-
1
-
-
78249277673
-
Nitrogen mustard therapy. Use of methyl-bis(β-chloroethyl)amine hydrochloride and tris(β-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders
-
Goodman, L. S. et al. Nitrogen mustard therapy. Use of methyl-bis(β-chloroethyl)amine hydrochloride and tris(β-chloroethyl) amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders. J. Am. Med. Assoc. 132, 126-132 (1946).
-
(1946)
J. Am. Med. Assoc.
, vol.132
, pp. 126-132
-
-
Goodman, L.S.1
-
2
-
-
0022476924
-
Reevaluation of interaction of cis-dichloro(ethylenediamine)platinum(II) with DNA
-
Eastman, A. Reevaluation of interaction of cis-dichloro(ethylenediamine) platinum(II) with DNA. Biochemistry 25, 3912-3915 (1986). (Pubitemid 16042519)
-
(1986)
Biochemistry
, vol.25
, Issue.13
, pp. 3912-3915
-
-
Eastman, A.1
-
3
-
-
0029433337
-
Structural and function modification of DNA by mitomycin C. Mechanism of the DNA sequence specificity of mitomycins
-
Gargiulo, D., Kumar, G. S., Musser, S. S. & Tomasz, M. Structural and function modification of DNA by mitomycin C. Mechanism of the DNA sequence specificity of mitomycins. Nucleic Acids Symp. Ser. 169-170 (1995).
-
(1995)
Nucleic Acids Symp. Ser.
, pp. 169-170
-
-
Gargiulo, D.1
Kumar, G.S.2
Musser, S.S.3
Tomasz, M.4
-
4
-
-
0037425575
-
DNA interchain cross-links formed by acrolein and crotonaldehyde
-
DOI 10.1021/ja020778f
-
Kozekov, I. D. et al. DNA interchain cross-links formed by acrolein and crotonaldehyde. J. Am. Chem. Soc. 125, 50-61 (2003). (Pubitemid 36068643)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.1
, pp. 50-61
-
-
Kozekov, I.D.1
Nechev, L.V.2
Moseley, M.S.3
Harris, C.M.4
Rizzo, C.J.5
Stone, M.P.6
Harris, T.M.7
-
5
-
-
49049091162
-
Interstrand DNA cross-links induced by α β-unsaturated aldehydes derived from lipid peroxidation and environmental sources
-
Stone, M. P. et al. Interstrand DNA cross-links induced by α, β-unsaturated aldehydes derived from lipid peroxidation and environmental sources. Acc. Chem. Res. 41, 793-804 (2008).
-
(2008)
Acc. Chem. Res.
, vol.41
, pp. 793-804
-
-
Stone, M.P.1
-
6
-
-
23144448354
-
DNA adducts from acetaldehyde: Implications for alcohol-related carcinogenesis
-
DOI 10.1016/j.alcohol.2005.03.009, PII S0741832905000947
-
Brooks, P. J. & Theruvathu, J. A. DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis. Alcohol 35, 187-193 (2005). (Pubitemid 41079922)
-
(2005)
Alcohol
, vol.35
, Issue.3
, pp. 187-193
-
-
Brooks, P.J.1
Theruvathu, J.A.2
-
7
-
-
84984555005
-
A high fat diet inhibits δ-aminolevulinate dehydratase and increases lipid peroxidation in mice (Mus musculus)
-
Folmer, V., Soares, J. C., Gabriel, D. & Rocha, J. B. A high fat diet inhibits δ-aminolevulinate dehydratase and increases lipid peroxidation in mice (Mus musculus). J. Nutr. 133, 2165-2170 (2003). (Pubitemid 36841533)
-
(2003)
Journal of Nutrition
, vol.133
, Issue.7
, pp. 2165-2170
-
-
Folmer, V.1
Soares, J.C.M.2
Gabriel, D.3
Rocha, J.B.T.4
-
8
-
-
0025091727
-
Severe phototoxic burn following celery ingestion
-
DOI 10.1001/archderm.126.10.1334
-
Ljunggren, B. Severe phototoxic burn following celery ingestion. Arch. Dermatol. 126, 1334-1336 (1990). (Pubitemid 20344617)
-
(1990)
Archives of Dermatology
, vol.126
, Issue.10
, pp. 1334-1336
-
-
Ljunggren, B.1
-
9
-
-
0031058624
-
Isolation and identification of antimicrobial furocoumarins from parsley
-
Manderfeld, M. M., Schafer, H. W., Davidson, P. M. & Zottola, E. A. Isolation and identification of antimicrobial furocoumarins from parsley. J. Food Prot. 60, 72-77 (1997). (Pubitemid 27114819)
-
(1997)
Journal of Food Protection
, vol.60
, Issue.1
, pp. 72-77
-
-
Manderfeld, M.M.1
Schafer, H.W.2
Davidson, P.M.3
Zottola, E.A.4
-
10
-
-
0019314088
-
5-Methoxypsoralen, an ingredient in several suntan preparations, has lethal, mutagenic and clastogenic properties
-
DOI 10.1038/285407a0
-
Ashwood-Smith, M. J., Poulton, G. A., Barker, M. & Mildenberger, M. 5-Methoxypsoralen, an ingredient in several suntan preparations, has lethal, mutagenic and clastogenic properties. Nature 285, 407-409 (1980). (Pubitemid 10047222)
-
(1980)
Nature
, vol.285
, Issue.5764
, pp. 407-409
-
-
Ashwood-Smith, M.J.1
Poulton, G.A.2
Barker, M.3
Mildenberger, M.4
-
11
-
-
33847323023
-
Interstrand cross-links generated by abasic sites in duplex DNA
-
Dutta, S., Chowdhury, G. & Gates, K. S. Interstrand cross-links generated by abasic sites in duplex DNA. J. Am. Chem. Soc. 129, 1852-1853 (2007).
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 1852-1853
-
-
Dutta, S.1
Chowdhury, G.2
Gates, K.S.3
-
12
-
-
42649139906
-
Impact of estrogenic compounds on DNA integrity in human spermatozoa: Evidence for cross-linking and redox cycling activities
-
Bennetts, L. E. et al. Impact of estrogenic compounds on DNA integrity in human spermatozoa: evidence for cross-linking and redox cycling activities. Mutat. Res. 641, 1-11 (2008).
-
(2008)
Mutat. Res.
, vol.641
, pp. 1-11
-
-
Bennetts, L.E.1
-
13
-
-
0023251468
-
Toxicity of 8-methoxypsoralen, 5-methoxypsoralen, 3-carbethoxypsoralen, or 5-methylisopsoralen with ultraviolet radiation in the hairless (HRA/Skh) Mouse
-
DOI 10.1016/0041-008X(87)90177-3
-
Dunnick, J. K., Forbes, P. D., Davies, R. E. & Iverson, W. O. Toxicity of 8-methoxypsoralen, 5-methoxypsoralen, 3-carbethoxypsoralen, or 5-methylisopsoralen with ultraviolet radiation in the hairless (HRA/Skh) mouse. Toxicol. Appl. Pharmacol. 89, 73-80 (1987). (Pubitemid 17106657)
-
(1987)
Toxicology and Applied Pharmacology
, vol.89
, Issue.1
, pp. 73-80
-
-
Dunnick, J.K.1
Forbes, P.D.2
Davies, R.E.3
Iverson, W.O.4
-
16
-
-
0023835089
-
Risk of second cancers after treatment for Hodgkin's disease
-
Tucker, M. A., Coleman, C. N., Cox, R. S., Varghese, A. & Rosenberg, S. A. Risk of second cancers after treatment for Hodgkin's disease. N. Engl. J. Med. 318, 76-81 (1988). (Pubitemid 18029298)
-
(1988)
New England Journal of Medicine
, vol.318
, Issue.2
, pp. 76-81
-
-
Tucker, M.A.1
Coleman, C.N.2
Cox, R.S.3
Varghese, A.4
Rosenberg, S.A.5
-
17
-
-
0033521949
-
Risk of leukemia after platinum-based chemotherapy for ovarian cancer
-
DOI 10.1056/NEJM199902043400504
-
Travis, L. B. et al. Risk of leukemia after platinum-based chemotherapy for ovarian cancer. N. Engl. J. Med. 340, 351-357 (1999). (Pubitemid 29090800)
-
(1999)
New England Journal of Medicine
, vol.340
, Issue.5
, pp. 351-357
-
-
Travis, L.B.1
Holowaty, E.J.2
Bergfeldt, K.3
Lynch, C.F.4
Kohler, B.A.5
Wiklund, T.6
Curtis, R.E.7
Hall, P.8
Andersson, M.9
Pukkala, E.10
Sturgeon, J.11
Stovall, M.12
-
18
-
-
0014112634
-
Familial constitutional panmyelocytopathy Fanconi's anemia (F. A.). I. Clinical aspects
-
Fanconi, G. Familial constitutional panmyelocytopathy, Fanconi's anemia (F. A.). I. Clinical aspects. Semin. Hematol. 4, 233-240 (1967).
