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Volumn 3, Issue 9, 2008, Pages

Cancer genes hypermethylated in human embryonic stem cells

(23)  Calvanese, Vincenzo a   Horrillo, Angelica b   Hmadcha, Abdelkrim b   Suarez Álvarez, Beatriz c   Fernandez, Agustín F a,d   Lara, Ester a   Casado, Sara a   Menendez, Pablo e   Bueno, Clara e   Garcia Castro, Javier e   Rubio, Ruth e   Lapunzina, Pablo f   Alaminos, Miguel e   Borghese, Lodovica g   Terstegge, Stefanie g   Harrison, Neil J h   Moore, Harry D h   Brüstle, Oliver g   Lopez Larrea, Carlos c   Andrews, Peter W h   more..

c HUCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER GENETICS; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA DAMAGE; DNA DETERMINATION; DNA METHYLATION; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; MALIGNANT NEOPLASTIC DISEASE; PROMOTER REGION; TUMOR SUPPRESSOR GENE; CELL LINE; CELL STRAIN HL 60; CELL STRAIN U937; CHROMATIN; CYTOLOGY; GENETICS; HELA CELL; METABOLISM; NEOPLASM; TIME; TUMOR GENE;

EID: 54749087165     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003294     Document Type: Article
Times cited : (73)

