Helix-mediated protein-protein interactions as targets for intervention using foldamers

Amino Acids

Volumn 41, Issue 3, 2011, Pages 743-754

  Edwards, Thomas A ^a   Wilson, Andrew J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Chemical biology; Foldamers; Helix mimetics; Protein protein interactions

Indexed keywords

ANDROGEN RECEPTOR; BETA AMINO ACID; BIM PROTEIN; CAPSID PROTEIN; FOLDAMER; GAG PROTEIN; GLYCOPROTEIN GP 41; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MOLECULAR SCAFFOLD; NOTCH RECEPTOR; OLIGOMER; PEPTIDOMIMETIC AGENT; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; PROTEIN MDM2; PROTEIN NOXA; PROTEIN NOXA B; PROTEIN P53; RE 1 SILENCING TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; APOPTOSIS; BINDING AFFINITY; CANCER INHIBITION; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; COVALENT BOND; CRYSTAL STRUCTURE; DIMERIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; MEMBRANE FUSION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; STRUCTURE ANALYSIS; VIRUS CAPSID; VIRUS ENVELOPE;

AMINO ACIDS; CAPSID; HIV ENVELOPE PROTEIN GP41; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NUCLEAR PROTEINS; PEPTIDES; PEPTIDOMIMETICS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, NOTCH; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 80052039764     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-0880-8     Document Type: Conference Paper

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