Genome-wide dissection of globally emergent multi-drug resistant serotype 19A Streptococcus pneumoniae

BMC Genomics

Volumn 10, Issue , 2009, Pages

  Pillai, Dylan R ^a,b,c   Shahinas, Dea ^a   Buzina, Alla ^b   Pollock, Remy A ^b   Lau, Rachel ^b   Khairnar, Krishna ^b   Wong, Andrew ^b   Farrell, David J ^a,b   Green, Karen ^c   McGeer, Allison ^a,c   Low, Donald E ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b PUBLIC HEALTH ONTARIO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIBIOTIC AGENT; BACTERIAL DNA; CEFTRIAXONE; CIPROFLOXACIN; ERYTHROMYCIN; PENICILLIN BINDING PROTEIN 2A; PENICILLIN BINDING PROTEIN 2B; PENICILLIN BINDING PROTEIN 2X; PENICILLIN G; VIRULENCE FACTOR; ANTIINFECTIVE AGENT; HEPTAVALENT PNEUMOCOCCAL CONJUGATE VACCINE; PNEUMOCOCCUS VACCINE;

ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATION; CANADA; CONTROLLED STUDY; DNA SEQUENCE; GENE LOCUS; GENETIC CONSERVATION; GENETIC RECOMBINATION; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; MULTILOCUS SEQUENCE TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; SEQUENCE ANALYSIS; SEROTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; STREPTOCOCCUS PNEUMONIAE; BACTERIAL GENOME; BIOLOGY; CLASSIFICATION; COMPARATIVE GENOMIC HYBRIDIZATION; DRUG EFFECT; GENETICS; MICROBIOLOGICAL EXAMINATION; SEROTYPING;

STREPTOCOCCUS PNEUMONIAE;

ANTI-BACTERIAL AGENTS; CANADA; COMPARATIVE GENOMIC HYBRIDIZATION; COMPUTATIONAL BIOLOGY; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENOME, BACTERIAL; MICROBIAL SENSITIVITY TESTS; PNEUMOCOCCAL VACCINES; SEQUENCE ANALYSIS, DNA; SEROTYPING; STREPTOCOCCUS PNEUMONIAE;

EID: 74549202659     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-10-642     Document Type: Article

References (39)

