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Volumn 11, Issue 15, 2010, Pages 2104-2107

High specificity in protein recognition by hydrogen-bond-surrogate α-helices: Selective inhibition of the p53/MDM2 complex

(4) Henchey, Laura K a Porter, Jason R b Ghosh, Indraneel b Arora, Paramjit S a

a NEW YORK UNIVERSITY (United States)

b University of Arizona (United States)

Author keywords

Helical structures; Inhibitors; Molecular recognition; Peptidomimetics; Protein protein interactions

Indexed keywords

PROTEIN MDM2; PROTEIN P53;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; HYDROGEN BOND; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MOLECULAR SEQUENCE DATA; PEPTIDES; PEPTIDOMIMETICS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79751501596 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201000378 Document Type: Article

Times cited : (78)

References (49)

1
- 57549092075
- L. K. Henchey, A. L. Jochim, P. S. Arora, Curr. Opin. Chem. Biol. 2008, 12, 692-697.
- (2008) Curr. Opin. Chem. Biol. , vol.12 , pp. 692-697
- Henchey, L.K.¹ Jochim, A.L.² Arora, P.S.³

2
- 35748977122
- J. Garner, M. M. Harding, Org. Biomol. Chem. 2007, 5, 3577-3585.
- (2007) Org. Biomol. Chem. , vol.5 , pp. 3577-3585
- Garner, J.¹ Harding, M.M.²

3
- 33846662867
- J. M. Davis, L. K. Tsou, A. D. Hamilton, Chem. Soc. Rev. 2007, 36, 326-334.
- (2007) Chem. Soc. Rev. , vol.36 , pp. 326-334
- Davis, J.M.¹ Tsou, L.K.² Hamilton, A.D.³

4
- 32044442488
- H. Yin, A. D. Hamilton, Angew. Chem. 2005, 117, 4200-4235.
- (2005) Angew. Chem. , vol.117 , pp. 4200-4235
- Yin, H.¹ Hamilton, A.D.²

5
- 22144454687
- H. Yin, A. D. Hamilton, Angew. Chem. Int. Ed. 2005, 44, 4130-4163.
- (2005) Angew. Chem. Int. Ed. , vol.44 , pp. 4130-4163
- Yin, H.¹ Hamilton, A.D.²

6
- 57349134690
- W. S. Horne, S. H. Gellman, Acc. Chem. Res. 2008, 41, 1399-1408.
- (2008) Acc. Chem. Res. , vol.41 , pp. 1399-1408
- Horne, W.S.¹ Gellman, S.H.²

7
- 57149097169
- D. Seebach, J. Gardiner, Acc. Chem. Res. 2008, 41, 1366-1375.
- (2008) Acc. Chem. Res. , vol.41 , pp. 1366-1375
- Seebach, D.¹ Gardiner, J.²

8
- 70449671729
- R. E. Moellering, M. Cornejo, T. N. Davis, C. Del Bianco, J. C. Aster, S. C. Blacklow, A. L. Kung, D. G. Gilliland, G. L. Verdine, J. E. Bradner, Nature 2009, 462, 182-188.
- (2009) Nature , vol.462 , pp. 182-188
- Moellering, R.E.¹ Cornejo, M.² Davis, T.N.³ Del Bianco, C.⁴ Aster, J.C.⁵ Blacklow, S.C.⁶ Kung, A.L.⁷ Gilliland, D.G.⁸ Verdine, G.L.⁹ Bradner, J.E.¹⁰

9
- 4444291734
- L. D. Walensky, A. L. Kung, I. Escher, T. J. Malia, S. Barbuto, R. D. Wright, G. Wagner, G. L. Verdine, S. J. Korsmeyer, Science 2004, 305, 1466-1470.
- (2004) Science , vol.305 , pp. 1466-1470
- Walensky, L.D.¹ Kung, A.L.² Escher, I.³ Malia, T.J.⁴ Barbuto, S.⁵ Wright, R.D.⁶ Wagner, G.⁷ Verdine, G.L.⁸ Korsmeyer, S.J.⁹

