메뉴 건너뛰기




Volumn 65, Issue , 2011, Pages 169-188

Prospects for the future using genomics and proteomics in clinical microbiology

Author keywords

Antibiotic susceptibility; Culture; Diagnosis; Genome sequence; Proteome; Vaccine

Indexed keywords

DNA VACCINE; HEPATITIS C VACCINE; OXAZOLIDINONE DERIVATIVE; PROTEOME; PYRIMIDINONE DERIVATIVE; VIRULENCE FACTOR;

EID: 80053226102     PISSN: 00664227     EISSN: 15453251     Source Type: Book Series    
DOI: 10.1146/annurev-micro-090110-102922     Document Type: Review
Times cited : (53)

References (163)
  • 3
    • 65549169558 scopus 로고    scopus 로고
    • The expansion of the microbiological spectrum of brain abscesses with use of multiple 16S ribosomal DNA sequencing
    • Al Masalma M, Armougom F, Scheld WM, Dufour H, Roche PH, et al. 2009. The expansion of the microbiological spectrum of brain abscesses with use of multiple 16S ribosomal DNA sequencing. Clin. Infect. Dis. 48:1169-78
    • (2009) Clin. Infect. Dis. , vol.48 , pp. 1169-78
    • Al Masalma, M.1    Armougom, F.2    Scheld, W.M.3    Dufour, H.4    Roche, P.H.5
  • 5
    • 0030990021 scopus 로고    scopus 로고
    • Simple, speedy, sensitive, and specific serodiagnosis of pertussis by using a particle agglutination test
    • Aoyama T, Kato T, Takeuchi Y, Kato K, Morokuma K, Hirai T. 1997. Simple, speedy, sensitive, and specific serodiagnosis of pertussis by using a particle agglutination test. J. Clin. Microbiol. 35:1859-61 (Pubitemid 27255675)
    • (1997) Journal of Clinical Microbiology , vol.35 , Issue.7 , pp. 1859-1861
    • Aoyama, T.1    Kato, T.2    Takeuchi, Y.3    Kato, K.4    Morokuma, K.5    Hirai, T.6
  • 8
    • 70349631208 scopus 로고    scopus 로고
    • Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and methanogens in anorexic patients
    • Armougom F, Henry M, Vialettes B, Raccah D, Raoult D. 2009. Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and methanogens in anorexic patients. PLoS One 4:e7125
    • (2009) PLoS One , vol.4
    • Armougom, F.1    Henry, M.2    Vialettes, B.3    Raccah, D.4    Raoult, D.5
  • 9
    • 58349108870 scopus 로고    scopus 로고
    • Use of pyrosequencing and DNA barcodes to monitor variations in Firmicutes and Bacteroidetes communities in the gut microbiota of obese humans
    • Armougom F, Raoult D. 2008. Use of pyrosequencing and DNA barcodes to monitor variations in Firmicutes and Bacteroidetes communities in the gut microbiota of obese humans. BMC Genomics 9:576
    • (2008) BMC Genomics , vol.9 , pp. 576
    • Armougom, F.1    Raoult, D.2
  • 11
    • 61649121489 scopus 로고    scopus 로고
    • The use of genomics in microbial vaccine development
    • Bambini S, Rappuoli R. 2009. The use of genomics in microbial vaccine development. Drug Discov. Today 14:252-60
    • (2009) Drug Discov. Today , vol.14 , pp. 252-60
    • Bambini, S.1    Rappuoli, R.2
  • 13
    • 0036203123 scopus 로고    scopus 로고
    • Genome scale comparison of Mycobacterium avium subsp. paratuberculosis with Mycobacterium avium subsp. avium reveals potential diagnostic sequences
    • DOI 10.1128/JCM.40.4.1303-1310.2002
    • Bannantine JP, Baechler E, Zhang Q, Li L, Kapur V. 2002. Genome scale comparison of Mycobacterium avium subsp. paratuberculosis with Mycobacterium avium subsp. avium reveals potential diagnostic sequences. J. Clin. Microbiol. 40:1303-10 (Pubitemid 34279893)
    • (2002) Journal of Clinical Microbiology , vol.40 , Issue.4 , pp. 1303-1310
    • Bannantine, J.P.1    Baechler, E.2    Zhang, Q.3    Li, L.4    Kapur, V.5
  • 15
    • 33847753497 scopus 로고    scopus 로고
    • Mycobacterial virulence and specialized secretion: Same story, different ending
    • DOI 10.1038/nm0307-286, PII NM0307286
    • Behr MA, Sherman DR. 2007. Mycobacterial virulence and specialized secretion: same story, different ending. Nat. Med. 13:286-87 (Pubitemid 46376671)
    • (2007) Nature Medicine , vol.13 , Issue.3 , pp. 286-287
    • Behr, M.A.1    Sherman, D.R.2
  • 17
    • 33646478851 scopus 로고    scopus 로고
    • Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus
    • Beres SB, Richter EW, Nagiec MJ, Sumby P, Porcella SF, et al. 2006. Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus. Proc. Natl. Acad. Sci. USA 103:7059-64
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7059-64
    • Beres, S.B.1    Richter, E.W.2    Nagiec, M.J.3    Sumby, P.4    Porcella, S.F.5
  • 20
    • 33746642628 scopus 로고    scopus 로고
    • From functional genomics to functional immunomics: New challenges, old problems, big rewards
    • Braga-Neto UM, Marques ET Jr. 2006. From functional genomics to functional immunomics: new challenges, old problems, big rewards. PLoS Comput. Biol. 2:e81
    • (2006) PLoS Comput. Biol. , vol.2
    • Braga-Neto, U.M.1    Marques, Jr.E.T.2
  • 22
    • 0037830766 scopus 로고    scopus 로고
    • Genome-wide DNA microarray analysis of Francisella tularensis strains demonstrates extensive genetic conservation within the species but identifies regions that are unique to the highly virulent F. tularensis subsp. tularensis
    • DOI 10.1128/JCM.41.7.2924-2931.2003
