Improved synthesis of seven aromatic Baylis-Hillman adducts (BHA): Evaluation against Artemia salina Leach. and Leishmania chagasi

European Journal of Medicinal Chemistry

Volumn 44, Issue 4, 2009, Pages 1726-1730

  Barbosa, Ticiano P ^a   Junior, Cláudio G L ^a   Silva, Fábio P L ^a   Lopes, Horacimone M ^a   Figueiredo, Lucas R F ^a   Sousa, Suervy C O ^a   Batista, Guilherme N ^a   da Silva, Thiago G ^a   Silva, Tania M S ^a,b   de Oliveira, Márcia R ^a   Vasconcellos, Mário L A A ^a  

^a FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^b FEDERAL UNIVERSITY OF BAHIA   (Brazil)

Author keywords

Artemia salina Leach.; Baylis Hillman adducts; Green chemistry; Leishmania chagasi

Indexed keywords

2 [HYDROXY(2 NITROPHENYL)METHYL]ACRYLONITRILE; 2 [HYDROXY(3 NITROPHENYL)METHYL]ACRYLONITRILE; 2 [HYDROXY(4 BROMOPHENYL)METHYL]ACRYLONITRILE; 2 [HYDROXY(4 NITROPHENYL)METHYL]ACRYLONITRILE; 2 [HYDROXY(PYRIDIN 2 YL)METHYL]ACRYLONITRILE; 2 [HYDROXY(PYRIDIN 3 YL)METHYL]ACRYLONITRILE; 2 [HYDROXY(PYRIDIN 4 YL)METHYL]ACRYLONITRILE; ACRYLONITRILE; ANTIPROTOZOAL AGENT; DIMETHYL SULFOXIDE; MEGLUMINE ANTIMONATE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTEMIA; ARTEMIA SALINA LEACH; ARTICLE; BAYLIS HILLMAN REACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; IC 50; LC 50; LEISHMANIA CHAGASI; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ASSAY; REACTION TIME;

ANIMALS; ANTIPROTOZOAL AGENTS; ARTEMIA; INHIBITORY CONCENTRATION 50; LEISHMANIA; ORGANIC CHEMICALS;

EID: 61349102501     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.03.016     Document Type: Article

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