-
1
-
-
34249337761
-
Perceptions of epigenetics
-
Bird A: Perceptions of epigenetics. Nature 447 (7143), 396-398 (2007).
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 396-398
-
-
Bird, A.1
-
2
-
-
54549109062
-
Language: Disputed definitions
-
Ledford H: Language: disputed definitions. Nature 455(7216), 1023-1028 (2008).
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1023-1028
-
-
Ledford, H.1
-
3
-
-
29244469466
-
The epigenetic progenitor origin of human cancer
-
Feinberg AP, Ohlsson R, Henikoff S: The epigenetic progenitor origin of human cancer. Nat. Rev. Genet. 7(1), 21-33 (2006).
-
(2006)
Nat. Rev. Genet.
, vol.7
, Issue.1
, pp. 21-33
-
-
Feinberg, A.P.1
Ohlsson, R.2
Henikoff, S.3
-
4
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M et al.: Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131(5), 861-872 (2007).
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
5
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4), 663-676 (2006).
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
6
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
Wernig M, Meissner A, Foreman R et al.: In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448(7151), 318-324 (2007).
-
(2007)
Nature
, vol.448
, Issue.7151
, pp. 318-324
-
-
Wernig, M.1
Meissner, A.2
Foreman, R.3
-
7
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
Yu J, Hu K, Smuga-Otto K et al.: Human induced pluripotent stem cells free of vector and transgene sequences. Science 324(5928), 797-801 (2009).
-
(2009)
Science
, vol.324
, Issue.5928
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otto, K.3
-
8
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K et al.: Induced pluripotent stem cell lines derived from human somatic cells. Science 318(5858), 1917-1920 (2007).
-
(2007)
Science
, vol.318
, Issue.5858
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
9
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park IH, Zhao R, West J A et al.: Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451(7175), 141-146(2008).
-
(2008)
Nature
, vol.451
, Issue.7175
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
-
10
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali N, Sridharan R, Xie W et al.: Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1(1), 55-70 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, Issue.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
-
11
-
-
42249094716
-
Chromatin dynamics during epigenetic reprogramming in the mouse germ line
-
Hajkova P, Ancelin K, Waldmann T et al.: Chromatin dynamics during epigenetic reprogramming in the mouse germ line. Nature 452(7189), 877-881 (2008).
-
(2008)
Nature
, vol.452
, Issue.7189
, pp. 877-881
-
-
Hajkova, P.1
Ancelin, K.2
Waldmann, T.3
-
12
-
-
37249012497
-
Histone acetylation and chromatin signature in stem cell identity and cancer
-
Shukla V, Vaissiere T, Herceg Z: Histone acetylation and chromatin signature in stem cell identity and cancer. Mutat. Res. 637(1-2), 1-15 (2008).
-
(2008)
Mutat. Res.
, vol.637
, Issue.1-2
, pp. 1-15
-
-
Shukla, V.1
Vaissiere, T.2
Herceg, Z.3
-
13
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
Visvader JE, Indeman GJ: Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 8(10), 755-768 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, Issue.10
, pp. 755-768
-
-
Visvader, J.E.1
Indeman, G.J.2
-
14
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans MJ, Kaufman MH: Establishment in culture of pluripotential cells from mouse embryos. Nature 292(5819), 154-156 (1981).
-
(1981)
Nature
, vol.292
, Issue.5819
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
15
-
-
0034614379
-
Stem cells: A new lease on life
-
Fuchs E, Segre JA: Stem cells: a new lease on life. Cell 100(1), 143-155 (2000).
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 143-155
-
-
Fuchs, E.1
Segre, J.A.2
-
16
-
-
35949000868
-
Open conformation chromatin and pluripotency
-
Niwa H: Open conformation chromatin and pluripotency. Gen. Dev. 21(21), 2671-2676 (2007).
-
(2007)
Gen. Dev.
, vol.21
, Issue.21
, pp. 2671-2676
-
-
Niwa, H.1
-
17
-
-
23944457397
-
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
-
Cowan CA, Atienza J, Melton DA, Eggan K: Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309(5739), 1369-1373 (2005).
-
(2005)
Science
, vol.309
, Issue.5739
, pp. 1369-1373
-
-
Cowan, C.A.1
Atienza, J.2
Melton, D.A.3
Eggan, K.4
-
18
-
-
33947301272
-
Epigenetic signatures of stem-cell identity
-
Spivakov M, Fisher AG: Epigenetic signatures of stem-cell identity. Nat. Rev. Genet. 8(4), 263-271 (2007).
-
(2007)
Nat. Rev. Genet.
, vol.8
, Issue.4
, pp. 263-271
-
-
Spivakov, M.1
Fisher, A.G.2
-
19
-
-
33646872978
-
Chromatin signatures of pluripotent cell lines
-
Azuara V, Perry P, Sauer S et al.: Chromatin signatures of pluripotent cell lines. Nat. Cell Biol. 8, 532-538 (2006).
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 532-538
-
-
Azuara, V.1
Perry, P.2
Sauer, S.3
-
20
-
-
33748274499
-
Human embryonic stem cells have a unique epigenetic signature
-
Bibikova M, Chudin E, Wu B et al.: Human embryonic stem cells have a unique epigenetic signature. Genome Res. 16(9), 1075-1083 (2006).
-
(2006)
Genome Res.
, vol.16
, Issue.9
, pp. 1075-1083
-
-
Bibikova, M.1
Chudin, E.2
Wu, B.3
-
21
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, Mikkelsen TS, Xie X et al.: A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125(2), 315-326 (2006).
-
(2006)
Cell
, vol.125
, Issue.2
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
-
22
-
-
33750379420
-
Polycomb silencers control cell fate, development and cancer
-
Sparmann A, van Lohuizen M: Polycomb silencers control cell fate, development and cancer. Nat. Rev. Cancer 6 (11), 846-856 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.11
, pp. 846-856
-
-
Sparmann, A.1
Van Lohuizen, M.2
-
23
-
-
29744447772
-
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells
-
Meshorer E, Yellajoshula D, George E et al.: Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev. Cell 10(1), 105-116(2006).
-
(2006)
Dev. Cell
, vol.10
, Issue.1
, pp. 105-116
-
-
Meshorer, E.1
Yellajoshula, D.2
George, E.3
-
24
-
-
33646037290
-
Searching chromatin for stem cell identity
-
Buszczak M, Spradling AC: Searching chromatin for stem cell identity. Cell 125(2), 233-236 (2006).
-
(2006)
Cell
, vol.125
, Issue.2
, pp. 233-236
-
-
Buszczak, M.1
Spradling, A.C.2
-
25
-
-
38149117952
-
Differentiation of human embryonic stem cells induces condensation of chromosome territories and formation of heterochromatin protein 1 foci
-
Bartova E, Krejci J, Harnicarova A, Kozubek S: Differentiation of human embryonic stem cells induces condensation of chromosome territories and formation of heterochromatin protein 1 foci. Differentiation 76(1), 24-32 (2008).
-
(2008)
Differentiation
, vol.76
, Issue.1
, pp. 24-32
-
-
Bartova, E.1
Krejci, J.2
Harnicarova, A.3
Kozubek, S.4
-
26
-
-
57149083688
-
Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation
-
Bartova E, Galiova G, Krejci J et al.: Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation. Dev. Dyn. 237(12), 3690-3702 (2008).
-
(2008)
Dev. Dyn.
, vol.237
, Issue.12
, pp. 3690-3702
-
-
Bartova, E.1
Galiova, G.2
Krejci, J.3
-
27
-
-
40349084105
-
Oct4 dependence of chromatin structure within the extended NANOG locus in ES cells
-
Levasseur DN, Wang J, Dorschner MO, Stamatoyannopoulos JA, Orkin SH: Oct4 dependence of chromatin structure within the extended NANOG locus in ES cells. Genes Dev. 22(5), 575-580 (2008).
