β-Amyloid-(1-42) Impairs Activity-dependent cAMP-response Element-binding Protein Signaling in Neurons at Concentrations in Which Cell Survival is Not Compromised

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 17301-17306

  Tong, Liqi ^a   Thornton, Phillip L ^b   Balazs, Robert ^b   Cotman, Carl W ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CYTOLOGY; DISEASES; ENZYME INHIBITION; NEUROLOGY; SENSORY PERCEPTION;

MEMORY IMPAIRMENT;

PROTEINS;

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; BRAIN DERIVED GROWTH FACTOR; CASPASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; N METHYL DEXTRO ASPARTIC ACID; POTASSIUM CHLORIDE; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (1-42); AMYLOID BETA-PROTEIN (25-35); BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; BRAIN DERIVED NEUROTROPHIC FACTOR; CYSTEINE PROTEINASE INHIBITOR; MESSENGER RNA; N METHYLASPARTIC ACID; PEPTIDE CHLOROMETHYL KETONE; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMYLOIDOSIS; ARTICLE; CELL FUNCTION; CELL MEMBRANE DEPOLARIZATION; CELL SURVIVAL; COGNITIVE DEFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; EMBRYO; ENZYME INHIBITION; EXON; FETUS; LEARNING; MEMORY; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALIA;

AMINO ACID CHLOROMETHYL KETONES; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYSTEINE PROTEINASE INHIBITORS; EMBRYO; EXONS; GENE EXPRESSION REGULATION; N-METHYLASPARTATE; NEURONS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; POTASSIUM CHLORIDE; PROMOTER REGIONS (GENETICS); RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 0035907325     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010450200     Document Type: Article

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