메뉴 건너뛰기




Volumn 15, Issue 8, 2011, Pages

Recent advances in leishmaniasis treatment

Author keywords

Chemotherapeutics; Drug delivery systems; Leishmaniasis treatment

Indexed keywords

2 [(2,4 DICHLORO 5 METHYLPHENYL)SULFANYL] 1,3 DINITRO 5 (TRIFLUOROMETHYL BENZENE); 4 BUTOXYPHENYL) N' [2 [(7 CHLOROQUINOLIN 4 YL)AM INO]ETHYL]UREA; AMIDE; AMPHOTERICIN B; AMPHOTERICIN B CHOLESTEROL SULFATE; AMPHOTERICIN B LIPID COMPLEX; ANNONA CORIACEA EXTRACT; ANTILEISHMANIAL AGENT; ANTIMONY DERIVATIVE; BACCHARIS DRACUNCULIFOLIA EXTRACT; DYSOXYLUM BINECTARIFERUM EXTRACT; EDELFOSINE; FERULA SZOWITSIANA EXTRACT; GOUANIA LUPULOIDES EXTRACT; ILMOFOSINE; LIPID TRANSFER PROTEIN; LIPOSOME; MEGLUMINE ANTIMONATE; MILTEFOSINE; NANOPARTICLE; PAGIANTHA CERIFERA EXTRACT; PAROMOMYCIN; PENTAMIDINE; PERIFOSINE; PLANT EXTRACT; PYRIMIDINE DERIVATIVE; SCROPHULARIA CRYPTOPHILA EXTRACT; SITAMAQUINE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 79961029192     PISSN: 12019712     EISSN: 18783511     Source Type: Journal    
DOI: 10.1016/j.ijid.2011.03.021     Document Type: Review
Times cited : (296)

References (119)
  • 1
    • 3042555141 scopus 로고    scopus 로고
    • Leishmaniasis: current situation and new perspectives
    • Desjeux P. Leishmaniasis: current situation and new perspectives. Comp Immunol Microbiol Infect Dis 2004, 27:305-318.
    • (2004) Comp Immunol Microbiol Infect Dis , vol.27 , pp. 305-318
    • Desjeux, P.1
  • 5
    • 33746825106 scopus 로고    scopus 로고
    • Phlebotomine sand flies and Leishmania parasites: friends or foes?
    • Kamhawi S. Phlebotomine sand flies and Leishmania parasites: friends or foes?. Trends Parasitol 2006, 22:439-445.
    • (2006) Trends Parasitol , vol.22 , pp. 439-445
    • Kamhawi, S.1
  • 6
    • 0034825692 scopus 로고    scopus 로고
    • Life in vacuoles-nutrient acquisition by Leishmania amastigotes
    • Burchmore R.J., Barrett M.P. Life in vacuoles-nutrient acquisition by Leishmania amastigotes. Int J Parasitol 2001, 31:1311-1320.
    • (2001) Int J Parasitol , vol.31 , pp. 1311-1320
    • Burchmore, R.J.1    Barrett, M.P.2
  • 7
    • 0033774142 scopus 로고    scopus 로고
    • Cutaneous leishmaniasis
    • Hepburn N.C. Cutaneous leishmaniasis. Clin Exp Dermatol 2000, 25:363-370.
    • (2000) Clin Exp Dermatol , vol.25 , pp. 363-370
    • Hepburn, N.C.1
  • 8
    • 84873089209 scopus 로고    scopus 로고
    • World Health Organization. Visceral leishmaniasis therapy: statement on the outcome of a meeting. Geneva: WHO;. Available at: (accessed August 16, 2010).
    • World Health Organization. Visceral leishmaniasis therapy: statement on the outcome of a meeting. Geneva: WHO; 2009. Available at: (accessed August 16, 2010). http://www.who.int/leishmaniasis/resources/Leish_VL_Therapy_statement.pdf.
    • (2009)
  • 9
    • 74049122035 scopus 로고    scopus 로고
    • Drug resistance in visceral leishmaniasis
    • Maltezou H.C. Drug resistance in visceral leishmaniasis. J Biomed Biotechnol 2010, 2010:617521.
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 617521
    • Maltezou, H.C.1
  • 10
    • 84873096354 scopus 로고    scopus 로고
    • World Health Organization. Leishmaniasis: magnitude of the problem. Geneva: WHO;. Available at: (accessed November 30, 2010).
    • World Health Organization. Leishmaniasis: magnitude of the problem. Geneva: WHO; 2009. Available at: (accessed November 30, 2010). http://www.who.int/leishmaniasis/burden/magnitude/burden_magnitude/en/index.html.
    • (2009)
  • 11
    • 34548456082 scopus 로고    scopus 로고
    • The leishmaniases-survival and expansion in a changing world
    • Shaw J. The leishmaniases-survival and expansion in a changing world. Mem Inst Oswaldo Cruz 2007, 102:541-547.
    • (2007) Mem Inst Oswaldo Cruz , vol.102 , pp. 541-547
    • Shaw, J.1
  • 12
    • 1642565137 scopus 로고    scopus 로고
    • Visceral leishmaniasis in immunocompromised patients with and without AIDS: a comparison of clinical features and prognosis
    • Fernández-Guerrero M.L., Robles P., Rivas P., Mójer F., Muñíz G., Górgolas M. Visceral leishmaniasis in immunocompromised patients with and without AIDS: a comparison of clinical features and prognosis. Acta Trop 2004, 90:11-16.
    • (2004) Acta Trop , vol.90 , pp. 11-16
    • Fernández-Guerrero, M.L.1    Robles, P.2    Rivas, P.3    Mójer, F.4    Muñíz, G.5    Górgolas, M.6
  • 13
    • 70350571813 scopus 로고    scopus 로고
    • Atypical disseminated leishmaniasis similar to post-kala-azar dermal leishmaniasis in a Brazilian AIDS patient infected with Leishmania (Leishmania) infantum chagasi: a case report
    • Carnaúba D., Konishi C.T., Petri V., Martinez I.C.P., Shimizu L., Pereira-Chioccola V.L. Atypical disseminated leishmaniasis similar to post-kala-azar dermal leishmaniasis in a Brazilian AIDS patient infected with Leishmania (Leishmania) infantum chagasi: a case report. Int J Infect Dis 2009, 13:504-507.
