A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

EMBO Journal

Volumn 21, Issue 6, 2002, Pages 1315-1326

  Rossman, Kent L ^a   Worthylake, David K ^a   Snyder, Jason T ^a   Siderovski, David P ^a,b   Campbell, Sharon L ^a,b   Sondek, John ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Dbs; DH domain; PH domain; Rho GEF; Rho GTPase

Indexed keywords

DBS PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; NUCLEOTIDE; ONCOPROTEIN; PROTEIN CDC42; PROTEIN SOS1; PROTEIN SUBUNIT; PROTEIN TIAM1 RAC1; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME SPECIFICITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CDC42 GTP-BINDING PROTEIN; CRYSTALLOGRAPHY, X-RAY; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA;

EID: 0037086652     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.6.1315     Document Type: Article

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