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Volumn 637, Issue 1-2, 2008, Pages 1-15

Histone acetylation and chromatin signature in stem cell identity and cancer

Author keywords

Cancer; Chromatin modifications; Epigenetic mechanisms; Histone acetylation; Histone acetyltransferases; Stem and progenitor cells

Indexed keywords

DNA; HISTONE ACETYLTRANSFERASE;

EID: 37249012497     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2007.07.012     Document Type: Short Survey
Times cited : (72)

References (108)
  • 1
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • Feinberg A.P., Ohlsson R., and Henikoff S. The epigenetic progenitor origin of human cancer. Nat. Rev. Genet. 7 (2006) 21-33
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 2
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans M.J., and Kaufman M.H. Establishment in culture of pluripotential cells from mouse embryos. Nature 292 (1981) 154-156
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 4
    • 23944457397 scopus 로고    scopus 로고
    • Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
    • Cowan C.A., Atienza J., Melton D.A., and Eggan K. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309 (2005) 1369-1373
    • (2005) Science , vol.309 , pp. 1369-1373
    • Cowan, C.A.1    Atienza, J.2    Melton, D.A.3    Eggan, K.4
  • 5
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., and Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006) 663-676
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 7
    • 33644826473 scopus 로고    scopus 로고
    • Roots and stems: stem cells in cancer
    • Polyak K., and Hahn W.C. Roots and stems: stem cells in cancer. Nat. Med. 12 (2006) 296-300
    • (2006) Nat. Med. , vol.12 , pp. 296-300
    • Polyak, K.1    Hahn, W.C.2
  • 8
    • 85047690508 scopus 로고    scopus 로고
    • Opinion: the origin of the cancer stem cell: current controversies and new insights
    • Bjerkvig R., Tysnes B.B., Aboody K.S., Najbauer J., and Terzis A.J. Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat. Rev. Cancer 5 (2005) 899-904
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 899-904
    • Bjerkvig, R.1    Tysnes, B.B.2    Aboody, K.S.3    Najbauer, J.4    Terzis, A.J.5
  • 9
    • 33845755946 scopus 로고    scopus 로고
    • Heterochromatin revisited
    • Grewal S.I., and Jia S. Heterochromatin revisited. Nat. Rev. Genet. 8 (2007) 35-46
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 35-46
    • Grewal, S.I.1    Jia, S.2
  • 10
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., and Allis C.D. Translating the histone code. Science 293 (2001) 1074-1080
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 12
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl B.D., and Allis C.D. The language of covalent histone modifications. Nature 403 (2000) 41-45
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 13
    • 0035822999 scopus 로고    scopus 로고
    • The many faces of chromatin remodeling: switching beyond transcription
    • Fyodorov D.V., and Kadonaga J.T. The many faces of chromatin remodeling: switching beyond transcription. Cell 106 (2001) 523-525
    • (2001) Cell , vol.106 , pp. 523-525
    • Fyodorov, D.V.1    Kadonaga, J.T.2
  • 14
    • 0038204415 scopus 로고    scopus 로고
    • The diverse functions of histone acetyltransferase complexes
    • Carrozza M.J., Utley R.T., Workman J.L., and Cote J. The diverse functions of histone acetyltransferase complexes. Trends Genet. 19 (2003) 321-329
    • (2003) Trends Genet. , vol.19 , pp. 321-329
    • Carrozza, M.J.1    Utley, R.T.2    Workman, J.L.3    Cote, J.4
  • 15
    • 27544505676 scopus 로고    scopus 로고
    • Chromatin modifier enzymes, the histone code and cancer
