Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Biomedicine and Pharmacotherapy

Volumn 62, Issue 9, 2008, Pages 651-658

  Brenzan, Mislaine Adriana ^a   Nakamura, Celso Vataru ^a   Dias Filho, Benedito Prado ^a   Ueda Nakamura, Tânia ^a   Young, Maria Claudia M ^b   Côrrea, Arlene Gonçalves ^c   Júnior, Joel Alvim ^c   dos Santos, Adriana Oliveira ^d   Cortez, Diógenes Aparício Garcia ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b Pós graduação em Biodiversidade Vegetal e Meio Ambiente   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^d STATE UNIVERSITY OF LONDRINA   (Brazil)

Author keywords

( ) Mammea A BB derivatives; Antileishmanial activity; Calophyllum brasiliense; Coumarins; Cytotoxic activity

Indexed keywords

5,7 DIHYDROXY 4 PHENYLCOUMARIN; 5,7 DIHYDROXY 8 (2 METHYLBUTANOYL) 6 (3 METHYLBUTYL) 4 PHENYLCHROMAN 2 ONE; 5,7 DIMETHOXY 8 (1 METHOXY 2 METHYLBUTYL) 6 (3 METHYLBUT 2 EN 1 YL) 4 PHENYLCOUMARIN; 5,7 DIMETHOXY 8 (2 METHYLBUTANOYL) 6 (3 METHYLBUT 2 EN 1 YL) 4 PHENYLCOUMARIN; 7 HYDROXY 5 METHOXY 8 (2 METHYLBUTANOYL) 6 (3 METHYLBUT 2 EN 1 YL) 4 PHENYLCOUMARIN; CALOPHYLLUM BRASILIENSE EXTRACT; COUMARIN; COUMARIN DERIVATIVE; MAMMEA A BB; MAMMEA B BB; PLANT EXTRACT; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CALOPHYLLUM; CALOPHYLLUM BRASILIENSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; LEISHMANIA; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMASTIGOTE; STRUCTURE ACTIVITY RELATION;

ANIMALS; CALOPHYLLUM; CELL LINE; COUMARINS; LEISHMANIA; MACROPHAGES; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS;

EID: 54049094332     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2008.08.024     Document Type: Article

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