    • (2009) Int J Infect Dis , vol.13 , pp. 504-507
    • Carnaúba, D.1    Konishi, C.T.2    Petri, V.3    Martinez, I.C.P.4    Shimizu, L.5    Pereira-Chioccola, V.L.6
  • 14
    • 26844461073 scopus 로고    scopus 로고
    • Chemotherapy of trypanosomiases and leishmaniasis
    • Croft S.L., Barret M.P., Urbina J.A. Chemotherapy of trypanosomiases and leishmaniasis. Trends Parasitol 2005, 21:508-512.
    • (2005) Trends Parasitol , vol.21 , pp. 508-512
    • Croft, S.L.1    Barret, M.P.2    Urbina, J.A.3
  • 17
    • 0033517487 scopus 로고    scopus 로고
    • Leishmaniasis
    • Herwaldt B.L. Leishmaniasis. Lancet 1999, 2:1191-1199.
    • (1999) Lancet , vol.2 , pp. 1191-1199
    • Herwaldt, B.L.1
  • 18
    • 71549146250 scopus 로고    scopus 로고
    • Development of immunization strategies against leishmaniosis based on the Leishmania histones pathoantigens
    • Carrión J., Folgueira C., Alonso C. Development of immunization strategies against leishmaniosis based on the Leishmania histones pathoantigens. Procedia Vaccinol 2009, 1:101-103.
    • (2009) Procedia Vaccinol , vol.1 , pp. 101-103
    • Carrión, J.1    Folgueira, C.2    Alonso, C.3
  • 19
    • 37249030565 scopus 로고    scopus 로고
    • Mucosal leishmaniasis. Current scenario and prospects for treatment
    • Amato V.S., Tuon F.F., Bacha H.A., Neto V.A., Nicodemo A.C. Mucosal leishmaniasis. Current scenario and prospects for treatment. Acta Trop 2008, 105:1-9.
    • (2008) Acta Trop , vol.105 , pp. 1-9
    • Amato, V.S.1    Tuon, F.F.2    Bacha, H.A.3    Neto, V.A.4    Nicodemo, A.C.5
  • 20
    • 34249885063 scopus 로고    scopus 로고
    • Influence of Leishmania (Viannia) species on the response to antimonial treatment in patients with American tegumentary leishmaniasis
    • Arevalo J., Ramirez L., Adaui V., Zimic M., Tulliano G., Miranda-Verástegui C., et al. Influence of Leishmania (Viannia) species on the response to antimonial treatment in patients with American tegumentary leishmaniasis. J Infect Dis 2007, 195:1846-1851.
    • (2007) J Infect Dis , vol.195 , pp. 1846-1851
    • Arevalo, J.1    Ramirez, L.2    Adaui, V.3    Zimic, M.4    Tulliano, G.5    Miranda-Verástegui, C.6
  • 21
    • 84873091605 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention (CDC). Parasites-leishmaniasis. Resources for health professionals. Atlanta, GA: CDC;. Available at: (accessed December 2, 2010).
    • Centers for Disease Control and Prevention (CDC). Parasites-leishmaniasis. Resources for health professionals. Atlanta, GA: CDC; 2010. Available at: (accessed December 2, 2010). http://www.cdc.gov/parasites/leishmaniasis/health_professionals/index.html.
    • (2010)
  • 22
    • 7944237421 scopus 로고    scopus 로고
    • Leishmaniasis: drugs in the clinic, resistance and new developments
    • Ouellette M., Drummelsmith J., Papadopoulou B. Leishmaniasis: drugs in the clinic, resistance and new developments. Drug Resist Updat 2004, 7:257-266.
    • (2004) Drug Resist Updat , vol.7 , pp. 257-266
    • Ouellette, M.1    Drummelsmith, J.2    Papadopoulou, B.3
  • 23
    • 0142258171 scopus 로고    scopus 로고
    • Leishmaniasis-current chemotherapy and recent advances in the search for novel drugs
    • Croft S.L., Coombs G.H. Leishmaniasis-current chemotherapy and recent advances in the search for novel drugs. Trends Parasitol 2003, 19:502-508.
    • (2003) Trends Parasitol , vol.19 , pp. 502-508
    • Croft, S.L.1    Coombs, G.H.2
  • 24
    • 0033980453 scopus 로고    scopus 로고
    • A comparison of the activities of three amphotericin B lipid formulations against experimental visceral and cutaneous leishmaniasis
    • Yardley V., Croft S.L. A comparison of the activities of three amphotericin B lipid formulations against experimental visceral and cutaneous leishmaniasis. Int J Antimicrob Agents 2000, 13:243-248.
    • (2000) Int J Antimicrob Agents , vol.13 , pp. 243-248
    • Yardley, V.1    Croft, S.L.2
  • 26
    • 33749338420 scopus 로고    scopus 로고
    • Development of miltefosine as an oral treatment for leishmaniasis
    • Sindermann H., Engel J. Development of miltefosine as an oral treatment for leishmaniasis. Trans R Soc Trop Med Hyg 2006, 100:17-20.
    • (2006) Trans R Soc Trop Med Hyg , vol.100 , pp. 17-20
    • Sindermann, H.1    Engel, J.2
  • 27
    • 33749330723 scopus 로고    scopus 로고
    • Miltefosine-discovery of the antileishmanial activity of phospholipid derivatives
    • Croft S.L., Engel J. Miltefosine-discovery of the antileishmanial activity of phospholipid derivatives. Trans R Soc Trop Med Hyg 2006, 100:4-8.
    • (2006) Trans R Soc Trop Med Hyg , vol.100 , pp. 4-8
    • Croft, S.L.1    Engel, J.2
  • 30
    • 18944370727 scopus 로고    scopus 로고
    • Availability of miltefosine for the treatment of kala-azar in India
    • Sundar S., Murray H.W. Availability of miltefosine for the treatment of kala-azar in India. Bull World Health Organ 2005, 83:394-395.