    • Santos-Rosa H., and Caldas C. Chromatin modifier enzymes, the histone code and cancer. Eur. J. Cancer 41 (2005) 2381-2402
    • (2005) Eur. J. Cancer , vol.41 , pp. 2381-2402
    • Santos-Rosa, H.1    Caldas, C.2
  • 17
    • 0034051227 scopus 로고    scopus 로고
    • Acetylation of histones and transcription-related factors
    • Sterner D.E., and Berger S.L. Acetylation of histones and transcription-related factors. Microbiol. Mol. Biol. Rev. 64 (2000) 435-459
    • (2000) Microbiol. Mol. Biol. Rev. , vol.64 , pp. 435-459
    • Sterner, D.E.1    Berger, S.L.2
  • 18
    • 0029984469 scopus 로고    scopus 로고
    • Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation
    • Brownell J.E., Zhou J., Ranalli T., Kobayashi R., Edmondson D.G., Roth S.Y., and Allis C.D. Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84 (1996) 843-851
    • (1996) Cell , vol.84 , pp. 843-851
    • Brownell, J.E.1    Zhou, J.2    Ranalli, T.3    Kobayashi, R.4    Edmondson, D.G.5    Roth, S.Y.6    Allis, C.D.7
  • 19
    • 0029665857 scopus 로고    scopus 로고
    • A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
    • Yang X.J., Ogryzko V.V., Nishikawa J., Howard B.H., and Nakatani Y. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382 (1996) 319-324
    • (1996) Nature , vol.382 , pp. 319-324
    • Yang, X.J.1    Ogryzko, V.V.2    Nishikawa, J.3    Howard, B.H.4    Nakatani, Y.5
  • 20
    • 0030606239 scopus 로고    scopus 로고
    • The transcriptional coactivators p300 and CBP are histone acetyltransferases
    • Ogryzko V.V., Schiltz R.L., Russanova V., Howard B.H., and Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87 (1996) 953-959
    • (1996) Cell , vol.87 , pp. 953-959
    • Ogryzko, V.V.1    Schiltz, R.L.2    Russanova, V.3    Howard, B.H.4    Nakatani, Y.5
  • 21
    • 0030480969 scopus 로고    scopus 로고
    • The CBP co-activator is a histone acetyltransferase
    • Bannister A.J., and Kouzarides T. The CBP co-activator is a histone acetyltransferase. Nature 384 (1996) 641-643
    • (1996) Nature , vol.384 , pp. 641-643
    • Bannister, A.J.1    Kouzarides, T.2
  • 23
    • 2342599619 scopus 로고    scopus 로고
    • The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases
    • Yang X.J. The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Nucl. Acids Res. 32 (2004) 959-976
    • (2004) Nucl. Acids Res. , vol.32 , pp. 959-976
    • Yang, X.J.1
  • 25
    • 0034234237 scopus 로고    scopus 로고
    • CBP/p300 in cell growth, transformation, and development
    • Goodman R.H., and Smolik S. CBP/p300 in cell growth, transformation, and development. Genes Dev. 14 (2000) 1553-1577
    • (2000) Genes Dev. , vol.14 , pp. 1553-1577
    • Goodman, R.H.1    Smolik, S.2
  • 27
    • 0037015044 scopus 로고    scopus 로고
    • SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription
    • Sterner D.E., Belotserkovskaya R., and Berger S.L. SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription. Proc. Natl. Acad. Sci. USA 99 (2002) 11622-11627
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 11622-11627
    • Sterner, D.E.1    Belotserkovskaya, R.2    Berger, S.L.3
  • 29
    • 0035883954 scopus 로고    scopus 로고
    • Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
    • Zhang Y., and Reinberg D. Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev. 15 (2001) 2343-2360
    • (2001) Genes Dev. , vol.15 , pp. 2343-2360
    • Zhang, Y.1    Reinberg, D.2
  • 30
    • 33644853802 scopus 로고    scopus 로고
    • Histone modifications: signalling receptors and potential elements of a heritable epigenetic code
    • Nightingale K.P., O'Neill L.P., and Turner B.M. Histone modifications: signalling receptors and potential elements of a heritable epigenetic code. Curr. Opin. Genet Dev. 16 (2006) 125-136