-
(1967)
Semin. Hematol.
, vol.4
, pp. 233-240
-
-
Fanconi, G.1
-
19
-
-
29244489543
-
Fanconi anemia (cross)linked to DNA repair
-
DOI 10.1016/j.cell.2005.12.009, PII S0092867405013917
-
Niedernhofer, L. J., Lalai, A. S. & Hoeijmakers, J. H. Fanconi anemia (cross)linked to DNA repair. Cell 123, 1191-1198 (2005). (Pubitemid 41821778)
-
(2005)
Cell
, vol.123
, Issue.7
, pp. 1191-1198
-
-
Niedernhofer, L.J.1
Lalai, A.S.2
Hoeijmakers, J.H.J.3
-
20
-
-
63049094474
-
Monoubiquitylation in the Fanconi anemia DNA damage response pathway
-
Alpi, A. F. & Patel, K. J. Monoubiquitylation in the Fanconi anemia DNA damage response pathway. DNA Repair 8, 430-435 (2009).
-
(2009)
DNA Repair
, vol.8
, pp. 430-435
-
-
Alpi, A.F.1
Patel, K.J.2
-
21
-
-
0024041895
-
A test for Fanconi's anemia
-
Auerbach, A. D. A test for Fanconi's anemia. Blood 72, 366-367 (1988).
-
(1988)
Blood
, vol.72
, pp. 366-367
-
-
Auerbach, A.D.1
-
22
-
-
67650095306
-
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
-
Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).
-
(2009)
Nature
, vol.460
, pp. 53-59
-
-
Raya, A.1
-
23
-
-
0037306904
-
Cancer incidence in persons with Fanconi anemia
-
DOI 10.1182/blood-2002-05-1498
-
Rosenberg, P. S., Greene, M. H. & Alter, B. P. Cancer incidence in persons with Fanconi anemia. Blood 101, 822-826 (2003). (Pubitemid 36139345)
-
(2003)
Blood
, vol.101
, Issue.3
, pp. 822-826
-
-
Rosenberg, P.S.1
Greene, M.H.2
Alter, B.P.3
-
24
-
-
0028068579
-
Hematologic abnormalities in Fanconi anemia: An International Fanconi Anemia Registry study
-
Butturini, A. et al. Hematologic abnormalities in Fanconi anemia: an International Fanconi Anemia Registry study. Blood 84, 1650-1655 (1994). (Pubitemid 24273037)
-
(1994)
Blood
, vol.84
, Issue.5
, pp. 1650-1655
-
-
Butturini, A.1
Gale, R.P.2
Verlander, P.C.3
Adler-Brecher, B.4
Gillio, A.P.5
Auerbach, A.D.6
-
25
-
-
0034672154
-
Association of complementation group and mutation type with clinical outcome in Fanconi anemia
-
Faivre, L. et al. Association of complementation group and mutation type with clinical outcome in Fanconi anemia. Blood 96, 4064-4070 (2000).
-
(2000)
Blood
, vol.96
, pp. 4064-4070
-
-
Faivre, L.1
-
26
-
-
1642315917
-
Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood
-
DOI 10.1182/blood-2003-06-1970
-
Hirsch, B. et al. Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood. Blood 103, 2554-2559 (2004). (Pubitemid 38393006)
-
(2004)
Blood
, vol.103
, Issue.7
, pp. 2554-2559
-
-
Hirsch, B.1
Shimamura, A.2
Moreau, L.3
Baldinger, S.4
Hag-Alshiekh, M.5
Bostrom, B.6
Sencer, S.7
D'Andrea, A.D.8
-
27
-
-
33846569450
-
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
-
DOI 10.1038/ng1947, PII NG1947
-
Reid, S. et al. Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N. and predispose to childhood cancer. Nature Genet. 39, 162-164 (2007). (Pubitemid 46184345)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 162-164
-
-
Reid, S.1
Schindler, D.2
Hanenberg, H.3
Barker, K.4
Hanks, S.5
Kalb, R.6
Neveling, K.7
Kelly, P.8
Seal, S.9
Freund, M.10
Wurm, M.11
Batish, S.D.12
Lach, F.P.13
Yetgin, S.14
Neitzel, H.15
Ariffin, H.16
Tischkowitz, M.17
Mathew, C.G.18
Auerbach, A.D.19
Rahman, N.20
more..
-
28
-
-
33846415079
-
Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2
-
DOI 10.1136/jmg.2006.043257
-
Alter, B. P., Rosenberg, P. S. & Brody, L. C. Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2. J. Med. Genet. 44, 1-9 (2007). (Pubitemid 46142832)
-
(2007)
Journal of Medical Genetics
, vol.44
, Issue.1
, pp. 1-9
-
-
Alter, B.P.1
Rosenberg, P.S.2
Brody, L.C.3
-
29
-
-
67649652057
-
Identification and characterization of mutations in FANCL gene: A second case of Fanconi anemia belonging to FA-L complementation group
-
Ali, A. M. et al. Identification and characterization of mutations in FANCL gene: a second case of Fanconi anemia belonging to FA-L complementation group. Hum. Mutat. 30, E761-E770 (2009).
-
(2009)
Hum. Mutat.
, vol.30
-
-
Ali, A.M.1
-
30
-
-
25144449181
-
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M
-
DOI 10.1038/ng1626, PII NG1626
-
Meetei, A. R. et al. A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. Nature Genet. 37, 958-963 (2005). (Pubitemid 43086152)
-
(2005)
Nature Genetics
, vol.37
, Issue.9
, pp. 958-963
-
-
Meetei, A.R.1
Medhurst, A.L.2
Ling, C.3
Xue, Y.4
Singh, T.R.5
Bier, P.6
Steltenpool, J.7
Stone, S.8
Dokal, I.9
Mathew, C.G.10
Hoatlin, M.11
Joenje, H.12
De Winter, J.P.13
Wang, W.14
-
31
-
-
77951747926
-
Mutation of the RAD51C gene in a Fanconi anemia-like disorder
-
Vaz, F. et al. Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nature Genet. 42, 406-409 (2010).
-
(2010)
Nature Genet.
, vol.42
, pp. 406-409
-
-
Vaz, F.1
-
32
-
-
79953832617
-
Origin, functional role, and clinical impact of Fanconi anemia FANCA mutations
-
Castella, M. et al. Origin, functional role, and clinical impact of Fanconi anemia FANCA mutations. Blood 117, 3759-3769 (2011).
-
(2011)
Blood
, vol.117
, pp. 3759-3769
-
-
Castella, M.1
-
33
-
-
0037228326
-
High incidence of head and neck squamous cell carcinoma in patients with Fanconi anemia
-
Kutler, D. I. et al. High incidence of head and neck squamous cell carcinoma in patients with Fanconi anemia. Arch. Otolaryngol. Head Neck Surg. 129, 106-112 (2003). (Pubitemid 36070885)
-
(2003)
Archives of Otolaryngology - Head and Neck Surgery
, vol.129
, Issue.1
, pp. 106-112
-
-
Kutler, D.I.1
Auerbach, A.D.2
Satagopan, J.3
Giampietro, P.F.4
Batish, S.D.5
Huvos, A.G.6
Goberdhan, A.7
Shah, J.P.8
Singh, B.9
-
34
-
-
14544297485
-
Myelodysplastic syndrome
-
DOI 10.1146/annurev.med.56.082103.104704
-
Hofmann, W. K. & Koeffler, H. P. Myelodysplastic syndrome. Annu. Rev. Med. 56, 1-16 (2005). (Pubitemid 40299770)
-
(2005)
Annual Review of Medicine
, vol.56
, pp. 1-16
-
-
Hofmann, W.-K.1
Koeffler, H.P.2
-
35
-
-
79958221787
-
Using mouse models to investigate the biological and physiological consequences of defects in the Fanconi anaemia/ breast cancer DNA repair signalling pathway
-
doi:10.1002/path.2903
-
Tischkowitz, M. & Winqvist, R. Using mouse models to investigate the biological and physiological consequences of defects in the Fanconi anaemia/ breast cancer DNA repair signalling pathway. J. Pathol. 9 Mar 2011 (doi:10.1002/path.2903).