1. Dagan R, Klugman KP. Impact of conjugate pneumococcal vaccines on antibiotic resistance. Lancet Infect Dis 2008, 8:785-795. 10.1016/S1473-3099(08)70281-0, 19022193.
2. Song JH, Baek JY, Cheong HS, Chung DR, Peck KR, Ko KS. Changes of serotype and genotype in Streptococcus pneumoniae isolates from a Korean hospital in 2007. Diagn Microbiol Infect Dis 2009, 63:271-278. 10.1016/j.diagmicrobio.2008.11.015, 19179034.
3. Fenoll A, Granizo JJ, Aguilar L, Gimenez MJ, Aragoneses-Fenoll L, Hanquet G, Casal J, Tarrago D. Temporal trends of invasive Streptococcus pneumoniae serotypes and antimicrobial resistance patterns in Spain from 1979 to 2007. J Clin Microbiol 2009, 47:1012-1020. 10.1128/JCM.01454-08, 2668361, 19225097.
4. Mahjoub-Messai F, Doit C, Koeck JL, Billard T, Evrard B, Bidet P, Hubans C, Raymond J, Levy C, Cohen R, Bingen E. Population snapshot of Streptococcus pneumoniae serotype 19A isolates before and after introduction of seven-valent pneumococcal Vaccination for French children. J Clin Microbiol 2009, 47:837-840. 10.1128/JCM.01547-08, 2650921, 19109482.
5. Ciccotelli WA, Poutanen SM, Alqahtani M, Morris SK, Cox P, Low DE, Pillai DR, Opavsky MA. A new twist on an old problem. A case of pediatric meningitis caused by multidrug-resistant Streptococcus pneumoniae serotype 19a. Pediatr Infect Dis J 2009, 28:74-75.
6. Jacobs MR, Good CE, Bajaksouzian S, Windau AR. Emergence of Streptococcus pneumoniae serotypes 19A, 6C, and 22F and serogroup 15 in Cleveland, Ohio, in relation to introduction of the protein-conjugated pneumococcal vaccine. Clin Infect Dis 2008, 47:1388-1395. 10.1086/592972, 18959493.
7. Amrine-Madsen H, Van EJ, Mera RM, Miller LA, Poupard JA, Thomas ES, Halsey WS, Becker JA, O'Hara FP. Temporal and spatial distribution of clonal complexes of Streptococcus pneumoniae isolates resistant to multiple classes of antibiotics in Belgium, 1997 to 2004. Antimicrob Agents Chemother 2008, 52:3216-3220. 10.1128/AAC.00358-08, 2533454, 18573928.
8. Pelton SI, Huot H, Finkelstein JA, Bishop CJ, Hsu KK, Kellenberg J, Huang SS, Goldstein R, Hanage WP. Emergence of 19A as virulent and multidrug resistant Pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine. Pediatr Infect Dis J 2007, 26:468-472. 10.1097/INF.0b013e31803df9ca, 17529860.
9. Dagan R. Impact of pneumococcal conjugate vaccine on infections caused by antibiotic-resistant Streptococcus pneumoniae. Clin Microbiol Infect 2009, 15(Suppl 3):16-20. 10.1111/j.1469-0691.2009.02726.x, 19366365.
10. Moore MR, Gertz RE, Woodbury RL, Barkocy-Gallagher GA, Schaffner W, Lexau C, Gershman K, Reingold A, Farley M, Harrison LH, Hadler JL, Bennett NM, Thomas AR, McGee L, Pilishvili T, Brueggemann AB, Whitney CG, Jorgensen JH, Beall B. Population snapshot of emergent Streptococcus pneumoniae serotype 19A in the United States, 2005. J Infect Dis 2008, 197:1016-1027. 10.1086/528996, 18419539.
11. Bae S, Lee K. Distribution of capsular serotypes and macrolide resistance mechanisms among macrolide-resistant Streptococcus pneumoniae isolates in Korea. Diagn Microbiol Infect Dis 2009, 63:213-216. 10.1016/j.diagmicrobio.2008.10.002, 19097840.
12. Brueggemann AB, Pai R, Crook DW, Beall B. Vaccine escape recombinants emerge after pneumococcal vaccination in the United States. PLoS Pathog 2007, 3:e168. 10.1371/journal.ppat.0030168, 2077903,2077903, 18020702.
13. Pai R, Moore MR, Pilishvili T, Gertz RE, Whitney CG, Beall B. Postvaccine genetic structure of Streptococcus pneumoniae serotype 19A from children in the United States. J Infect Dis 2005, 192:1988-1995. 10.1086/498043, 16267772.
14. Choi EH, Kim SH, Eun BW, Kim SJ, Kim NH, Lee J, Lee HJ. Streptococcus pneumoniae serotype 19A in children, South Korea. Emerg Infect Dis 2008, 14:275-281. 10.3201/eid1402.070807, 2600206, 18258121.
15. Zhanel GG, Wang X, Nichol K, Nikulin A, Wierzbowski AK, Mulvey M, Hoban DJ. Molecular characterisation of Canadian paediatric multidrug-resistant Streptococcus pneumoniae from 1998-2004. Int J Antimicrob Agents 2006, 28:465-471. 10.1016/j.ijantimicag.2006.08.005, 17049211.
16. McClure CA, Ford MW, Wilson JB, Aramini JJ. Pneumococcal conjugate vaccination in Canadian infants and children younger than five years of age: Recommendations and expected benefits. Can J Infect Dis Med Microbiol 2006, 17:19-26. 2095050, 18418479.
17. Hsieh YC, Chang KY, Huang YC, Lin HC, Ho YH, Huang LM, Hsueh PR. Clonal spread of highly beta-lactam-resistant Streptococcus pneumoniae isolates in Taiwan. Antimicrob Agents Chemother 2008, 52:2266-2269. 10.1128/AAC.00046-08, 2415753, 18413298.
18. Farrell DJ, Morrissey I, Bakker S, Morris L, Buckridge S, Felmingham D. Molecular epidemiology of multiresistant Streptococcus pneumoniae with both erm(B)- and mef(A)-mediated macrolide resistance. J Clin Microbiol 2004, 42:764-768. 10.1128/JCM.42.2.764-768.2004, 344484, 14766850.