    • (2006) Curr. Opin. Genet Dev. , vol.16 , pp. 125-136
    • Nightingale, K.P.1    O'Neill, L.P.2    Turner, B.M.3
  • 31
    • 25444480573 scopus 로고    scopus 로고
    • Rendez-vous at mitosis: TRRAPed in the chromatin
    • Herceg Z., and Wang Z.Q. Rendez-vous at mitosis: TRRAPed in the chromatin. Cell Cycle 4 (2005) 383-387
    • (2005) Cell Cycle , vol.4 , pp. 383-387
    • Herceg, Z.1    Wang, Z.Q.2
  • 32
  • 33
    • 0036847620 scopus 로고    scopus 로고
    • Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes
    • Hassan A.H., Prochasson P., Neely K.E., Galasinski S.C., Chandy M., Carrozza M.J., and Workman J.L. Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes. Cell 111 (2002) 369-379
    • (2002) Cell , vol.111 , pp. 369-379
    • Hassan, A.H.1    Prochasson, P.2    Neely, K.E.3    Galasinski, S.C.4    Chandy, M.5    Carrozza, M.J.6    Workman, J.L.7
  • 36
    • 0026580006 scopus 로고
    • brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2
    • Tamkun J.W., Deuring R., Scott M.P., Kissinger M., Pattatucci A.M., Kaufman T.C., and Kennison J.A. brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68 (1992) 561-572
    • (1992) Cell , vol.68 , pp. 561-572
    • Tamkun, J.W.1    Deuring, R.2    Scott, M.P.3    Kissinger, M.4    Pattatucci, A.M.5    Kaufman, T.C.6    Kennison, J.A.7
  • 37
    • 0035432099 scopus 로고    scopus 로고
    • The bromodomain: a regulator of ATP-dependent chromatin remodeling?
    • Horn P.J., and Peterson C.L. The bromodomain: a regulator of ATP-dependent chromatin remodeling?. Front Biosci. 6 (2001) D1019-D1023
    • (2001) Front Biosci. , vol.6
    • Horn, P.J.1    Peterson, C.L.2
  • 38
    • 17444386662 scopus 로고    scopus 로고
    • The bromodomain: a chromatin-targeting module?
    • Winston F., and Allis C.D. The bromodomain: a chromatin-targeting module?. Nat. Struct. Biol. 6 (1999) 601-604
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 601-604
    • Winston, F.1    Allis, C.D.2
  • 39
    • 2942519726 scopus 로고    scopus 로고
    • Structures of protein domains that create or recognize histone modifications
    • Bottomley M.J. Structures of protein domains that create or recognize histone modifications. EMBO Rep. 5 (2004) 464-469
    • (2004) EMBO Rep. , vol.5 , pp. 464-469
    • Bottomley, M.J.1
  • 40
    • 0034669210 scopus 로고    scopus 로고
    • The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p
    • Owen D.J., Ornaghi P., Yang J.C., Lowe N., Evans P.R., Ballario P., Neuhaus D., Filetici P., and Travers A.A. The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p. EMBO J. 19 (2000) 6141-6149
    • (2000) EMBO J. , vol.19 , pp. 6141-6149
    • Owen, D.J.1    Ornaghi, P.2    Yang, J.C.3    Lowe, N.4    Evans, P.R.5    Ballario, P.6    Neuhaus, D.7    Filetici, P.8    Travers, A.A.9
  • 41
    • 0034717183 scopus 로고    scopus 로고
    • Structure and function of a human TAFII250 double bromodomain module
    • Jacobson R.H., Ladurner A.G., King D.S., and Tjian R. Structure and function of a human TAFII250 double bromodomain module. Science 288 (2000) 1422-1425
    • (2000) Science , vol.288 , pp. 1422-1425
    • Jacobson, R.H.1    Ladurner, A.G.2    King, D.S.3    Tjian, R.4
  • 42
    • 0035827534 scopus 로고    scopus 로고
    • Targeted and extended acetylation of histones H4 and H3 at active and inactive genes in chicken embryo erythrocytes
    • Myers F.A., Evans D.R., Clayton A.L., Thorne A.W., and Crane-Robinson C. Targeted and extended acetylation of histones H4 and H3 at active and inactive genes in chicken embryo erythrocytes. J. Biol. Chem. 276 (2001) 20197-20205
    • (2001) J. Biol. Chem. , vol.276 , pp. 20197-20205
    • Myers, F.A.1    Evans, D.R.2    Clayton, A.L.3    Thorne, A.W.4    Crane-Robinson, C.5
  • 43