-
(2008)
Genes Dev.
, vol.22
, Issue.5
, pp. 575-580
-
-
Levasseur, D.N.1
Wang, J.2
Dorschner, M.O.3
Stamatoyannopoulos, J.A.4
Orkin, S.H.5
-
28
-
-
46449119367
-
A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations
-
Tiwari VK, Cope L, McGarvey KM, Ohm JE, Baylin SB: A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations. Genome Res. 18(7), 1171-1179(2008).
-
(2008)
Genome Res.
, vol.18
, Issue.7
, pp. 1171-1179
-
-
Tiwari, V.K.1
Cope, L.2
McGarvey, K.M.3
Ohm, J.E.4
Baylin, S.B.5
-
29
-
-
84883798471
-
PcG proteins, DNA methylation, and gene repression by chromatin looping
-
Tiwari VK, McGarvey KM, Licchesi JD et al.: PcG proteins, DNA methylation, and gene repression by chromatin looping. PLoS Biol. 6(12), 2911-2927 (2008).
-
(2008)
PLoS Biol.
, vol.6
, Issue.12
, pp. 2911-2927
-
-
Tiwari, V.K.1
McGarvey, K.M.2
Licchesi, J.D.3
-
30
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T: Chromatin modifications and their function. Cell 128(4), 693-705 (2007).
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 693-705
-
-
Kouzarides, T.1
-
31
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD: The language of covalent histone modifications. Nature 403(6765), 41-45 (2000).
-
(2000)
Nature
, vol.403
, Issue.6765
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
32
-
-
33846569960
-
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
-
Ohm JE, McGarvey KM, Yu X et al.: A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat. Genet. 39(2), 237-242 (2007).
-
(2007)
Nat. Genet.
, vol.39
, Issue.2
, pp. 237-242
-
-
Ohm, J.E.1
McGarvey, K.M.2
Yu, X.3
-
33
-
-
34548434716
-
Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
-
Pan G, Tian S, Nie J et al.: Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1(3), 299-312 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, Issue.3
, pp. 299-312
-
-
Pan, G.1
Tian, S.2
Nie, J.3
-
34
-
-
8144230178
-
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
-
Pasini D, Bracken AP, Jensen MR, Lazzerini Denchi E, Helin K: Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 23(20), 4061-4071 (2004).
-
(2004)
EMBO J.
, vol.23
, Issue.20
, pp. 4061-4071
-
-
Pasini, D.1
Bracken, A.P.2
Jensen, M.R.3
Lazzerini Denchi, E.4
Helin, K.5
-
35
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
Lee TI, Jenner RG, Boyer LA et al.: Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125(2), 301-313 (2006).
-
(2006)
Cell
, vol.125
, Issue.2
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
-
36
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer LA, Plath K, Zeitlinger J et al.: Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441(7091), 9-53 (2006).
-
(2006)
Nature
, vol.441
, Issue.7091
, pp. 9-53
-
-
Boyer, L.A.1
Plath, K.2
Zeitlinger, J.3
-
37
-
-
35348993743
-
Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
-
Lee MG, Villa R, Trojer P et al.: Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science 318(5849), 447-450 (2007).
-
(2007)
Science
, vol.318
, Issue.5849
, pp. 447-450
-
-
Lee, M.G.1
Villa, R.2
Trojer, P.3
-
38
-
-
35148898348
-
A histone H3 lysine 27 demethylase regulates animal posterior development
-
Lan F, Bayliss PE, Rinn JL et al.: A histone H3 lysine 27 demethylase regulates animal posterior development. Nature 449(7163), 689-694 (2007).
-
(2007)
Nature
, vol.449
, Issue.7163
, pp. 689-694
-
-
Lan, F.1
Bayliss, P.E.2
Rinn, J.L.3
-
39
-
-
35148867907
-
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
-
Agger K, Cloos PA, Christensen J et al.: UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449(7163), 731-734 (2007).
-
(2007)
Nature
, vol.449
, Issue.7163
, pp. 731-734
-
-
Agger, K.1
Cloos, P.A.2
Christensen, J.3
-
40
-
-
47549105128
-
Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3
-
Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA: Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Gen. Dev. 22(14), 1865-1870 (2008).
-
(2008)
Gen. Dev.
, vol.22
, Issue.14
, pp. 1865-1870
-
-
Sen, G.L.1
Webster, D.E.2
Barragan, D.I.3
Chang, H.Y.4
Khavari, P.A.5
-
41
-
-
33846226977
-
Histone arginine methylation regulates pluripotency in the early mouse embryo
-
Torres-Padilla ME, Parfitt DE, Kouzarides T, Zernicka-Goetz M: Histone arginine methylation regulates pluripotency in the early mouse embryo. Nature 445(7124), 214-218 (2007).
-
(2007)
Nature
, vol.445
, Issue.7124
, pp. 214-218
-
-
Torres-Padilla, M.E.1
Parfitt, D.E.2
Kouzarides, T.3
Zernicka-Goetz, M.4
-
42
-
-
27144544622
-
Assembly of variant histones into chromatin
-
Henikoff S, Ahmad K: Assembly of variant histones into chromatin. Annu. Rev. Cell Dev. Biol. 21, 133-153 (2005).
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 133-153
-
-
Henikoff, S.1
Ahmad, K.2
-
43
-
-
33646239638
-
Histone H3 variants and their potential role in indexing mammalian genomes: The 'H3 barcode hypothesis'
-
Hake SB, Allis CD: Histone H3 variants and their potential role in indexing mammalian genomes: the 'H3 barcode hypothesis'. Proc. Natl Acad. Sci. USA 103(17), 6428-6435 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.17
, pp. 6428-6435
-
-
Hake, S.B.1
Allis, C.D.2
-
44
-
-
66449085586
-
Epigenetic reprogramming in mammalian reproduction: Contribution from histone variants
-
Santenard A, Torres-Padilla ME: Epigenetic reprogramming in mammalian reproduction: contribution from histone variants. Epigenetics 4(2), 80-84(2009).
-
(2009)
Epigenetics
, vol.4
, Issue.2
, pp. 80-84
-
-
Santenard, A.1
Torres-Padilla, M.E.2
-
45
-
-
35348856827
-
Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells
-
Dai B, Rasmussen TP: Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells. Stem Cells 25(10), 2567-2574 (2007).
-
(2007)
Stem Cells
, vol.25
, Issue.10
, pp. 2567-2574
-
-
Dai, B.1
Rasmussen, T.P.2
-
46
-
-
0037390327
-
Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development
-
Rangasamy D, Berven L, Ridgway P, Tremethick DJ: Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development. EMBO J. 22(7), 1599-1607 (2003).
-
(2003)
EMBO J.
, vol.22
, Issue.7
, pp. 1599-1607
-
-
Rangasamy, D.1
Berven, L.2
Ridgway, P.3
Tremethick, D.J.4
-
47
-
-
0034605124
-
Dynamic relocalization of histone MacroH2Al from centrosomes to inactive X chromosomes during X inactivation
-
Rasmussen TP, Mastrangelo MA, Eden A, Pehrson JR, Jaenisch R: Dynamic relocalization of histone MacroH2Al from centrosomes to inactive X chromosomes during X inactivation. J. Cell Biol. 150(5), 1189-1198(2000).
-
(2000)
J. Cell Biol.
, vol.150
, Issue.5
, pp. 1189-1198
-
-
Rasmussen, T.P.1
Mastrangelo, M.A.2
Eden, A.3
Pehrson, J.R.4
Jaenisch, R.5
-
48
-
-
70350459057
-
Characterisation of histone variant distribution in human embryonic stem cells by transfection of in vitro transcribed mRNA
-
Shaw ML, Williams EJ, Hawes S, Saffery R: Characterisation of histone variant distribution in human embryonic stem cells by transfection of in vitro transcribed mRNA. Mol. Reprod. Dev. 76(12), 1128-1142(2009).