    • Broekhuijsen M, Larsson P, Johansson A, Bystrom M, Eriksson U, et al. 2003. Genome-wide DNA microarray analysis of Francisella tularensis strains demonstrates extensive genetic conservation within the species but identifies regions that are unique to the highly virulent F. tularensis subsp. tularensis. J. Clin. Microbiol. 41:2924-31 (Pubitemid 36842280)
    • (2003) Journal of Clinical Microbiology , vol.41 , Issue.7 , pp. 2924-2931
    • Broekhuijsen, M.1    Larsson, P.2    Johansson, A.3    Bystrom, M.4    Eriksson, U.5    Larsson, E.6    Prior, R.G.7    Sjostedt, A.8    Titball, R.W.9    Forsman, M.10
  • 23
    • 0842348309 scopus 로고    scopus 로고
    • Chips with everything: DNA microarrays in infectious diseases
    • DOI 10.1016/S1473-3099(04)00930-2
    • Bryant PA, Venter D, Robins-Browne R, Curtis N. 2004. Chips with everything: DNA microarrays in infectious diseases. Lancet Infect. Dis. 4:100-11 (Pubitemid 38169277)
    • (2004) Lancet Infectious Diseases , vol.4 , Issue.2 , pp. 100-111
    • Bryant, P.A.1    Venter, D.2    Robins-Browne, R.3    Curtis, N.4
  • 25
    • 0041734645 scopus 로고    scopus 로고
    • Mycobacterial interspersed repetitive units (MIRU) differentiate Mycobacterium avium subspecies paratuberculosis from other species of the Mycobacterium avium complex
    • DOI 10.1016/S0890-8508(03)00047-1
    • Bull TJ, Sidi-BoumedineK,McMinnEJ, StevensonK, Pickup R, Hermon-Taylor J. 2003. Mycobacterial interspersed repetitive units (MIRU) differentiate Mycobacterium avium subspecies paratuberculosis from other species of the Mycobacterium avium complex. Mol. Cell Probes 17:157-64 (Pubitemid 36999812)
    • (2003) Molecular and Cellular Probes , vol.17 , Issue.4 , pp. 157-164
    • Bull, T.J.1    Sidi-Boumedine, K.2    McMinn, E.J.3    Stevenson, K.4    Pickup, R.5    Hermon-Taylor, J.6
  • 28
    • 25444493846 scopus 로고    scopus 로고
    • Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains
    • DOI 10.1128/IAI.73.10.6407-6418.2005
    • Carlson JH, Porcella SF,McClarty G, Caldwell HD. 2005. Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains. Infect. Immun. 73:6407-18 (Pubitemid 41368802)
    • (2005) Infection and Immunity , vol.73 , Issue.10 , pp. 6407-6418
    • Carlson, J.H.1    Porcella, S.F.2    McClarty, G.3    Caldwell, H.D.4
  • 29
    • 2442532564 scopus 로고    scopus 로고
    • Revisiting the pestilence of Helicobacter pylori: Insights into geographical genomics and pathogen evolution
    • DOI 10.1016/j.meegid.2004.01.006, PII S1567134804000085
    • Carroll IM, Khan AA, Ahmed N. 2004. Revisiting the pestilence of Helicobacter pylori: insights into geographical genomics and pathogen evolution. Infect. Genet. Evol. 4:81-90 (Pubitemid 38647291)
    • (2004) Infection, Genetics and Evolution , vol.4 , Issue.2 , pp. 81-90
    • Carroll, I.M.1    Khan, A.A.2    Ahmed, N.3
  • 30
    • 0034101261 scopus 로고    scopus 로고
    • Proteomics in medical microbiology
    • DOI 10.1002/(SICI)1522-2683(20000401)21:6<1187::AID-ELPS1187>3.0. CO;2-F
    • Cash P. 2000. Proteomics in medical microbiology. Electrophoresis 21:1187-201 (Pubitemid 30230783)
    • (2000) Electrophoresis , vol.21 , Issue.6 , pp. 1187-1201
    • Cash, P.1
  • 31
    • 79952180032 scopus 로고    scopus 로고
    • Universal vaccines: Shifting to one for many
    • Cassone A, Rappuoli R. 2010. Universal vaccines: shifting to one for many. MBio 1(1):e00042-10
    • (2010) MBio , vol.1 , Issue.1
    • Cassone, A.1    Rappuoli, R.2
  • 33
    • 33645827531 scopus 로고    scopus 로고
    • Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: A comparative genomics approach
    • Chen SL,Hung CS, Xu J, Reigstad CS,Magrini V, et al. 2006. Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. Proc. Natl. Acad. Sci. USA 103:5977-82
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 5977-82
    • Chen, S.L.1    Hung, C.S.2    Xu, J.3    Reigstad, C.S.4    Magrini, V.5
  • 36
    • 5644227319 scopus 로고    scopus 로고
    • Impact of 16S rRNA gene sequence analysis for identification of bacteria on clinical microbiology and infectious diseases
    • Clarridge JE III. 2004. Impact of 16S rRNA gene sequence analysis for identification of bacteria on clinical microbiology and infectious diseases. Clin. Microbiol. Rev. 17:840-62
    • (2004) Clin. Microbiol. Rev. , vol.17 , pp. 840-62
    • Clarridge Iii, J.E.1
  • 37
    • 0036892186 scopus 로고    scopus 로고
    • Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics
    • DOI 10.1128/IAI.70.12.6996-7003.2002
    • Cockle PJ, Gordon SV, Lalvani A, Buddle BM, Hewinson RG, Vordermeier HM. 2002. Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics. Infect. Immun. 70:6996-7003 (Pubitemid 35387935)
    • (2002) Infection and Immunity , vol.70 , Issue.12 , pp. 6996-7003
    • Cockle, P.J.1    Gordon, S.V.2    Lalvani, A.3    Buddle, B.M.4    Hewinson, R.G.5    Vordermeier, H.M.6
  • 41
    • 0034753350 scopus 로고    scopus 로고
    • Genome sequence-based fluorescent amplified fragment length polymorphism of Campylobacter jejuni, its relationship to serotyping, and its implications for epidemiological analysis
    • DOI 10.1128/JCM.39.11.3823-3829.2001
    • Desai M, Logan JM, Frost JA, Stanley J. 2001. Genome sequence-based fluorescent amplified fragment length polymorphism of Campylobacter jejuni, its relationship to serotyping, and its implications for epidemiological analysis. J. Clin. Microbiol. 39:3823-29 (Pubitemid 33029746)