-
J. Pathol. 9 Mar 2011
-
-
Tischkowitz, M.1
Winqvist, R.2
-
36
-
-
0038603848
-
Clonal chromosomal aberrations in bone marrow cells of Fanconi anemia patients: Gains of the chromosomal segment 3q26q29 as an adverse risk factor
-
DOI 10.1182/blood-2002-10-3243
-
Tonnies, H. et al. Clonal chromosomal aberrations in bone marrow cells of Fanconi anemia patients: gains of the chromosomal segment 3q26q29 as an adverse risk factor. Blood 101, 3872-3874 (2003). (Pubitemid 36857860)
-
(2003)
Blood
, vol.101
, Issue.10
, pp. 3872-3874
-
-
Tonnies, H.1
Huber, S.2
Kuhl, J.-S.3
Gerlach, A.4
Ebell, W.5
Neitzel, H.6
-
37
-
-
79954595653
-
Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions
-
Quentin, S. et al. Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions. Blood 117, e161-e170 (2011).
-
(2011)
Blood
, vol.117
-
-
Quentin, S.1
-
38
-
-
0027249768
-
- lymphocytes and glycophorin A variants erythrocytes in Fanconi anemia patients, their parents and control donors
-
DOI 10.1016/0027-5107(93)90137-5
-
Sala-Trepat, M., Boyse, J., Richard, P., Papadopoulo, D. & Moustacchi, E. Frequencies of HPRT- lymphocytes and glycophorin A variants erythrocytes in Fanconi anemia patients, their parents and control donors. Mutat. Res. 289, 115-126 (1993). (Pubitemid 23261952)
-
(1993)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.289
, Issue.1
, pp. 115-126
-
-
Sala-Trepat, M.1
Boyse, J.2
Richard, P.3
Papadopoulo, D.4
Moustacchi, E.5
-
39
-
-
15744364715
-
Interstrand crosslink-induced homologous recombination carries an increased risk of deletions and insertions
-
DOI 10.1016/j.dnarep.2005.02.002
-
Jonnalagadda, V. S., Matsuguchi, T. & Engelward, B. P. Interstrand crosslink-induced homologous recombination carries an increased risk of deletions and insertions. DNA Repair 4, 594-605 (2005). (Pubitemid 40462047)
-
(2005)
DNA Repair
, vol.4
, Issue.5
, pp. 594-605
-
-
Jonnalagadda, V.S.1
Matsuguchi, T.2
Engelward, B.P.3
-
40
-
-
33746503650
-
The Fanconi anemia pathway limits the severity of mutagenesis
-
DOI 10.1016/j.dnarep.2006.05.039, PII S1568786406001789
-
Hinz, J. M., Nham, P. B., Salazar, E. P. & Thompson, L. H. The Fanconi anemia pathway limits the severity of mutagenesis. DNA Repair 5, 875-884 (2006). (Pubitemid 44137487)
-
(2006)
DNA Repair
, vol.5
, Issue.8
, pp. 875-884
-
-
Hinz, J.M.1
Nham, P.B.2
Salazar, E.P.3
Thompson, L.H.4
-
41
-
-
0030953165
-
Deregulated apoptosis is a hallmark of the Fanconi anemia syndrome
-
Ridet, A. et al. Deregulated apoptosis is a hallmark of the Fanconi anemia syndrome. Cancer Res. 57, 1722-1730 (1997). (Pubitemid 27199666)
-
(1997)
Cancer Research
, vol.57
, Issue.9
, pp. 1722-1730
-
-
Ridet, A.1
Guillouf, C.2
Duchaud, E.3
Cundari, E.4
Fiore, M.5
Moustacchi, E.6
Rosselli, F.7
-
42
-
-
33644846696
-
Risk of selected subsequent carcinomas in survivors of childhood cancer: A report from the childhood cancer survivor study
-
DOI 10.1200/JCO.2005.02.7235
-
Bassal, M. et al. Risk of selected subsequent carcinomas in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J. Clin. Oncol. 24, 476-483 (2006). (Pubitemid 46630467)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.3
, pp. 476-483
-
-
Bassal, M.1
Mertens, A.C.2
Taylor, L.3
Neglia, J.P.4
Greffe, B.S.5
Hammond, S.6
Ronckers, C.M.7
Friedman, D.L.8
Stovall, M.9
Yasui, Y.Y.10
Robison, L.L.11
Meadows, A.T.12
Kadan-Lottick, N.S.13
-
43
-
-
34250001450
-
DNA repair is limiting for haematopoietic stem cells during ageing
-
DOI 10.1038/nature05875, PII NATURE05875
-
Nijnik, A. et al. DNA repair is limiting for haematopoietic stem cells during ageing. Nature 447, 686-690 (2007). (Pubitemid 46889732)
-
(2007)
Nature
, vol.447
, Issue.7145
, pp. 686-690
-
-
Nijnik, A.1
Woodbine, L.2
Marchetti, C.3
Dawson, S.4
Lambe, T.5
Liu, C.6
Rodrigues, N.P.7
Crockford, T.L.8
Cabuy, E.9
Vindigni, A.10
Enver, T.11
Bell, J.I.12
Slijepcevic, P.13
Goodnow, C.C.14
Jeggo, P.A.15
Cornall, R.J.16
-
44
-
-
0037441890
-
-/- hematopoietic stem cells and decreases the risk of clonal evolution
-
DOI 10.1182/blood-2002-08-2404
-
-/- hematopoietic stem cells and decreases the risk of clonal evolution. Blood 101, 1299-1307 (2003). (Pubitemid 36182499)
-
(2003)
Blood
, vol.101
, Issue.4
, pp. 1299-1307
-
-
Haneline, L.S.1
Li, X.2
Ciccone, S.L.M.3
Hong, P.4
Yang, Y.5
Broxmeyer, H.E.6
Lee, S.-H.7
Orazi, A.8
Srour, E.F.9
Clapp, D.W.10
-
45
-
-
78649944103
-
Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer
-
Park, J. W. et al. Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer. Cancer Res. 70, 9959-9968 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 9959-9968
-
-
Park, J.W.1
-
46
-
-
78650946998
-
Spontaneous abrogation of the G2 DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients
-
Ceccaldi, R. et al. Spontaneous abrogation of the G2 DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients. J. Clin. Invest. 121, 184-194 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 184-194
-
-
Ceccaldi, R.1
-
47
-
-
0030060945
-
FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: Direct evidence for the coincidence of viral integration sites and fragile sites
-
DOI 10.1093/hmg/5.2.187
-
Wilke, C. M. et al. FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites. Hum. Mol. Genet. 5, 187-195 (1996). (Pubitemid 26036914)
-
(1996)
Human Molecular Genetics
, vol.5
, Issue.2
, pp. 187-195
-
-
Wilke, C.M.1
Hall, B.K.2
Hoge, A.3
Paradee, W.4
Smith, D.I.5
Glover, T.W.6
-
48
-
-
0345720836
-
Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia patients
-
Kutler, D. I. et al. Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia Patients. J. Natl Cancer Inst. 95, 1718-1721 (2003). (Pubitemid 37509080)
-
(2003)
Journal of the National Cancer Institute
, vol.95
, Issue.22
, pp. 1718-1721
-
-
Kutler, D.I.1
Wreesmann, V.B.2
Goberdhan, A.3
Ben-Porat, L.4
Satagopan, J.5
Ngai, I.6
Huvos, A.G.7
Giampietro, P.8
Levran, O.9
Pujara, K.10
Diotti, R.11
Carlson, D.12
Huryn, L.A.13
Auerbach, A.D.14
Singh, B.15
-
49
-
-
56749181183
-
Clinical and molecular characteristics of squamous cell carcinomas from Fanconi anemia patients
-
van Zeeburg, H. J. et al. Clinical and molecular characteristics of squamous cell carcinomas from Fanconi anemia patients. J. Natl Cancer Inst. 100, 1649-1653 (2008).