References (39)
  • 1
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W (2007) Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447: 425-432.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 2
    • 18344372018 scopus 로고    scopus 로고
    • The RUNX genes: Gain or loss of function in cancer
    • Blyth K, Cameron ER, Neil JC (2005) The RUNX genes: gain or loss of function in cancer. Nat Rev Cancer 5: 376-387.
    • (2005) Nat Rev Cancer , vol.5 , pp. 376-387
    • Blyth, K.1    Cameron, E.R.2    Neil, J.C.3
  • 4
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125: 315-326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5
  • 5
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, et al. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125: 301-313.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3    Guenther, M.G.4    Levine, S.S.5
  • 6
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • Sparmann A, van Lohuizen M (2006) Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 6: 846-856.
    • (2006) Nat Rev Cancer , vol.6 , pp. 846-856
    • Sparmann, A.1    van Lohuizen, M.2
  • 7
    • 33846649587 scopus 로고    scopus 로고
    • Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
    • Schlesinger Y, Straussman R, Keshet I, Farkash S, Hecht M, et al. (2007) Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet 39: 232-236.
    • (2007) Nat Genet , vol.39 , pp. 232-236
    • Schlesinger, Y.1    Straussman, R.2    Keshet, I.3    Farkash, S.4    Hecht, M.5
  • 8
    • 33846569960 scopus 로고    scopus 로고
    • A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
    • Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, et al. (2007) A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 39: 237-242.
    • (2007) Nat Genet , vol.39 , pp. 237-242
    • Ohm, J.E.1    McGarvey, K.M.2    Yu, X.3    Cheng, L.4    Schuebel, K.E.5
  • 10
    • 12344266614 scopus 로고    scopus 로고
    • 5-azacytidine induces cardiac differentiation of P19 embryonic stem cells
    • Choi SC, Yoon J, Shim WJ, Ro YM, Lim DS (2004) 5-azacytidine induces cardiac differentiation of P19 embryonic stem cells. Exp Mol Med 36: 515-523.
    • (2004) Exp Mol Med , vol.36 , pp. 515-523
    • Choi, S.C.1    Yoon, J.2    Shim, W.J.3    Ro, Y.M.4    Lim, D.S.5
  • 11
    • 33748274499 scopus 로고    scopus 로고
    • Human embryonic stem cells have a unique epigenetic signature
    • Bibikova M, Chudin E, Wu B, Zhou L, Garcia EW, et al. (2006) Human embryonic stem cells have a unique epigenetic signature. Genome Res 16: 1075-1083.
    • (2006) Genome Res , vol.16 , pp. 1075-1083
    • Bibikova, M.1    Chudin, E.2    Wu, B.3    Zhou, L.4    Garcia, E.W.5
  • 12
    • 34548424709 scopus 로고    scopus 로고
    • Whole-Genome Mapping of Histone H3 Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells
    • Zhao XD, Han X, Chew JL, Liu J, Chiu KP, et al. (2007) Whole-Genome Mapping of Histone H3 Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells. Cell Stem Cell 1: 286-298.
    • (2007) Cell Stem Cell , vol.1 , pp. 286-298
    • Zhao, X.D.1    Han, X.2    Chew, J.L.3    Liu, J.4    Chiu, K.P.5
  • 13
    • 49249126998 scopus 로고    scopus 로고
    • Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies
    • Fraga MF, Berdasco M, Ballestar E, Ropero S, Lopez-Nieva P, et al. (2008) Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies. Cancer Res 68: 4116-4122.
    • (2008) Cancer Res , vol.68 , pp. 4116-4122
    • Fraga, M.F.1    Berdasco, M.2    Ballestar, E.3    Ropero, S.4    Lopez-Nieva, P.5
  • 14
    • 34249897719 scopus 로고    scopus 로고
    • Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome
    • Allegrucci C, Wu YZ, Thurston A, Denning CN, Priddle H, et al. (2007) Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome. Hum Mol Genet 16: 1253-1268.
    • (2007) Hum Mol Genet , vol.16 , pp. 1253-1268
    • Allegrucci, C.1    Wu, Y.Z.2    Thurston, A.3    Denning, C.N.4    Priddle, H.5
  • 15
  • 16
    • 34547624303 scopus 로고    scopus 로고
    • Genomewide maps of chromatin state in pluripotent and lineage-committed cells
    • Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, et al. (2007) Genomewide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448: 553-560.
    • (2007) Nature , vol.448 , pp. 553-560
    • Mikkelsen, T.S.1    Ku, M.2    Jaffe, D.B.3    Issac, B.4    Lieberman, E.5
  • 17
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, et al. (2000) Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343: 1350-1354.
    • (2000) N Engl J Med , vol.343 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3    Goodman, S.N.4    Hidalgo, O.F.5
  • 18
    • 0038153876 scopus 로고    scopus 로고
    • SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers
    • Li H, Myeroff L, Smiraglia D, Romero MF, Pretlow TP, et al. (2003) SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers. Proc Natl Acad Sci U S A 100: 8412-8417.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8412-8417
    • Li, H.1    Myeroff, L.2    Smiraglia, D.3    Romero, M.F.4    Pretlow, T.P.5
  • 19
    • 0033676843 scopus 로고    scopus 로고
    • TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers
    • Conway KE, McConnell BB, Bowring CE, Donald CD, Warren ST, et al. (2000) TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers. Cancer Res 60: 6236-6242.
    • (2000) Cancer Res , vol.60 , pp. 6236-6242
    • Conway, K.E.1    McConnell, B.B.2    Bowring, C.E.3    Donald, C.D.4    Warren, S.T.5
  • 20
    • 18344389720 scopus 로고    scopus 로고
    • Causal relationship between the loss of RUNX3 expression and gastric cancer
    • Li QL, Ito K, Sakakura C, Fukamachi H, Inoue K, et al. (2002) Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 109: 113-124.
    • (2002) Cell , vol.109 , pp. 113-124
    • Li, Q.L.1    Ito, K.2    Sakakura, C.3    Fukamachi, H.4    Inoue, K.5
  • 21
    • 33744989977 scopus 로고    scopus 로고
    • Assessing self-renewal and differentiation in human embryonic stem cell lines
    • Cai J, Chen J, Liu Y, Miura T, Luo Y, et al. (2006) Assessing self-renewal and differentiation in human embryonic stem cell lines. Stem Cells 24: 516-530.