    • (2005) Bull World Health Organ , vol.83 , pp. 394-395
    • Sundar, S.1    Murray, H.W.2
  • 31
    • 36448953526 scopus 로고    scopus 로고
    • Miltefosine in the treatment of leishmaniasis: clinical evidence for informed clinical risk management
    • Sundar S., Olliaro P.L. Miltefosine in the treatment of leishmaniasis: clinical evidence for informed clinical risk management. Ther Clin Risk Manag 2007, 3:733-740.
    • (2007) Ther Clin Risk Manag , vol.3 , pp. 733-740
    • Sundar, S.1    Olliaro, P.L.2
  • 32
    • 6344244521 scopus 로고    scopus 로고
    • Effect of the lysophospholipid analogues edelfosine, ilmofosine and miltefosine against Leishmania amazonensis
    • Santa-Rita R.M., Henriques-Pons A., Barbosa H.S., Castro S.L. Effect of the lysophospholipid analogues edelfosine, ilmofosine and miltefosine against Leishmania amazonensis. J Antimicrob Chemother 2004, 54:704-710.
    • (2004) J Antimicrob Chemother , vol.54 , pp. 704-710
    • Santa-Rita, R.M.1    Henriques-Pons, A.2    Barbosa, H.S.3    Castro, S.L.4
  • 33
    • 33847685204 scopus 로고    scopus 로고
    • In vitro activity of perifosine: a novel alkylphospholipid against the promastigote stage of Leishmania species
    • Cabrera-Serra M.G., Lorenzo-Morales J., Romero M., Valladares B., Pinero J.E. In vitro activity of perifosine: a novel alkylphospholipid against the promastigote stage of Leishmania species. Parasitol Res 2007, 100:1155-1157.
    • (2007) Parasitol Res , vol.100 , pp. 1155-1157
    • Cabrera-Serra, M.G.1    Lorenzo-Morales, J.2    Romero, M.3    Valladares, B.4    Pinero, J.E.5
  • 34
    • 55149104592 scopus 로고    scopus 로고
    • In vivo activity of perifosine against Leishmania amazonensis
    • Cabrera-Serra M.G., Valladares B., Piñero J.E. In vivo activity of perifosine against Leishmania amazonensis. Acta Trop 2008, 108:20-25.
    • (2008) Acta Trop , vol.108 , pp. 20-25
    • Cabrera-Serra, M.G.1    Valladares, B.2    Piñero, J.E.3
  • 35
    • 28044436746 scopus 로고    scopus 로고
    • A phase II dose-increasing study of sitamaquine for the treatment of visceral leishmaniasis in Kenya
    • Wasunna M.K., Rashid J.R., Mbui L., Kirigi G., Kinoti D., Lodenyo H., et al. A phase II dose-increasing study of sitamaquine for the treatment of visceral leishmaniasis in Kenya. Am J Trop Med Hyg 2005, 73:871-876.
    • (2005) Am J Trop Med Hyg , vol.73 , pp. 871-876
    • Wasunna, M.K.1    Rashid, J.R.2    Mbui, L.3    Kirigi, G.4    Kinoti, D.5    Lodenyo, H.6
  • 36
    • 0036335635 scopus 로고    scopus 로고
    • Drug sensitivity of Leishmania species: some unresolved problems
    • Croft S.L., Yardley V., Kendrick H. Drug sensitivity of Leishmania species: some unresolved problems. Trans R Soc Trop Med Hyg 2002, 96:127-129.
    • (2002) Trans R Soc Trop Med Hyg , vol.96 , pp. 127-129
    • Croft, S.L.1    Yardley, V.2    Kendrick, H.3
  • 38
    • 0029068622 scopus 로고
    • A randomized, placebo-controlled trial in Tunisia treating cutaneous leishmaniasis with paromomycin ointment
    • Ben Salah A., Zakraoui H., Zaatour A., Ftaiti A., Zaafouri B., Garraoui A., et al. A randomized, placebo-controlled trial in Tunisia treating cutaneous leishmaniasis with paromomycin ointment. Am J Trop Med Hyg 1995, 53:162-166.
    • (1995) Am J Trop Med Hyg , vol.53 , pp. 162-166
    • Ben Salah, A.1    Zakraoui, H.2    Zaatour, A.3    Ftaiti, A.4    Zaafouri, B.5    Garraoui, A.6
  • 39
    • 3242707018 scopus 로고    scopus 로고
    • Comparison of the effectiveness of two topical paromomycin treatments versus meglumine antimoniate for New World cutaneous leishmaniasis
    • Armijos R.X., Weigel M.M., Calvopiña M., Mancheno M., Rodriguez R. Comparison of the effectiveness of two topical paromomycin treatments versus meglumine antimoniate for New World cutaneous leishmaniasis. Acta Trop 2004, 91:153-160.
    • (2004) Acta Trop , vol.91 , pp. 153-160
    • Armijos, R.X.1    Weigel, M.M.2    Calvopiña, M.3    Mancheno, M.4    Rodriguez, R.5
  • 40
    • 12344263066 scopus 로고    scopus 로고
    • Activity of a paromomycin hydrophilic formulation for topical treatment of infections by Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis
    • Gonçalves G.S., Fernandes A.P., Souza R.C., Cardoso J.E., Oliveira-Silva F., Maciel F.C., et al. Activity of a paromomycin hydrophilic formulation for topical treatment of infections by Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis. Acta Trop 2005, 93:161-167.
    • (2005) Acta Trop , vol.93 , pp. 161-167
    • Gonçalves, G.S.1    Fernandes, A.P.2    Souza, R.C.3    Cardoso, J.E.4    Oliveira-Silva, F.5    Maciel, F.C.6
  • 41
    • 0028008676 scopus 로고
    • Medicinal plants in the fight against leishmaniasis
    • Iwu M.M., Jackson J.E., Schuster B.G. Medicinal plants in the fight against leishmaniasis. Parasitol Today 1994, 10:65-68.