-
(2008)
J. Natl Cancer Inst.
, vol.100
, pp. 1649-1653
-
-
Van Zeeburg, H.J.1
-
50
-
-
50649091874
-
Structural and functional relationships of the XPF/MUS81 family of proteins
-
Ciccia, A., McDonald, N. & West, S. C. Structural and functional relationships of the XPF/MUS81 family of proteins. Annu. Rev. Biochem. 77, 259-287 (2008).
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 259-287
-
-
Ciccia, A.1
McDonald, N.2
West, S.C.3
-
51
-
-
0035105291
-
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
-
DOI 10.1016/S1097-2765(01)00173-3
-
Garcia-Higuera, I. et al. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol. Cell 7, 249-262 (2001). (Pubitemid 32206493)
-
(2001)
Molecular Cell
, vol.7
, Issue.2
, pp. 249-262
-
-
Garcia-Higuera, I.1
Taniguchi, T.2
Ganesan, S.3
Meyn M.Stephen4
Timmers, C.5
Hejna, J.6
Grompe, M.7
D'Andrea, A.D.8
-
52
-
-
34247110291
-
Identification of the FANCI Protein, a Monoubiquitinated FANCD2 Paralog Required for DNA Repair
-
DOI 10.1016/j.cell.2007.03.009, PII S0092867407003200
-
Smogorzewska, A. et al. Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell 129, 289-301 (2007). (Pubitemid 46584733)
-
(2007)
Cell
, vol.129
, Issue.2
, pp. 289-301
-
-
Smogorzewska, A.1
Matsuoka, S.2
Vinciguerra, P.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
Ballif, B.A.7
Gygi, S.P.8
Hofmann, K.9
D'Andrea, A.D.10
Elledge, S.J.11
-
53
-
-
24944461145
-
A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair
-
DOI 10.1016/j.molcel.2005.08.018, PII S1097276505015601
-
Matsushita, N. et al. A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair. Mol. Cell 19, 841-847 (2005). (Pubitemid 41316677)
-
(2005)
Molecular Cell
, vol.19
, Issue.6
, pp. 841-847
-
-
Matsushita, N.1
Kitao, H.2
Ishiai, M.3
Nagashima, N.4
Hirano, S.5
Okawa, K.6
Ohta, T.7
Yu, D.S.8
McHugh, P.J.9
Hickson, I.D.10
Venkitaraman, A.R.11
Kurumizaka, H.12
Takata, M.13
-
54
-
-
33847059931
-
The Fanconi Anemia Signalosome Anchor
-
DOI 10.1016/j.molcel.2007.02.002, PII S1097276507000810
-
Niedernhofer, L. J. The Fanconi anemia signalosome anchor. Mol. Cell 25, 487-490 (2007). (Pubitemid 46274451)
-
(2007)
Molecular Cell
, vol.25
, Issue.4
, pp. 487-490
-
-
Niedernhofer, L.J.1
-
55
-
-
46749106037
-
Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24
-
Kim, J. M., Kee, Y., Gurtan, A. & D'Andrea, A. D. Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24. Blood 111, 5215-5222 (2008).
-
(2008)
Blood
, vol.111
, pp. 5215-5222
-
-
Kim, J.M.1
Kee, Y.2
Gurtan, A.3
D'Andrea, A.D.4
-
56
-
-
70350751416
-
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing
-
Remus, D. et al. Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139, 719-730 (2009).
-
(2009)
Cell
, vol.139
, pp. 719-730
-
-
Remus, D.1
-
57
-
-
51549098159
-
Mechanism of replication-coupled DNA interstrand crosslink repair
-
Raschle, M. et al. Mechanism of replication-coupled DNA interstrand crosslink repair. Cell 134, 969-980 (2008).
-
(2008)
Cell
, vol.134
, pp. 969-980
-
-
Raschle, M.1
-
58
-
-
33846799430
-
Identification of FAAP24, a Fanconi Anemia Core Complex Protein that Interacts with FANCM
-
DOI 10.1016/j.molcel.2007.01.003, PII S109727650700007X
-
Ciccia, A. et al. Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. Mol. Cell 25, 331-343 (2007). (Pubitemid 46206138)
-
(2007)
Molecular Cell
, vol.25
, Issue.3
, pp. 331-343
-
-
Ciccia, A.1
Ling, C.2
Coulthard, R.3
Yan, Z.4
Xue, Y.5
Meetei, A.R.6
Laghmani, E.H.7
Joenje, H.8
McDonald, N.9
De Winter, J.P.10
Wang, W.11
West, S.C.12
-
59
-
-
72149090671
-
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
-
Deans, A. J. & West, S. C. FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia. Mol. Cell 36, 943-953 (2009).
-
(2009)
Mol. Cell
, vol.36
, pp. 943-953
-
-
Deans, A.J.1
West, S.C.2
-
60
-
-
77949563363
-
MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM
-
Singh, T. R. et al. MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. Mol. Cell 37, 879-886 (2010).
-
(2010)
Mol. Cell
, vol.37
, pp. 879-886
-
-
Singh, T.R.1
-
61
-
-
77949701960
-
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability
-
Yan, Z. et al. A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol. Cell 37, 865-878 (2010).
-
(2010)
Mol. Cell
, vol.37
, pp. 865-878
-
-
Yan, Z.1
-
62
-
-
33646691283
-
Histone H2B Monoubiquitination Functions Cooperatively with FACT to Regulate Elongation by RNA Polymerase II
-
DOI 10.1016/j.cell.2006.04.029, PII S0092867406005708
-
Pavri, R. et al. Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell 125, 703-717 (2006). (Pubitemid 43732350)
-
(2006)
Cell
, vol.125
, Issue.4
, pp. 703-717
-
-
Pavri, R.1
Zhu, B.2
Li, G.3
Trojer, P.4
Mandal, S.5
Shilatifard, A.6
Reinberg, D.7
-
63
-
-
33749188883
-
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
-
van der Horst, A. et al. FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nature Cell Biol. 8, 1064-1073 (2006).
-
(2006)
Nature Cell Biol.
, vol.8
, pp. 1064-1073
-
-
Van Der Horst, A.1
-
64
-
-
2942705849
-
Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin
-
DOI 10.1128/MCB.24.13.5850-5862.2004
-
Wang, X., Andreassen, P. R. & D'Andrea, A. D. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol. Cell. Biol. 24, 5850-5862 (2004). (Pubitemid 38787970)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.13
, pp. 5850-5862
-
-
Wang, X.1
Andreassen, P.R.2
D'Andrea, A.D.3
-
65
-
-
69949164038
-
FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL
-
Longerich, S., San Filippo, J., Liu, D. & Sung, P. FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL. J. Biol. Chem. 284, 23182-23186 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 23182-23186
-
-
Longerich, S.1
San Filippo, J.2
Liu, D.3
Sung, P.4
-
66
-
-
69249216420
-
MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair
-
Roques, C. et al. MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair. EMBO J. 28, 2400-2413 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 2400-2413
-
-
Roques, C.1
-
67
-
-
59649114341
-
Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype
-
Kim, J. M. et al. Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Dev. Cell 16, 314-320 (2009).
-
(2009)
Dev. Cell
, vol.16
, pp. 314-320
-
-
Kim, J.M.1
-
68
-
-
77954286076
-
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair
-
Smogorzewska, A. et al. A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. Mol. Cell 39, 36-47 (2010).
-
(2010)
Mol. Cell
, vol.39
, pp. 36-47
-
-
Smogorzewska, A.1
-
69
-
-
77954279611
-
Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents
-
Kratz, K. et al. Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents. Cell 142, 77-88 (2010).
-
(2010)
Cell
, vol.142
, pp. 77-88
-
-
Kratz, K.1
-
70
-
-
77954274685
-
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2
-
MacKay, C. et al. Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell 142, 65-76 (2010).
