Increasing CREB function in the CA1 region of dorsal hippocampus rescues the spatial memory deficits in a mouse model of alzheimer's disease

Neuropsychopharmacology

Volumn 36, Issue 11, 2011, Pages 2169-2186

  Yiu, Adelaide P ^a,b   Rashid, Asim J ^a,b   Josselyn, Sheena A ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Alzheimer's disease; CREB; dendritic spines; hippocampus; Memory; watermaze

Indexed keywords

AMYLOID BETA PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA;

ALZHEIMER DISEASE; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HIPPOCAMPAL CA1 REGION; MALE; MOUSE; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; SPATIAL MEMORY;

ALZHEIMER DISEASE; ANIMALS; CA1 REGION, HIPPOCAMPAL; CRICETINAE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DISEASE MODELS, ANIMAL; HUMANS; MAZE LEARNING; MEMORY DISORDERS; MESOCRICETUS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC;

EID: 80052719486     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.107     Document Type: Article

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