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Volumn 6, Issue 2, 2006, Pages 118-124

Role of panitumumab in the management of metastatic colorectal cancer of metastatic colorectal cancer

Author keywords

Antibiotics; Cetuximab; Epidermal growth factor; Immunomodulatory agents; Rash; Steroids

Indexed keywords

ADRENALIN; ANTIBIOTIC AGENT; ANTIHISTAMINIC AGENT; BEVACIZUMAB; CETIRIZINE; CETUXIMAB; CLINDAMYCIN; CLOBETASOL PROPIONATE; CORTICOSTEROID; CYTOTOXIC AGENT; DOXYCYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; ERYTHROMYCIN; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; FOLINIC ACID; HISTAMINE H1 RECEPTOR ANTAGONIST; HYDROXYZINE; IMMUNOMODULATING AGENT; IRINOTECAN; LORATADINE; METRONIDAZOLE; OXALIPLATIN; PANITUMUMAB; PSEUDOMONIC ACID; RETINOID; STEROID; TETRACYCLINE; UNINDEXED DRUG;

EID: 33749032101     PISSN: 15330028     EISSN: None     Source Type: Journal    
DOI: 10.3816/CCC.2006.n.028     Document Type: Review
Times cited : (40)

References (38)
  • 1
    • 0037296357 scopus 로고    scopus 로고
    • The epidermal growth factor receptor-tyrosine kinase: Promising therapeutic target in solid tumors
    • Ritter CA, Arteage CL. The epidermal growth factor receptor-tyrosine kinase: promising therapeutic target in solid tumors. Semin Oncol 2003; 30:3-11.
    • (2003) Semin Oncol , vol.30 , pp. 3-11
    • Ritter, C.A.1    Arteage, C.L.2
  • 2
    • 0037106273 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor for cancer therapy
    • Mendelsohn J. Targeting the epidermal growth factor receptor for cancer therapy. J Clin Oncol 2002; 20(18 suppl):1s-13s.
    • (2002) J Clin Oncol , vol.20 , Issue.18 SUPPL.
    • Mendelsohn, J.1
  • 3
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Bonner JA, Harari, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. New Engl J Med 2006; 354:567-578.
    • (2006) New Engl J Med , vol.354 , pp. 567-578
    • Bonner, J.A.1    Harari2    Giralt, J.3
  • 4
    • 2142641698 scopus 로고    scopus 로고
    • Phase II Trial of cetuximab in patients with refractory colorectal cancer that express the epidermal growth factor receptor
    • Saltz L, Meropol N, Loehrer PJ, et al. Phase II Trial of cetuximab in patients with refractory colorectal cancer that express the epidermal growth factor receptor. J Clin Oncol 2004; 22:1201-1208.
    • (2004) J Clin Oncol , vol.22 , pp. 1201-1208
    • Saltz, L.1    Meropol, N.2    Loehrer, P.J.3
  • 5
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004;351:337-345.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 6
    • 0347187211 scopus 로고    scopus 로고
    • Cetuximab in combination with biweekly irinotecan, infusional 5-fluorouracil and folinic acid in patients with metastatic colorectal cancer expressing the epidermal growth factor receptor. Preliminary safety and efficacy results
    • (Abstract #1058)
    • Van Laethem JL, Raoul JL, Mitry E, et al. Cetuximab in combination with biweekly irinotecan, infusional 5-fluorouracil and folinic acid in patients with metastatic colorectal cancer expressing the epidermal growth factor receptor. Preliminary safety and efficacy results. Proc Am Soc Clin Oncol 2003; 22:264 (Abstract #1058).
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 264
    • Van Laethem, J.L.1    Raoul, J.L.2    Mitry, E.3
  • 7
    • 19244366949 scopus 로고    scopus 로고
    • Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
    • Baselga J, Pfister D, Cooper MR, et al. Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin. J Clin Oncol 2000; 18:904-914.
    • (2000) J Clin Oncol , vol.18 , pp. 904-914
    • Baselga, J.1    Pfister, D.2    Cooper, M.R.3
  • 8
    • 0001355931 scopus 로고    scopus 로고
    • Low immunogenicity of a chimeric monoclonal antibody (MAb), IMC-C225, used to treat epidermal growth factor receptor-positive tumors
    • (Abstract #808)
    • Khazaeli MB, LoBuglio AF, Falcey JW, et al. Low immunogenicity of a chimeric monoclonal antibody (MAb), IMC-C225, used to treat epidermal growth factor receptor-positive tumors. Proc Am Soc Clin Oncol 2000; 19:207a (Abstract #808).
