Structural insights into the degradation of Mcl-1 induced by BH3 domains

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 15, 2007, Pages 6217-6222

  Czabotar, Peter E ^a   Lee, Erinna F ^a,b   Van Delft, Mark F ^a,b   Day, Catherine L ^c   Smith, Brian J ^a   Huang, David C S ^a   Fairlie, W Douglas ^a   Hinds, Mark G ^a   Colman, Peter M ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Apoptosis; Bim; Crystallography; Noxa

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; LIGAND; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN NOXA;

APOPTOSIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CARBOXY TERMINAL SEQUENCE; CRYSTALLOGRAPHY; NITROGEN NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CRYSTALLOGRAPHY; HUMANS; MEMBRANE PROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; NEOPLASM PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS;

EID: 34547098188     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0701297104     Document Type: Article

References (49)

1. Adams JM (2003) Genes Dev 17:2481-2495.
2. Muchmore SW, Sattler M, Liang H, Meadows RP, Harlan JE, Yoon HS, Nettesheim D, Chang BS, Thompson CB, Wong S, et al. (1996) Nature 381:335-341.
3. Petros AM, Medek A, Nettesheim DG, Kim DH, Yoon HS, Swift K, Matayoshi ED, Oltersdorf T, Fesik SW (2001) Proc Natl Acad Sci USA 98:3012-3017.
4. Hinds MG, Lackmann M, Skea GL, Harrison PJ, Huang DCS, Day CL (2003) EMBO J 22:1497-1507.
5. Day CL, Chen L, Richardson SJ, Harrison PJ, Huang DCS, Hinds MG (2005) J Biol Chem 280:4738-4744.
6. Sattler M, Liang H, Nettesheim D, Meadows RP, Harlan JE, Eberstadt M, Yoon HS, Shuker SB, Chang BS, Minn AJ, et al. (1997) Science 275:983-986.
7. Petros AM, Nettseheim DG, Wang Y, Olejniczak ET, Meadows RP, Mack J, Swift K, Matayoshi ED, Zhang H, Thompson CB, et al. (2000) Protein Sci 9:2528-2534.
8. Liu X, Dai S, Zhu Y, Marrack P, Kappler JW (2003) Immunity 19:341-352.
9. Kozopas KM, Yang T, Buchan HL, Zhou P, Craig RW (1993) Proc Natl Acad Sci USA 90:3516-3520.
10. Rinkenberger JL, Horning S, Klocke B, Roth K, Korsmeyer SJ (2000) Genes Dev 14:23-27.
11. Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC, Korsmeyer SJ (2003) Nature 426:671-676.
12. Opferman J, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K, Korsmeyer SJ (2005) Science 307:1101-1104.
13. Yang T, Buchan HL, Townsend KJ, Craig RW (1996) J Cell Physiol 166:523-536.
14. Zhong Q, Gao W, Du F, Wang X (2005) Cell 121:1085-1095.
15. Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI, Adams JM, Huang DC (2005) Genes Dev 19:1294-1305.
16. Nijhawan D, Fang M, Traer E, Zhong Q, Gao W, Du F, Wang X (2003) Genes Dev 17:1475-1486.
17. Cuconati A, Mukherjee C, Perez D, White E (2003) Genes Dev 17:2922-2932.
18. Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DCS (2005) Mol Cell 17:393-403.
19. Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, Bruncko M, Deckwerth TL, Dinges J, Hajduk PJ, et al. (2005) Nature 435:677-681.
20. van Delft MF, Wei AH, Mason KD, Vandenberg CJ, Chen L, Czabotar PE, Willis SN, Scott CL, Day CL, Cory S, et al. (2006) Cancer Cell 10:389-399.
21. Michels J, O'Neill JW, Dallman CL, Mouzakiti A, Habens F, Brimmell M, Zhang KY, Craig RW, Marcusson EG, Johnson PW, et al. (2004) Oncogene 23:4818-4827.
22. Zhang B, Gojo I, Fenton RG (2002) Blood 99:1885-1893.
23. Alvi AJ, Austen B, Weston VJ, Fegan C, MacCallum D, Gianella-Borradori A, Lane DP, Hubank M, Powell JE, Wei W, et al. (2005) Blood 105:4484-4491.
24. Mei Y, Du W, Yang Y, Wu M (2005) Oncogene 24:7224-7237.
25. Yan N, Chai J, Lee ES, Gu L, Liu Q, He J, Wu JW, Kokel D, Li H, Hao Q, et al. (2005) Nature 437:831-837.
26. Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL (2007) Cell Death Differ 14:128-136.
27. Woo JS, Jung JS, Ha NC, Shin J, Kim KH, Lee W, Oh BH (2003) Cell Death Differ 10:1310-1319.
28. Van Parijs L, Refaeli Y, Abbas AK, Baltimore D (1999) Immunity 11:763-770.
29. Kinsella TM, Nolan GP (1996) Hum Gene Ther 7:1405-1413.
30. Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J (1993) J Mol Biol 229:105-124.
31. Day CL, Dupont C, Lackmann M, Vaux DL, Hinds MG (1999) Cell Death Differ 6:1125-1132.
32. Otwinowski Z, Minor W (1997) Methods Enzymol 276:307-326.
33. Pape T, Schneider TR (2004) J Appl Crystallogr 37:843-844.
34. Emsley P, Cowtan K (2004) Acta Crystallogr D 60:2126-2132.
35. Murshudov GN, Vagin AA, Dodson EJ (1997) Acta Crystallogr D 53:240-255.
36. Read RJ (2001) Acta Crystallogr D 57:1373-1382.
37. Storoni LC, McCoy AJ, Read RJ (2004) Acta Crystallogr D 60:432-438.
38. McCoy AJ, Grosse-Kunstleve RW, Storoni LC, Read RJ (2005) Acta Crystallogr D 61:458-464.
39. Sattler M, Schleucher J, Griesinger C (1999) Prog NMR Spectrosc 34:93-158.
40. Bartels C, Xia T-h, Billeter M, Güntert P, Wüthrich K (1995) J Biomol NMR 6:1-10.
41. Cornilescu G, Delaglio F, Bax A (1999) J Biomol NMR 13:289-302.
42. Vuister GW, Bax A (1993) J Am Chem Soc 115:7772-7777.
43. Guntert P (2004) Methods Mol Biol 278:353-378.
44. Schwieters CD, Kuszewski JJ, Clore GM (2006) Prog NMR Spectrosc 48:4.
45. Linge JP, Williams MA, Spronk CA, Bonvin AM, Nilges M (2003) Proteins 50:496-506.
46. Laskowski RA, Rullmannn JA, MacArthur MW, Kaptein R, Thornton JM (1996) J Biomol NMR 8:477-486.
47. Koradi R, Billeter M, Wuthrich K (1996) J Mol Graphics 14:51-55, 29-32.
48. Bashford D, Gerwert K (1992) J Mol Biol 224:473-486.
49. Sitkoff D, Sharp KA, Honig B (1994) J Phys Chem 98:1978-1988.