-
(2010)
Cell
, vol.142
, pp. 65-76
-
-
MacKay, C.1
-
71
-
-
75749121458
-
DNA polymerase POLN participates in cross-link repair and homologous recombination
-
Moldovan, G.-L. et al. DNA polymerase POLN participates in cross-link repair and homologous recombination. Mol. Cell. Biol. 30, 1088-1096 (2010).
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1088-1096
-
-
Moldovan, G.-L.1
-
72
-
-
33747432986
-
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress
-
DOI 10.1083/jcb.200602108
-
Woodward, A. M. et al. Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress. J. Cell Biol. 173, 673-683 (2006). (Pubitemid 46165576)
-
(2006)
Journal of Cell Biology
, vol.173
, Issue.5
, pp. 673-683
-
-
Woodward, A.M.1
Gohler, T.2
Luciani, M.G.3
Oehlmann, M.4
Ge, X.5
Gartner, A.6
Jackson, D.A.7
Blow, J.J.8
-
73
-
-
33845914051
-
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
-
DOI 10.1038/nature05456, PII NATURE05456
-
Niedernhofer, L. J. et al. A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis. Nature 444, 1038-1043 (2006). (Pubitemid 46018517)
-
(2006)
Nature
, vol.444
, Issue.7122
, pp. 1038-1043
-
-
Niedernhofer, L.J.1
Garinis, G.A.2
Raams, A.3
Lalai, A.S.4
Robinson, A.R.5
Appeldoorn, E.6
Odijk, H.7
Oostendorp, R.8
Ahmad, A.9
Van Leeuwen, W.10
Theil, A.F.11
Vermeulen, W.12
Van Der Horst, G.T.J.13
Meinecke, P.14
Kleijer, W.J.15
Vijg, J.16
Jaspers, N.G.J.17
Hoeijmakers, J.H.J.18
-
74
-
-
33847056347
-
First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure
-
Jaspers, N. G. et al. First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure. Am. J. Hum. Genet. 80, 457-466 (2007).
-
(2007)
Am. J. Hum. Genet.
, vol.80
, pp. 457-466
-
-
Jaspers, N.G.1
-
75
-
-
79251632658
-
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype
-
Stoepker, C. et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nature Genet. 43, 138-141 (2011).
-
(2011)
Nature Genet.
, vol.43
, pp. 138-141
-
-
Stoepker, C.1
-
76
-
-
79251611165
-
Mutations of the SLX4 gene in Fanconi anemia
-
Kim, Y. et al. Mutations of the SLX4 gene in Fanconi anemia. Nature Genet. 43, 142-146 (2011).
-
(2011)
Nature Genet.
, vol.43
, pp. 142-146
-
-
Kim, Y.1
-
77
-
-
33750206776
-
The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks
-
DOI 10.1038/sj.emboj.7601344, PII 7601344
-
Hanada, K. et al. The structure-specific endonuclease MUS81-EME1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J. 25, 4921-4932 (2006). (Pubitemid 44607036)
-
(2006)
EMBO Journal
, vol.25
, Issue.20
, pp. 4921-4932
-
-
Hanada, K.1
Budzowska, M.2
Modesti, M.3
Maas, A.4
Wyman, C.5
Essers, J.6
Kanaar, R.7
-
78
-
-
67649662604
-
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
-
Svendsen, J. M. et al. Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Cell 138, 63-77 (2009).
-
(2009)
Cell
, vol.138
, pp. 63-77
-
-
Svendsen, J.M.1
-
79
-
-
70450224524
-
The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links
-
Al-Minawi, A. Z. et al. The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links. Nucleic Acids Res. 37, 6400-6413 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 6400-6413
-
-
Al-Minawi, A.Z.1
-
80
-
-
0035890270
-
The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells
-
DOI 10.1093/emboj/20.22.6540
-
Niedernhofer, L. J. et al. The structure-specific endonuclease ERCC1-XPF is required for targeted gene replacement in embryonic stem cells. EMBO J. 20, 6540-6549 (2001). (Pubitemid 33078726)
-
(2001)
EMBO Journal
, vol.20
, Issue.22
, pp. 6540-6549
-
-
Niedernhofer, L.J.1
Essers, J.2
Weeda, G.3
Beverloo, B.4
De Wit, J.5
Muijtjens, M.6
Odijk, H.7
Hoeijmakers, J.H.J.8
Kanaar, R.9
-
81
-
-
79953239469
-
Aberrant chromosome morphology in human cells defective for Holliday junction resolution
-
Wechsler, T., Newman, S. & West, S. C. Aberrant chromosome morphology in human cells defective for Holliday junction resolution. Nature 471, 642-646 (2011).
-
(2011)
Nature
, vol.471
, pp. 642-646
-
-
Wechsler, T.1
Newman, S.2
West, S.C.3
-
82
-
-
51849088174
-
Distortion-dependent unhooking of interstrand cross-links in mammalian cell extracts
-
Smeaton, M. B. et al. Distortion-dependent unhooking of interstrand cross-links in mammalian cell extracts. Biochemistry 47, 9920-9930 (2008).
-
(2008)
Biochemistry
, vol.47
, pp. 9920-9930
-
-
Smeaton, M.B.1
-
83
-
-
0029904811
-
The role of DNA mismatch repair in platinum drug resistance
-
Fink, D. et al. The role of DNA mismatch repair in platinum drug resistance. Cancer Res. 56, 4881-4886 (1996). (Pubitemid 26374423)
-
(1996)
Cancer Research
, vol.56
, Issue.21
, pp. 4881-4886
-
-
Fink, D.1
Nebel, S.2
Aebi, S.3
Zheng, H.4
Cenni, B.5
Nehme, A.6
Christen, R.D.7
Howell, S.B.8
-
84
-
-
67650828240
-
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
-
Zhao, J., Jain, A., Iyer, R. R., Modrich, P. L. & Vasquez, K. M. Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks. Nucleic Acids Res. 37, 4420-4429 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 4420-4429
-
-
Zhao, J.1
Jain, A.2
Iyer, R.R.3
Modrich, P.L.4
Vasquez, K.M.5
-
85
-
-
69749095427
-
Checkpoint signaling from a single DNA interstrand crosslink
-
Ben-Yehoyada, M. et al. Checkpoint signaling from a single DNA interstrand crosslink. Mol. Cell 35, 704-715 (2009).
-
(2009)
Mol. Cell
, vol.35
, pp. 704-715
-
-
Ben-Yehoyada, M.1
-
86
-
-
33645312939
-
DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta
-
Sarkar, S., Davies, A. A., Ulrich, H. D. & McHugh, P. J. DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta. EMBO J. 25, 1285-1294 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 1285-1294
-
-
Sarkar, S.1
Davies, A.A.2
Ulrich, H.D.3
McHugh, P.J.4
-
87
-
-
0034100766
-
DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts
-
DOI 10.1128/MCB.20.7.2446-2454.2000
-
Mu, D. et al. DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts. Mol. Cell. Biol. 20, 2446-2454 (2000). (Pubitemid 30152052)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.7
, pp. 2446-2454
-
-
Mu, D.1
Bessho, T.2
Nechev, L.V.3
Chen, D.J.4
Harris, T.M.5
Hearst, J.E.6
Sancar, A.7
-
88
-
-
33847787053
-
Characterization of Z-DNA as a nucleosome-boundary element in yeast Saccharomyces cerevisiae
-
DOI 10.1073/pnas.0611447104
-
Wong, B., Chen, S., Kwon, J. A. & Rich, A. Characterization of Z.-DNA as a nucleosome-boundary element in yeast Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA 104, 2229-2234 (2007). (Pubitemid 46391380)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.7
, pp. 2229-2234
-
-
Wong, B.1
Chen, S.2
Kwon, J.-A.3
Rich, A.4
-
89
-
-
77953915005
-
Ubiquitin signalling in DNA replication and repair
-
Ulrich, H. D. & Walden, H. Ubiquitin signalling in DNA replication and repair. Nature Rev. Mol. Cell Biol. 11, 479-489 (2010).
-
(2010)
Nature Rev. Mol. Cell Biol.
, vol.11
, pp. 479-489
-
-
Ulrich, H.D.1
Walden, H.2
-
90
-
-
67649641641
-
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair
-
Munoz, I. M. et al. Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Mol. Cell 35, 116-127 (2009).