-
(2009)
Mol. Reprod. Dev.
, vol.76
, Issue.12
, pp. 1128-1142
-
-
Shaw, M.L.1
Williams, E.J.2
Hawes, S.3
Saffery, R.4
-
49
-
-
55549148715
-
H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment
-
Creyghton MP, Markoulaki S, Levine SS et al.: H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment. Cell 135(4), 649-661 (2008).
-
(2008)
Cell
, vol.135
, Issue.4
, pp. 649-661
-
-
Creyghton, M.P.1
Markoulaki, S.2
Levine, S.S.3
-
50
-
-
61849118594
-
Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells
-
Wong LH, Ren H, Williams E et al.: Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells. Genome Res. 19(3), 404-414 (2009).
-
(2009)
Genome Res.
, vol.19
, Issue.3
, pp. 404-414
-
-
Wong, L.H.1
Ren, H.2
Williams, E.3
-
51
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A: DNA methylation patterns and epigenetic memory. Gen. Dev. 16(1), 6-21 (2002).
-
(2002)
Gen. Dev.
, vol.16
, Issue.1
, pp. 6-21
-
-
Bird, A.1
-
52
-
-
0023119242
-
Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
-
Monk M, Boubelik M, Lehnert S: Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development 99(3), 371-382 (1987).
-
(1987)
Development
, vol.99
, Issue.3
, pp. 371-382
-
-
Monk, M.1
Boubelik, M.2
Lehnert, S.3
-
54
-
-
45349086923
-
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
-
Farthing CR, Ficz G, Ng RK et al.: Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet. 4(6), E1000116(2008).
-
(2008)
PLoS Genet.
, vol.4
, Issue.6
-
-
Farthing, C.R.1
Ficz, G.2
Ng, R.K.3
-
55
-
-
59149084538
-
The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG Island shores
-
Irizarry RA, Ladd-Acosta C, Wen B et al.: The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores. Nat. Genet. 41(2), 178-186 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.2
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
-
56
-
-
34249279527
-
Stability and flexibility of epigenetic gene regulation in mammalian development
-
Reik W: Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447(7143), 425-432 (2007).
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 425-432
-
-
Reik, W.1
-
57
-
-
0026740497
-
Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line
-
Kafri T, Ariel M, Brandeis M et al.: Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line. Gen. Dev. 6(5), 705-714 (1992).
-
(1992)
Gen. Dev.
, vol.6
, Issue.5
, pp. 705-714
-
-
Kafri, T.1
Ariel, M.2
Brandeis, M.3
-
58
-
-
15744396825
-
Controlling DNA methylation: Many roads to one modification
-
Freitag M, Selker EU: Controlling DNA methylation: many roads to one modification. Curr. Opin. Genet. Dev. 15(2), 191-199 (2005).
-
(2005)
Curr. Opin. Genet. Dev.
, vol.15
, Issue.2
, pp. 191-199
-
-
Freitag, M.1
Selker, E.U.2
-
59
-
-
31544456085
-
The role of mammalian DNA methyltransferases in the regulation of gene expression
-
Turek-Plewa J, Jagodzinski PP: The role of mammalian DNA methyltransferases in the regulation of gene expression. Cell. Mol. Biol. Lett. 10(4), 631-647 (2005).
-
(2005)
Cell. Mol. Biol. Lett.
, vol.10
, Issue.4
, pp. 631-647
-
-
Turek-Plewa, J.1
Jagodzinski, P.P.2
-
60
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E: DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99(3), 247-257 (1999).
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
61
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R: Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69(6), 915-926 (1992).
-
(1992)
Cell
, vol.69
, Issue.6
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
62
-
-
0025816339
-
Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: Dna methylation alone is not sufficient to prevent protein binding in vivo
-
Weih F, Nitsch D, Reik A, Schutz G, Becker PB: Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: DNA methylation alone is not sufficient to prevent protein binding in vivo. EMBO J. 10(9), 2559-2567 (1991).
-
(1991)
EMBO J.
, vol.10
, Issue.9
, pp. 2559-2567
-
-
Weih, F.1
Nitsch, D.2
Reik, A.3
Schutz, G.4
Becker, P.B.5
-
64
-
-
0032572782
-
DNA methylation models histone acetylation
-
Eden S, Hashimshony T, Keshet I, Cedar H, Thome AW: DNA methylation models histone acetylation. Nature 394(6696), 842 (1998).
-
(1998)
Nature
, vol.394
, Issue.6696
, pp. 842
-
-
Eden, S.1
Hashimshony, T.2
Keshet, I.3
Cedar, H.4
Thome, A.W.5
-
65
-
-
0033601073
-
Methylation-induced repression - Belts, braces and chromatin
-
Bird AP, Wolffe AP: Methylation-induced repression - belts, braces and chromatin. Cell 99(5), 451-454 (1999).
-
(1999)
Cell
, vol.99
, Issue.5
, pp. 451-454
-
-
Bird, A.P.1
Wolffe, A.P.2
-
66
-
-
0035282458
-
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
-
Bannister AJ, Zegerman P, Partridge JF et al.: Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410(6824), 120-124(2001).
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 120-124
-
-
Bannister, A.J.1
Zegerman, P.2
Partridge, J.F.3
-
67
-
-
0035282573
-
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
-
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T: Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410(6824), 116-120 (2001).
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 116-120
-
-
Lachner, M.1
O'Carroll, D.2
Rea, S.3
Mechtler, K.4
Jenuwein, T.5
-
68
-
-
19944428231
-
Design principle of gene expression used by human stem cells: Implication for pluripotency
-
Golan-Mashiach M, Dazard JE, Gerecht-Nir S et al.: Design principle of gene expression used by human stem cells: implication for pluripotency. FASEB J. 19(1), 147-149 (2005).
-
(2005)
FASEB J.
, vol.19
, Issue.1
, pp. 147-149
-
-
Golan-Mashiach, M.1
Dazard, J.E.2
Gerecht-Nir, S.3
-
69
-
-
4744372577
-
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells
-
Jackson M, Krassowska A, Gilbert N et al.: Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol. Cell. Biol. 24(20), 8862-8871 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, Issue.20
, pp. 8862-8871
-
-
Jackson, M.1
Krassowska, A.2
Gilbert, N.3
-
70
-
-
27644478696
-
Global hypomethylation of the genome in XX embryonic stem cells
-
Zvetkova I, Apedaile A, Ramsahoye B et al.: Global hypomethylation of the genome in XX embryonic stem cells. Nat. Genet. 37(11), 1274-1279(2005).
-
(2005)
Nat. Genet.
, vol.37
, Issue.11
, pp. 1274-1279
-
-
Zvetkova, I.1
Apedaile, A.2
Ramsahoye, B.3
-
71
-
-
58849163959
-
MicroRNAs: Key regulators of stem cells
-
Gangaraju VK, Lin H: MicroRNAs: key regulators of stem cells. Nat. Rev. Mol. Cell Biol. 10(2), 116-125(2009).
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, Issue.2
, pp. 116-125
-
-
Gangaraju, V.K.1
Lin, H.2
-
72
-
-
58149235625
-
MicroRNAs in embryonic stem cells
-
Wang Y, Keys DN, Au-Young JK, Chen C: MicroRNAs in embryonic stem cells. J. Cell. Physiol. 218(2), 251-255 (2009).
