New clerodane diterpenoids from Laetia procera (Poepp.) Eichler (Flacourtiaceae), with antiplasmodial and antileishmanial activities

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 22, 2005, Pages 5065-5070

  Jullian, Valérie ^a   Bonduelle, Colin ^a   Valentin, Alexis ^a   Acebey, Lucia ^a   Duigou, Anne Gaëlle ^a   Prévost, Marie Francoise ^b   Sauvain, Michel ^a  

^a Université Paul Sabatier   (France)

^b Centre IRD de Cayenne   (France)

Author keywords

Butanolide; Clerodane diterpenoids; Flacourtiaceae; Laetia procera; Leishmania; Plasmodium falciparum

Indexed keywords

CLERODANE DERIVATIVE; DITERPENOID; LAETIANOLIDE A; LAETIAPROCERINE A; LAETIAPROCERINE B; LAETIAPROCERINE C; LAETIAPROCERINE D; UNCLASSIFIED DRUG;

AMASTIGOTE; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOASSAY; CELL STRAIN MCF 7; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SELECTIVITY; DRUG STRUCTURE; IC 50; IN VITRO STUDY; LAETIA PROCERA; LEISHMANIA; MEDICINAL PLANT; NUCLEAR MAGNETIC RESONANCE; PLASMODIUM FALCIPARUM; PROMASTIGOTE; STRUCTURE ACTIVITY RELATION; TUMOR CELL CULTURE;

ANIMALS; ANTIMALARIALS; CELL LINE, TUMOR; DITERPENES; DITERPENES, CLERODANE; HUMANS; INHIBITORY CONCENTRATION 50; LEISHMANIA; MAGNETIC RESONANCE SPECTROSCOPY; MAGNOLIA; MOLECULAR STRUCTURE; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

FLACOURTIACEAE; LAETIA PROCERA; LEISHMANIA AMAZONENSIS; MINK CELL FOCUS-FORMING VIRUS; PLASMODIUM FALCIPARUM;

EID: 26044431994     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.090     Document Type: Article

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