    • 20444443164 scopus 로고    scopus 로고
    • Hyperacetylated chromatin domains: lessons from heterochromatin
    • Bulger M. Hyperacetylated chromatin domains: lessons from heterochromatin. J. Biol. Chem. 280 (2005) 21689-21692
    • (2005) J. Biol. Chem. , vol.280 , pp. 21689-21692
    • Bulger, M.1
  • 44
    • 0034707037 scopus 로고    scopus 로고
    • Global histone acetylation and deacetylation in yeast
    • Vogelauer M., Wu J., Suka N., and Grunstein M. Global histone acetylation and deacetylation in yeast. Nature 408 (2000) 495-498
    • (2000) Nature , vol.408 , pp. 495-498
    • Vogelauer, M.1    Wu, J.2    Suka, N.3    Grunstein, M.4
  • 45
    • 12844264053 scopus 로고    scopus 로고
    • Heterochromatin, position effects, and the genetic dissection of chromatin
    • Eissenberg J.C., and Wallrath L.L. Heterochromatin, position effects, and the genetic dissection of chromatin. Prog. Nucl. Acid Res. Mol Biol. 74 (2003) 275-299
    • (2003) Prog. Nucl. Acid Res. Mol Biol. , vol.74 , pp. 275-299
    • Eissenberg, J.C.1    Wallrath, L.L.2
  • 46
    • 0037636027 scopus 로고    scopus 로고
    • The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae
    • Rusche L.N., Kirchmaier A.L., and Rine J. The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. Annu. Rev. Biochem. 72 (2003) 481-516
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 481-516
    • Rusche, L.N.1    Kirchmaier, A.L.2    Rine, J.3
  • 47
    • 0028326787 scopus 로고
    • Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain
    • Hebbes T.R., Clayton A.L., Thorne A.W., and Crane-Robinson C. Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain. EMBO J. 13 (1994) 1823-1830
    • (1994) EMBO J. , vol.13 , pp. 1823-1830
    • Hebbes, T.R.1    Clayton, A.L.2    Thorne, A.W.3    Crane-Robinson, C.4
  • 48
    • 0035341465 scopus 로고    scopus 로고
    • Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci
    • Litt M.D., Simpson M., Recillas-Targa F., Prioleau M.N., and Felsenfeld G. Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci. EMBO J. 20 (2001) 2224-2235
    • (2001) EMBO J. , vol.20 , pp. 2224-2235
    • Litt, M.D.1    Simpson, M.2    Recillas-Targa, F.3    Prioleau, M.N.4    Felsenfeld, G.5
  • 50
    • 0042091987 scopus 로고    scopus 로고
    • A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus
    • Bulger M., Schubeler D., Bender M.A., Hamilton J., Farrell C.M., Hardison R.C., and Groudine M. A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus. Mol. Cell Biol. 23 (2003) 5234-5244
    • (2003) Mol. Cell Biol. , vol.23 , pp. 5234-5244
    • Bulger, M.1    Schubeler, D.2    Bender, M.A.3    Hamilton, J.4    Farrell, C.M.5    Hardison, R.C.6    Groudine, M.7
  • 51
    • 0035949586 scopus 로고    scopus 로고
    • The murine beta-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes
    • Schubeler D., Groudine M., and Bender M.A. The murine beta-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes. Proc. Natl. Acad. Sci. USA 98 (2001) 11432-11437
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11432-11437
    • Schubeler, D.1    Groudine, M.2    Bender, M.A.3
  • 52
    • 0035834059 scopus 로고    scopus 로고
    • Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster
    • Anguita E., Johnson C.A., Wood W.G., Turner B.M., and Higgs D.R. Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster. Proc. Natl. Acad. Sci. USA 98 (2001) 12114-12119
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12114-12119
    • Anguita, E.1    Johnson, C.A.2    Wood, W.G.3    Turner, B.M.4    Higgs, D.R.5
  • 54
    • 0035890244 scopus 로고    scopus 로고
    • Stepwise activation of the immunoglobulin mu heavy chain gene locus
    • Chowdhury D., and Sen R. Stepwise activation of the immunoglobulin mu heavy chain gene locus. EMBO J. 20 (2001) 6394-6403