-
(2009)
J. Cell. Physiol.
, vol.218
, Issue.2
, pp. 251-255
-
-
Wang, Y.1
Keys, D.N.2
Au-Young, J.K.3
Chen, C.4
-
73
-
-
63049103432
-
A study of microRNAs in silico and in vivo: Emerging regulators of embryonic stem cells
-
Kim KS, Kim JS, Lee MR, Jeong HS, Kim J: A study of microRNAs in silico and in vivo: emerging regulators of embryonic stem cells. FEBS J. 276(8), 2140-2149 (2009).
-
(2009)
FEBS J.
, vol.276
, Issue.8
, pp. 2140-2149
-
-
Kim, K.S.1
Kim, J.S.2
Lee, M.R.3
Jeong, H.S.4
Kim, J.5
-
74
-
-
11844262661
-
Phylogenetic shadowing and computational identification of human microRNA genes
-
Berezikov E, Guryev V, van de Belt J et al.: Phylogenetic shadowing and computational identification of human microRNA genes. Cell 120(1), 21-24(2005).
-
(2005)
Cell
, vol.120
, Issue.1
, pp. 21-24
-
-
Berezikov, E.1
Guryev, V.2
Van De Belt, J.3
-
75
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, function
-
Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, function. Cell 116(2), 281-297(2004).
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
77
-
-
0347755643
-
The microRNA registry
-
(Database issue)
-
Griffiths-Jones S: The microRNA registry. Nucleic Acids Res. 32(Database issue), D109-D111 (2004).
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Griffiths-Jones, S.1
-
78
-
-
34250877841
-
A mammalian microRNA expression atlas based on small RNA library sequencing
-
Landgraf P, Rusu M, Sheridan R et al.: A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129(7), 1401-1414 (2007).
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1401-1414
-
-
Landgraf, P.1
Rusu, M.2
Sheridan, R.3
-
79
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting RF, Fischer SE, Bernstein E et al.: Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15(20), 2654-2659 (2001).
-
(2001)
Genes Dev.
, vol.15
, Issue.20
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
-
80
-
-
0242266620
-
Dicer is essential for mouse development
-
Bernstein E, Kim SY, Carmell MA et al.: Dicer is essential for mouse development. Nat. Genet. 35(3), 215-217 (2003).
-
(2003)
Nat. Genet.
, vol.35
, Issue.3
, pp. 215-217
-
-
Bernstein, E.1
Kim, S.Y.2
Carmell, M.A.3
-
81
-
-
0242266618
-
The microRNA-producing enzyme Dicerl is essential for zebrafish development
-
Wienholds E, Koudijs MJ, van Eeden FJ, Cuppen E, Plasterk RH: The microRNA-producing enzyme Dicerl is essential for zebrafish development. Nat. Genet. 35(3), 217-218 (2003).
-
(2003)
Nat. Genet.
, vol.35
, Issue.3
, pp. 217-218
-
-
Wienholds, E.1
Koudijs, M.J.2
Van Eeden, F.J.3
Cuppen, E.4
Plasterk, R.H.5
-
82
-
-
40949130398
-
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
-
Sinkkonen L, Hugenschmidt T, Berninger P et al.: MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat. Struct. Mol. Biol. 15(3), 259-267 (2008).
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, Issue.3
, pp. 259-267
-
-
Sinkkonen, L.1
Hugenschmidt, T.2
Berninger, P.3
-
83
-
-
48449091318
-
Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence
-
Laurent LC, Chen J, Ulitsky I et al.: Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence. Stem Cell 26(6), 1506-1516 (2008).
-
(2008)
Stem Cell
, vol.26
, Issue.6
, pp. 1506-1516
-
-
Laurent, L.C.1
Chen, J.2
Ulitsky, I.3
-
84
-
-
2942534403
-
Human embryonic stem cells express a unique set of microRNAs
-
Suh MR, Lee Y, Kim JY et al.: Human embryonic stem cells express a unique set of microRNAs. Dev. Biol. 270(2), 488-498 (2004).
-
(2004)
Dev. Biol.
, vol.270
, Issue.2
, pp. 488-498
-
-
Suh, M.R.1
Lee, Y.2
Kim, J.Y.3
-
85
-
-
0042442335
-
Embryonic stem cell-specific microRNAs
-
Houbaviy HB, Murray MF, Sharp PA: Embryonic stem cell-specific microRNAs. Dev. Cell 5(2), 351-358 (2003).
-
(2003)
Dev. Cell
, vol.5
, Issue.2
, pp. 351-358
-
-
Houbaviy, H.B.1
Murray, M.F.2
Sharp, P.A.3
-
86
-
-
43449100341
-
REST maintains self-renewal and pluripotency of embryonic stem cells
-
Singh SK, Kagalwala MN, Parker-Thornburg J, Adams H, Majumder S: REST maintains self-renewal and pluripotency of embryonic stem cells. Nature 453(7192), 223-227 (2008).
-
(2008)
Nature
, vol.453
, Issue.7192
, pp. 223-227
-
-
Singh, S.K.1
Kagalwala, M.N.2
Parker-Thornburg, J.3
Adams, H.4
Majumder, S.5
-
87
-
-
54549108798
-
MicroRNAs to NANOG, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
-
Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I: MicroRNAs to NANOG, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 455(7216), 1124-1128(2008).
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1124-1128
-
-
Tay, Y.1
Zhang, J.2
Thomson, A.M.3
Lim, B.4
Rigoutsos, I.5
-
88
-
-
33144481470
-
Reciprocal actions of REST and a microRNA promote neuronal identity
-
Conaco C, Otto S, Han JJ, Mandel G: Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl Acad. Sci. USA 103(7), 2422-2427 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.7
, pp. 2422-2427
-
-
Conaco, C.1
Otto, S.2
Han, J.J.3
Mandel, G.4
-
89
-
-
41649106136
-
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
-
Morin RD, O'Connor MD, Griffith M et al.: Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res. 18(4), 610-621 (2008).
-
(2008)
Genome Res.
, vol.18
, Issue.4
, pp. 610-621
-
-
Morin, R.D.1
O'Connor, M.D.2
Griffith, M.3
-
90
-
-
66149131037
-
Target identification of microRNAs expressed highly in human embryonic stem cells
-
Li SS, Yu SL, Kao LP et al.: Target identification of microRNAs expressed highly in human embryonic stem cells. J. Cell. Biochem. 106(6), 1020-1030 (2009).
-
(2009)
J. Cell. Biochem.
, vol.106
, Issue.6
, pp. 1020-1030
-
-
Li, S.S.1
Yu, S.L.2
Kao, L.P.3
-
91
-
-
51349134161
-
Evolutionary emergence of microRNAs in human embryonic stem cells
-
Cao H, Yang CS, Rana TM: Evolutionary emergence of microRNAs in human embryonic stem cells. PLoS ONE 3(7), E2820 (2008).
-
(2008)
PLoS ONE
, vol.3
, Issue.7
-
-
Cao, H.1
Yang, C.S.2
Rana, T.M.3
-
92
-
-
50549095181
-
Let-7 microRNAs in development, stem cells and cancer
-
Bussing I, Slack FJ, Grosshans H: Let-7 microRNAs in development, stem cells and cancer. Trends Mol. Med. 14(9), 400-409 (2008).
-
(2008)
Trends Mol. Med.
, vol.14
, Issue.9
, pp. 400-409
-
-
Bussing, I.1
Slack, F.J.2
Grosshans, H.3
-
93
-
-
51349116001
-
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rb12-dependent regulation of DNA methyltransferases
-
Benetti R, Gonzalo S, Jaco I et al.: A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rb12-dependent regulation of DNA methyltransferases. Nat. Struct. Mol. Biol. 15(9), 998 (2008).
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, Issue.9
, pp. 998
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
-
94
-
-
34648821257
-
Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
-
Stingl J, Caldas C: Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat. Rev. Cancer 7(10), 791-799 (2007).