10
- 37249004920
- J. A. Wells, C. L. McClendon, Nature 2007, 450, 1001-1009.
- (2007) Nature , vol.450 , pp. 1001-1009
- Wells, J.A.¹ McClendon, C.L.²

11
- 3142781225
- M. R. Arkin, J. A. Wells, Nat. Rev. Drug. Discov. 2004, 3, 301-317.
- (2004) Nat. Rev. Drug. Discov. , vol.3 , pp. 301-317
- Arkin, M.R.¹ Wells, J.A.²

12
- 57349192372
- A. Patgiri, A. L. Jochim, P. S. Arora, Acc. Chem. Res. 2008, 41, 1289-1300.
- (2008) Acc. Chem. Res. , vol.41 , pp. 1289-1300
- Patgiri, A.¹ Jochim, A.L.² Arora, P.S.³

13
- 41549141350
- J. Liu, D. Wang, Q. Zheng, M. Lu, P. S. Arora, J. Am. Chem. Soc. 2008, 130, 4334-4337.
- (2008) J. Am. Chem. Soc. , vol.130 , pp. 4334-4337
- Liu, J.¹ Wang, D.² Zheng, Q.³ Lu, M.⁴ Arora, P.S.⁵

14
- 33750504670
- D. Wang, K. Chen, G. Dimartino, P. S. Arora, Org. Biomol. Chem. 2006, 4, 4074-4081.
- (2006) Org. Biomol. Chem. , vol.4 , pp. 4074-4081
- Wang, D.¹ Chen, K.² Dimartino, G.³ Arora, P.S.⁴

15
- 33746052447
- D. Wang, K. Chen, J. L. Kulp III, P. S. Arora, J. Am. Chem. Soc. 2006, 128, 9248-9256.
- (2006) J. Am. Chem. Soc. , vol.128 , pp. 9248-9256
- Wang, D.¹ Chen, K.² Kulp III, J.L.³ Arora, P.S.⁴

16
- 76149106544
- L. K. Henchey, S. Kushal, R. Dubey, R. N. Chapman, B. Z. Olenyuk, P. S. Arora, J. Am. Chem. Soc. 2010, 132, 941-943.
- (2010) J. Am. Chem. Soc. , vol.132 , pp. 941-943
- Henchey, L.K.¹ Kushal, S.² Dubey, R.³ Chapman, R.N.⁴ Olenyuk, B.Z.⁵ Arora, P.S.⁶

17
- 33846314134
- D. Wang, W. Liao, P. S. Arora, Angew. Chem. 2005, 117, 6683-6687.
- (2005) Angew. Chem. , vol.117 , pp. 6683-6687
- Wang, D.¹ Liao, W.² Arora, P.S.³

18
- 27144476545
- D. Wang, W. Liao, P. S. Arora, Angew. Chem. Int. Ed. 2005, 44, 6525-6529.
- (2005) Angew. Chem. Int. Ed. , vol.44 , pp. 6525-6529
- Wang, D.¹ Liao, W.² Arora, P.S.³

19
- 53849113877
- D. Wang, M. Lu, P. S. Arora, Angew. Chem. 2008, 120, 1905-1908.
- (2008) Angew. Chem. , vol.120 , pp. 1905-1908
- Wang, D.¹ Lu, M.² Arora, P.S.³

20
- 41549147161
- D. Wang, M. Lu, P. S. Arora, Angew. Chem. Int. Ed. 2008, 47, 1879-1882.
- (2008) Angew. Chem. Int. Ed. , vol.47 , pp. 1879-1882
- Wang, D.¹ Lu, M.² Arora, P.S.³

21
- 70349191067
- W. S. Horne, L. M. Johnson, T. J. Ketas, P. J. Klasse, M. Lu, J. P. Moore, S. H. Gellman, Proc. Natl. Acad. Sci. USA 2009, 106, 14751-14756.
- (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 14751-14756
- Horne, W.S.¹ Johnson, L.M.² Ketas, T.J.³ Klasse, P.J.⁴ Lu, M.⁵ Moore, J.P.⁶ Gellman, S.H.⁷