    • (1994) Parasitol Today , vol.10 , pp. 65-68
    • Iwu, M.M.1    Jackson, J.E.2    Schuster, B.G.3
  • 43
    • 70349485574 scopus 로고    scopus 로고
    • New compounds of natural resources in 2008
    • Wang J., Peng Q., Li G. New compounds of natural resources in 2008. Afr J Biotechnol 2009, 8:4299-4307.
    • (2009) Afr J Biotechnol , vol.8 , pp. 4299-4307
    • Wang, J.1    Peng, Q.2    Li, G.3
  • 44
    • 0035238881 scopus 로고    scopus 로고
    • Plants as source of drugs
    • Rates S.M. Plants as source of drugs. Toxicon 2001, 39:603-613.
    • (2001) Toxicon , vol.39 , pp. 603-613
    • Rates, S.M.1
  • 45
    • 0031885559 scopus 로고    scopus 로고
    • Which extractant should be used for the screening and isolation of antimicrobial components from plants?
    • Eloff J.N. Which extractant should be used for the screening and isolation of antimicrobial components from plants?. J Ethnopharmacol 1998, 60:1-8.
    • (1998) J Ethnopharmacol , vol.60 , pp. 1-8
    • Eloff, J.N.1
  • 46
    • 70149117263 scopus 로고    scopus 로고
    • Natural products as a foundation for drug discovery
    • 9.11.1
    • Beutler J.A. Natural products as a foundation for drug discovery. Curr Protoc Pharmacol 2009, 46. 9.11.1.
    • (2009) Curr Protoc Pharmacol , vol.46
    • Beutler, J.A.1
  • 48
    • 0030176285 scopus 로고    scopus 로고
    • Leishmania amazonensis: cultivation and characterization of axenic amastigote-like organisms
    • Hodgkinson V.H., Soong L., Duboise S.M., McMahon-Pratt D. Leishmania amazonensis: cultivation and characterization of axenic amastigote-like organisms. Exp Parasitol 1996, 83:94-105.
    • (1996) Exp Parasitol , vol.83 , pp. 94-105
    • Hodgkinson, V.H.1    Soong, L.2    Duboise, S.M.3    McMahon-Pratt, D.4
  • 49
    • 33745196673 scopus 로고    scopus 로고
    • Current scenario of drug development for leishmaniasis
    • Croft S.L., Seifert K., Yardley V. Current scenario of drug development for leishmaniasis. Indian J Med Res 2006, 123:399-410.
    • (2006) Indian J Med Res , vol.123 , pp. 399-410
    • Croft, S.L.1    Seifert, K.2    Yardley, V.3
  • 51
    • 0033991437 scopus 로고    scopus 로고
    • A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue
    • Mikus J., Steverding D. A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue. Parasitol Int 2000, 48:265-269.
    • (2000) Parasitol Int , vol.48 , pp. 265-269
    • Mikus, J.1    Steverding, D.2
  • 52
    • 33646785770 scopus 로고    scopus 로고
    • Development of a semi-automated colorimetric assay for screening anti-leishmanial agents
    • Ganguly S., Bandyopadhyay S., Sarkar A., Chatterjee M. Development of a semi-automated colorimetric assay for screening anti-leishmanial agents. J Microbiol Methods 2006, 66:79-86.
    • (2006) J Microbiol Methods , vol.66 , pp. 79-86
    • Ganguly, S.1    Bandyopadhyay, S.2    Sarkar, A.3    Chatterjee, M.4
  • 53
    • 0037351148 scopus 로고    scopus 로고
    • A microplate assay for Leishmania amazonensis promastigotes expressing multimeric green fluorescent protein
    • Chan M.M., Bulinski J.C., Chang K.P., Fong D. A microplate assay for Leishmania amazonensis promastigotes expressing multimeric green fluorescent protein. Parasitol Res 2003, 89:266-271.
    • (2003) Parasitol Res , vol.89 , pp. 266-271
    • Chan, M.M.1    Bulinski, J.C.2    Chang, K.P.3    Fong, D.4
  • 55
    • 68249135710 scopus 로고    scopus 로고
    • High-throughput screening of amastigotes of Leishmania donovani clinical isolates against drugs using a colorimetric beta-lactamase assay
    • Mandal S., Maharjan M., Ganguly S., Chatterjee M., Singh S., Buckner F.S., et al. High-throughput screening of amastigotes of Leishmania donovani clinical isolates against drugs using a colorimetric beta-lactamase assay. Indian J Exp Biol 2009, 47:475-479.
    • (2009) Indian J Exp Biol , vol.47 , pp. 475-479
    • Mandal, S.1    Maharjan, M.2    Ganguly, S.3    Chatterjee, M.4    Singh, S.5    Buckner, F.S.6
  • 59
    • 26944449701 scopus 로고    scopus 로고
    • In vitro cytotoxic, antileishmanial and antifungal activities of ethnopharmacologically selected Gabonese plants
    • Lamidi M., DiGiorgio C., Delmas F., Favel A., Eyele Mve-Mba C., Rondi M.L., et al. In vitro cytotoxic, antileishmanial and antifungal activities of ethnopharmacologically selected Gabonese plants. J Ethnopharmacol 2005, 14:185-190.
    • (2005) J Ethnopharmacol , vol.14 , pp. 185-190
    • Lamidi, M.1    DiGiorgio, C.2    Delmas, F.3    Favel, A.4    Eyele Mve-Mba, C.5    Rondi, M.L.6
  • 60
    • 34249103544 scopus 로고    scopus 로고
    • Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae)
    • Castillo D., Arevalo J., Herrera F., Ruiz C., Rojas R., Rengifo E., et al. Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae). J Ethnopharmacol 2007, 13:410-414.
    • (2007) J Ethnopharmacol , vol.13 , pp. 410-414
    • Castillo, D.1    Arevalo, J.2    Herrera, F.3    Ruiz, C.4    Rojas, R.5    Rengifo, E.6
  • 61
    • 21644460351 scopus 로고    scopus 로고
    • Screening of New Caledonian and Vanuatu medicinal plants for antiprotozoal activity
    • Billo M., Fournet A., Cabalion P., Waikedre J., Bories C., Loiseau P., et al. Screening of New Caledonian and Vanuatu medicinal plants for antiprotozoal activity. J Ethnopharmacol 2005, 15:569-575.