-
(2009)
Mol. Cell
, vol.35
, pp. 116-127
-
-
Munoz, I.M.1
-
91
-
-
0017119299
-
Template primer inactivation by cis- and trans-dichlorodiammine platinum for human DNA polymerase α, β, and Rauscher murine leukemia virus reverse transcriptase, as a mechanism of cytotoxicity
-
Harder, H. C., Smith, R. G. & Leroy, A. F. Template primer inactivation by cis- and trans-dichlorodiammine platinum for human DNA polymerase α, β, and Rauscher murine leukemia virus reverse transcriptase, as a mechanism of cytotoxicity. Cancer Res. 36, 3821-3829 (1976).
-
(1976)
Cancer Res.
, vol.36
, pp. 3821-3829
-
-
Harder, H.C.1
Smith, R.G.2
Leroy, A.F.3
-
92
-
-
18244371925
-
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
-
DOI 10.1101/gad.1301205
-
Byun, T. S., Pacek, M., Yee, M. C., Walter, J. C. & Cimprich, K. A. Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Genes Dev. 19, 1040-1052 (2005). (Pubitemid 40632450)
-
(2005)
Genes and Development
, vol.19
, Issue.9
, pp. 1040-1052
-
-
Byun, T.S.1
Pacek, M.2
Yee, M.-C.3
Walter, J.C.4
Cimprich, K.A.5
-
93
-
-
79251481487
-
DNA polymerases and cancer
-
Lange, S. S., Takata, K. & Wood, R. D. DNA polymerases and cancer. Nature Rev. Cancer 11, 96-110 (2011).
-
(2011)
Nature Rev. Cancer
, vol.11
, pp. 96-110
-
-
Lange, S.S.1
Takata, K.2
Wood, R.D.3
-
94
-
-
70350365400
-
Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif
-
Howlett, N. G., Harney, J. A., Rego, M. A., Kolling, F. W. & Glover, T. W. Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif. J. Biol. Chem. 284, 28935-28942 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28935-28942
-
-
Howlett, N.G.1
Harney, J.A.2
Rego, M.A.3
Kolling, F.W.4
Glover, T.W.5
-
95
-
-
77958499239
-
RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network
-
Geng, L., Huntoon, C. J. & Karnitz, L. M. RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network. J. Cell Biol. 191, 249-257 (2010).
-
(2010)
J. Cell Biol.
, vol.191
, pp. 249-257
-
-
Geng, L.1
Huntoon, C.J.2
Karnitz, L.M.3
-
96
-
-
0038823615
-
Structure and enzymatic properties of a stable complex of the human REV1 and REV7 proteins
-
DOI 10.1074/jbc.M211765200
-
Masuda, Y., Ohmae, M., Masuda, K. & Kamiya, K. Structure and enzymatic properties of a stable complex of the human REV1 and REV7 proteins. J. Biol. Chem. 278, 12356-12360 (2003). (Pubitemid 36800219)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.14
, pp. 12356-12360
-
-
Masuda, Y.1
Ohmae, M.2
Masuda, K.3
Kamiya, K.4
-
97
-
-
77951905220
-
Cross-link structure affects replication-independent DNA interstrand cross-link repair in mammalian cells
-
Hlavin, E. M., Smeaton, M. B., Noronha, A. M., Wilds, C. J. & Miller, P. S. Cross-link structure affects replication-independent DNA interstrand cross-link repair in mammalian cells. Biochemistry 49, 3977-3988 (2010).
-
(2010)
Biochemistry
, vol.49
, pp. 3977-3988
-
-
Hlavin, E.M.1
Smeaton, M.B.2
Noronha, A.M.3
Wilds, C.J.4
Miller, P.S.5
-
98
-
-
77955868586
-
Translesion DNA synthesis polymerases in DNA interstrand crosslink repair
-
Ho, T. V. & Scharer, O. D. Translesion DNA synthesis polymerases in DNA interstrand crosslink repair. Environ. Mol. Mutagen. 51, 552-566 (2010).
-
(2010)
Environ. Mol. Mutagen.
, vol.51
, pp. 552-566
-
-
Ho, T.V.1
Scharer, O.D.2
-
99
-
-
43849098620
-
The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly
-
Mirchandani, K. D., McCaffrey, R. M. & D'Andrea, A. D. The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly. DNA Repair 7, 902-911 (2008).
-
(2008)
DNA Repair
, vol.7
, pp. 902-911
-
-
Mirchandani, K.D.1
McCaffrey, R.M.2
D'Andrea, A.D.3
-
100
-
-
77949908546
-
Efficacy of neoadjuvant nisplatin in triple-negative breast cancer
-
Silver, D. P. et al. Efficacy of neoadjuvant nisplatin in triple-negative breast cancer. J. Clin. Oncol. 28, 1145-1153 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1145-1153
-
-
Silver, D.P.1
-
101
-
-
0037403380
-
Improved survival in women with BRCA-associated ovarian carcinoma
-
DOI 10.1002/cncr.11310
-
Cass, I. et al. Improved survival in women with BRCA-associated ovarian carcinoma. Cancer 97, 2187-2195 (2003). (Pubitemid 36444059)
-
(2003)
Cancer
, vol.97
, Issue.9
, pp. 2187-2195
-
-
Cass, I.1
Baldwin, R.L.2
Varkey, T.3
Moslehi, R.4
Narod, S.A.5
Karlan, B.Y.6
-
102
-
-
0042317328
-
The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin
-
DOI 10.1074/jbc.C300249200
-
Wu-Baer, F., Lagrazon, K., Yuan, W. & Baer, R. The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin. J. Biol. Chem. 278, 34743-34746 (2003). (Pubitemid 37102231)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.37
, pp. 34743-34746
-
-
Wu-Baer, F.1
Lagrazon, K.2
Yuan, W.3
Baer, R.4
-
103
-
-
77957975815
-
Purified human BRCA2 stimulates RAD51-mediated recombination
-
Jensen, R. B., Carreira, A. & Kowalczykowski, S. C. Purified human BRCA2 stimulates RAD51-mediated recombination. Nature 467, 678-683 (2010).
-
(2010)
Nature
, vol.467
, pp. 678-683
-
-
Jensen, R.B.1
Carreira, A.2
Kowalczykowski, S.C.3
-
104
-
-
77957804604
-
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA
-
Thorslund, T. et al. The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA. Nature Struct. Mol. Biol. 17, 1263-1265 (2010).
-
(2010)
Nature Struct. Mol. Biol.
, vol.17
, pp. 1263-1265
-
-
Thorslund, T.1
-
105
-
-
0034604716
-
The Breast Cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin
-
DOI 10.1074/jbc.C000276200
-
Bhattacharyya, A., Ear, U. S., Koller, B. H., Weichselbaum, R. R. & Bishop, D. K. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of RAD51 and survival following treatment with the DNA cross-linking agent cisplatin. J. Biol. Chem. 275, 23899-23903 (2000). (Pubitemid 30624678)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.31
, pp. 23899-23903
-
-
Bhattacharyya, A.1
Ear, U.S.2
Koller, B.H.3
Weichselbaum, R.R.4
Bishop, D.K.5
-
106
-
-
23344453535
-
Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin
-
DOI 10.1002/jgm.753
-
Ito, M. et al. RAD51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin. J. Gene Med. 7, 1044-1052 (2005). (Pubitemid 41195066)
-
(2005)
Journal of Gene Medicine
, vol.7
, Issue.8
, pp. 1044-1052
-
-
Ito, M.1
Yamamoto, S.2
Nimura, K.3
Hiraoka, K.4
Tamai, K.5
Kaneda, Y.6
-
107
-
-
0038700698
-
Molecular views of recombination proteins and their control
-
DOI 10.1038/nrm1127
-
West, S. C. Molecular views of recombination proteins and their control. Nature Rev. Mol. Cell Biol. 4, 435-445 (2003). (Pubitemid 36648589)
-
(2003)
Nature Reviews Molecular Cell Biology
, vol.4
, Issue.6
, pp. 435-445
-
-
West, S.C.1
-
108
-
-
67650471685
-
Inhibition of poly(ADP-Ribose) polymerase in tumors from BRCA mutation carriers
-
Fong, P. C. et al. Inhibition of poly(ADP-Ribose) polymerase in tumors from BRCA mutation carriers. N. Engl. J. Med. 361, 123-134 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 123-134
-
-
Fong, P.C.1
-
109
-
-
55849133052
-
Remodeling of DNA replication structures by the branch point translocase FANCM
-
Gari, K., Dicaillet, C., Delannoy, M., Wu, L. & Constantinou, A. Remodeling of DNA replication structures by the branch point translocase FANCM. Proc. Natl Acad. Sci. USA 105, 16107-16112 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 16107-16112
-
-
Gari, K.1
Dicaillet, C.2
Delannoy, M.3
Wu, L.4
Constantinou, A.5
-
110
-
-
34447509295
-
Antitumour drugs impede DNA uncoiling by topoisomerase I
-
DOI 10.1038/nature05938, PII NATURE05938
-
Koster, D. A., Palle, K., Bot., E. S., Bjornsti, M. A. & Dekker, N. H. Antitumour drugs impede DNA uncoiling by topoisomerase I. Nature 448, 213-217 (2007). (Pubitemid 47067371)
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 213-217
-
-
Koster, D.A.1
Palle, K.2
Bot, E.S.M.3
Bjornsti, M.-A.4
Dekker, N.H.5
-
111
-
-
0037178740
-
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
-
DOI 10.1126/science.1074023
-
Sogo, J. M., Lopes, M. & Foiani, M. Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 297, 599-602 (2002). (Pubitemid 34815343)
-
(2002)
Science
, vol.297
, Issue.5581
, pp. 599-602
-
-
Sogo, J.M.1
Lopes, M.2
Foiani, M.3
-
112
-
-
78549251695
-
RAD51 protects nascent DNA from MRE11-dependent degradation and promotes continuous DNA synthesis
-
Hashimoto, Y., Chaudhuri, A. R., Lopes, M. & Costanzo, V. RAD51 protects nascent DNA from MRE11-dependent degradation and promotes continuous DNA synthesis. Nature Struct. Mol. Biol. 17, 1305-1311 (2010).