    • (2006) Stem Cells , vol.24 , pp. 516-530
    • Cai, J.1    Chen, J.2    Liu, Y.3    Miura, T.4    Luo, Y.5
  • 22
    • 34249744340 scopus 로고    scopus 로고
    • Tumor-specific methylation of the 8p22 tumor suppressor gene DLC1 is an epigenetic biomarker for Hodgkin, nasal NK/T-cell and other types of lymphomas
    • Ying J, Li H, Murray P, Gao Z, Chen YW, et al. (2007) Tumor-specific methylation of the 8p22 tumor suppressor gene DLC1 is an epigenetic biomarker for Hodgkin, nasal NK/T-cell and other types of lymphomas. Epigenetics 2: 15-21.
    • (2007) Epigenetics , vol.2 , pp. 15-21
    • Ying, J.1    Li, H.2    Murray, P.3    Gao, Z.4    Chen, Y.W.5
  • 23
    • 0037438985 scopus 로고    scopus 로고
    • Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers
    • Yuan BZ, Durkin ME, Popescu NC (2003) Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers. Cancer Genet Cytogenet 140: 113-117.
    • (2003) Cancer Genet Cytogenet , vol.140 , pp. 113-117
    • Yuan, B.Z.1    Durkin, M.E.2    Popescu, N.C.3
  • 24
    • 34548483170 scopus 로고    scopus 로고
    • Transitional CpG methylation between promoters and retroelements of tissue-specific genes during human mesenchymal cell differentiation
    • Kang MI, Kim HS, Jung YC, Kim YH, Hong SJ, et al. (2007) Transitional CpG methylation between promoters and retroelements of tissue-specific genes during human mesenchymal cell differentiation. J Cell Biochem 102: 224-239.
    • (2007) J Cell Biochem , vol.102 , pp. 224-239
    • Kang, M.I.1    Kim, H.S.2    Jung, Y.C.3    Kim, Y.H.4    Hong, S.J.5
  • 25
    • 35349011610 scopus 로고    scopus 로고
    • The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers
    • Woerner SM, Kloor M, Schwitalle Y, Youmans H, Doeberitz MK, et al. (2007) The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers. Genes Chromosomes Cancer 46: 1080-1089.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 1080-1089
    • Woerner, S.M.1    Kloor, M.2    Schwitalle, Y.3    Youmans, H.4    Doeberitz, M.K.5
  • 26
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg AP, Tycko B (2004) The history of cancer epigenetics. Nat Rev Cancer 4: 143-153.
    • (2004) Nat Rev Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 27
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB (2007) The epigenomics of cancer. Cell 128: 683-692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 28
    • 38649126918 scopus 로고    scopus 로고
    • Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation. Cell Stem
    • Fouse SD, Shen Y, Pellegrini M, Cole S, Meissner A, et al. (2008) Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation. Cell Stem Cell 2: 160-169.
    • (2008) Cell , vol.2 , pp. 160-169
    • Fouse, S.D.1    Shen, Y.2    Pellegrini, M.3    Cole, S.4    Meissner, A.5
  • 29
    • 13844257513 scopus 로고    scopus 로고
    • DLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic development
    • Durkin ME, Avner MR, Huh CG, Yuan BZ, Thorgeirsson SS, et al. (2005) DLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic development. FEBS Lett 579: 1191-1196.
    • (2005) FEBS Lett , vol.579 , pp. 1191-1196
    • Durkin, M.E.1    Avner, M.R.2    Huh, C.G.3    Yuan, B.Z.4    Thorgeirsson, S.S.5
  • 31
    • 38449083769 scopus 로고    scopus 로고
    • Status of genomic imprinting in human embryonic stem cells as revealed by a large cohort of independently derived and maintained lines
    • Rugg-Gunn PJ, Ferguson-Smith AC, Pedersen RA (2007) Status of genomic imprinting in human embryonic stem cells as revealed by a large cohort of independently derived and maintained lines. Hum Mol Genet 16 Spec No. 2: R243-251.
    • (2007) Hum Mol Genet , vol.16 , Issue.SPEC 2
    • Rugg-Gunn, P.J.1    Ferguson-Smith, A.C.2    Pedersen, R.A.3
  • 33
    • 33646045010 scopus 로고    scopus 로고
    • Stem cells and cancer: Two faces of eve
    • Clarke MF, Fuller M (2006) Stem cells and cancer: two faces of eve. Cell 124: 1111-1115.
    • (2006) Cell , vol.124 , pp. 1111-1115
    • Clarke, M.F.1    Fuller, M.2
  • 35
    • 0038610795 scopus 로고    scopus 로고
    • Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis
    • Woolf E, Xiao C, Fainaru O, Lotem J, Rosen D, et al. (2003) Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis. Proc Natl Acad Sci U S A 100: 7731-7736.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7731-7736
    • Woolf, E.1    Xiao, C.2    Fainaru, O.3    Lotem, J.4    Rosen, D.5
  • 36
    • 34547744867 scopus 로고    scopus 로고
    • The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells
    • Egawa T, Tillman RE, Naoe Y, Taniuchi I, Littman DR (2007) The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells. J Exp Med 204: 1945-1957.
    • (2007) J Exp Med , vol.204 , pp. 1945-1957
    • Egawa, T.1    Tillman, R.E.2    Naoe, Y.3    Taniuchi, I.4    Littman, D.R.5
  • 37
    • 18444406568 scopus 로고    scopus 로고
    • The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons
    • Levanon D, Bettoun D, Harris-Cerruti C, Woolf E, Negreanu V, et al. (2002) The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons. Embo J 21: 3454-3463.
    • (2002) Embo J , vol.21 , pp. 3454-3463
    • Levanon, D.1    Bettoun, D.2    Harris-Cerruti, C.3    Woolf, E.4    Negreanu, V.5
  • 38
    • 34547102737 scopus 로고    scopus 로고
    • Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage
    • Pankratz MT, Li XJ, Lavaute TM, Lyons EA, Chen X, et al. (2007) Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage. Stem Cells 25: 1511-1520.
    • (2007) Stem Cells , vol.25 , pp. 1511-1520
    • Pankratz, M.T.1    Li, X.J.2    Lavaute, T.M.3    Lyons, E.A.4    Chen, X.5
  • 39
    • 20144388146 scopus 로고    scopus 로고
    • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
    • Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, et al. (2005) Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37: 391-400.
    • (2005) Nat Genet , vol.37 , pp. 391-400
    • Fraga, M.F.1    Ballestar, E.2    Villar-Garea, A.3    Boix-Chornet, M.4    Espada, J.5


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