    • (2001) Journal of Clinical Microbiology , vol.39 , Issue.11 , pp. 3823-3829
    • Desai, M.1    Logan, J.M.J.2    Frost, J.A.3    Stanley, J.4
  • 42
    • 34248159346 scopus 로고    scopus 로고
    • High-density universal 16S rRNA microarray analysis reveals broader diversity than typical clone library when sampling the environment
    • DOI 10.1007/s00248-006-9134-9
    • Desantis TZ, Brodie EL, Moberg JP, Zubieta IX, Piceno YM, Andersen GL. 2007. High-density universal 16S rRNA microarray analysis reveals broader diversity than typical clone library when sampling the environment. Microb. Ecol. 53:371-83 (Pubitemid 46716624)
    • (2007) Microbial Ecology , vol.53 , Issue.3 , pp. 371-383
    • DeSantis, T.Z.1    Brodie, E.L.2    Moberg, J.P.3    Zubieta, I.X.4    Piceno, Y.M.5    Andersen, G.L.6
  • 43
    • 2442449227 scopus 로고    scopus 로고
    • Genomic islands in pathogenic and environmental microorganisms
    • DOI 10.1038/nrmicro884
    • Dobrindt U, HochhutB,Hentschel U, Hacker J. 2004. Genomic islands in pathogenic and environmental microorganisms. Nat. Rev. Microbiol. 2:414-24 (Pubitemid 39490120)
    • (2004) Nature Reviews Microbiology , vol.2 , Issue.5 , pp. 414-424
    • Dobrindt, U.1    Hochhut, B.2    Hentschel, U.3    Hacker, J.4
  • 44
    • 0033796860 scopus 로고    scopus 로고
    • A postgenomic approach to identification of Mycobacterium leprae-specific peptides as T-cell reagents
    • Dockrell HM, Brahmbhatt S, Robertson BD, Britton S, Fruth U, et al. 2000. A postgenomic approach to identification of Mycobacterium leprae-specific peptides as T-cell reagents. Infect. Immun. 68:5846-55
    • (2000) Infect. Immun. , vol.68 , pp. 5846-55
    • Dockrell, H.M.1    Brahmbhatt, S.2    Robertson, B.D.3    Britton, S.4    Fruth, U.5
  • 47
    • 0035125986 scopus 로고    scopus 로고
    • In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data
    • DOI 10.1038/84379
    • Edwards JS, Ibarra RU, Palsson BO. 2001. In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat. Biotechnol. 19:125-30 (Pubitemid 32144439)
    • (2001) Nature Biotechnology , vol.19 , Issue.2 , pp. 125-130
    • Edwards, J.S.1    Ibarra, R.U.2    Palsson, B.O.3
  • 48
    • 0036136317 scopus 로고    scopus 로고
    • Comparison of real-time, quantitative PCR with molecular beacons to nested PCR and culture methods for detection of Mycobacterium avium subsp. paratuberculosis in bovine fecal samples
    • DOI 10.1128/JCM.40.1.287-291.2002
    • Fang Y, Wu WH, Pepper JL, Larsen JL, Marras SA, et al. 2002. Comparison of real-time, quantitative PCR with molecular beacons to nested PCR and culture methods for detection of Mycobacterium avium subsp. paratuberculosis in bovine fecal samples. J. Clin. Microbiol. 40:287-91 (Pubitemid 34030564)
    • (2002) Journal of Clinical Microbiology , vol.40 , Issue.1 , pp. 287-291
    • Fang, Y.1    Wu, W.-H.2    Pepper, J.L.3    Larsen, J.L.4    Marras, S.A.E.5    Nelson, E.A.6    Epperson, W.B.7    Christopher-Hennings, J.8
  • 50
    • 0029653518 scopus 로고
    • Whole-genome random sequencing and assembly of Haemophilus influenzae Rd
    • Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, et al. 1995. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:496-512
    • (1995) Science , vol.269 , pp. 496-512
    • Fleischmann, R.D.1    Adams, M.D.2    White, O.3    Clayton, R.A.4    Kirkness, E.F.5
  • 52
    • 35349014651 scopus 로고    scopus 로고
    • Bacterial genome sequencing and its use in infectious diseases
    • DOI 10.1016/S1473-3099(07)70260-8, PII S1473309907702608
    • Fournier PE, Drancourt M, Raoult D. 2007. Bacterial genome sequencing and its use in infectious diseases. Lancet Infect. Dis. 7:711-23 (Pubitemid 47600091)
    • (2007) Lancet Infectious Diseases , vol.7 , Issue.11 , pp. 711-723
    • Fournier, P.-E.1    Drancourt, M.2    Raoult, D.3
  • 53
    • 67649111863 scopus 로고    scopus 로고
    • Analysis of the Rickettsia africae genome reveals that virulence acquisition in Rickettsia species may be explained by genome reduction
    • Fournier PE, El KK, Leroy Q, Robert C, Giumelli B, et al. 2009. Analysis of the Rickettsia africae genome reveals that virulence acquisition in Rickettsia species may be explained by genome reduction. BMC Genomics 10:166
    • (2009) BMC Genomics , vol.10 , pp. 166
    • Fournier, P.E.1    El, K.K.2    Leroy, Q.3    Robert, C.4    Giumelli, B.5
  • 54
    • 3843086250 scopus 로고    scopus 로고
    • Suicide PCR on skin biopsy specimens for diagnosis of Rickettsioses
    • DOI 10.1128/JCM.42.8.3428-3434.2004
    • Fournier PE, Raoult D. 2004. Suicide PCR on skin biopsy specimens for diagnosis of rickettsioses. J. Clin. Microbiol. 42:3428-34 (Pubitemid 39045661)
    • (2004) Journal of Clinical Microbiology , vol.42 , Issue.8 , pp. 3428-3434
    • Fournier, P.-E.1    Raoult, D.2
  • 56
    • 33144490023 scopus 로고    scopus 로고
    • Comparative genomics of multidrug resistance in Acinetobacter baumannii
    • Fournier PE, Vallenet D, Barbe V, Audic S, Ogata H, et al. 2006. Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet. 2:e7
    • (2006) PLoS Genet. , vol.2
    • Fournier, P.E.1    Vallenet, D.2    Barbe, V.3    Audic, S.4    Ogata, H.5
  • 57
    • 20044387762 scopus 로고    scopus 로고
    • Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species
    • Fouts DE, Mongodin EF, Mandrell RE,MillerWG, Rasko DA, et al. 2005. Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species. PLoS Biol. 3:e15
    • (2005) PLoS Biol. , vol.3
    • Fouts, D.E.1    Mongodin, E.F.2    Mandrell, R.E.3    Miller, W.G.4    Rasko, D.A.5
  • 59
    • 14544284148 scopus 로고    scopus 로고
    • Application of microbial genomic science to advanced therapeutics
    • DOI 10.1146/annurev.med.56.062904.144853
    • Fraser CM, Rappuoli R. 2005. Application ofmicrobial genomic science to advanced therapeutics. Annu. Rev. Med. 56:459-74 (Pubitemid 40299793)
    • (2005) Annual Review of Medicine , vol.56 , pp. 459-474
    • Fraser, C.M.1    Rappuoli, R.2
  • 60
    • 23944506044 scopus 로고    scopus 로고
    • Mobile genetic elements: The agents of open source evolution
    • DOI 10.1038/nrmicro1235
    • Frost LS, Leplae R, Summers AO, Toussaint A. 2005. Mobile genetic elements: the agents of open source evolution. Nat. Rev. Microbiol. 3:722-32 (Pubitemid 41195088)
    • (2005) Nature Reviews Microbiology , vol.3 , Issue.9 , pp. 722-732
    • Frost, L.S.1    Leplae, R.2    Summers, A.O.3    Toussaint, A.4
  • 64
    • 9044222878 scopus 로고    scopus 로고
    • HSP60 gene sequences as universal targets for microbial species identification: Studies with coagulase-negative staphylococci
    • Goh SH, Potter S,Wood JO, Hemmingsen SM, Reynolds RP, Chow AW. 1996. HSP60 gene sequences as universal targets for microbial species identification: studies with coagulase-negative staphylococci. J. Clin. Microbiol. 34:818-23 (Pubitemid 26091489)
    • (1996) Journal of Clinical Microbiology , vol.34 , Issue.4 , pp. 818-823
    • Gob, S.H.1    Potter, S.2    Wood, J.O.3    Hemmingsen, S.M.4    Reynolds, R.P.5    Chow, A.W.6
  • 65
    • 0034006265 scopus 로고    scopus 로고
    • Genome-sequence-based fluorescent amplified-fragment length polymorphism analysis of Mycobacterium tuberculosis
    • Goulding JN, Stanley J, Saunders N, Arnold C. 2000. Genome-sequence-based fluorescent amplifiedfragment length polymorphism analysis of Mycobacterium tuberculosis. J. Clin. Microbiol. 38:1121-26 (Pubitemid 30140569)
    • (2000) Journal of Clinical Microbiology , vol.38 , Issue.3 , pp. 1121-1126
    • Goulding, J.N.1    Stanley, J.2    Saunders, N.3    Arnold, C.4
  • 66
    • 0033613213 scopus 로고    scopus 로고
    • Identification of Mycobacterium tuberculosis RNAs synthesized in response to phagocytosis by human macrophages by selective capture of transcribed sequences (SCOTS)
    • DOI 10.1073/pnas.96.20.11554
    • Graham JE, Clark-Curtiss JE. 1999. Identification of Mycobacterium tuberculosis RNAs synthesized in response to phagocytosis by human macrophages by selective capture of transcribed sequences (SCOTS). Proc. Natl. Acad. Sci. USA 96:11554-59 (Pubitemid 29487419)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.20 , pp. 11554-11559
    • Graham, J.E.1    Clark-Curtiss, J.E.2
  • 67
    • 77949493112 scopus 로고    scopus 로고
    • High throughput sequencing and proteomics to identify immunogenic proteins of a new pathogen: The dirty genome approach
    • Greub G, Kebbi-Beghdadi C, Bertelli C, Collyn F, Riederer BM, et al. 2009. High throughput sequencing and proteomics to identify immunogenic proteins of a new pathogen: the dirty genome approach. PLoS One 4:e8423
    • (2009) PLoS One , vol.4
    • Greub, G.1    Kebbi-Beghdadi, C.2    Bertelli, C.3    Collyn, F.4    Riederer, B.M.5
  • 68
    • 75649084906 scopus 로고    scopus 로고
    • Evolution of MRSA during hospital transmission and intercontinental spread
    • Harris SR, Feil EJ, Holden MT, Quail MA, Nickerson EK, et al. 2010. Evolution of MRSA during hospital transmission and intercontinental spread. Science 327:469-74
    • (2010) Science , vol.327 , pp. 469-74
    • Harris, S.R.1    Feil, E.J.2    Holden, M.T.3    Quail, M.A.4    Nickerson, E.K.5
  • 71
    • 0036716927 scopus 로고    scopus 로고
    • Glycogen metabolism loss: A common marker of parasitic behaviour in bacteriá
    • Henrissat B, Deleury E, Coutinho PM. 2002. Glycogen metabolism loss: a common marker of parasitic behaviour in bacteriá Trends Genet. 18:437-40
    • (2002) Trends Genet. , vol.18 , pp. 437-40
    • Henrissat, B.1    Deleury, E.2    Coutinho, P.M.3
  • 72
    • 0029117137 scopus 로고
    • Simultaneous identification of bacterial virulence genes by negative selection
    • Hensel M, Shea JE, Gleeson C, Jones MD, Dalton E, Holden DW. 1995. Simultaneous identification of bacterial virulence genes by negative selection. Science 269:400-3
    • (1995) Science , vol.269 , pp. 400-3
    • Hensel, M.1    Shea, J.E.2    Gleeson, C.3    Jones, M.D.4    Dalton, E.5    Holden, D.W.6
  • 74
    • 52949115612 scopus 로고    scopus 로고
    • Microbiology: Metagenomics
    • Hugenholtz P, Tyson GW. 2008. Microbiology: metagenomics. Nature 455:481-83
    • (2008) Nature , vol.455 , pp. 481-83
    • Hugenholtz, P.1    Tyson, G.W.2
  • 75
    • 27344443267 scopus 로고    scopus 로고
    • Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization
    • DOI 10.1126/science.1116739
    • Hung DT, Shakhnovich EA, Pierson E, Mekalanos JJ. 2005. Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization. Science 310:670-74 (Pubitemid 41528158)