    • (2005) J Ethnopharmacol , vol.15 , pp. 569-575
    • Billo, M.1    Fournet, A.2    Cabalion, P.3    Waikedre, J.4    Bories, C.5    Loiseau, P.6
  • 63
    • 67349083969 scopus 로고    scopus 로고
    • Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata
    • Karioti A., Skaltsa H., Kaiser M., Tasdemir D. Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata. Phytomedicine 2009, 16:783-787.
    • (2009) Phytomedicine , vol.16 , pp. 783-787
    • Karioti, A.1    Skaltsa, H.2    Kaiser, M.3    Tasdemir, D.4
  • 64
    • 70349832783 scopus 로고    scopus 로고
    • In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia D. C. (Asteraceae)
    • Silva Filho A.A., Resende D.O., Fukui M.J., Santos F.F., Pauletti P.M., Cunha W.R., et al. In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia D. C. (Asteraceae). Fitoterapia 2009, 80:478-482.
    • (2009) Fitoterapia , vol.80 , pp. 478-482
    • Silva Filho, A.A.1    Resende, D.O.2    Fukui, M.J.3    Santos, F.F.4    Pauletti, P.M.5    Cunha, W.R.6
  • 65
    • 67349122667 scopus 로고    scopus 로고
    • Medicinal plants from the Yanesha (Peru): evaluation of the leishmanicidal and antimalarial activity of selected extracts
    • Valadeau C., Pabon A., Deharo E., Albán-Castillo J., Estevez Y., Lores F.A., et al. Medicinal plants from the Yanesha (Peru): evaluation of the leishmanicidal and antimalarial activity of selected extracts. J Ethnopharmacol 2009, 123:413-422.
    • (2009) J Ethnopharmacol , vol.123 , pp. 413-422
    • Valadeau, C.1    Pabon, A.2    Deharo, E.3    Albán-Castillo, J.4    Estevez, Y.5    Lores, F.A.6
  • 66
    • 76749108892 scopus 로고    scopus 로고
    • Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis
    • Gachet M.S., Lecaro J.S., Kaiser M., Brun R., Navarrete H., Muñoz R.A., et al. Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis. J Ethnopharmacol 2010, 2:184-197.
    • (2010) J Ethnopharmacol , vol.2 , pp. 184-197
    • Gachet, M.S.1    Lecaro, J.S.2    Kaiser, M.3    Brun, R.4    Navarrete, H.5    Muñoz, R.A.6
  • 70
  • 71
    • 34547123324 scopus 로고    scopus 로고
    • Antileishmanial activity of crude extract and coumarin from Calophyllum brasiliense leaves against Leishmania amazonensis
    • Brenzan M.A., Nakamura C.V., Dias Filho B.P., Ueda-Nakamura T., Young M.C., Cortez D.A. Antileishmanial activity of crude extract and coumarin from Calophyllum brasiliense leaves against Leishmania amazonensis. Parasitol Res 2007, 101:715-722.
    • (2007) Parasitol Res , vol.101 , pp. 715-722
    • Brenzan, M.A.1    Nakamura, C.V.2    Dias Filho, B.P.3    Ueda-Nakamura, T.4    Young, M.C.5    Cortez, D.A.6
  • 74
    • 26044431994 scopus 로고    scopus 로고
    • New clerodane diterpenoids from Laetia procera (Poepp.) Eichler (Flacourtiaceae), with antiplasmodial and antileishmanial activities
    • Jullian V., Bonduelle C., Valentin A., Acebey L., Duigou A.G., Prévost M.F., et al. New clerodane diterpenoids from Laetia procera (Poepp.) Eichler (Flacourtiaceae), with antiplasmodial and antileishmanial activities. Bioorg Med Chem Lett 2005, 15:5065-5070.
    • (2005) Bioorg Med Chem Lett , vol.15 , pp. 5065-5070
    • Jullian, V.1    Bonduelle, C.2    Valentin, A.3    Acebey, L.4    Duigou, A.G.5    Prévost, M.F.6
  • 75
    • 31044444243 scopus 로고    scopus 로고
    • Comparative antiplasmodial, leishmanicidal and antitrypanosomal activities of several biflavonoids
    • Weniger B., Vonthron-Sénécheau C., Kaiser M., Brun R., Anton R. Comparative antiplasmodial, leishmanicidal and antitrypanosomal activities of several biflavonoids. Phytomedicine 2006, 13:176-180.
    • (2006) Phytomedicine , vol.13 , pp. 176-180
    • Weniger, B.1    Vonthron-Sénécheau, C.2    Kaiser, M.3    Brun, R.4    Anton, R.5
  • 78
    • 29344470308 scopus 로고    scopus 로고
    • A triterpenoid saponin possessing antileishmanial activity from the leaves of Careya arborea
    • Mandal D., Panda N., Kumar S., Banerjee S., Mandal N.B., Sahu N.P. A triterpenoid saponin possessing antileishmanial activity from the leaves of Careya arborea. Phytochemistry 2006, 67:183-190.
    • (2006) Phytochemistry , vol.67 , pp. 183-190
    • Mandal, D.1    Panda, N.2    Kumar, S.3    Banerjee, S.4    Mandal, N.B.5    Sahu, N.P.6
  • 79
    • 64949112719 scopus 로고    scopus 로고
    • Leishmanicidal effect of LLD-3 (1), a nor-triterpene isolated from Lophanthera lactescens
    • Danelli M.G., Soares D.C., Abreu H.S., Peçanha L.M., Saraiva E.M. Leishmanicidal effect of LLD-3 (1), a nor-triterpene isolated from Lophanthera lactescens. Phytochemistry 2009, 70:608-614.