-
(2007)
Nat. Rev. Cancer
, vol.7
, Issue.10
, pp. 791-799
-
-
Stingl, J.1
Caldas, C.2
-
95
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot T, Sirard C, Vormoor J et al.: A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367(6464), 645-648 (1994).
-
(1994)
Nature
, vol.367
, Issue.6464
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
-
96
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3(7), 730-737 (1997).
-
(1997)
Nat. Med.
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
97
-
-
13344262695
-
Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis
-
Sirard C, Lapidot T, Vormoor J et al.: Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis. Blood 87(4), 1539-1548 (1996).
-
(1996)
Blood
, vol.87
, Issue.4
, pp. 1539-1548
-
-
Sirard, C.1
Lapidot, T.2
Vormoor, J.3
-
98
-
-
45149133254
-
CD34'CD38'CD19' as well as CD34'CD38 CD19' cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL
-
Kong Y, Yoshida S, Saito Y et al.: CD34'CD38'CD19' as well as CD34'CD38 CD19' cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL. Leukemia 22(6), 1207-1213 (2008).
-
(2008)
Leukemia
, vol.22
, Issue.6
, pp. 1207-1213
-
-
Kong, Y.1
Yoshida, S.2
Saito, Y.3
-
99
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
Krivtsov AV, Armstrong SA: MLL translocations, histone modifications and leukaemia stem-cell development. Nature rcvicws 7(11), 823-833 (2007).
-
(2007)
Nature Rcvicws
, vol.7
, Issue.11
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
100
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF: Prospective identification of tumorigenic breast cancer cells. Proc. Natl Acad. Sci. USA 100(7), 3983-3988 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
101
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID et al.: Identification of human brain tumour initiating cells. Nature 432(7015), 396-401 (2004).
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
102
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ: Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res. 65(23), 10946-10951 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.23
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
103
-
-
27144557960
-
A tumorigenic subpopulation with stem cell properties in melanomas
-
Fang D, Nguyen TK, Leishear K et al.: A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res. 65(20), 9328-9337 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.20
, pp. 9328-9337
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
-
104
-
-
38349165576
-
Identification of cells initiating human melanomas
-
Schatton T, Murphy GF, Frank NY et al.: Identification of cells initiating human melanomas. Nature 451 (7176), 345-349 (2008).
-
(2008)
Nature
, vol.451
, Issue.7176
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
-
105
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim CF, Jackson EL, Woolfenden AE et al.: Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121(6), 823-835 (2005).
-
(2005)
Cell
, vol.121
, Issue.6
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
-
106
-
-
34249980343
-
Identification and characterization of tumorigenic liver cancer stem/progenitor cells
-
Ma S, Chan KW, Hu L et al.: Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 132(7), 2542-2556 (2007).
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2542-2556
-
-
Ma, S.1
Chan, K.W.2
Hu, L.3
-
107
-
-
33847686753
-
CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity
-
Yin S, Li J, Hu C et al.: CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity. Int. J. Cancer 120(7), 1444-1450(2007).
-
(2007)
Int. J. Cancer
, vol.120
, Issue.7
, pp. 1444-1450
-
-
Yin, S.1
Li, J.2
Hu, C.3
-
108
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E et al.: Identification and expansion of human colon-cancer-initiating cells. Nature 445(7123), 111-115(2007).
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
-
109
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445(7123), 106-110 (2007).
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
110
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
Prince ME, Sivanandan R, Kaczorowski A et al.: Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc. Natl Acad. Sci. USA 104(3), 973-978 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.3
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
-
111
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P et al.: Identification of pancreatic cancer stem cells. Cancer Res. 67(3), 1030-1037 (2007).
-
(2007)
Cancer Res.
, vol.67
, Issue.3
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
-
113
-
-
49249091523
-
Identification and characterization of ovarian cancer-initiating cells from primary human tumors
-
Zhang S, Balch C, Chan MW et al.: Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res. 68(11), 4311-4320 (2008).
-
(2008)
Cancer Res.
, vol.68
, Issue.11
, pp. 4311-4320
-
-
Zhang, S.1
Balch, C.2
Chan, M.W.3
-
114
-
-
59049105873
-
Die hard: Are cancer stem cells the Bruce Willises of tumor biology?
-
Fabian A, Barok M, Vereb G, Szollosi J: Die hard: are cancer stem cells the Bruce Willises of tumor biology? Cytometry A 75(1), 67-74 (2009).
-
(2009)
Cytometry A
, vol.75
, Issue.1
, pp. 67-74
-
-
Fabian, A.1
Barok, M.2
Vereb, G.3
Szollosi, J.4
-
116
-
-
23844461316
-
Normal and neoplastic stem cells
-
discussion 50-54, 92-97
-
Weissman IL: Normal and neoplastic stem cells. Novartis Found. Symp. 265, 35-50; discussion 50-54, 92-97 (2005).
-
(2005)
Novartis Found. Symp.
, vol.265
, pp. 35-50
-
-
Weissman, I.L.1
-
117
-
-
33746773659
-
Dissecting self-renewal in stem cells with RNA interference
-
Ivanova N, Dobrin R, Lu R et al.: Dissecting self-renewal in stem cells with RNA interference. Nature 442(7102), 533-538 (2006).
-
(2006)
Nature
, vol.442
, Issue.7102
, pp. 533-538
-
-
Ivanova, N.1
Dobrin, R.2
Lu, R.3
-
118
-
-
0037131389
-
'Sternness': Transcriptional profiling of embryonic and adult stem cells
-
Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA: 'Sternness': transcriptional profiling of embryonic and adult stem cells. Science 298(5593), 597-600 (2002).
-
(2002)
Science
, vol.298
, Issue.5593
, pp. 597-600
-
-
Ramalho-Santos, M.1
Yoon, S.2
Matsuzaki, Y.3
Mulligan, R.C.4
Melton, D.A.5
-
119
-
-
0037130961
-
A stem cell molecular signature
-
Ivanova NB, Dimos JT, Schaniel C et al.: A stem cell molecular signature. Science 298(5593), 601-604 (2002).
-
(2002)
Science
, vol.298
, Issue.5593
, pp. 601-604
-
-
Ivanova, N.B.1
Dimos, J.T.2
Schaniel, C.3
-
120
-
-
0345687164
-
Gene-expression patterns in human embryonic stem cells and human pluripotent germ cell tumors
-
Sperger JM, Chen X, Draper JS et al.: Gene-expression patterns in human embryonic stem cells and human pluripotent germ cell tumors. Proc. Natl Acad. Sci. USA 100(23), 13350-13355 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.23
, pp. 13350-13355
-
-
Sperger, J.M.1
Chen, X.2
Draper, J.S.3
-
121
-
-
34147113900
-
A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas
-
Assou S, Le Carrour T, Tondeur S et al.: A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas. Stem Cells 25(4), 961-973 (2007).
-
(2007)
Stem Cells
, vol.25
, Issue.4
, pp. 961-973
-
-
Assou, S.1
Le Carrour, T.2
Tondeur, S.3
-
122
-
-
52149097555
-
Regulatory networks define phenotypic classes of human stem cell lines
-
Muller FJ, Laurent LC, Kostka D et al.: Regulatory networks define phenotypic classes of human stem cell lines. Nature 455(7211), 401-405(2008).
-
(2008)
Nature
, vol.455
, Issue.7211
, pp. 401-405
-
-
Muller, F.J.1
Laurent, L.C.2
Kostka, D.3
-
123
-
-
0036916369
-
Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity
-
Tanaka TS, Kunath T, Kimber WL et al.: Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity. Genome Res. 12(12), 1921-1928(2002).
-
(2002)
Genome Res.