    • (2005) Science , vol.310 , Issue.5748 , pp. 670-674
    • Hung, D.T.1    Shakhnovich, E.A.2    Pierson, E.3    Mekalanos, J.J.4
  • 78
    • 0037079023 scopus 로고    scopus 로고
    • Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth
    • DOI 10.1038/nature01149
    • Ibarra RU, Edwards JS, Palsson BO. 2002. Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth. Nature 420:186-89 (Pubitemid 35340123)
    • (2002) Nature , vol.420 , Issue.6912 , pp. 186-189
    • Ibarra, R.U.1    Edwards, J.S.2    Palsson, B.O.3
  • 79
    • 0242593808 scopus 로고    scopus 로고
    • Characterization of the Natural Population of Bartonella henselae by Multilocus Sequence Typing
    • DOI 10.1128/JCM.41.11.5071-5079.2003
    • Iredell J, Blanckenberg D, Arvand M, Grauling S, Feil EJ, Birtles RJ. 2003. Characterization of the natural population of Bartonella henselae by multilocus sequence typing. J. Clin. Microbiol. 41:5071-79 (Pubitemid 37429918)
    • (2003) Journal of Clinical Microbiology , vol.41 , Issue.11 , pp. 5071-5079
    • Iredell, J.1    Blanckenberg, D.2    Arvand, M.3    Grauling, S.4    Feil, E.J.5    Birtles, R.J.6
  • 83
    • 0035399931 scopus 로고    scopus 로고
    • Detecting anomalous gene clusters and pathogenicity islands in diverse bacterial genomes
    • DOI 10.1016/S0966-842X(01)02079-0, PII S0966842X01020790
    • Karlin S. 2001. Detecting anomalous gene clusters and pathogenicity islands in diverse bacterial genomes. Trends Microbiol. 9:335-43 (Pubitemid 32575278)
    • (2001) Trends in Microbiology , vol.9 , Issue.7 , pp. 335-343
    • Karlin, S.1
  • 84
    • 65549152272 scopus 로고    scopus 로고
    • Differential gene repertoire in Mycobacterium ulcerans identifies candidate genes for patho-adaptation
    • Käser M, Pluschke G. 2008. Differential gene repertoire in Mycobacterium ulcerans identifies candidate genes for patho-adaptation. PLoS Negl. Trop. Dis. 2:e353
    • (2008) PLoS Negl. Trop. Dis. , vol.2
    • Käser, M.1    Pluschke, G.2
  • 85
    • 43549087573 scopus 로고    scopus 로고
    • Developing antibacterial vaccines in genomics and proteomics era
    • DOI 10.1111/j.1365-3083.2008.02107.x
    • Kaushik DK, Sehgal D. 2008. Developing antibacterial vaccines in genomics and proteomics era. Scand. J. Immunol. 67:544-52 (Pubitemid 351677415)
    • (2008) Scandinavian Journal of Immunology , vol.67 , Issue.6 , pp. 544-552
    • Kaushik, D.K.1    Sehgal, D.2
  • 87
    • 28944435503 scopus 로고    scopus 로고
    • Leptospirosis vaccines: Past, present, and future
    • Koizumi N, Watanabe H. 2005. Leptospirosis vaccines: past, present, and future. J. Postgrad. Med. 51:210-14 (Pubitemid 41782218)
    • (2005) Journal of Postgraduate Medicine , vol.51 , Issue.3 , pp. 210-214
    • Koizumi, N.1    Watanabe, H.2
  • 88
    • 57149085868 scopus 로고    scopus 로고
    • Genomics of bacteria and archaea: The emerging dynamic view of the prokaryotic world
    • Koonin EV, Wolf YI. 2008. Genomics of bacteria and archaea: the emerging dynamic view of the prokaryotic world. Nucleic Acids Res. 36:6688-719
    • (2008) Nucleic Acids Res. , vol.36 , pp. 6688-719
    • Koonin, E.V.1    Wolf, Y.I.2
  • 89
    • 33745082767 scopus 로고    scopus 로고
    • Identification of candidate antigen in Whipple's disease using a serological proteomic approach
    • DOI 10.1002/pmic.200500171
    • Kowalczewska M, Fenollar F, Lafitte D, RaoultD. 2006. Identification of candidate antigen inWhipple's disease using a serological proteomic approach. Proteomics. 6:3294-305 (Pubitemid 43886147)
    • (2006) Proteomics , vol.6 , Issue.11 , pp. 3294-3305
    • Kowalczewska, M.1    Fenollar, F.2    Lafitte, D.3    Raoult, D.4
  • 93
    • 0037436090 scopus 로고    scopus 로고
    • Genomics-based design of defined growth media for the plant pathogen Xylella fastidiosa
    • DOI 10.1016/S0378-1097(02)01189-8
    • Lemos EG, Alves LM, Campanharo JC. 2003. Genomics-based design of defined growth media for the plant pathogen Xylella fastidiosa. FEMS Microbiol. Lett. 219:39-45 (Pubitemid 36194776)
    • (2003) FEMS Microbiology Letters , vol.219 , Issue.1 , pp. 39-45
    • Lemos, E.G.D.M.1    Alves, L.M.C.2    Campanharo, J.C.3
  • 94
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • DOI 10.1038/4441022a, PII 4441022A
    • Ley RE, Turnbaugh PJ, Klein S, Gordon JI. 2006. Microbial ecology: human gut microbes associated with obesity. Nature 444:1022-23 (Pubitemid 46018512)
    • (2006) Nature , vol.444 , Issue.7122 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 95
    • 0034513621 scopus 로고    scopus 로고
    • Assessment of bacterial pathogenesis by analysis of gene expression in the host
    • DOI 10.1146/annurev.genet.34.1.139
    • Mahan MJ, Heithoff DM, Sinsheimer RL, Low DA. 2000. Assessment of bacterial pathogenesis by analysis of gene expression in the host. Annu. Rev. Genet. 34:139-64 (Pubitemid 32065918)
    • (2000) Annual Review of Genetics , vol.34 , pp. 139-164
    • Mahan, M.J.1    Heithoff, D.M.2    Sinsheimer, R.L.3    Low, D.A.4
  • 96
    • 0027497926 scopus 로고
    • Selection of bacterial virulence genes that are specifically induced in host tissues