-
(2010)
Nature Struct. Mol. Biol.
, vol.17
, pp. 1305-1311
-
-
Hashimoto, Y.1
Chaudhuri, A.R.2
Lopes, M.3
Costanzo, V.4
-
113
-
-
4744360979
-
2-phase Cells
-
DOI 10.1074/jbc.M405212200
-
Lio, Y. C., Schild, D., Brenneman, M. A., Redpath, J. L. & Chen, D. J. Human RAD51C deficiency destabilizes XRCC3, impairs recombination, and radiosensitizes S/G2-phase cells. J. Biol. Chem. 279, 42313-42320 (2004). (Pubitemid 39313680)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.40
, pp. 42313-42320
-
-
Lio, Y.-C.1
Schild, D.2
Brenneman, M.A.3
Redpath, J.L.4
Chen, D.J.5
-
114
-
-
0037462657
-
Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro
-
DOI 10.1074/jbc.M211038200
-
Lio, Y. C., Mazin, A. V., Kowalczykowski, S. C. & Chen, D. J. Complex formation by the human RAD51B and RAD51C DNA repair proteins and their activities in vitro. J. Biol. Chem. 278, 2469-2478 (2003). (Pubitemid 36801323)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.4
, pp. 2469-2478
-
-
Lio, Y.-C.1
Mazin, A.V.2
Kowalczykowski, S.C.3
Chen, D.J.4
-
115
-
-
77951720395
-
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
-
Meindl, A. et al. Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nature Genet. 42, 410-414 (2010).
-
(2010)
Nature Genet.
, vol.42
, pp. 410-414
-
-
Meindl, A.1
-
116
-
-
0347987856
-
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
-
DOI 10.1038/nature02253
-
Wu, L. & Hickson, I. D. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 426, 870-874 (2003). (Pubitemid 38056876)
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 870-874
-
-
Wu, L.1
Hickson, I.D.2
-
117
-
-
33751426143
-
DNA helicases required for homologous recombination and repair of damaged replication forks
-
DOI 10.1146/annurev.genet.40.110405.090636
-
Wu, L. & Hickson, I. D. DNA helicases required for homologous recombination and repair of damaged replication forks. Annu. Rev. Genet. 40, 279-306 (2006). (Pubitemid 44956787)
-
(2006)
Annual Review of Genetics
, vol.40
, pp. 279-306
-
-
Wu, L.1
Hickson, I.D.2
-
118
-
-
0038642027
-
A multiprotein nuclear complex connects fanconi anemia and bloom syndrome
-
DOI 10.1128/MCB.23.10.3417-3426.2003
-
Meetei, A. R. et al. A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome. Mol. Cell. Biol. 23, 3417-3426 (2003). (Pubitemid 36539175)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.10
, pp. 3417-3426
-
-
Meetei, A.R.1
Sechi, S.2
Wallisch, M.3
Yang, D.4
Young, M.K.5
Joenje, H.6
Hoatlin, M.E.7
Wang, W.8
-
119
-
-
0346351375
-
A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
-
Chaganti, R. S., Schonberg, S. & German, J. A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. Proc. Natl Acad. Sci. USA 71, 4508-4512 (1974).
-
(1974)
Proc. Natl Acad. Sci. USA
, vol.71
, pp. 4508-4512
-
-
Chaganti, R.S.1
Schonberg, S.2
German, J.3
-
120
-
-
0033667704
-
Cancer predisposition caused by elevated mitotic recombination in Bloom mice
-
Luo, G. et al. Cancer predisposition caused by elevated mitotic recombination in Bloom mice. Nature Genet. 26, 424-429 (2000).
-
(2000)
Nature Genet.
, vol.26
, pp. 424-429
-
-
Luo, G.1
-
121
-
-
0019753219
-
Sister chromatid exchange formation
-
Latt, S. A. Sister chromatid exchange formation. Annu. Rev. Genet. 15, 11-55 (1981).
-
(1981)
Annu. Rev. Genet.
, vol.15
, pp. 11-55
-
-
Latt, S.A.1
-
122
-
-
0027397867
-
The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
-
DOI 10.1016/0092-8674(93)90057-W
-
Gottlieb, T. M. & Jackson, S. P. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72, 131-142 (1993). (Pubitemid 23029700)
-
(1993)
Cell
, vol.72
, Issue.1
, pp. 131-142
-
-
Gottlieb, T.M.1
Jackson, S.P.2
-
123
-
-
0042839614
-
Mechanism and regulation of human non-homologous DNA end-joining
-
DOI 10.1038/nrm1202
-
Lieber, M. R., Ma, Y., Pannicke, U. & Schwarz, K. Mechanism and regulation of human non-homologous DNA end-joining. Nature Rev. Mol. Cell Biol. 4, 712-720 (2003). (Pubitemid 37082186)
-
(2003)
Nature Reviews Molecular Cell Biology
, vol.4
, Issue.9
, pp. 712-720
-
-
Lieber, M.R.1
Ma, Y.2
Pannicke, U.3
Schwarz, K.4
-
124
-
-
22144458661
-
Cisplatin-mediated DNA double-strand breaks in replicating but not in quiescent cells of the yeast Saccharomyces cerevisiae
-
DOI 10.1016/j.tox.2005.04.015, PII S0300483X05002064
-
Frankenberg-Schwager, M. et al. Cisplatin-mediated DNA double-strand breaks in replicating but not in quiescent cells of the yeast Saccharomyces cerevisiae. Toxicology 212, 175-184 (2005). (Pubitemid 40981974)
-
(2005)
Toxicology
, vol.212
, Issue.2-3
, pp. 175-184
-
-
Frankenberg-Schwager, M.1
Kirchermeier, D.2
Greif, G.3
Baer, K.4
Becker, M.5
Frankenberg, D.6
-
125
-
-
0027473181
-
Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: A comprehensive survey of genetic and biochemical characteristics
-
DOI 10.1016/0921-8777(93)90062-L
-
Collins, A. R. Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics. Mutat. Res. 293, 99-118 (1993). (Pubitemid 23016403)
-
(1993)
Mutation Research - DNA Repair
, vol.293
, Issue.2
, pp. 99-118
-
-
Collins, A.R.1
-
126
-
-
77953879925
-
Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway
-
Pace, P. et al. Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway. Science 329, 219-223 (2010).
-
(2010)
Science
, vol.329
, pp. 219-223
-
-
Pace, P.1
-
127
-
-
77954310242
-
Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia
-
Adamo, A. et al. Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. Mol. Cell 39, 25-35 (2010).
