Metagenomic analysis of the human distal gut microbiome

Science

Volumn 312, Issue 5778, 2006, Pages 1355-1359

  Gill, Steven R ^a,g   Pop, Mihai ^a,h   DeBoy, Robert T ^a   Eckburg, Paul B ^b,c,d   Turnbaugh, Peter J ^e   Samuel, Buck S ^e   Gordon, Jeffrey I ^e   Relman, David A ^b,c,d   Fraser Liggett, Claire M ^a,f   Nelson, Karen E ^a  

^a J CRAIG VENTER INSTITUTE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

^d VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^g UNIVERSITY AT BUFFALO   (United States)

^h Bldg 142   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA SEQUENCES; ENZYMES; GENETIC ENGINEERING; METABOLISM; METHANOGENS;

METHANOGENESIS; POLYMERASE; SUPERORGANISMS; XENOBIOTICS;

GENES;

AMINO ACID; DNA 16S; GLYCAN; ISOPRENOID; VITAMIN; XENOBIOTIC AGENT;

DIGESTIVE SYSTEM; GENOMICS;

ARTICLE; BASE PAIRING; DNA SEQUENCE; GENE IDENTIFICATION; HUMAN; HUMAN GENOME; INTESTINE FLORA; METABOLISM; METHANOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; BACTERIA; BIFIDOBACTERIUM; DIETARY CARBOHYDRATES; DIETARY FIBER; DNA, RIBOSOMAL; FECES; FEMALE; FERMENTATION; GENOME, BACTERIAL; GENOMICS; HUMANS; INTESTINAL MUCOSA; INTESTINES; MALE; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PHYLOGENY; RNA, RIBOSOMAL, 16S; VARIATION (GENETICS); XENOBIOTICS;

EID: 33744804299     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1124234     Document Type: Article

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35. We thank W. Nelson and I. Hance (The Institute for Genomic Research), L. Dethlefsen and E. Bik (Stanford), and D. Leip (Washington University) for their valuable assistance. This work was supported by Defense Advanced Research Projects Agency (DARPA) and the Office of Naval 1 Research grant no. ONR-N00014-02-1-1002 (S.R.G., K.E.N.), the W. M. Keck Foundation (J.I.G.), the Ellison Medical Foundation (D.A.R., J.I.G.), and NIH grants AI51259 (D.A.R.) and DK70977 (J.I.G.). B.S.S. is a recipient of a graduate research fellowship from the NSF (DGE-0202737). This whole-genome shotgun project has been deposited at the DNA Data Bank of Japan (DDBJ), European Molecular Biology. Laboratory (EMBL), and GenBank under the project accession AAQK00000000 (subject 7) and AAQL00000000 (subject 8). The version described in this paper is the first version, AAQK01000000 and AAQL01000000. All near-full-length 16S rDNA sequences were deposited at DDBJ/EMBL/GenBank under the accessions DQ325545 to DQ327606.