22
- 43949097245
- J. R. Porter, C. I. Stains, B. W. Jester, I. Ghosh, J. Am. Chem. Soc. 2008, 130, 6488-6497.
- (2008) J. Am. Chem. Soc. , vol.130 , pp. 6488-6497
- Porter, J.R.¹ Stains, C.I.² Jester, B.W.³ Ghosh, I.⁴

23
- 0037317840
- P. Chène, Nat. Rev. Cancer 2003, 3, 102-109.
- (2003) Nat. Rev. Cancer , vol.3 , pp. 102-109
- Chène, P.¹

24
- 10744221485
- L. T. Vassilev, B. T. Vu, B. Graves, D. Carvajal, F. Podlaski, Z. Filipovic, N. Kong, U. Kammlott, C. Lukacs, C. Klein, N. Fotouhi, E. A. Liu, Science 2004, 303, 844-848.
- (2004) Science , vol.303 , pp. 844-848
- Vassilev, L.T.¹ Vu, B.T.² Graves, B.³ Carvajal, D.⁴ Podlaski, F.⁵ Filipovic, Z.⁶ Kong, N.⁷ Kammlott, U.⁸ Lukacs, C.⁹ Klein, C.¹⁰ Fotouhi, N.¹¹ Liu, E.A.¹²

25
- 0030575937
- P. H. Kussie, S. Gorina, V. Marechal, B. Elenbaas, J. Moreau, A. J. Levine, N. P. Pavletich, Science 1996, 274, 948-953.
- (1996) Science , vol.274 , pp. 948-953
- Kussie, P.H.¹ Gorina, S.² Marechal, V.³ Elenbaas, B.⁴ Moreau, J.⁵ Levine, A.J.⁶ Pavletich, N.P.⁷

26
- 22144443750
- H. Yin, G. I. Lee, H. S. Park, G. A. Payne, J. M. Rodriguez, S. M. Sebti, A. D. Hamilton, Angew. Chem. 2005, 117, 2764-2767.
- (2005) Angew. Chem. , vol.117 , pp. 2764-2767
- Yin, H.¹ Lee, G.I.² Park, H.S.³ Payne, G.A.⁴ Rodriguez, J.M.⁵ Sebti, S.M.⁶ Hamilton, A.D.⁷

27
- 18844423053
- H. Yin, G. I. Lee, H. S. Park, G. A. Payne, J. M. Rodriguez, S. M. Sebti, A. D. Hamilton, Angew. Chem. Int. Ed. 2005, 44, 2704-2707.
- (2005) Angew. Chem. Int. Ed. , vol.44 , pp. 2704-2707
- Yin, H.¹ Lee, G.I.² Park, H.S.³ Payne, G.A.⁴ Rodriguez, J.M.⁵ Sebti, S.M.⁶ Hamilton, A.D.⁷

28
- 33847675805
- F. Bernal, A. F. Tyler, S. J. Korsmeyer, L. D. Walensky, G. L. Verdine, J. Am. Chem. Soc. 2007, 129, 2456-2457.
- (2007) J. Am. Chem. Soc. , vol.129 , pp. 2456-2457
- Bernal, F.¹ Tyler, A.F.² Korsmeyer, S.J.³ Walensky, L.D.⁴ Verdine, G.L.⁵

29
- 8744261570
- R. Fasan, R. L. Dias, K. Moehle, O. Zerbe, J. W. Vrijbloed, D. Obrecht, J. A. Robinson, Angew. Chem. 2004, 116, 2161-2164.
- (2004) Angew. Chem. , vol.116 , pp. 2161-2164
- Fasan, R.¹ Dias, R.L.² Moehle, K.³ Zerbe, O.⁴ Vrijbloed, J.W.⁵ Obrecht, D.⁶ Robinson, J.A.⁷

30
- 4544342753
- R. Fasan, R. L. Dias, K. Moehle, O. Zerbe, J. W. Vrijbloed, D. Obrecht, J. A. Robinson, Angew. Chem. Int. Ed. 2004, 43, 2109-2112.
- (2004) Angew. Chem. Int. Ed. , vol.43 , pp. 2109-2112
- Fasan, R.¹ Dias, R.L.² Moehle, K.³ Zerbe, O.⁴ Vrijbloed, J.W.⁵ Obrecht, D.⁶ Robinson, J.A.⁷