    • (2001) EMBO J. , vol.20 , pp. 6394-6403
    • Chowdhury, D.1    Sen, R.2
  • 55
    • 0037320461 scopus 로고    scopus 로고
    • Chromatin remodeling and extragenic transcription at the MHC class II locus control region
    • Masternak K., Peyraud N., Krawczyk M., Barras E., and Reith W. Chromatin remodeling and extragenic transcription at the MHC class II locus control region. Nat. Immunol. 4 (2003) 132-137
    • (2003) Nat. Immunol. , vol.4 , pp. 132-137
    • Masternak, K.1    Peyraud, N.2    Krawczyk, M.3    Barras, E.4    Reith, W.5
  • 57
    • 0018374782 scopus 로고
    • Emil Heitz and the concept of heterochromatin: longitudinal chromosome differentiation was recognized fifty years ago
    • Passarge E. Emil Heitz and the concept of heterochromatin: longitudinal chromosome differentiation was recognized fifty years ago. Am. J. Hum. Genet. 31 (1979) 106-115
    • (1979) Am. J. Hum. Genet. , vol.31 , pp. 106-115
    • Passarge, E.1
  • 58
    • 33846535507 scopus 로고    scopus 로고
    • Cell biology: chromosome territories
    • Meaburn K.J., and Misteli T. Cell biology: chromosome territories. Nature 445 (2007) 379-781
    • (2007) Nature , vol.445 , pp. 379-781
    • Meaburn, K.J.1    Misteli, T.2
  • 59
    • 10044244766 scopus 로고    scopus 로고
    • Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila
    • Ebert A., Schotta G., Lein S., Kubicek S., Krauss V., Jenuwein T., and Reuter G. Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev. 18 (2004) 2973-2983
    • (2004) Genes Dev. , vol.18 , pp. 2973-2983
    • Ebert, A.1    Schotta, G.2    Lein, S.3    Kubicek, S.4    Krauss, V.5    Jenuwein, T.6    Reuter, G.7
  • 60
    • 33644626412 scopus 로고    scopus 로고
    • Heterochromatin assembly: a new twist on an old model
    • Horn P.J., and Peterson C.L. Heterochromatin assembly: a new twist on an old model. Chromosome Res. 14 (2006) 83-94
    • (2006) Chromosome Res. , vol.14 , pp. 83-94
    • Horn, P.J.1    Peterson, C.L.2
  • 65
    • 0036863542 scopus 로고    scopus 로고
    • Histone acetylation regulates the time of replication origin firing
    • Vogelauer M., Rubbi L., Lucas I., Brewer B.J., and Grunstein M. Histone acetylation regulates the time of replication origin firing. Mol. Cell 10 (2002) 1223-1233
    • (2002) Mol. Cell , vol.10 , pp. 1223-1233
    • Vogelauer, M.1    Rubbi, L.2    Lucas, I.3    Brewer, B.J.4    Grunstein, M.5
  • 67
    • 0037078986 scopus 로고    scopus 로고
    • Establishment of transcriptional competence in early and late S phase
    • Zhang J., Xu F., Hashimshony T., Keshet I., and Cedar H. Establishment of transcriptional competence in early and late S phase. Nature 420 (2002) 198-202
    • (2002) Nature , vol.420 , pp. 198-202
    • Zhang, J.1    Xu, F.2    Hashimshony, T.3    Keshet, I.4    Cedar, H.5
  • 68
    • 33846184752 scopus 로고    scopus 로고
    • Nanog and transcriptional networks in embryonic stem cell pluripotency
    • Pan G., and Thomson J.A. Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res. 17 (2007) 42-49
    • (2007) Cell Res. , vol.17 , pp. 42-49
    • Pan, G.1    Thomson, J.A.2
  • 69
    • 33747614295 scopus 로고    scopus 로고
    • Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
    • Xiao L., Yuan X., and Sharkis S.J. Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Stem Cells 24 (2006) 1476-1486
    • (2006) Stem Cells , vol.24 , pp. 1476-1486
    • Xiao, L.1    Yuan, X.2    Sharkis, S.J.3
  • 71
    • 2942746179 scopus 로고    scopus 로고
    • Histone variants, nucleosome assembly and epigenetic inheritance
    • Henikoff S., Furuyama T., and Ahmad K. Histone variants, nucleosome assembly and epigenetic inheritance. Trends Genet. 20 (2004) 320-326
    • (2004) Trends Genet. , vol.20 , pp. 320-326