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • Khazaeli, M.B.1    LoBuglio, A.F.2    Falcey, J.W.3
  • 9
    • 0035117355 scopus 로고    scopus 로고
    • Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer chemotherapy
    • Yang XD, Xiao-Chi J, Corvalan JRF, et al. Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer chemotherapy. Crit Rev Oncol Hematol 2001; 38:17-23.
    • (2001) Crit Rev Oncol Hematol , vol.38 , pp. 17-23
    • Yang, X.D.1    Xiao-Chi, J.2    Corvalan, J.R.F.3
  • 10
    • 0036118248 scopus 로고    scopus 로고
    • Therapeutic potential of ABX-EGF: A fully human anti-epidermal growth factor receptor monoclonal antibody for cancer treatment
    • Lynch DH, Yang XD. Therapeutic potential of ABX-EGF: a fully human anti-epidermal growth factor receptor monoclonal antibody for cancer treatment. Semin Oncol 2002; 29(suppl 4):47-50.
    • (2002) Semin Oncol , vol.29 , Issue.SUPPL. 4 , pp. 47-50
    • Lynch, D.H.1    Yang, X.D.2
  • 11
    • 0242293804 scopus 로고    scopus 로고
    • ABX-EGF, a fully human anti-EGF receptor monoclonal antibody: Inhibition of prostate cancer in vitro and in vivo
    • (Abstract #2454)
    • Yang XD, Wang P, Fredlin P, et al. ABX-EGF, a fully human anti-EGF receptor monoclonal antibody: inhibition of prostate cancer in vitro and in vivo. Proc Am Soc Clin Oncol 2002; 21:160b (Abstract #2454).
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Yang, X.D.1    Wang, P.2    Fredlin, P.3
  • 12
    • 0142149729 scopus 로고    scopus 로고
    • Therapeutic potential of ABX-EGF, fully human anti-EGF receptor monoclonal antibody, for the treatment of renal cell carcinoma
    • (Abstract #761)
    • Wang P, Fredlin P, Davis CG, et al. Therapeutic potential of ABX-EGF, fully human anti-EGF receptor monoclonal antibody, for the treatment of renal cell carcinoma. Proc Am Soc Clin Oncol 2002; 21:191a (Abstract #761).
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Wang, P.1    Fredlin, P.2    Davis, C.G.3
  • 13
    • 0000568621 scopus 로고    scopus 로고
    • Phase 2 clinical trial evaluating the safety and effectiveness of ABX-EGF in renal cell cancer (RCC)
    • (Abstract #91)
    • Schwartz G, Dutcher JP, Vogelzang NJ, et al. Phase 2 clinical trial evaluating the safety and effectiveness of ABX-EGF in renal cell cancer (RCC). Proc Am Soc Clin Oncol 2002; 21:24a (Abstract #91).
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Schwartz, G.1    Dutcher, J.P.2    Vogelzang, N.J.3
  • 14
    • 0012679970 scopus 로고    scopus 로고
    • ABX-EGF, a fully human anti-epidermal growth factor receptor (EGFR) monoclonal antibody (MAb) in patients with advanced cancer: Phase 1 clinical results
    • (Abstract #35)
    • Figlin RA, Belldegrun AS, Crawford J, et al. ABX-EGF, a fully human anti-epidermal growth factor receptor (EGFR) monoclonal antibody (MAb) in patients with advanced cancer: phase 1 clinical results. Proc Am Soc Clin Oncol 2002; 21:10a (Abstract #35).
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Figlin, R.A.1    Belldegrun, A.S.2    Crawford, J.3
  • 15
    • 6344272498 scopus 로고    scopus 로고
    • ABX-EGF monotherapy in patients with metastatic colorectal cancer (mCRC): An updated analysis
    • (Abstract #3511)
    • Hecht R, Patnaik A, Malik I, et al. ABX-EGF monotherapy in patients with metastatic colorectal cancer (mCRC): an updated analysis. Proc Am Soc Clin Oncol 2004; 23:248 (Abstract #3511).