31
- 3543098742
- J. A. Kritzer, J. D. Lear, M. E. Hodsdon, A. Schepartz, J. Am. Chem. Soc. 2004, 126, 9468-9469.
- (2004) J. Am. Chem. Soc. , vol.126 , pp. 9468-9469
- Kritzer, J.A.¹ Lear, J.D.² Hodsdon, M.E.³ Schepartz, A.⁴

32
- 35048895357
- J. K. Murray, S. H. Gellman, Biopolymers 2007, 88, 657-686.
- (2007) Biopolymers , vol.88 , pp. 657-686
- Murray, J.K.¹ Gellman, S.H.²

33
- 69249101984
- J. P. Plante, T. Burnley, B. Malkova, M. E. Webb, S. L. Warriner, T. A. Edwards, A. J. Wilson, Chem. Commun. 2009, 5091-5093.
- (2009) Chem. Commun. , pp. 5091-5093
- Plante, J.P.¹ Burnley, T.² Malkova, B.³ Webb, M.E.⁴ Warriner, S.L.⁵ Edwards, T.A.⁶ Wilson, A.J.⁷

34
- 33748076161
- K. Sakurai, C. Schubert, D. Kahne, J. Am. Chem. Soc. 2006, 128, 11000-11001.
- (2006) J. Am. Chem. Soc. , vol.128 , pp. 11000-11001
- Sakurai, K.¹ Schubert, C.² Kahne, D.³

35
- 67849119649
- A. Shaginian, L. R. Whitby, S. Hong, I. Hwang, B. Farooqi, M. Searcey, J. Chen, P. K. Vogt, D. L. Boger, J. Am. Chem. Soc. 2009, 131, 5564-5572.
- (2009) J. Am. Chem. Soc. , vol.131 , pp. 5564-5572
- Shaginian, A.¹ Whitby, L.R.² Hong, S.³ Hwang, I.⁴ Farooqi, B.⁵ Searcey, M.⁶ Chen, J.⁷ Vogt, P.K.⁸ Boger, D.L.⁹

36
- 65249100143
- S. Shangary, S. Wang, Annu. Rev. Pharmacol. Toxicol. 2009, 49, 223-241.
- (2009) Annu. Rev. Pharmacol. Toxicol. , vol.49 , pp. 223-241
- Shangary, S.¹ Wang, S.²

37
- 73249140963
- S. Yu, D. Qin, S. Shangary, J. Chen, G. Wang, K. Ding, D. McEachern, S. Qiu, Z. Nikolovska-Coleska, R. Miller, S. Kang, D. Yang, S. Wang, J. Med. Chem. 2009, 52, 7970-7973.
- (2009) J. Med. Chem. , vol.52 , pp. 7970-7973
- Yu, S.¹ Qin, D.² Shangary, S.³ Chen, J.⁴ Wang, G.⁵ Ding, K.⁶ McEachern, D.⁷ Qiu, S.⁸ Nikolovska-Coleska, Z.⁹ Miller, R.¹⁰ Kang, S.¹¹ Yang, D.¹² Wang, S.¹³

38
- 33846285239
- R. N. Chapman, P. S. Arora, Org. Lett. 2006, 8, 5825-5828.
- (2006) Org. Lett. , vol.8 , pp. 5825-5828
- Chapman, R.N.¹ Arora, P.S.²

39
- 20544463029
- G. Dimartino, D. Wang, R. N. Chapman, P. S. Arora, Org. Lett. 2005, 7, 2389-2392.
- (2005) Org. Lett. , vol.7 , pp. 2389-2392
- Dimartino, G.¹ Wang, D.² Chapman, R.N.³ Arora, P.S.⁴

40
- 77950327807
- A. Patgiri, M. R. Witten, P. S. Arora, Org. Biomol. Chem. 2010, 8, 1773-1776.
- (2010) Org. Biomol. Chem. , vol.8 , pp. 1773-1776
- Patgiri, A.¹ Witten, M.R.² Arora, P.S.³