, vol.12
, Issue.12
, pp. 1921-1928
-
-
Tanaka, T.S.1
Kunath, T.2
Kimber, W.L.3
-
124
-
-
27144536312
-
Gene expression signatures of seven individual human embryonic stem cell lines
-
Skottman H, Mikkola M, Lundin K et al.: Gene expression signatures of seven individual human embryonic stem cell lines. Stem cells 23(9), 1343-1356(2005).
-
(2005)
Stem Cells
, vol.23
, Issue.9
, pp. 1343-1356
-
-
Skottman, H.1
Mikkola, M.2
Lundin, K.3
-
125
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ et al.: An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat. Genet. 40(5), 499-507 (2008).
-
(2008)
Nat. Genet.
, vol.40
, Issue.5
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
-
126
-
-
47149102561
-
Gene-expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
-
Birnie R, Bryce SD, Roome C et al.: Gene-expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions. Genome Biol. 9(5), R83 (2008).
-
(2008)
Genome Biol.
, vol.9
, Issue.5
-
-
Birnie, R.1
Bryce, S.D.2
Roome, C.3
-
127
-
-
67349156673
-
Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature
-
Klarmann GJ, Hurt EM, Mathews LA et al.: Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature. Clin. Exp. Metastasis 26(5), 433-446 (2009).
-
(2009)
Clin. Exp. Metastasis
, vol.26
, Issue.5
, pp. 433-446
-
-
Klarmann, G.J.1
Hurt, E.M.2
Mathews, L.A.3
-
128
-
-
42249110515
-
Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice
-
Galie M, Konstantinidou G, Peroni D et al.: Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice. Oncogene 27(18), 2542-2551 (2008).
-
(2008)
Oncogene
, vol.27
, Issue.18
, pp. 2542-2551
-
-
Galie, M.1
Konstantinidou, G.2
Peroni, D.3
-
129
-
-
60549111070
-
Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
-
Charafe-Jauffret E, Ginestier C, Iovino F et al: Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res. 69(4), 1302-1313 (2009).
-
(2009)
Cancer Res.
, vol.69
, Issue.4
, pp. 1302-1313
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Iovino, F.3
-
130
-
-
61849178049
-
Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis
-
Ke XS, Qu Y, Rostad K et al.: Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis. PLoS ONE 4(3). E4687(2009).
-
(2009)
PLoS ONE
, vol.4
, Issue.3
-
-
Ke, X.S.1
Qu, Y.2
Rostad, K.3
-
131
-
-
45549098737
-
'Sternness' genomics law governs clinical behavior of human cancer: Implications for decision making in disease management
-
Glinsky GV: 'Sternness' genomics law governs clinical behavior of human cancer: implications for decision making in disease management. J. Clin. Oncol. 26(17), 2846-2853 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.17
, pp. 2846-2853
-
-
Glinsky, G.V.1
-
132
-
-
36349017912
-
A polycomb repression signature in metastatic prostate cancer predicts cancer outcome
-
Yu J, Yu J, Rhodes DR et al.: A polycomb repression signature in metastatic prostate cancer predicts cancer outcome. Cancer Res. 67(22), 10657-10663 (2007).
-
(2007)
Cancer Res.
, vol.67
, Issue.22
, pp. 10657-10663
-
-
Yu, J.1
Yu, J.2
Rhodes, D.R.3
-
133
-
-
53649093784
-
Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes
-
Metsuyanim S, Pode-Shakked N, Schmidt-Ott KM et al.: Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes. Stem Cells 26(7), 1808-1817 (2008).
-
(2008)
Stem Cells
, vol.26
, Issue.7
, pp. 1808-1817
-
-
Metsuyanim, S.1
Pode-Shakked, N.2
Schmidt-Ott, K.M.3
-
134
-
-
34848881905
-
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma
-
Calvisi DF, Ladu S, Gorden A et al.: Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma. J. Clin. Invest. 117(9), 2713-2722 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, Issue.9
, pp. 2713-2722
-
-
Calvisi, D.F.1
Ladu, S.2
Gorden, A.3
-
135
-
-
33644825262
-
Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage
-
Suzuki K, Suzuki I, Leodolter A et al.: Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage. Cancer Cell 9(3), 199-207 (2006).
-
(2006)
Cancer Cell
, vol.9
, Issue.3
, pp. 199-207
-
-
Suzuki, K.1
Suzuki, I.2
Leodolter, A.3
-
136
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB: The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3(6), 415-428 (2002).
-
(2002)
Nat. Rev. Genet.
, vol.3
, Issue.6
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
137
-
-
33644846509
-
Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
-
Baylin SB, Ohm JE: Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat. Rev. Cancer6(2), 107-116(2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.2
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
138
-
-
10344260184
-
CpG Island methylator phenotype in cancer
-
Issa JP: CpG island methylator phenotype in cancer. Nat. Rev. Cancer 4(12), 988-993 (2004).
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.12
, pp. 988-993
-
-
Issa, J.P.1
-
139
-
-
52949122883
-
Cell type-specific DNA methylation patterns in the human breast
-
Bloushtain-Qimron N, Yao J, Snyder EL et al.: Cell type-specific DNA methylation patterns in the human breast. Proc. Natl Acad. Sci. USA 105(37), 14076-14081 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.37
, pp. 14076-14081
-
-
Bloushtain-Qimron, N.1
Yao, J.2
Snyder, E.L.3
-
140
-
-
33847419142
-
Molecular definition of breast tumor heterogeneity
-
Shipitsin M, Campbell LL, Argani P et al: Molecular definition of breast tumor heterogeneity. Cancer Cell 11(3), 259-273 (2007).
-
(2007)
Cancer Cell
, vol.11
, Issue.3
, pp. 259-273
-
-
Shipitsin, M.1
Campbell, L.L.2
Argani, P.3
-
141
-
-
34347230100
-
Wnt pathway and breast cancer
-
Mohinta S, Wu H, Chaurasia P, Watabe K: Wnt pathway and breast cancer. Front. Biosci. 12, 4020-4033 (2007).
-
(2007)
Front. Biosci.
, vol.12
, pp. 4020-4033
-
-
Mohinta, S.1
Wu, H.2
Chaurasia, P.3
Watabe, K.4
-
142
-
-
47149097853
-
Epigenetic gene silencing in the Wnt pathway in breast cancer
-
Klarmann GJ, Decker A, Farrar WL: Epigenetic gene silencing in the Wnt pathway in breast cancer. Epigenetics 3(2), 59 (2008).
-
(2008)
Epigenetics
, vol.3
, Issue.2
, pp. 59
-
-
Klarmann, G.J.1
Decker, A.2
Farrar, W.L.3
-
143
-
-
36249025636
-
Wnt signaling, stem cells, and the cellular origin of breast cancer
-
Lindvall C, Bu W, Williams BO, Li Y: Wnt signaling, stem cells, and the cellular origin of breast cancer. Stem Cell Rev. 3(2), 157-168 (2007).
-
(2007)
Stem Cell Rev.
, vol.3
, Issue.2
, pp. 157-168
-
-
Lindvall, C.1
Bu, W.2
Williams, B.O.3
Li, Y.4
-
144
-
-
40949157661
-
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome
-
Cheng AS, Culhane AC, Chan MW et al.: Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome. Cancer Res. 68(6), 1786-1796 (2008).
-
(2008)
Cancer Res.
, vol.68
, Issue.6
, pp. 1786-1796
-
-
Cheng, A.S.1
Culhane, A.C.2
Chan, M.W.3
-
145
-
-
54749087165
-
Cancer genes hypermethylated in human embryonic stem cells
-
Calvanese V, Horrillo A, Hmadcha A et al.: Cancer genes hypermethylated in human embryonic stem cells. PLoS ONE 3 (9), E3294 (2008).
-
(2008)
PLoS ONE
, vol.3
, Issue.9
-
-
Calvanese, V.1
Horrillo, A.2
Hmadcha, A.3
-
146
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H et al: Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454(7205), 766-770 (2008).