    • (2009) Phytochemistry , vol.70 , pp. 608-614
    • Danelli, M.G.1    Soares, D.C.2    Abreu, H.S.3    Peçanha, L.M.4    Saraiva, E.M.5
  • 80
    • 33845671368 scopus 로고    scopus 로고
    • In vitro and in vivo leishmanicidal activity of Dysoxylum binectariferum and its fractions against Leishmania donovani
    • Lakshmi V., Pandey K., Kapil A., Singh N., Samant M., Dube A. In vitro and in vivo leishmanicidal activity of Dysoxylum binectariferum and its fractions against Leishmania donovani. Phytomedicine 2007, 14:36-42.
    • (2007) Phytomedicine , vol.14 , pp. 36-42
    • Lakshmi, V.1    Pandey, K.2    Kapil, A.3    Singh, N.4    Samant, M.5    Dube, A.6
  • 81
    • 77951902633 scopus 로고    scopus 로고
    • Chemistry, cytotoxicity and antileishmanial activity of the essential oil from Piper auritum
    • Monzote L., García M., Montalvo A.M., Scull R., Miranda M. Chemistry, cytotoxicity and antileishmanial activity of the essential oil from Piper auritum. Mem Inst Oswaldo Cruz 2010, 105:168-173.
    • (2010) Mem Inst Oswaldo Cruz , vol.105 , pp. 168-173
    • Monzote, L.1    García, M.2    Montalvo, A.M.3    Scull, R.4    Miranda, M.5
  • 82
    • 35048888447 scopus 로고    scopus 로고
    • Evaluation of the leishmanicidal activity of plants used by Peruvian Chayahuita ethnic group
    • Estevez Y., Castillo D., Pisango M.T., Arevalo J., Rojas R., Alban J., et al. Evaluation of the leishmanicidal activity of plants used by Peruvian Chayahuita ethnic group. J Ethnopharmacol 2007, 1:254-259.
    • (2007) J Ethnopharmacol , vol.1 , pp. 254-259
    • Estevez, Y.1    Castillo, D.2    Pisango, M.T.3    Arevalo, J.4    Rojas, R.5    Alban, J.6
  • 83
    • 77951620436 scopus 로고    scopus 로고
    • Evaluation of antileishmanial activity of eupomatenoid-5, a compound isolated from leaves of Piper regnellii var. pallescens
    • Vendrametto M.C., Santos A.O., Nakamura C.V., Dias-Filho B.P., Cortez D.A., Ueda-Nakamura T. Evaluation of antileishmanial activity of eupomatenoid-5, a compound isolated from leaves of Piper regnellii var. pallescens. Parasitol Int 2010, 59:154-158.
    • (2010) Parasitol Int , vol.59 , pp. 154-158
    • Vendrametto, M.C.1    Santos, A.O.2    Nakamura, C.V.3    Dias-Filho, B.P.4    Cortez, D.A.5    Ueda-Nakamura, T.6
  • 84
    • 70350222212 scopus 로고    scopus 로고
    • In vitro activity of the essential oil of Cymbopogon citratus and its major component (citral) on Leishmania amazonensis
    • Santin M.R., Santos A.O., Nakamura C.V., Dias-Filho B.P., Ferreira I.C., Ueda-Nakamura T. In vitro activity of the essential oil of Cymbopogon citratus and its major component (citral) on Leishmania amazonensis. Parasitol Res 2009, 105:1489-1496.
    • (2009) Parasitol Res , vol.105 , pp. 1489-1496
    • Santin, M.R.1    Santos, A.O.2    Nakamura, C.V.3    Dias-Filho, B.P.4    Ferreira, I.C.5    Ueda-Nakamura, T.6
  • 85
    • 77953017254 scopus 로고    scopus 로고
    • Coumarins from Galipea panamensis and their activity against Leishmania panamensis
    • Arango V., Robledo S., Séon-Méniel B., Figadère B., Cardona W., Sáez J., et al. Coumarins from Galipea panamensis and their activity against Leishmania panamensis. J Nat Prod 2010, 28:1012-1014.
    • (2010) J Nat Prod , vol.28 , pp. 1012-1014
    • Arango, V.1    Robledo, S.2    Séon-Méniel, B.3    Figadère, B.4    Cardona, W.5    Sáez, J.6
  • 86
    • 38949211763 scopus 로고    scopus 로고
    • Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila
    • Tasdemir D., Brun R., Franzblau S.G., Sezgin Y., Calis I. Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila. Phytomedicine 2008, 15:209-215.
    • (2008) Phytomedicine , vol.15 , pp. 209-215
    • Tasdemir, D.1    Brun, R.2    Franzblau, S.G.3    Sezgin, Y.4    Calis, I.5
  • 87
    • 33846643541 scopus 로고    scopus 로고
    • Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes
    • Iranshahi M., Arfa P., Ramezani M., Jaafari M.R., Sadeghian H., Bassarello C., et al. Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes. Phytochemistry 2007, 68:554-561.
    • (2007) Phytochemistry , vol.68 , pp. 554-561
    • Iranshahi, M.1    Arfa, P.2    Ramezani, M.3    Jaafari, M.R.4    Sadeghian, H.5    Bassarello, C.6
  • 89
    • 58549093170 scopus 로고    scopus 로고
    • Redox-active dinitrodiphenylthioethers against Leishmania: synthesis, structure-activity relationships and mechanism of action studies
    • Delfín D.A., Morgan R.E., Zhu X., Werbovetz K.A. Redox-active dinitrodiphenylthioethers against Leishmania: synthesis, structure-activity relationships and mechanism of action studies. Bioorg Med Chem 2009, 17:820-829.
    • (2009) Bioorg Med Chem , vol.17 , pp. 820-829
    • Delfín, D.A.1    Morgan, R.E.2    Zhu, X.3    Werbovetz, K.A.4
  • 91
    • 64249139717 scopus 로고    scopus 로고
    • Synthesis and antileishmanial activity of novel 2,4,6-trisubstituted pyrimidines and 1,3,5-triazines
    • Sunduru N., Nishi, Palne S., Chauhan P.M., Gupta S. Synthesis and antileishmanial activity of novel 2,4,6-trisubstituted pyrimidines and 1,3,5-triazines. Eur J Med Chem 2009, 44:2473-2481.