41
- 0037081033
- S. M. Knight, N. Umezawa, H. S. Lee, S. H. Gellman, B. K. Kay, Anal. Biochem. 2002, 300, 230-236.
- (2002) Anal. Biochem. , vol.300 , pp. 230-236
- Knight, S.M.¹ Umezawa, N.² Lee, H.S.³ Gellman, S.H.⁴ Kay, B.K.⁵

42
- 33749378169
- S. C. Zondlo, A. E. Lee, N. J. Zondlo, Biochemistry 2006, 45, 11945-11957.
- (2006) Biochemistry , vol.45 , pp. 11945-11957
- Zondlo, S.C.¹ Lee, A.E.² Zondlo, N.J.³

43
- 68949119587
- A. L. Jochim, P. S. Arora, Mol. BioSyst. 2009, 5, 924-926.
- (2009) Mol. BioSyst. , vol.5 , pp. 924-926
- Jochim, A.L.¹ Arora, P.S.²

44
- 1442310957
- A. M. Petros, E. T. Olejniczak, S. W. Fesik, Biochim. Biophys. Acta Mol. Cell Res. 2004, 1644, 83-94.
- (2004) Biochim. Biophys. Acta Mol. Cell Res. , vol.1644 , pp. 83-94
- Petros, A.M.¹ Olejniczak, E.T.² Fesik, S.W.³

45
- 0037117486
- S. A. Dames, M. Martinez-Yamout, R. N. De Guzman, H. J. Dyson, P. E. Wright, Proc. Natl. Acad. Sci. USA 2002, 99, 5271-5276.
- (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5271-5276
- Dames, S.A.¹ Martinez-Yamout, M.² De Guzman, R.N.³ Dyson, H.J.⁴ Wright, P.E.⁵

46
- 0037117479
- S. J. Freedman, Z. Y. Sun, F. Poy, A. L. Kung, D. M. Livingston, G. Wagner, M. J. Eck, Proc. Natl. Acad. Sci. USA 2002, 99, 5367-5372.
- (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5367-5372
- Freedman, S.J.¹ Sun, Z.Y.² Poy, F.³ Kung, A.L.⁴ Livingston, D.M.⁵ Wagner, G.⁶ Eck, M.J.⁷

47
- 77951224332
- D. Reed, Y. Shen, A. A. Shelat, L. A. Arnold, A. M. Ferreira, F. Zhu, N. Mills, D. C. Smithson, C. A. Regni, D. Bashford, S. A. Cicero, B. A. Schulman, A. G. Jochemsen, R. K. Guy, M. A. Dyer, J. Biol. Chem. 2010, 285, 10786-10796.
- (2010) J. Biol. Chem. , vol.285 , pp. 10786-10796
- Reed, D.¹ Shen, Y.² Shelat, A.A.³ Arnold, L.A.⁴ Ferreira, A.M.⁵ Zhu, F.⁶ Mills, N.⁷ Smithson, D.C.⁸ Regni, C.A.⁹ Bashford, D.¹⁰ Cicero, S.A.¹¹ Schulman, B.A.¹² Jochemsen, A.G.¹³ Guy, R.K.¹⁴ Dyer, M.A.¹⁵

48
- 4344656346
- K. E. Luker, M. C. P. Smith, G. D. Luker, S. T. Gammon, H. Piwnica-Worms, D. Piwnica-Worms, Proc. Natl. Acad. Sci. USA 2004, 101, 12288-12293.
- (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 12288-12293
- Luker, K.E.¹ Smith, M.C.P.² Luker, G.D.³ Gammon, S.T.⁴ Piwnica-Worms, H.⁵ Piwnica-Worms, D.⁶

49
- 0035984722
- A. Galarneau, M. Primeau, L.-E. Trudeau, S. W. Michnick, Nat. Biotechnol. 2002, 20, 619-622.
- (2002) Nat. Biotechnol. , vol.20 , pp. 619-622
- Galarneau, A.¹ Primeau, M.² Trudeau, L.-E.³ Michnick, S.W.⁴

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