    • Mahan MJ, Slauch JM, Mekalanos JJ. 1993. Selection of bacterial virulence genes that are specifically induced in host tissues. Science 259:686-88 (Pubitemid 23066292)
    • (1993) Science , vol.259 , Issue.5095 , pp. 686-688
    • Mahan, M.J.1    Slauch, J.M.2    Mekalanos, J.J.3
  • 101
    • 0037997057 scopus 로고    scopus 로고
    • Molecular evaluation of antibiotic susceptibility: Tropheryma whipplei paradigm
    • DOI 10.1128/AAC.47.5.1658-1664.2003
    • Masselot F, Boulos A, Maurin M, Rolain JM, Raoult D. 2003. Molecular evaluation of antibiotic susceptibility: Tropheryma whipplei paradigm. Antimicrob. Agents Chemother. 47:1658-64 (Pubitemid 36548552)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.5 , pp. 1658-1664
    • Masselot, F.1    Boulos, A.2    Maurin, M.3    Rolain, J.M.4    Raoult, D.5
  • 105
    • 70449112966 scopus 로고    scopus 로고
    • Basic concepts of microarrays and potential applications in clinical microbiology
    • Miller MB, Tang YW. 2009. Basic concepts of microarrays and potential applications in clinical microbiology. Clin. Microbiol. Rev. 22:611-33
    • (2009) Clin. Microbiol. Rev. , vol.22 , pp. 611-33
    • Miller, M.B.1    Tang, Y.W.2
  • 106
    • 77952692819 scopus 로고    scopus 로고
    • Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli
    • Moriel DG, Bertoldi I, Spagnuolo A, Marchi S, Rosini R, et al. 2010. Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli. Proc. Natl. Acad. Sci. USA 107:9072-77
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 9072-77
    • Moriel, D.G.1    Bertoldi, I.2    Spagnuolo, A.3    Marchi, S.4    Rosini, R.5
  • 108
    • 34249042613 scopus 로고    scopus 로고
    • The pan-genome: Towards a knowledge-based discovery of novel targets for vaccines and antibacterials
    • DOI 10.1016/j.drudis.2007.04.008, PII S1359644607001778
    • Muzzi A, Masignani V, Rappuoli R. 2007. The pan-genome: towards a knowledge-based discovery of novel targets for vaccines and antibacterials. Drug Discov. Today 12:429-39 (Pubitemid 46783689)
    • (2007) Drug Discovery Today , vol.12 , Issue.11-12 , pp. 429-439
    • Muzzi, A.1    Masignani, V.2    Rappuoli, R.3
  • 109
    • 17644371042 scopus 로고    scopus 로고
    • Small-molecule inhibitors specifically targeting type III secretion
    • DOI 10.1128/IAI.73.5.3104-3114.2005
    • Nordfelth R, Kauppi AM, Norberg HA, Wolf-Watz H, Elofsson M. 2005. Small-molecule inhibitors specifically targeting type III secretion. Infect. Immun. 73:3104-14 (Pubitemid 40570380)
    • (2005) Infection and Immunity , vol.73 , Issue.5 , pp. 3104-3114
    • Nordfelth, R.1    Kauppi, A.M.2    Norberg, H.A.3    Wolf-Watz, H.4    Elofsson, M.5
  • 111
    • 33646910500 scopus 로고    scopus 로고
    • Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens
    • Ogata H, La Scola B, Audic S, Renesto P, Blanc G, et al. 2006. Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens. PLoS Genet. 2:e76
    • (2006) PLoS Genet. , vol.2
    • Ogata, H.1    La Scola, B.2    Audic, S.3    Renesto, P.4    Blanc, G.5
  • 112
    • 23944507559 scopus 로고    scopus 로고
    • The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite
    • Ogata H, Renesto P, Audic S, Robert C, Blanc G, et al. 2005. The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite. PLoS. Biol. 3:e248
    • (2005) PLoS. Biol. , vol.3
    • Ogata, H.1    Renesto, P.2    Audic, S.3    Robert, C.4    Blanc, G.5
  • 114
    • 77957769655 scopus 로고    scopus 로고
    • High-throughput sequencing and clinical microbiology: Progress, opportunities and challenges
    • Pallen MJ, Loman NJ, Penn CW. 2010. High-throughput sequencing and clinical microbiology: progress, opportunities and challenges. Curr. Opin. Microbiol. 13:625-31
    • (2010) Curr. Opin. Microbiol. , vol.13 , pp. 625-31
    • Pallen, M.J.1    Loman, N.J.2    Penn, C.W.3
  • 117
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: Confronting the challenges of antibacterial discovery
    • DOI 10.1038/nrd2201, PII NRD2201
    • Payne DJ,GwynnMN, Holmes DJ, PomplianoDL. 2007. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat. Rev. Drug. Discov. 6:29-40 (Pubitemid 46020284)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.1 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3    Pompliano, D.L.4
  • 119
    • 74549202659 scopus 로고    scopus 로고
    • Genome-wide dissection of globally emergent multi-drug resistant serotype 19A Streptococcus pneumoniae
    • Pillai DR, Shahinas D, Buzina A, Pollock RA, Lau R, et al. 2009. Genome-wide dissection of globally emergent multi-drug resistant serotype 19A Streptococcus pneumoniae. BMC Genomics 10:642
    • (2009) BMC Genomics , vol.10 , pp. 642
    • Pillai, D.R.1    Shahinas, D.2    Buzina, A.3    Pollock, R.A.4    Lau, R.5
  • 120
    • 0034629284 scopus 로고    scopus 로고
    • Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing
    • Pizza M, Scarlato V,Masignani V, Giuliani MM, Arico B, et al. 2000. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science 287:1816-20
    • (2000) Science , vol.287 , pp. 1816-20
    • Pizza, M.1    Scarlato, V.2    Masignani, V.3    Giuliani, M.M.4    Arico, B.5
  • 121
    • 0037050288 scopus 로고    scopus 로고
    • Identification and molecular characterisation of CmeB, a Campylobacter jejuni multidrug efflux pump
    • DOI 10.1016/S0378-1097(01)00532-8, PII S0378109701005328