    • Henikoff, S.1    Furuyama, T.2    Ahmad, K.3
  • 72
    • 20444391346 scopus 로고    scopus 로고
    • Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair
    • Thiriet C., and Hayes J.J. Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair. Mol. Cell 18 (2005) 617-622
    • (2005) Mol. Cell , vol.18 , pp. 617-622
    • Thiriet, C.1    Hayes, J.J.2
  • 73
    • 3042760021 scopus 로고    scopus 로고
    • Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins
    • Phair R.D., Scaffidi P., Elbi C., Vecerova J., Dey A., Ozato K., Brown D.T., Hager G., Bustin M., and Misteli T. Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol. Cell Biol. 24 (2004) 6393-6402
    • (2004) Mol. Cell Biol. , vol.24 , pp. 6393-6402
    • Phair, R.D.1    Scaffidi, P.2    Elbi, C.3    Vecerova, J.4    Dey, A.5    Ozato, K.6    Brown, D.T.7    Hager, G.8    Bustin, M.9    Misteli, T.10
  • 77
    • 1042302747 scopus 로고    scopus 로고
    • Histone deacetylase activity is required for embryonic stem cell differentiation
    • Lee J.H., Hart S.R., and Skalnik D.G. Histone deacetylase activity is required for embryonic stem cell differentiation. Genesis 38 (2004) 32-38
    • (2004) Genesis , vol.38 , pp. 32-38
    • Lee, J.H.1    Hart, S.R.2    Skalnik, D.G.3
  • 81
    • 8844265508 scopus 로고    scopus 로고
    • Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
    • Ringrose L., and Paro R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu. Rev. Genet. 38 (2004) 413-443
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 413-443
    • Ringrose, L.1    Paro, R.2
  • 83
    • 1942503942 scopus 로고    scopus 로고
    • The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
    • Cao R., and Zhang Y. The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr. Opin. Genet. Dev. 14 (2004) 155-164
    • (2004) Curr. Opin. Genet. Dev. , vol.14 , pp. 155-164
    • Cao, R.1    Zhang, Y.2
  • 84
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor T.H. The DNA methyltransferases of mammals. Hum. Mol. Genet. 9 (2000) 2395-2402
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2395-2402
    • Bestor, T.H.1
  • 86
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3 (2002) 415-428
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 87
    • 0034790436 scopus 로고    scopus 로고
    • Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression
    • Herceg Z., Hulla W., Gell D., Cuenin C., Lleonart M., Jackson S., and Wang Z.Q. Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression. Nat. Genet. 29 (2001) 206-211
    • (2001) Nat. Genet. , vol.29 , pp. 206-211
    • Herceg, Z.1    Hulla, W.2    Gell, D.3    Cuenin, C.4    Lleonart, M.5    Jackson, S.6    Wang, Z.Q.7
  • 89
    • 0032493894 scopus 로고    scopus 로고
    • The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins
    • McMahon S.B., Van Buskirk H.A., Dugan K.A., Copeland T.D., and Cole M.D. The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94 (1998) 363-374
    • (1998) Cell , vol.94 , pp. 363-374
    • McMahon, S.B.1    Van Buskirk, H.A.2    Dugan, K.A.3    Copeland, T.D.4    Cole, M.D.5
  • 92
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • Sparmann A., and van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat. Rev. Cancer 6 (2006) 846-856
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 846-856
    • Sparmann, A.1    van Lohuizen, M.2
  • 93
    • 0033567954 scopus 로고    scopus 로고
    • NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p
    • Allard S., Utley R.T., Savard J., Clarke A., Grant P., Brandl C.J., Pillus L., Workman J.L., and Cote J. NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p. EMBO J. 18 (1999) 5108-5119
    • (1999) EMBO J. , vol.18 , pp. 5108-5119