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 248
    • Hecht, R.1    Patnaik, A.2    Malik, I.3
  • 16
    • 4444368283 scopus 로고    scopus 로고
    • ABX-EGF in combination with paclitaxel and carboplatin for advanced non-small cell lung cancer (NSCLC)
    • (Abstract #7083)
    • Crawford J, Sandler AB, Hammond LA, et al. ABX-EGF in combination with paclitaxel and carboplatin for advanced non-small cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 2004; 23:634 (Abstract #7083).
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 634
    • Crawford, J.1    Sandler, A.B.2    Hammond, L.A.3
  • 17
    • 4143050397 scopus 로고    scopus 로고
    • Safety, pharmacokinetics and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer
    • Rowinsky E, Schwartz GH, Gollob JA, et al. Safety, pharmacokinetics and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer. J Clin Oncol 2004; 22:3003-3015.
    • (2004) J Clin Oncol , vol.22 , pp. 3003-3015
    • Rowinsky, E.1    Schwartz, G.H.2    Gollob, J.A.3
  • 18
    • 33244488713 scopus 로고    scopus 로고
    • Updated results from a dose and schedule study of panitumumab (ABX-EGF) monotherapy in patients with advanced solid malignancies
    • (Abstract #3059)
    • Weiner LM, Belldegrun A, Rowinsky E, et al. Updated results from a dose and schedule study of panitumumab (ABX-EGF) monotherapy in patients with advanced solid malignancies. J Clin Oncol 2005; 23(16 suppl):206s (Abstract #3059).
    • (2005) J Clin Oncol , vol.23 , Issue.16 SUPPL.
    • Weiner, L.M.1    Belldegrun, A.2    Rowinsky, E.3
  • 19
    • 23844454976 scopus 로고    scopus 로고
    • Safety and efficacy of panitumumab monotherapy in patients with metastatic colorectal cancer
    • (Abstract #3520)
    • Malik I, Hecht JR, Patnaik A, et al. Safety and efficacy of panitumumab monotherapy in patients with metastatic colorectal cancer. J Clin Oncol 2005; 23(16 suppl):251s (Abstract #3520).
    • (2005) J Clin Oncol , vol.23 , Issue.16 SUPPL.
    • Malik, I.1    Hecht, J.R.2    Patnaik, A.3
  • 20
    • 33845644223 scopus 로고    scopus 로고
    • Panitumumab therapy with irinotecan, 5-fluorouracil, and leukovorin (IFL) in metastatic colorectal patients: A pharmacokinetic analysis
    • Presented at: January 27-29, Hotlywood, FL. Abstract #259
    • Hecht JR, Berlin J, Malik I, et al. Panitumumab therapy with irinotecan, 5-fluorouracil, and leukovorin (IFL) in metastatic colorectal patients: a pharmacokinetic analysis. Presented at: American Society of Clinical Oncology Gastrointestinal Cancers Symposium; January 27-29, 2005; Hotlywood, FL. Abstract #259.
    • (2005) American Society of Clinical Oncology Gastrointestinal Cancers Symposium
    • Hecht, J.R.1    Berlin, J.2    Malik, I.3
  • 21
    • 28444447161 scopus 로고    scopus 로고
    • Panitumumab therapy with irinotecan, 5-fluorouracil, and leukovorin (IFL) in metastatic colorectal patients
    • (Abstract #265PD)
    • Berlin J, Malik I, Picus J. Panitumumab therapy with irinotecan, 5-fluorouracil, and leukovorin (IFL) in metastatic colorectal patients. Ann Oncol 2004; 15(suppl 3):iii70 (Abstract #265PD).
    • (2004) Ann Oncol , vol.15 , Issue.SUPPL. 3
    • Berlin, J.1    Malik, I.2    Picus, J.3
  • 22
    • 33749015088 scopus 로고    scopus 로고
    • A phase 3, multicenter, randomized controlled trial of panitumumab plus best supportive care (BSC) vs. BSC alone in patients with metastatic colorectal cancer
    • Presented at the April 1-5, Washington, DC. Abstract #CP-1
    • Peeters M, Van Cutsem E, Siena S, et al. A phase 3, multicenter, randomized controlled trial of panitumumab plus best supportive care (BSC) vs. BSC alone in patients with metastatic colorectal cancer. Presented at the 97th Annual Meeting of the American Association of Cancer Research, April 1-5, 2006; Washington, DC. Abstract #CP-1.