-
(2008)
Nature
, vol.454
, Issue.7205
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
-
147
-
-
33846576622
-
Epigenetic stem cell signature in cancer
-
Widschwendter M, Fiegl H, Egle D et al: Epigenetic stem cell signature in cancer. Nat. Genet. 39(2), 157-158 (2007).
-
(2007)
Nat. Genet.
, vol.39
, Issue.2
, pp. 157-158
-
-
Widschwendter, M.1
Fiegl, H.2
Egle, D.3
-
148
-
-
33745633569
-
CIMPle origin for promoter hypermethylation in colorectal cancer? Nat
-
Schuebel K, Chen W, Baylin SB: CIMPle origin for promoter hypermethylation in colorectal cancer? Nat. Genet. 38(7), 738-740 (2006).
-
(2006)
Genet.
, vol.38
, Issue.7
, pp. 738-740
-
-
Schuebel, K.1
Chen, W.2
Baylin, S.B.3
-
149
-
-
65549107163
-
Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver
-
Brunner AL, Johnson DS, Kim SW et al.: Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver. Genome Res. 19(6), 1044-1056(2009).
-
(2009)
Genome Res.
, vol.19
, Issue.6
, pp. 1044-1056
-
-
Brunner, A.L.1
Johnson, D.S.2
Kim, S.W.3
-
150
-
-
57749090255
-
Methylation of polycomb target genes in intestinal cancer is mediated by inflammation
-
Hahn MA, Hahn T, Lee DH et al.: Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. Cancer Res. 68(24), 10280-10289 (2008).
-
(2008)
Cancer Res.
, vol.68
, Issue.24
, pp. 10280-10289
-
-
Hahn, M.A.1
Hahn, T.2
Lee, D.H.3
-
151
-
-
48649100069
-
Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells
-
McGarvey KM, Van Neste L, Cope L et al.: Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells. Cancer Res. 68(14), 5753-5759 (2008).
-
(2008)
Cancer Res.
, vol.68
, Issue.14
, pp. 5753-5759
-
-
McGarvey, K.M.1
Van Neste, L.2
Cope, L.3
-
152
-
-
32644452086
-
RNA interference in cancer
-
Gartel AL, Kandel ES: RNA interference in cancer. Biomol. Eng. 23(1), 17-34 (2006).
-
(2006)
Biomol. Eng.
, vol.23
, Issue.1
, pp. 17-34
-
-
Gartel, A.L.1
Kandel, E.S.2
-
153
-
-
67649556287
-
An elegant miRror: Micrornas in stem cells, developmental timing and cancer
-
Nimmo RA, Slack FJ: An elegant miRror: microRNAs in stem cells, developmental timing and cancer. Chromosoma 118(4), 405-418 (2009).
-
(2009)
Chromosoma
, vol.118
, Issue.4
, pp. 405-418
-
-
Nimmo, R.A.1
Slack, F.J.2
-
154
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD et al.: Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl Acad. Sci. USA 101(9), 2999-3004 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.9
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
-
155
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA et al.: MicroRNA expression profiles classify human cancers. Nature 435(7043), 834-838 (2005).
-
(2005)
Nature
, vol.435
, Issue.7043
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
-
156
-
-
2542626605
-
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
-
Takamizawa J, Konishi H, Yanagisawa K et al.: Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 64(11), 3753-3756 (2004).
-
(2004)
Cancer Res.
, vol.64
, Issue.11
, pp. 3753-3756
-
-
Takamizawa, J.1
Konishi, H.2
Yanagisawa, K.3
-
157
-
-
33747334621
-
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
-
Thomson JM, Newman M, Parker JS et al.: Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev. 20(16), 2202-2207 (2006).
-
(2006)
Genes Dev.
, vol.20
, Issue.16
, pp. 2202-2207
-
-
Thomson, J.M.1
Newman, M.2
Parker, J.S.3
-
158
-
-
51649083501
-
A microRNA DNA methylation signature for human cancer metastasis
-
Lujambio A, Calin GA, Villanueva A et al: A microRNA DNA methylation signature for human cancer metastasis. Proc. Natl Acad. Sci. USA 105(36), 13556-13561 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.36
, pp. 13556-13561
-
-
Lujambio, A.1
Calin, G.A.2
Villanueva, A.3
-
159
-
-
66249139268
-
Cell cycle regulation by MicroRNAs in embryonic stem cells
-
Wang Y, Bleiloch R: Cell cycle regulation by MicroRNAs in embryonic stem cells. Cancer Res. 69(10), 4093-4096 (2009).
-
(2009)
Cancer Res.
, vol.69
, Issue.10
, pp. 4093-4096
-
-
Wang, Y.1
Bleiloch, R.2
-
160
-
-
36849078711
-
Let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
Yu F, Yao H, Zhu P et al: Let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 131(6), 1109-1123(2007).
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
-
161
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
Iorio MV, Ferracin M, Liu CG et al: MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 65(16), 7065-7070 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.16
, pp. 7065-7070
-
-
Iorio, M.V.1
Ferracin, M.2
Liu, C.G.3
-
162
-
-
34547463506
-
Let-7 expression defines two differentiation stages of cancer
-
Shell S, Park SM, Radjabi AR et al: Let-7 expression defines two differentiation stages of cancer. Proc. Natl Acad. Sci. USA 104(27), 11400-11405(2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.27
, pp. 11400-11405
-
-
Shell, S.1
Park, S.M.2
Radjabi, A.R.3
-
163
-
-
36849023466
-
Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2
-
Park SM, Shell S, Radjabi AR et al: Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2. Cell Cycle 6(21), 2585-2590 (2007).
-
(2007)
Cell Cycle
, vol.6
, Issue.21
, pp. 2585-2590
-
-
Park, S.M.1
Shell, S.2
Radjabi, A.R.3
-
164
-
-
68049114782
-
Downrcgulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono Y, Zabala M, Cho RW et al.: Downrcgulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138(3), 592-603 (2009).
-
(2009)
Cell
, vol.138
, Issue.3
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
-
165
-
-
33644518372
-
Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation
-
Su X, Gopalakrishnan V, Stearns D et al.: Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation. Mol. Cell. Biol. 26(5), 1666-1678 (2006).
-
(2006)
Mol. Cell. Biol.
, vol.26
, Issue.5
, pp. 1666-1678
-
-
Su, X.1
Gopalakrishnan, V.2
Stearns, D.3
-
166
-
-
20144382025
-
International patterns and trends in testis cancer incidence
-
Purdue MP, Devesa SS, Sigurdson AJ, McGlynn KA: International patterns and trends in testis cancer incidence. Int. J. Cancer 115(5), 822-827(2005).
-
(2005)
Int. J. Cancer
, vol.115
, Issue.5
, pp. 822-827
-
-
Purdue, M.P.1
Devesa, S.S.2
Sigurdson, A.J.3
McGlynn, K.A.4
-
167
-
-
33645970670
-
Trends in testicular cancer incidence and mortality in 22 European countries: Continuing increases in incidence and declines in mortality
-
Bray F, Richiardi L, Ekbom A et al.: Trends in testicular cancer incidence and mortality in 22 European countries: continuing increases in incidence and declines in mortality. Int. J. Cancer 118(12), 3099-3111 (2006).
-
(2006)
Int. J. Cancer
, vol.118
, Issue.12
, pp. 3099-3111
-
-
Bray, F.1
Richiardi, L.2
Ekbom, A.3
-
170
-
-
33846142847
-
Of mice and men: Teratomas and teratocarcinomas
-
Bulic-Jakus F, Ulamec M, Vlahovic M et al.: Of mice and men: teratomas and teratocarcinomas. Coll. Antropol. 30(4), 921-924 (2006).