    • Pumbwe L, Piddock LJ. 2002. Identification and molecular characterisation of CmeB, a Campylobacter jejuni multidrug efflux pump. FEMS Microbiol. Lett. 206:185-89 (Pubitemid 34117617)
    • (2002) FEMS Microbiology Letters , vol.206 , Issue.2 , pp. 185-189
    • Pumbwe, L.1    Piddock, L.J.V.2
  • 124
    • 0242523909 scopus 로고    scopus 로고
    • The uncultured microbial majority
    • DOI 10.1146/annurev.micro.57.030502.090759
    • Rappe MS, Giovannoni SJ. 2003. The uncultured microbial majority. Annu. Rev. Microbiol. 57:369-94 (Pubitemid 37392948)
    • (2003) Annual Review of Microbiology , vol.57 , pp. 369-394
    • Rappe, M.S.1    Giovannoni, S.J.2
  • 125
    • 0035925596 scopus 로고    scopus 로고
    • Reverse vaccinology, a genome-based approach to vaccine development
    • DOI 10.1016/S0264-410X(00)00554-5, PII S0264410X00005545
    • Rappuoli R. 2001. Reverse vaccinology, a genome-based approach to vaccine development. Vaccine 19:2688-91 (Pubitemid 32234290)
    • (2001) Vaccine , vol.19 , Issue.17-19 , pp. 2688-2691
    • Rappuoli, R.1
  • 127
    • 0025258967 scopus 로고
    • The agent of bacillary angiomatosis: An approach to the identification of uncultured pathogens
    • Relman DA, Loutit JS, Schmidt TM, Falkow S, Tompkins LS. 1990. The agent of bacillary angiomatosis: an approach to the identification of uncultured pathogens. N. Engl. J. Med. 323:1573-80
    • (1990) N. Engl. J. Med. , vol.323 , pp. 1573-80
    • Relman, D.A.1    Loutit, J.S.2    Schmidt, T.M.3    Falkow, S.4    Tompkins, L.S.5
  • 128
    • 0043237947 scopus 로고    scopus 로고
    • Genome-based design of a cell-free culture medium for Tropheryma whipplei
    • DOI 10.1016/S0140-6736(03)14071-8
    • Renesto P, Crapoulet N, OgataH, La Scola B, VestrisG, et al. 2003. Genome-based design of a cell-free culture medium for Tropheryma whipplei. Lancet 362:447-49 (Pubitemid 36999709)
    • (2003) Lancet , vol.362 , Issue.9382 , pp. 447-449
    • Renesto, P.1    Crapoulet, N.2    Ogata, H.3    La Scola, B.4    Vestris, G.5    Claverie, J.-M.6    Raoult, D.7
  • 129
    • 0242468462 scopus 로고    scopus 로고
    • Identification and Characterization of a Phospholipase D-Superfamily Gene in Rickettsiae
    • DOI 10.1086/379080
    • Renesto P,Dehoux P, Gouin E,Touqui L, Cossart P, RaoultD. 2003. Identification and characterization of a phospholipase D-superfamily gene in rickettsiae. J. Infect. Dis. 188:1276-83 (Pubitemid 37433697)
    • (2003) Journal of Infectious Diseases , vol.188 , Issue.9 , pp. 1276-1283
    • Renesto, P.1    Dehoux, P.2    Gouin, E.3    Touqui, L.4    Cossart, P.5    Raoult, D.6
  • 130
    • 33747363728 scopus 로고    scopus 로고
    • Identification of two putative rickettsial adhesins by proteomic analysis
    • Renesto P, Samson L, Ogata H, Azza S, Fourquet P, et al. 2006. Identification of two putative rickettsial adhesins by proteomic analysis. Res. Microbiol. 157:605-12
    • (2006) Res. Microbiol. , vol.157 , pp. 605-12
    • Renesto, P.1    Samson, L.2    Ogata, H.3    Azza, S.4    Fourquet, P.5
  • 132
    • 9244239747 scopus 로고    scopus 로고
    • Global transposon mutagenesis and essential gene analysis of Helicobacter pylori
    • DOI 10.1128/JB.186.23.7926-7935.2004
    • Salama NR, Shepherd B, Falkow S. 2004. Global transposon mutagenesis and essential gene analysis of Helicobacter pylori. J. Bacteriol. 186:7926-35 (Pubitemid 39552503)
    • (2004) Journal of Bacteriology , vol.186 , Issue.23 , pp. 7926-7935
    • Salama, N.R.1    Shepherd, B.2    Falkow, S.3
  • 133
    • 0034060956 scopus 로고    scopus 로고
    • Hepatitis C: An update on the silent epidemic
    • DOI 10.1097/00004836-200003000-00005
    • Sarbah SA, Younossi ZM. 2000. Hepatitis C: an update on the silent epidemic. J. Clin. Gastroenterol. 30:125-43 (Pubitemid 30148441)
    • (2000) Journal of Clinical Gastroenterology , vol.30 , Issue.2 , pp. 125-143
    • Sarbah, S.A.1    Younossi, Z.M.2
  • 136
    • 0034615788 scopus 로고    scopus 로고
    • Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysis
    • Schilling CH, Palsson BO. 2000. Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysis. J. Theor. Biol. 203:249-83
    • (2000) J. Theor. Biol. , vol.203 , pp. 249-83
    • Schilling, C.H.1    Palsson, B.O.2
  • 137
    • 33845894155 scopus 로고    scopus 로고
    • Multi-targeting by monotherapeutic antibacterials
    • DOI 10.1038/nrd2202, PII NRD2202
    • Silver LL. 2007. Multi-targeting by monotherapeutic antibacterials. Nat. Rev. Drug. Discov. 6:41-55 (Pubitemid 46020285)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.1 , pp. 41-55
    • Silver, L.L.1
  • 146
    • 0037100683 scopus 로고    scopus 로고
    • Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae
    • Thanassi JA, Hartman-Neumann SL, Dougherty TJ, Dougherty BA, Pucci MJ. 2002. Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae. Nucleic Acids Res. 30:3152-62 (Pubitemid 34846179)
    • (2002) Nucleic Acids Research , vol.30 , Issue.14 , pp. 3152-3162
    • Thanassi, J.A.1    Hartman-Neumann, S.L.2    Dougherty, T.J.3    Dougherty, B.A.4    Pucci, M.J.5
  • 147
    • 84920629237 scopus 로고    scopus 로고
    • A renaissance for the pioneering 16S rRNA gene