    • (2006) 97th Annual Meeting of the American Association of Cancer Research
    • Peeters, M.1    Van Cutsem, E.2    Siena, S.3
  • 23
    • 84898696294 scopus 로고    scopus 로고
    • PACCE: A randomized, open-label, controlled, clinical trial of chemotherapy and bevacizumab with and without Panitumumab in the first-line treatment of subjects with metastatic colorectal cancer
    • National Cancer Institute Web site. Available at: Accessed May 6
    • PACCE: a randomized, open-label, controlled, clinical trial of chemotherapy and bevacizumab with and without Panitumumab in the first-line treatment of subjects with metastatic colorectal cancer. National Cancer Institute Web site. Available at: www.clinicaltrials. gov.ct/show/NCT00115765. Accessed May 6, 2006.
    • (2006)
  • 24
    • 84898697483 scopus 로고    scopus 로고
    • An open-label, dose-finding study to evaluate the safety of AMG 706 plus panitumumab plus chemotherapy in the treatment of subjects with metastatic colorectal cancer
    • National Cancer Institute Web site. Available at: Accessed May 6
    • An open-label, dose-finding study to evaluate the safety of AMG 706 plus panitumumab plus chemotherapy in the treatment of subjects with metastatic colorectal cancer. National Cancer Institute Web site. Available at: www.clinicaltrials.gov.ct/show/NCT00115765. Accessed May 6, 2006.
    • (2006)
  • 25
    • 33748994977 scopus 로고    scopus 로고
    • Panitumumab antitumor activity inpatients with metastatic colorectal cancer expressing low (1-9%) or negative levels of EGFR
    • (Abstract #3547)
    • Hecht J, Mitchell E, Barada J, et al. Panitumumab antitumor activity inpatients with metastatic colorectal cancer expressing low (1-9%) or negative levels of EGFR. J Clin Oncol 2006; 24(18 suppl):157s (Abstract #3547).
    • (2006) J Clin Oncol , vol.24 , Issue.18 SUPPL.
    • Hecht, J.1    Mitchell, E.2    Barada, J.3
  • 26
    • 33748994720 scopus 로고    scopus 로고
    • Panitumumab antitumor activity in patients with metastatic colorectal cancer expressing greater than 10% EGFR
    • (Abstract #3548)
    • Berlin J, Neubauer M, Swanson P, et al. Panitumumab antitumor activity in patients with metastatic colorectal cancer expressing greater than 10% EGFR. J Clin Oncol 2006; 24(18 suppl):158s (Abstract #3548).
    • (2006) J Clin Oncol , vol.24 , Issue.18 SUPPL.
    • Berlin, J.1    Neubauer, M.2    Swanson, P.3
  • 27
    • 33749028607 scopus 로고    scopus 로고
    • Flexible dosing schedules of panintimumab (ABX-EGF) in cancer patients
    • (Abstract #3089)
    • Arends R, Yang B. Flexible dosing schedules of panintimumab (ABX-EGF) in cancer patients. J Clin Oncol 2005; 25(16 suppl):214s (Abstract #3089).
    • (2005) J Clin Oncol , vol.25 , Issue.16 SUPPL.
    • Arends, R.1    Yang, B.2
  • 28
    • 33847694798 scopus 로고    scopus 로고
    • Panitumumab in combination with irinotecan, 5-fluorouracil, and leukovorin (IFL) or FOLFIRI for first-fine treatment of metastatic colorectal cancer
    • Presented at: January 26-28, San Francisco, CA. Abstract #237
    • Hecht J, Posey J, Tchekmedyian S, et al. Panitumumab in combination with irinotecan, 5-fluorouracil, and leukovorin (IFL) or FOLFIRI for first-fine treatment of metastatic colorectal cancer. Presented at: American Society of Clinical Oncology Gastrointestinal Cancers Symposium; January 26-28, 2006; San Francisco, CA. Abstract #237.
    • (2006) American Society of Clinical Oncology Gastrointestinal Cancers Symposium
    • Hecht, J.1    Posey, J.2    Tchekmedyian, S.3
  • 29
    • 84898701612 scopus 로고    scopus 로고
    • Erbitux® (cetuximab) [package insert]. New York, NY: ImClone Systems Incorporated, and Princeton, NJ: Bristol-Myers Squibb Company; August
    • Erbitux® (cetuximab) [package insert]. New York, NY: ImClone Systems Incorporated, and Princeton, NJ: Bristol-Myers Squibb Company; August 2005.