    • (2009) Eur J Med Chem , vol.44 , pp. 2473-2481
    • Sunduru, N.1    Nishi Palne, S.2    Chauhan, P.M.3    Gupta, S.4
  • 92
    • 61349102501 scopus 로고    scopus 로고
    • Improved synthesis of seven aromatic Baylis-Hillman adducts (BHA): evaluation against Artemia salina Leach. and Leishmania chagasi
    • Barbosa T.P., Junior C.G., Silva F.P., Lopes H.M., Figueiredo L.R., Sousa S.C., et al. Improved synthesis of seven aromatic Baylis-Hillman adducts (BHA): evaluation against Artemia salina Leach. and Leishmania chagasi. Eur J Med Chem 2009, 44:1726-1730.
    • (2009) Eur J Med Chem , vol.44 , pp. 1726-1730
    • Barbosa, T.P.1    Junior, C.G.2    Silva, F.P.3    Lopes, H.M.4    Figueiredo, L.R.5    Sousa, S.C.6
  • 93
    • 57749083122 scopus 로고    scopus 로고
    • Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity
    • Musonda C.C., Whitlock G.A., Witty M.J., Brun R., Kaiser M. Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity. Bioorg Med Chem Lett 2009, 19:401-405.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 401-405
    • Musonda, C.C.1    Whitlock, G.A.2    Witty, M.J.3    Brun, R.4    Kaiser, M.5
  • 95
    • 57749116985 scopus 로고    scopus 로고
    • Aryloxy cyclohexyl imidazoles: a novel class of antileishmanial agents
    • Srinivas N., Palne S., Nishi, Gupta S., Bhandari K. Aryloxy cyclohexyl imidazoles: a novel class of antileishmanial agents. Bioorg Med Chem Lett 2009, 15:324-327.
    • (2009) Bioorg Med Chem Lett , vol.15 , pp. 324-327
    • Srinivas, N.1    Palne, S.2    Nishi Gupta, S.3    Bhandari, K.4
  • 96
    • 77954309552 scopus 로고    scopus 로고
    • Antitrypanosomal and antileishmanial activities of novel N-alkyl-(1-phenylsubstituted-beta-carboline)-3-carboxamides
    • Tonin L.T., Panice M.R., Nakamura C.V., Rocha K.J., Santos A.O., Ueda-Nakamura T., et al. Antitrypanosomal and antileishmanial activities of novel N-alkyl-(1-phenylsubstituted-beta-carboline)-3-carboxamides. Biomed Pharmacother 2010, 64:386-389.
    • (2010) Biomed Pharmacother , vol.64 , pp. 386-389
    • Tonin, L.T.1    Panice, M.R.2    Nakamura, C.V.3    Rocha, K.J.4    Santos, A.O.5    Ueda-Nakamura, T.6
  • 97
    • 77950520679 scopus 로고    scopus 로고
    • Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines
    • Aponte J.C., Vaisberg A.J., Castillo D., Gonzalez G., Estevez Y., Arevalo J., et al. Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines. Bioorg Med Chem 2010, 18:2880-2886.
    • (2010) Bioorg Med Chem , vol.18 , pp. 2880-2886
    • Aponte, J.C.1    Vaisberg, A.J.2    Castillo, D.3    Gonzalez, G.4    Estevez, Y.5    Arevalo, J.6
  • 101
    • 70450221930 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticles based drug delivery systems
    • Kumari A., Yadav S.K., Yadav S.C. Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf B Biointerfaces 2010, 75:1-18.
    • (2010) Colloids Surf B Biointerfaces , vol.75 , pp. 1-18
    • Kumari, A.1    Yadav, S.K.2    Yadav, S.C.3
  • 102
    • 34548049483 scopus 로고    scopus 로고
    • Nanosizing-oral formulation development and biopharmaceutical evaluation
    • Kesisoglou F., Panmai S., Wu Y. Nanosizing-oral formulation development and biopharmaceutical evaluation. Adv Drug Deliv Rev 2007, 59:631-644.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 631-644
    • Kesisoglou, F.1    Panmai, S.2    Wu, Y.3
  • 103
    • 23644437163 scopus 로고    scopus 로고
    • Therapeutic potential of nanoparticulate systems for macrophage targeting
    • Chellat F., Merhi Y., Moreau A., Yahia L.H. Therapeutic potential of nanoparticulate systems for macrophage targeting. Biomaterials 2005, 26:7260-7275.
    • (2005) Biomaterials , vol.26 , pp. 7260-7275
    • Chellat, F.1    Merhi, Y.2    Moreau, A.3    Yahia, L.H.4
  • 104
    • 34547901070 scopus 로고    scopus 로고
    • Parasitic diseases: liposomes and polymeric nanoparticles versus lipid nanoparticles
    • Date A.A., Joshi M.S., Patravale V.B. Parasitic diseases: liposomes and polymeric nanoparticles versus lipid nanoparticles. Adv Drug Deliv Rev 2007, 59:505-521.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 505-521
    • Date, A.A.1    Joshi, M.S.2    Patravale, V.B.3
  • 105
    • 0035937599 scopus 로고    scopus 로고
    • Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future
    • Müller R.H., Jacobs C., Kayser O. Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future. Adv Drug Deliv Rev 2001, 47:3-19.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 3-19
    • Müller, R.H.1    Jacobs, C.2    Kayser, O.3
  • 106
    • 0037453179 scopus 로고    scopus 로고
    • Formulation of amphotericin B as nanosuspension for oral administration
    • Kayser O., Olbrich C., Yardley V., Kiderlen A.F., Croft S.L. Formulation of amphotericin B as nanosuspension for oral administration. Int J Pharm 2003, 254:73-75.
    • (2003) Int J Pharm , vol.254 , pp. 73-75
    • Kayser, O.1    Olbrich, C.2    Yardley, V.3    Kiderlen, A.F.4    Croft, S.L.5
  • 108
    • 37849010813 scopus 로고    scopus 로고
    • Lipid nanoparticles for alkyl lysophospholipid edelfosine encapsulation: development and in vitro characterization
    • Mendoza A.E., Rayo M., Mollinedo F., Blanco-Prieto M.J. Lipid nanoparticles for alkyl lysophospholipid edelfosine encapsulation: development and in vitro characterization. Eur J Pharm Biopharm 2008, 68:207-213.