19. Grebe T, Hakenbeck R. Penicillin-binding proteins 2b and 2x of Streptococcus pneumoniae are primary resistance determinants for different classes of beta-lactam antibiotics. Antimicrob Agents Chemother 1996, 40:829-834. 163214, 8849235.
20. Jacobs MR, Good CE, Beall B, Bajaksouzian S, Windau AR, Whitney CG. Changes in serotypes and antimicrobial susceptibility of invasive Streptococcus pneumoniae strains in Cleveland: a quarter century of experience. J Clin Microbiol 2008, 46:982-990. 10.1128/JCM.02321-07, 2268364, 18234877.
21. Carbon S, Ireland A, Mungall CJ, Shu S, Marshall B, Lewis S. AmiGO: online access to ontology and annotation data. Bioinformatics 2009, 25:288-289. 10.1093/bioinformatics/btn615, 2639003, 19033274.
22. Bentley SD, Aanensen DM, Mavroidi A, Saunders D, Rabbinowitsch E, Collins M, Donohoe K, Harris D, Murphy L, Quail MA, Samuel G, Skovsted IC, Kaltoft MS, Barrell B, Reeves PR, Parkhill J, Spratt BG. Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes. PLoS Genet 2006, 2:e31. 10.1371/journal.pgen.0020031, 1391919,1391919, 16532061.
23. Morona JK, Morona R, Paton JC. Analysis of the 5' portion of the type 19A capsule locus identifies two classes of cpsC, cpsD, and cpsE genes in Streptococcus pneumoniae. J Bacteriol 1999, 181:3599-3605. 93832, 10348877.
24. Haas W, Sublett J, Kaushal D, Tuomanen EI. Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance. J Bacteriol 2004, 186:8463-8471. 10.1128/JB.186.24.8463-8471.2004, 532416, 15576796.
25. Pichichero ME, Casey JR. Emergence of a multiresistant serotype 19A pneumococcal strain not included in the 7-valent conjugate vaccine as an otopathogen in children. JAMA 2007, 298:1772-1778. 10.1001/jama.298.15.1772, 17940232.
26. Siira L, Rantala M, Jalava J, Hakanen AJ, Huovinen P, Kaijalainen T, Lyytikainen O, Virolainen A. Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. Antimicrob Agents Chemother 2009, 53:2066-2073. 10.1128/AAC.01464-08, 2681517, 19273677.
27. Richter SS, Heilmann KP, Dohrn CL, Riahi F, Beekmann SE, Doern GV. Changing epidemiology of antimicrobial-resistant Streptococcus pneumoniae in the United States, 2004-2005. Clin Infect Dis 2009, 48:e23-e33. 10.1086/595857, 19115971.
28. Mavroidi A, Paraskakis I, Pangalis A, Kirikou E, Charisiadou A, Athanasiou T, Tassios PT, Tzouvelekis LS. Spread of the Streptococcus pneumoniae Taiwan19F-14 clone among children in Greece. Clin Microbiol Infect 2007, 13:1213-1216. 10.1111/j.1469-0691.2007.01837.x, 17944968.
29. Zangwill KM, Greenberg DP, Chiu CY, Mendelman P, Wong VK, Chang SJ, Partridge S, Ward JI. Safety and immunogenicity of a heptavalent pneumococcal conjugate vaccine in infants. Vaccine 2003, 21:1894-1900. 10.1016/S0264-410X(03)00013-6, 12706674.
30. Brugger SD, Hathaway LJ, Muhlemann K. Streptococcus pneumoniae strain co-colonization in the nasopharynx. J Clin Microbiol 2009, 47:1750-6. 10.1128/JCM.01877-08, 2691125, 19386843.
31. Temime L, Boelle PY, Opatowski L, Guillemot D. Impact of capsular switch on invasive pneumococcal disease incidence in a vaccinated population. PLoS One 2008, 3:e3244. 10.1371/journal.pone.0003244, 2531230, 18802466.
32. Dillard JP, Caimano M, Kelly T, Yother J. Capsules and cassettes: genetic organization of the capsule locus of Streptococcus pneumoniae. Dev Biol Stand 1995, 85:261-265.
33. Chen DK, McGeer A, de Azavedo JC, Low DE. Decreased susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada. Canadian Bacterial Surveillance Network. N Engl J Med 1999, 341:233-239. 10.1056/NEJM199907223410403, 10413735.
34. Lauer BA, Reller LB. Serotypes and penicillin susceptibility of pneumococci isolated from blood. J Clin Microbiol 1980, 11:242-244. 273371, 7380999.
35. Clinical and Laboratory Standards Institute Performance standards for antimicrobial susceptibility testing: Eighteenth informational supplement. Document M100-S18 edition 2008, Wayne (PA): The Institute.
36. Enright MC, Spratt BG. A multilocus sequence typing scheme for Streptococcus pneumoniae: identification of clones associated with serious invasive disease. Microbiology 1998, 144(Pt 11):3049-3060. 10.1099/00221287-144-11-3049, 9846740.
37. Hillier LW, Marth GT, Quinlan AR, Dooling D, Fewell G, Barnett D, Fox P, Glasscock JI, Hickenbotham M, Huang W, Magrini VJ, Richt RJ, Sander SN, Stewart DA, Stromberg M, Tsung EF, Wylie T, Schedl T, Wilson RK, Mardis ER. Whole-genome sequencing and variant discovery in C. elegans. Nat Methods 2008, 5:183-188. 10.1038/nmeth.1179, 18204455.
38. Aziz RK, Bartels D, Best AA, DeJongh M, Disz T, Edwards RA, Formsma K, Gerdes S, Glass EM, Kubal M, Meyer F, Olsen GJ, Olson R, Osterman AL, Overbeek RA, McNeil LK, Paarmann D, Paczian T, Parrello B, Pusch GD, Reich C, Stevens R, Vassieva O, Vonstein V, Wilke A, Zagnitko O. The RAST Server: rapid annotations using subsystems technology. BMC Genomics 2008, 9:75. 10.1186/1471-2164-9-75, 2265698, 18261238.
39. Feil EJ, Li BC, Aanensen DM, Hanage WP, Spratt BG. eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J Bacteriol 2004, 186:1518-1530. 10.1128/JB.186.5.1518-1530.2004, 344416, 14973027.