    • Tringe SG,Hugenholtz P. 2008. A renaissance for the pioneering 16S rRNA gene. Curr. Opin.Microbiol. 11:442-46
    • (2008) Curr. Opin.Microbiol. , vol.11 , pp. 442-46
    • Tringe, S.G.1    Hugenholtz, P.2
  • 148
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • DOI 10.1038/nature05414, PII NATURE05414
    • Turnbaugh PJ, Ley RE,Mahowald MA,Magrini V, Mardis ER, Gordon JI. 2006. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444:1027-31 (Pubitemid 46018515)
    • (2006) Nature , vol.444 , Issue.7122 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 149
    • 23944517743 scopus 로고    scopus 로고
    • Cultivating the uncultivated: A community genomics perspective
    • DOI 10.1016/j.tim.2005.07.003, PII S0966842X05001897
    • Tyson GW, Banfield JF. 2005. Cultivating the uncultivated: a community genomics perspective. Trends Microbiol. 13:411-15 (Pubitemid 41207174)
    • (2005) Trends in Microbiology , vol.13 , Issue.9 , pp. 411-415
    • Tyson, G.W.1    Banfield, J.F.2
  • 151
    • 26844447711 scopus 로고    scopus 로고
    • Genome-directed isolation of the key nitrogen fixer Leptospirillum ferrodiazotrophum sp. nov. from an acidophilic microbial community
    • DOI 10.1128/AEM.71.10.6319-6324.2005
    • Tyson GW, Lo I, Baker BJ, Allen EE, Hugenholtz P, Banfield JF. 2005. Genome-directed isolation of the key nitrogen fixer Leptospirillum ferrodiazotrophum sp. nov. from an acidophilic microbial community. Appl. Environ. Microbiol. 71:6319-24 (Pubitemid 41456932)
    • (2005) Applied and Environmental Microbiology , vol.71 , Issue.10 , pp. 6319-6324
    • Tyson, G.W.1    Lo, I.2    Baker, B.J.3    Allen, E.E.4    Hugenholtz, P.5    Banfield, J.F.6
  • 152
    • 0030866940 scopus 로고    scopus 로고
    • Fluorescence-based isolation of bacterial genes expressed within host cells
    • DOI 10.1126/science.277.5334.2007
    • Valdivia RH, Falkow S. 1997. Fluorescence-based isolation of bacterial genes expressed within host cells. Science 277:2007-11 (Pubitemid 27449146)
    • (1997) Science , vol.277 , Issue.5334 , pp. 2007-2011
    • Valdivia, R.H.1    Falkow, S.2
  • 153
    • 77950649022 scopus 로고    scopus 로고
    • Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island
    • van Schaik W, Top J, Riley DR, Boekhorst J, Vrijenhoek JE, et al. 2010. Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island. BMC Genomics 11:239
    • (2010) BMC Genomics , vol.11 , pp. 239
    • Van Schaik, W.1    Top, J.2    Riley, D.R.3    Boekhorst, J.4    Vrijenhoek, J.E.5
  • 154
    • 39149099198 scopus 로고    scopus 로고
    • Single-cell genomics
    • DOI 10.1038/nrmicro1862, PII NRMICRO1862
    • Walker A, Parkhill J. 2008. Single-cell genomics. Nat. Rev. Microbiol. 6:176-77 (Pubitemid 351256312)
    • (2008) Nature Reviews Microbiology , vol.6 , Issue.3 , pp. 176-177
    • Walker, A.1    Parkhill, J.2
  • 158
    • 77954761569 scopus 로고    scopus 로고
    • Integrative and conjugative elements: Mosaic mobile genetic elements enabling dynamic lateral gene flow
    • Wozniak RA,Waldor MK. 2010. Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow. Nat. Rev. Microbiol. 8:552-63
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 552-63
    • Wozniak, R.A.1    Waldor, M.K.2
  • 159
    • 33847151750 scopus 로고    scopus 로고
    • The antibiotic resistome: The nexus of chemical and genetic diversity
    • DOI 10.1038/nrmicro1614, PII NRMICRO1614
    • Wright GD. 2007. The antibiotic resistome: the nexus of chemical and genetic diversity. Nat. Rev. Microbiol. 5:175-86 (Pubitemid 46291277)
    • (2007) Nature Reviews Microbiology , vol.5 , Issue.3 , pp. 175-186
    • Wright, G.D.1
  • 160
    • 72949101201 scopus 로고    scopus 로고
    • A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea
    • Wu D, Hugenholtz P, Mavromatis K, Pukall R, Dalin E, et al. 2009. A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea. Nature 462:1056-60
    • (2009) Nature , vol.462 , pp. 1056-60
    • Wu, D.1    Hugenholtz, P.2    Mavromatis, K.3    Pukall, R.4    Dalin, E.5
  • 161
    • 10644242777 scopus 로고    scopus 로고
    • Development and evaluation of microarray-based whole-genome hybridization for detection of microorganisms within the context of environmental applications
    • DOI 10.1021/es049508i
    • Wu L, Thompson DK, Liu X, Fields MW, Bagwell CE, et al. 2004. Development and evaluation of microarray-based whole-genome hybridization for detection of microorganisms within the context of environmental applications. Environ. Sci. Technol. 38:6775-82 (Pubitemid 39658116)
    • (2004) Environmental Science and Technology , vol.38 , Issue.24 , pp. 6775-6782
    • Wu, L.1    Thompson, D.K.2    Liu, X.3    Fields, M.W.4    Bagwell, C.E.5    Tiedje, J.M.6    Zhou, J.7
  • 162
    • 27744500887 scopus 로고    scopus 로고
    • Selection of protective epitopes for Brucella melitensis by DNA vaccination
    • DOI 10.1128/IAI.73.11.7297-7303.2005
    • Yang X, Hudson M, Walters N, Bargatze RF, Pascual DW. 2005. Selection of protective epitopes for Brucella melitensis by DNA vaccination. Infect. Immun. 73:7297-303 (Pubitemid 41587629)
    • (2005) Infection and Immunity , vol.73 , Issue.11 , pp. 7297-7303
    • Yang, X.1    Hudson, M.2    Walters, N.3    Bargatze, R.F.4    Pascual, D.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.