    • (2008) Eur J Pharm Biopharm , vol.68 , pp. 207-213
    • Mendoza, A.E.1    Rayo, M.2    Mollinedo, F.3    Blanco-Prieto, M.J.4
  • 109
    • 34247641821 scopus 로고    scopus 로고
    • Role of plant lipid transfer proteins in plant cell physiology-a concise review
    • Carvalho A.O., Gomes V.M. Role of plant lipid transfer proteins in plant cell physiology-a concise review. Peptides 2007, 28:1144-1153.
    • (2007) Peptides , vol.28 , pp. 1144-1153
    • Carvalho, A.O.1    Gomes, V.M.2
  • 110
    • 0033782344 scopus 로고    scopus 로고
    • Purification and structural characterization of LTP1 polypeptides from beer
    • Jégou S., Douliez J., Mollé D., Boivin P., Marion D. Purification and structural characterization of LTP1 polypeptides from beer. J Agric Food Chem 2000, 48:5023-5029.
    • (2000) J Agric Food Chem , vol.48 , pp. 5023-5029
    • Jégou, S.1    Douliez, J.2    Mollé, D.3    Boivin, P.4    Marion, D.5
  • 111
    • 4344577995 scopus 로고    scopus 로고
    • Lipid binding in rice nonspecific lipid transfer protein-1 complexes from Oryza sativa
    • Cheng H.C., Cheng P.T., Peng P., Lyu P.C., Sun Y.J. Lipid binding in rice nonspecific lipid transfer protein-1 complexes from Oryza sativa. Protein Sci 2004, 13:2304-2315.
    • (2004) Protein Sci , vol.13 , pp. 2304-2315
    • Cheng, H.C.1    Cheng, P.T.2    Peng, P.3    Lyu, P.C.4    Sun, Y.J.5
  • 112
    • 34247267633 scopus 로고    scopus 로고
    • Isolation and characterization of a tomato non-specific lipid transfer protein involved in polygalacturonase-mediated pectin degradation
    • Tomassen M.M., Barrett D.M., Van Der Valk H.C., Woltering E.J. Isolation and characterization of a tomato non-specific lipid transfer protein involved in polygalacturonase-mediated pectin degradation. J Exp Bot 2007, 58:1151-1160.
    • (2007) J Exp Bot , vol.58 , pp. 1151-1160
    • Tomassen, M.M.1    Barrett, D.M.2    Van Der Valk, H.C.3    Woltering, E.J.4
  • 113
    • 33645381694 scopus 로고    scopus 로고
    • Purification and characterization of non-specific lipid transfer proteins from the leaves of Pandanus amaryllifolius (Pandanaceae)
    • Ooi L.S., Wong E.Y., Sun S.S., Ooi V.E. Purification and characterization of non-specific lipid transfer proteins from the leaves of Pandanus amaryllifolius (Pandanaceae). Peptides 2006, 27:626-632.
    • (2006) Peptides , vol.27 , pp. 626-632
    • Ooi, L.S.1    Wong, E.Y.2    Sun, S.S.3    Ooi, V.E.4
  • 114
    • 67649877982 scopus 로고    scopus 로고
    • Isolation, purification and characterization of a nonspecific lipid transfer protein from Cuminum cyminum
    • Zaman U., Abbasi A. Isolation, purification and characterization of a nonspecific lipid transfer protein from Cuminum cyminum. Phytochemistry 2009, 70:979-987.
    • (2009) Phytochemistry , vol.70 , pp. 979-987
    • Zaman, U.1    Abbasi, A.2
  • 116
    • 65849094308 scopus 로고    scopus 로고
    • WR279,396, a third generation aminoglycoside ointment for the treatment of Leishmania major cutaneous leishmaniasis: a phase 2, randomized, double blind, placebo controlled study
    • Ben Salah A., Buffet P.A., Morizot G., Ben Massoud N., Zâatour A., Ben Alaya N., et al. WR279,396, a third generation aminoglycoside ointment for the treatment of Leishmania major cutaneous leishmaniasis: a phase 2, randomized, double blind, placebo controlled study. PLoS Negl Trop Dis 2009, 3:e432.
    • (2009) PLoS Negl Trop Dis , vol.3
    • Ben Salah, A.1    Buffet, P.A.2    Morizot, G.3    Ben Massoud, N.4    Zâatour, A.5    Ben Alaya, N.6
  • 117
    • 0036299135 scopus 로고    scopus 로고
    • The interaction index: a measure of drug synergism
    • Tallarida R.J. The interaction index: a measure of drug synergism. Pain 2002, 98:163-168.
    • (2002) Pain , vol.98 , pp. 163-168
    • Tallarida, R.J.1
  • 118
    • 34548655035 scopus 로고    scopus 로고
    • Combined effect of the essential oil from Chenopodium ambrosioides and antileishmanial drugs on promastigotes of Leishmania amazonensis
    • Monzote L., Montalvo A.M., Scull R., Miranda M., Abreu J. Combined effect of the essential oil from Chenopodium ambrosioides and antileishmanial drugs on promastigotes of Leishmania amazonensis. Rev Inst Med Trop Sao Paulo 2007, 49:257-260.
    • (2007) Rev Inst Med Trop Sao Paulo , vol.49 , pp. 257-260
    • Monzote, L.1    Montalvo, A.M.2    Scull, R.3    Miranda, M.4    Abreu, J.5
  • 119
    • 59849116161 scopus 로고    scopus 로고
    • Synergy research: approaching a new generation of phytopharmaceuticals
    • Wagner H., Ulrich-Merzenich G. Synergy research: approaching a new generation of phytopharmaceuticals. Phytomedicine 2009, 16:97-110.
    • (2009) Phytomedicine , vol.16 , pp. 97-110
    • Wagner, H.1    Ulrich-Merzenich, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.