    • (2005)
  • 30
    • 23844555670 scopus 로고    scopus 로고
    • Cetuximab therapy and symptomatic hypomagnesemia
    • Schrag D, Chung KY, Flombaum C, et al. Cetuximab therapy and symptomatic hypomagnesemia. J Natl Cancer Inst 2005;97:1221-1224.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1221-1224
    • Schrag, D.1    Chung, K.Y.2    Flombaum, C.3
  • 31
    • 0038080138 scopus 로고    scopus 로고
    • Dermatologic side effects associated with gefitinib therapy: Clinical experience and management
    • Herbst RS, Lorusso PM, Purdom M, et al. Dermatologic side effects associated with gefitinib therapy: clinical experience and management. Clin Lung Cancer 2003; 4:366-369.
    • (2003) Clin Lung Cancer , vol.4 , pp. 366-369
    • Herbst, R.S.1    Lorusso, P.M.2    Purdom, M.3
  • 32
    • 20844448897 scopus 로고    scopus 로고
    • HER1/EGFR inhibitor-associated rash future directions for management and investigation outcomes from the HER1/EGFR inhibitor rash management forum
    • Pérez-Soler R, Delord JP, Halpern A, et al. HER1/EGFR inhibitor-associated rash future directions for management and investigation outcomes from the HER1/EGFR inhibitor rash management forum. Oncologist 2005; 10:345-356.
    • (2005) Oncologist , vol.10 , pp. 345-356
    • Pérez-Soler, R.1    Delord, J.P.2    Halpern, A.3
  • 33
    • 27744498271 scopus 로고    scopus 로고
    • Cetuximab-associated acneiform eruption
    • Moss JE, Burtness B. Cetuximab-associated acneiform eruption. N Engl J Med 2005; 353:e17.
    • (2005) N Engl J Med , vol.353
    • Moss, J.E.1    Burtness, B.2
  • 34
    • 4043133757 scopus 로고    scopus 로고
    • Acneiform eruption induced by epidermal growth factor receptor inhibitors in patients with solid tumours
    • Jacot W, Bessis D, Jorda E, et al. Acneiform eruption induced by epidermal growth factor receptor inhibitors in patients with solid tumours. Br J Dermatol 2004; 151:238-241.
    • (2004) Br J Dermatol , vol.151 , pp. 238-241
    • Jacot, W.1    Bessis, D.2    Jorda, E.3
  • 35
    • 16644369733 scopus 로고    scopus 로고
    • Practical management of patients with non-small-cell lung cancer treated with gefitinib
    • Shah NT, Kris MG, Pao W, et al. Practical management of patients with non-small-cell lung cancer treated with gefitinib. J Clin Oncol 2005; 23:165-174.
    • (2005) J Clin Oncol , vol.23 , pp. 165-174
    • Shah, N.T.1    Kris, M.G.2    Pao, W.3
  • 36
    • 33645785843 scopus 로고    scopus 로고
    • Common side effects of anti-EGFR therapy: Acneform. rash
    • Sipples R. Common side effects of anti-EGFR therapy: acneform. rash. Semin Oncol Nurs 2006; 22(1 suppl 1):28-34.
    • (2006) Semin Oncol Nurs , vol.22 , Issue.1 SUPPL. 1 , pp. 28-34
    • Sipples, R.1
  • 37
    • 33644665064 scopus 로고    scopus 로고
    • Management of rash and other toxicities in patients treated with epidermal growth factor receptor-targeted agents
    • Rhee J, Oishi K, Garey J, et al. Management of rash and other toxicities in patients treated with epidermal growth factor receptor-targeted agents. Clin Colorectal Cancer 2005; 5(suppl 2):S101-S106.
    • (2005) Clin Colorectal Cancer , vol.5 , Issue.SUPPL. 2
    • Rhee, J.1    Oishi, K.2    Garey, J.3
  • 38
    • 0036051312 scopus 로고    scopus 로고
    • Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor
    • Van Doorn R, Kirtschig G, Scheffer E, et al. Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor. Br J Dermatol 2002; 147:598-601.
    • (2002) Br J Dermatol , vol.147 , pp. 598-601
    • Van Doorn, R.1    Kirtschig, G.2    Scheffer, E.3


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