-
(2006)
Coll. Antropol.
, vol.30
, Issue.4
, pp. 921-924
-
-
Bulic-Jakus, F.1
Ulamec, M.2
Vlahovic, M.3
-
171
-
-
36548999753
-
In vivo differentiation and genomic evolution in adult male germ cell tumors
-
Korkola JE, Heck S, Olshen AB et al.: In vivo differentiation and genomic evolution in adult male germ cell tumors. Genes Chromosomes Cancer 47(1), 43-55 (2008).
-
(2008)
Genes Chromosomes Cancer
, vol.47
, Issue.1
, pp. 43-55
-
-
Korkola, J.E.1
Heck, S.2
Olshen, A.B.3
-
172
-
-
31544440121
-
Downregulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in vivo differentiation of human male germ cell tumors
-
Korkola JE, Houldsworth J, Chadalavada RS et al.: Downregulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in vivo differentiation of human male germ cell tumors. Cancer Res. 66(2), 820-827 (2006).
-
(2006)
Cancer Res.
, vol.66
, Issue.2
, pp. 820-827
-
-
Korkola, J.E.1
Houldsworth, J.2
Chadalavada, R.S.3
-
173
-
-
57749105455
-
Global DNA hypomethylation in intratubular germ cell Neoplasia and Seminoma, but not in nonseminomatous male germ cell tumors
-
Netto GJ, Nakai Y, Nakayama M et al.: Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors. Mod. Pathol. 21(11), 1337-1344 (2008).
-
(2008)
Mod. Pathol.
, vol.21
, Issue.11
, pp. 1337-1344
-
-
Netto, G.J.1
Nakai, Y.2
Nakayama, M.3
-
174
-
-
0016167678
-
Neoplasms, differentiations and mutations
-
Pierce GB: Neoplasms, differentiations and mutations. Am. J. Pathol. 77(1), 103-118 (1974).
-
(1974)
Am. J. Pathol.
, vol.77
, Issue.1
, pp. 103-118
-
-
Pierce, G.B.1
-
175
-
-
84883845299
-
Multipotentiality of single embryonal carcinoma cells
-
Kleinsmith LJ, Pierce GB Jr: Multipotentiality of single embryonal carcinoma cells. Cancer Res. 24, 1544-1551 (1964).
-
(1964)
Cancer Res.
, vol.24
, pp. 1544-1551
-
-
Kleinsmith, L.J.1
Pierce Jr., G.B.2
-
176
-
-
33748454496
-
From stem cells to germ cell tumors and back
-
Damjanov I: From stem cells to germ cell tumors and back. Verh. Dtsch. Ges. Pathol. 88, 39-44 (2004).
-
(2004)
Verh. Dtsch. Ges. Pathol.
, vol.88
, pp. 39-44
-
-
Damjanov, I.1
-
177
-
-
0037192921
-
From teratocarcinomas to embryonic stem cells
-
Andrews PW: From teratocarcinomas to embryonic stem cells. Philos. Trans. R. Soc. Lond. B Biol. Sci. 357(1420), 405-417 (2002).
-
(2002)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.357
, Issue.1420
, pp. 405-417
-
-
Andrews, P.W.1
-
178
-
-
0014834055
-
Extrauterine growth of mouse egg-cylinders results in malignant teratoma
-
Solter D, Skreb N, Damjanov I: Extrauterine growth of mouse egg-cylinders results in malignant teratoma. Nature 227(5257), 503-504 (1970).
-
(1970)
Nature
, vol.227
, Issue.5257
, pp. 503-504
-
-
Solter, D.1
Skreb, N.2
Damjanov, I.3
-
179
-
-
0345366593
-
Normal genetically mosaic mice produced from malignant teratocarcinoma cells
-
Mintz B, Illmensee K: Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proc. Natl Acad. Sci. USA 72(9), 3585-3589 (1975).
-
(1975)
Proc. Natl Acad. Sci. USA
, vol.72
, Issue.9
, pp. 3585-3589
-
-
Mintz, B.1
Illmensee, K.2
-
180
-
-
33751503182
-
Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1)
-
Lind GE, Skotheim RI, Fraga MF et al.: Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1). J. Pathol. 210(4), 441-449 (2006).
-
(2006)
J. Pathol.
, vol.210
, Issue.4
, pp. 441-449
-
-
Lind, G.E.1
Skotheim, R.I.2
Fraga, M.F.3
-
181
-
-
0037461896
-
Frequent epigenetic inactivation of the RASSFIA tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours
-
Honorio S, Agathanggelou A, Wernett N et al.: Frequent epigenetic inactivation of the RASSFIA tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours. Oncogene 22(3), 461-466 (2003).
-
(2003)
Oncogene
, vol.22
, Issue.3
, pp. 461-466
-
-
Honorio, S.1
Agathanggelou, A.2
Wernett, N.3
-
182
-
-
0043023455
-
Multipoint methylation analysis indicates a distinctive epigenetic phenotype among testicular germ cell tumors and testicular malignant lymphomas
-
Kawakami T, Okamoto K, Kataoka A et al.: Multipoint methylation analysis indicates a distinctive epigenetic phenotype among testicular germ cell tumors and testicular malignant lymphomas. Genes Chromosomes Cancer 38(1), 97-101 (2003).
-
(2003)
Genes Chromosomes Cancer
, vol.38
, Issue.1
, pp. 97-101
-
-
Kawakami, T.1
Okamoto, K.2
Kataoka, A.3
-
183
-
-
34547883568
-
Differential methylation of the OCT3/4 upstream region in primary human testicular germ cell tumors
-
De Jong J, Weeda S, Gillis AJ, Oosterhuis JW, Looijenga LH: Differential methylation of the OCT3/4 upstream region in primary human testicular germ cell tumors. Oncol. Rep. 18(1), 127-132(2007).
-
(2007)
Oncol. Rep.
, vol.18
, Issue.1
, pp. 127-132
-
-
De Jong, J.1
Weeda, S.2
Gillis, A.J.3
Oosterhuis, J.W.4
Looijenga, L.H.5
-
184
-
-
34447303847
-
Embryonic stem cell transcription factor signatures in the diagnosis of primary and metastatic germ cell tumors
-
Santagata S, Ligon KL, Hornick JL: Embryonic stem cell transcription factor signatures in the diagnosis of primary and metastatic germ cell tumors. Am. J. Surg. Pathol. 31(6), 836-845 (2007).
-
(2007)
Am. J. Surg. Pathol.
, vol.31
, Issue.6
, pp. 836-845
-
-
Santagata, S.1
Ligon, K.L.2
Hornick, J.L.3
-
185
-
-
34047169674
-
Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: History and future
-
de Jong J, Looijenga LH: Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future. Crit. Rev. Oncog. 12(3-4), 171-203 (2006).
-
(2006)
Crit. Rev. Oncog.
, vol.12
, Issue.3-4
, pp. 171-203
-
-
De Jong, J.1
Looijenga, L.H.2
-
186
-
-
68949131095
-
A role for Lin28 in primordial germ-cell development and germ-cell malignancy
-
West JA, Viswanathan SR, Yabuuchi A et al.: A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Nature 460(7257), 909-913 (2009).
-
(2009)
Nature
, vol.460
, Issue.7257
, pp. 909-913
-
-
West, J.A.1
Viswanathan, S.R.2
Yabuuchi, A.3
-
187
-
-
20444457518
-
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
-
Glinsky GV, Berezovska O, Glinskii AB: Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J. Clin. Invest. 115(6), 1503-1521 (2005)
-
(2005)
J. Clin. Invest.
, vol.115
, Issue.6
, pp. 1503-1521
-
-
Glinsky, G.V.1
Berezovska, O.2
Glinskii, A.B.3
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