Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae)

Journal of Ethnopharmacology

Volumn 112, Issue 2, 2007, Pages 410-414

  Castillo, D ^a   Arevalo, J ^a,c   Herrera, F ^a   Ruiz, C ^b   Rojas, R ^c   Rengifo, E ^d   Vaisberg, A ^c   Lock, O ^b   Lemesre, J L ^e   Gornitzka, H ^f   Sauvain, M ^g  

^a INSTITUTO DE MEDICINA TROPICAL ALEXANDER VON HUMBOLDT   (Peru)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DEL PERÚ   (Peru)

^c UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

^d INSTITUTO DE INVESTIGACIONES DE LA AMAZONÍA PERUANA   (Peru)

^e INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

^f UMR 5069) 118 route de Narbonne   (France)

^g UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Axenic amastigotes; Ethnomedicine; Himatanthus sucuuba; Leishmania amazonensis; Peru; Plumericin

Indexed keywords

AMPHOTERICIN B; ANTILEISHMANIAL AGENT; IRIDOID; ISOPLUMERICIN; PLUMERICIN; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; APOCYNACEAE; ARTICLE; HIMATANTHUS SUCUUBA; IN VITRO STUDY; LEISHMANIA; NONHUMAN; PERU;

ANIMALS; ANTIPROTOZOAL AGENTS; APOCYNACEAE; BALB 3T3 CELLS; BIOLOGICAL ASSAY; CERCOPITHECUS AETHIOPS; CRYSTALLOGRAPHY, X-RAY; ETHNOBOTANY; HUMANS; INDENES; INDIANS, SOUTH AMERICAN; IRIDOIDS; LEISHMANIA MEXICANA; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEDICINE, TRADITIONAL; MICE; MICE, INBRED BALB C; PERU; PLANT EXTRACTS; SPIRONOLACTONE; VERO CELLS;

APOCYNACEAE; HIMATANTHUS SUCUUBA; LEISHMANIA AMAZONENSIS; PICEA; UTA;

EID: 34249103544     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2007.03.025     Document Type: Article

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