin M., McCarthy N., Pinter T., Rupin M., Youssoufian H., TRIO-012: a multicenter, multinational, randomized, double-blind phase III study of IMC-1121B plus docetaxel versus placebo plus docetaxel in previously untreated patients with HER2-negative, unresectable, locally recurrent or metastatic breast cancer Clinical Breast Cancer 2009 9 4 258 261
    • (2009) Clinical Breast Cancer , vol.9 , Issue.4 , pp. 258-261
    • MacKey, J.1    Gelmon, K.2    Martin, M.3    McCarthy, N.4    Pinter, T.5    Rupin, M.6    Youssoufian, H.7
  • 175
    • 34347395733 scopus 로고    scopus 로고
    • Trastuzumab - Mechanism of action and use in clinical practice
    • DOI 10.1056/NEJMra043186
    • Hudis C. A., Trastuzumabmechanism of action and use in clinical practice The New England Journal of Medicine 2007 357 1 39 51 (Pubitemid 47026733)
    • (2007) New England Journal of Medicine , vol.357 , Issue.1 , pp. 39-51
    • Hudis, C.A.1
  • 176
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • DOI 10.1016/j.ccr.2005.09.005, PII S1535610805002989
    • Casanovas O., Hicklin D. J., Bergers G., Hanahan D., Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors Cancer Cell 2005 8 4 299 309 (Pubitemid 41443415)
    • (2005) Cancer Cell , vol.8 , Issue.4 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4
  • 177
    • 70349782389 scopus 로고    scopus 로고
    • An overview of small-molecule inhibitors of VEGFR signaling
    • Ivy S. P., Wick J. Y., Kaufman B. M., An overview of small-molecule inhibitors of VEGFR signaling Nature Reviews Clinical Oncology 2009 6 10 569 579
    • (2009) Nature Reviews Clinical Oncology , vol.6 , Issue.10 , pp. 569-579
    • Ivy, S.P.1    Wick, J.Y.2    Kaufman, B.M.3
  • 178
    • 33747855481 scopus 로고    scopus 로고
    • Comparing antibody and small-molecule therapies for cancer
    • DOI 10.1038/nrc1913, PII NRC1913
    • Imai K., Takaoka A., Comparing antibody and small-molecule therapies for cancer Nature Reviews Cancer 2006 6 9 714 727 (Pubitemid 44286003)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.9 , pp. 714-727
    • Imai, K.1    Takaoka, A.2
  • 179
    • 0036401042 scopus 로고    scopus 로고
    • Design and discovery of small molecules targeting Raf-1 kinase
    • DOI 10.2174/1381612023393125
    • Lowinger T. B., Riedl B., Dumas J., Smith R. A., Design and discovery of small molecules targeting raf-1 kinase Current Pharmaceutical Design 2002 8 25 2269 2278 (Pubitemid 35189900)
    • (2002) Current Pharmaceutical Design , vol.8 , Issue.25 , pp. 2269-2278
    • Lowinger, T.B.1    Riedl, B.2    Dumas, J.3    Smith, R.A.4
  • 181
    • 34548316976 scopus 로고    scopus 로고
    • Molecular basis for sunitinib efficacy and future clinical development
    • DOI 10.1038/nrd2380, PII NRD2380
    • Faivre S., Demetri G., Sargent W., Raymond E., Molecular basis for sunitinib efficacy and future clinical development Nature Reviews Drug Discovery 2007 6 9 734 745 (Pubitemid 47338181)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.9 , pp. 734-745
    • Faivre, S.1    Demetri, G.2    Sargent, W.3    Raymond, E.4
  • 183
    • 0041672482 scopus 로고    scopus 로고
    • SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
    • Schueneman A. J., Himmelfarb E., Geng L., Tan J., Donnelly E., Mendel D., McMahon G., Hallahan D. E., SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models Cancer Research 2003 63 14 4009 4016 (Pubitemid 36917920)
    • (2003) Cancer Research , vol.63 , Issue.14 , pp. 4009-4016
    • Schueneman, A.J.1    Himmelfarb, E.2    Geng, L.3    Tan, J.4    Donnelly, E.5    Mendel, D.6    McMahon, G.7    Hallahan, D.E.8
  • 188
    • 34250619165 scopus 로고    scopus 로고
    • The mammalian target of rapamycin signaling pathway: Twists and turns in the road to cancer therapy
    • DOI 10.1158/1078-0432.CCR-06-2798
    • Abraham R. T., Gibbons J. J., The mammalian target of rapamycin signaling pathway: twists and turns in the road to cancer therapy Clinical Cancer Research 2007 13 11 3109 3114 (Pubitemid 46944891)
    • (2007) Clinical Cancer Research , vol.13 , Issue.11 , pp. 3109-3114
    • Abraham, R.T.1    Gibbons, J.J.2
  • 189
    • 33747819801 scopus 로고    scopus 로고
    • mTOR and cancer: Insights into a complex relationship
    • DOI 10.1038/nrc1974, PII NRC1974
    • Sabatini D. M., mTOR and cancer: insights into a complex relationship Nature Reviews Cancer 2006 6 9 729 734 (Pubitemid 44286004)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.9 , pp. 729-734
    • Sabatini, D.M.1
  • 192
    • 77950541904 scopus 로고    scopus 로고
    • Everolimus (RAD001) in the treatment of advanced renal cell carcinoma: A review
    • Agarwala S. S., Case S., Everolimus (RAD001) in the treatment of advanced renal cell carcinoma: a review Oncologist 2010 15 3 236 245
    • (2010) Oncologist , vol.15 , Issue.3 , pp. 236-245
    • Agarwala, S.S.1    Case, S.2
  • 200
    • 34447286369 scopus 로고    scopus 로고
    • Does lapatinib, a small-molecule tyrosine kinase inhibitor, constitute a breakthrough in the treatment of breast cancer?