    • Allard, S.1    Utley, R.T.2    Savard, J.3    Clarke, A.4    Grant, P.5    Brandl, C.J.6    Pillus, L.7    Workman, J.L.8    Cote, J.9
  • 97
    • 1342346531 scopus 로고    scopus 로고
    • Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans
    • Doyon Y., Selleck W., Lane W.S., Tan S., and Cote J. Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Mol. Cell Biol. 24 (2004) 1884-1896
    • (2004) Mol. Cell Biol. , vol.24 , pp. 1884-1896
    • Doyon, Y.1    Selleck, W.2    Lane, W.S.3    Tan, S.4    Cote, J.5
  • 98
    • 1842583739 scopus 로고    scopus 로고
    • A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling
    • Ceol C.J., and Horvitz H.R. A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling. Dev. Cell 6 (2004) 563-576
    • (2004) Dev. Cell , vol.6 , pp. 563-576
    • Ceol, C.J.1    Horvitz, H.R.2
  • 99
    • 33644646401 scopus 로고    scopus 로고
    • Chemoprotection by sulforaphane: keep one eye beyond Keap1
    • Myzak M.C., and Dashwood R.H. Chemoprotection by sulforaphane: keep one eye beyond Keap1. Cancer Lett. 233 (2006) 208-218
    • (2006) Cancer Lett. , vol.233 , pp. 208-218
    • Myzak, M.C.1    Dashwood, R.H.2
  • 100
    • 2942724589 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: development as cancer therapy
    • discussion 281-268
    • Marks P.A., Richon V.M., Kelly W.K., Chiao J.H., and Miller T. Histone deacetylase inhibitors: development as cancer therapy. Novartis Found Symp. 259 (2004) 269-281 discussion 281-268
    • (2004) Novartis Found Symp. , vol.259 , pp. 269-281
    • Marks, P.A.1    Richon, V.M.2    Kelly, W.K.3    Chiao, J.H.4    Miller, T.5
  • 103
    • 0035525781 scopus 로고    scopus 로고
    • Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report
    • Piekarz R.L., Robey R., Sandor V., Bakke S., Wilson W.H., Dahmoush L., Kingma D.M., Turner M.L., Altemus R., and Bates S.E. Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report. Blood 98 (2001) 2865-2868
    • (2001) Blood , vol.98 , pp. 2865-2868
    • Piekarz, R.L.1    Robey, R.2    Sandor, V.3    Bakke, S.4    Wilson, W.H.5    Dahmoush, L.6    Kingma, D.M.7    Turner, M.L.8    Altemus, R.9    Bates, S.E.10
  • 104
    • 31344466008 scopus 로고    scopus 로고
    • DNA methylation and gene silencing in cancer
    • Baylin S.B. DNA methylation and gene silencing in cancer. Nat. Clin. Pract. Oncol. 2 Suppl. 1 (2005) S4-S11
    • (2005) Nat. Clin. Pract. Oncol. , vol.2 , Issue.SUPPL. 1
    • Baylin, S.B.1
  • 105
    • 0141502199 scopus 로고    scopus 로고
    • Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia
    • Christiansen D.H., Andersen M.K., and Pedersen-Bjergaard J. Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 17 (2003) 1813-1819
    • (2003) Leukemia , vol.17 , pp. 1813-1819
    • Christiansen, D.H.1    Andersen, M.K.2    Pedersen-Bjergaard, J.3
  • 106
    • 0037108309 scopus 로고    scopus 로고
    • Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-aza-2′-deoxycytidine (decitabine) treatment
    • Daskalakis M., Nguyen T.T., Nguyen C., Guldberg P., Kohler G., Wijermans P., Jones P.A., and Lubbert M. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-aza-2′-deoxycytidine (decitabine) treatment. Blood 100 (2002) 2957-2964
    • (2002) Blood , vol.100 , pp. 2957-2964
    • Daskalakis, M.1    Nguyen, T.T.2    Nguyen, C.3    Guldberg, P.4    Kohler, G.5    Wijermans, P.6    Jones, P.A.7    Lubbert, M.8
  • 107
    • 0034105545 scopus 로고    scopus 로고
    • DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action
    • Lubbert M. DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action. Curr. Top Microbiol. Immunol. 249 (2000) 135-164
    • (2000) Curr. Top Microbiol. Immunol. , vol.249 , pp. 135-164
    • Lubbert, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.