From microbial genome sequence to applications

Research in Microbiology

Volumn 151, Issue 2, 2000, Pages 151-158

  Weinstock, George M ^a   Smajs, David ^a   Hardham, John ^a   Norris, Steven J ^b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

Diagnostics; Syphilis; Vaccine

Indexed keywords

BACTERIAL PROTEIN; GENE PRODUCT; HISTIDINE; HYBRID PROTEIN; TPRF PROTEIN; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; BACTERIAL GENE; CONTROLLED STUDY; DRUG RESEARCH; ESCHERICHIA COLI; GENE EXPRESSION; GENE SEQUENCE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RABBIT; REVIEW; SERODIAGNOSIS; SYPHILIS; TREPONEMA PALLIDUM; VACCINE PRODUCTION;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; ORYCTOLAGUS CUNICULUS; TREPONEMA PALLIDUM;

EID: 0034040756     PISSN: 09232508     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2508(00)00115-7     Document Type: Review

References (11)

1. Akerley B.J., Rubin E.J., Camilli A., Lampe D.J., Robertson H.M., Mekalanos J.J. Systematic identification of essential genes by in vitro mariner mutagenesis. Proc. Natl. Acad. Sci. USA. 95:1998;8927-8932.
2. Egli C., Leung W.K., Muller K.H., Hancock R.E., McBride B.C. Pore-forming properties of the major 53-kilodalton surface antigen from the outer sheath of Treponema denticola. Infect. Immun. 61:1993;1694-1699.
3. Fenno J.C., Muller K.H., McBride B.C. Sequence analysis, expression, and binding activity of recombinant major outer sheath protein (Msp) of Treponema denticola. J. Bacteriol. 178:1996;2489-2497.
4. Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R., Gwinn M., Hickey E.K., Clayton R., Ketchum K.A., Sodergren E., Hardham J.M., Mc Leod M.P., Salzberg S., Peterson J., Khalak H., Richardson D., Howell J.K., Chidambaram M., Utterback T., McDonald L., Artiach P., Bowman C., Cotton M.D., Venter J.C. Complete genome sequence of Treponema pallidum, the syphilis spirochete. Science. 281:1998;375-388.
5. Hensel M., Shea J.E., Gleeson C., Jones M.D., Dalton E., Holden D.W. Simultaneous identification of bacterial virulence genes by negative selection. Science. 269:1995;400-403.
6. Mathers D.A., Leung W.K., Fenno J.C., Hong Y., McBride B.C. The major surface protein complex of Treponema denticola depolarizes and induces ion channels in HeLa cell membranes. Infect. Immun. 64:1996;2904-2910.
7. Palzkill T., Huang W., Weinstock G.M. Mapping protein-ligand interactions using whole genome phage display libraries. Gene. 221:1998;79-83.
8. Schaudinn F. Korrespondenzen. Deut. Med. Wochenschr. 31:1905;1728.
9. Schaudinn F., Hoffman E. Vorlaufiger bericht uber das vorkommen fur spirochaeten in syphilitischen krankheitsprodukten und be papillomen. Arb. Gesundh. Amt. Berlin. 22:1905;528-534.
10. Umemoto T., Nakatani Y., Nakamura Y., Namikawa I. Fibronectin-binding proteins of a human oral spirochete Treponema denticola. Microbiol. Immunol. 37:1993;75-78.
11. Weinstock G.M., Hardham J.M., McLeod M.P., Sodergren E.J., Norris S.J. The genome of Treponema pallidum: new light on the agent of syphilis. FEMS Microbiol. Rev. 22:1998;323-332.