    • Ito Y., Tokudome N., Sugihara T., Takahashi S., Hatake K., Does lapatinib, a small-molecule tyrosine kinase inhibitor, constitute a breakthrough in the treatment of breast cancer? Breast Cancer 2007 14 2 156 162
    • (2007) Breast Cancer , vol.14 , Issue.2 , pp. 156-162
    • Ito, Y.1    Tokudome, N.2    Sugihara, T.3    Takahashi, S.4    Hatake, K.5
  • 201
    • 33751205030 scopus 로고    scopus 로고
    • Lapatinib: Current status and future directions in breast cancer
    • DOI 10.1634/theoncologist.11-10-1047
    • Moy B., Goss P. E., Lapatinib: current status and future directions in breast cancer Oncologist 2006 11 10 1047 1057 (Pubitemid 44788395)
    • (2006) Oncologist , vol.11 , Issue.10 , pp. 1047-1057
    • Moy, B.1    Goss, P.E.2
  • 202
    • 2942592008 scopus 로고    scopus 로고
    • Dual kinase inhibition in the treatment of breast cancer: Initial experience with the EGFR/ErbB-2 inhibitor lapatinib
    • Burris H. A., Dual kinase inhibition in the treatment of breast cancer: initial experience with the EGFR/ErbB-2 inhibitor lapatinib Oncologist 2004 supplement 3 3 10 15
    • (2004) Oncologist , Issue.3 SUPPL. 3 , pp. 10-15
    • Burris, H.A.1
  • 203
    • 33846709211 scopus 로고    scopus 로고
    • Lapatinib: A dual inhibitor of EGFR and HER2 tyrosine kinase activity
    • DOI 10.1517/14712598.7.2.257
    • Montemurro F., Valabrega G., Aglietta M., Lapatinib: a dual inhibitor of EGFR and HER2 tyrosine kinase activity Expert Opinion on Biological Therapy 2007 7 2 257 268 (Pubitemid 46192173)
    • (2007) Expert Opinion on Biological Therapy , vol.7 , Issue.2 , pp. 257-268
    • Montemurro, F.1    Valabrega, G.2    Aglietta, M.3
  • 206
    • 11244257032 scopus 로고    scopus 로고
    • The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer
    • Chu I., Blackwell K., Chen S., Slingerland J., The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer Cancer Research 2005 65 1 18 25 (Pubitemid 40070791)
    • (2005) Cancer Research , vol.65 , Issue.1 , pp. 18-25
    • Chu, I.1    Blackwell, K.2    Chen, S.3    Slingerland, J.4
  • 207
    • 33744466541 scopus 로고    scopus 로고
    • Antiangiogenic therapy: A universal chemosensitization strategy for cancer?
    • DOI 10.1126/science.1125950
    • Kerbel R. S., Antiangiogenic therapy: a universal chemosensitization strategy for cancer? Science 2006 312 5777 1171 1175 (Pubitemid 43801134)
    • (2006) Science , vol.312 , Issue.5777 , pp. 1171-1175
    • Kerbel, R.S.1
  • 208
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • Kerbel R. S., Kamen B. A., The anti-angiogenic basis of metronomic chemotherapy Nature Reviews Cancer 2004 4 6 423 436 (Pubitemid 38745528)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.6 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2


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