-
(2010)
Mol. Cell
, vol.39
, pp. 25-35
-
-
Adamo, A.1
-
128
-
-
0035125901
-
cs during murine embryogenesis
-
DOI 10.1016/S0960-9822(01)00048-3
-
Gurley, K. E. & Kemp, C. J. Synthetic lethality between mutation in ATM and DNA-PKcs during murine embryogenesis. Curr. Biol. 11, 191-194 (2001). (Pubitemid 32152105)
-
(2001)
Current Biology
, vol.11
, Issue.3
, pp. 191-194
-
-
Gurley, K.E.1
Kemp, C.J.2
-
129
-
-
4444339506
-
Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle
-
DOI 10.1101/gad.315804
-
Ferreira, M. G. & Cooper, J. P. Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle. Genes Dev. 18, 2249-2254 (2004). (Pubitemid 39209573)
-
(2004)
Genes and Development
, vol.18
, Issue.18
, pp. 2249-2254
-
-
Ferreira, M.G.1
Cooper, J.P.2
-
130
-
-
0035136283
-
Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2
-
Wang, H. et al. Non-homologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2. Cancer Res. 61, 270-277 (2001). (Pubitemid 32095727)
-
(2001)
Cancer Research
, vol.61
, Issue.1
, pp. 270-277
-
-
Wang, H.1
Zeng, Z.-C.2
Bui, T.-A.3
DiBiase, S.J.4
Qin, W.5
Xia, F.6
Powell, S.N.7
Iliakis, G.8
-
131
-
-
67349246802
-
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
-
Yun, M. H. & Hiom, K. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature 459, 460-463 (2009).
-
(2009)
Nature
, vol.459
, pp. 460-463
-
-
Yun, M.H.1
Hiom, K.2
-
132
-
-
0027468265
-
Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks
-
Blier, P. R., Griffith, A. J., Craft, J. & Hardin, J. A. Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks. J. Biol. Chem. 268, 7594-7601 (1993). (Pubitemid 23105662)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.10
, pp. 7594-7601
-
-
Blier, P.R.1
Griffith, A.J.2
Craft, J.3
Hardin, J.A.4
-
133
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting, S. F. et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 141, 243-254 (2010).
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
-
134
-
-
0032930689
-
Erythropoietin addition to granulocyte colony-stimulating factor abrogates life-threatening neutropenia and increases peripheral-blood progenitor-cell mobilization after epirubicin, paclitaxel, and cisplatin combination chemotherapy: Results of a randomized comparison
-
Pierelli, L. et al. Erythropoietin addition to granulocyte colony-stimulating factor abrogates life-threatening neutropenia and increases peripheral-blood progenitor-cell mobilization after epirubicin, paclitaxel, and cisplatin combination chemotherapy: results of a randomized comparison. J. Clin. Oncol. 17, 1288-1295 (1999). (Pubitemid 29162956)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.4
, pp. 1288-1295
-
-
Pierelli, L.1
Perillo, A.2
Greggi, S.3
Salerno, G.4
Benedetti Panici, P.5
Menichella, G.6
Fattorossi, A.7
Leone, G.8
Mancuso, S.9
Scambia, G.10
-
135
-
-
75549083877
-
A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma
-
Locke, F., Clark, J. I. & Gajewski, T. F. A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma. Cancer Chemother. Pharmacol. 65, 509-514 (2010).
-
(2010)
Cancer Chemother. Pharmacol.
, vol.65
, pp. 509-514
-
-
Locke, F.1
Clark, J.I.2
Gajewski, T.F.3
-
136
-
-
58149236959
-
Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells
-
Viale, A. et al. Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells. Nature 457, 51-56 (2009).
-
(2009)
Nature
, vol.457
, pp. 51-56
-
-
Viale, A.1
-
137
-
-
0037444279
-
Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines
-
Selvakumaran, M., Pisarcik, D. A., Bao, R., Yeung, A. T. & Hamilton, T. C. Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines. Cancer Res. 63, 1311-1316 (2003). (Pubitemid 36348710)
-
(2003)
Cancer Research
, vol.63
, Issue.6
, pp. 1311-1316
-
-
Selvakumaran, M.1
Pisarcik, D.A.2
Bao, R.3
Yeung, A.T.4
Hamilton, T.C.5
-
138
-
-
0034333419
-
Increased nucleotide excision repair in cisplatin-resistant ovarian cancer cells: Role of ERCC1-XPF
-
Ferry, K. V., Hamilton, T. C. & Johnson, S. W. Increased nucleotide excision repair in cisplatin-resistant ovarian cancer cells: role of ERCC1-XPF. Biochem. Pharmacol. 60, 1305-1313 (2000).
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 1305-1313
-
-
Ferry, K.V.1
Hamilton, T.C.2
Johnson, S.W.3
-
139
-
-
0038075462
-
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
-
DOI 10.1038/nm852
-
Taniguchi, T. et al. Disruption of the Fanconi anemia- BRCA pathway in cisplatin-sensitive ovarian tumors. Nature Med. 9, 568-574 (2003). (Pubitemid 36597103)
-
(2003)
Nature Medicine
, vol.9
, Issue.5
, pp. 568-574
-
-
Taniguchi, T.1
Tischkowitz, M.2
Ameziane, N.3
Hodgson, S.V.4
Mathew, C.G.5
Joenje, H.6
Mok, S.C.7
D'Andrea, A.D.8
-
140
-
-
0026648940
-
ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients
-
Dabholkar, M. et al. ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients. J. Natl Cancer Inst. 84, 1512-1517 (1992).
-
(1992)
J. Natl Cancer Inst.
, vol.84
, pp. 1512-1517
-
-
Dabholkar, M.1
-
141
-
-
65649122594
-
Functional evidence for EME1 as a marker of cisplatin resistance
-
Tomoda, Y. et al. Functional evidence for EME1 as a marker of cisplatin resistance. Int. J. Cancer 124, 2997-3001 (2009).
-
(2009)
Int. J. Cancer
, vol.124
, pp. 2997-3001
-
-
Tomoda, Y.1
-
142
-
-
0024470560
-
Correlation of resistance to nitrogen mustards in chronic lymphocytic leukemia with enhanced removal of melphalan-induced DNA cross-links
-
DOI 10.1016/0006-2952(89)90025-7
-
Torres-Garcia, S. J., Cousieneau, L., Caplan, S. & Panasci, L. Correlation of resistance to nitrogen mustards in chronic lymphocytic leukemia with enhanced removal of melphalan-induced DNA cross-links. Biochem. Pharmacol. 38, 3122-3123 (1989). (Pubitemid 19222962)
-
(1989)
Biochemical Pharmacology
, vol.38
, Issue.18
, pp. 3122-3123
-
-
Torres-Garcia, S.J.1
Cousineau, L.2
Caplan, S.3
Panasci, L.4
-
143
-
-
0028200221
-
Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells
-
Pietras, R. J. et al. Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells. Oncogene 9, 1829-1838 (1994). (Pubitemid 24194147)
-
(1994)
Oncogene
, vol.9
, Issue.7
, pp. 1829-1838
-
-
Pietras, R.J.1
Fendly, B.M.2
Chazin, V.R.3
Pegram, M.D.4
Howell, S.B.5
Slamon, D.J.6
-
144
-
-
16344371374
-
High-dose alkylating agents with autologous hematopoietic stem cell support and trastuzumab in ERBB2 overexpressing metastatic breast cancer: A feasibility study
-
Goncalves, A. et al. High-dose alkylating agents with autologous hematopoietic stem cell support and trastuzumab in ERBB2 overexpressing metastatic breast cancer: a feasibility study. Anticancer Res. 25, 663-667 (2005). (Pubitemid 40470079)
-
(2005)
Anticancer Research
, vol.25
, Issue.1 B
, pp. 663-667
-
-
Goncalves, A.1
Braud, A.C.2
Viret, F.3
Tarpin, C.4
Charaffe-Jauffret, E.5
Jacquemier, J.6
Maraninchi, D.7
Viens, P.8
-
145
-
-
33646376727
-
Docetaxel, cisplatin, and trastuzumab as primary systemic therapy for human epidermal growth factor receptor 2-positive locally advanced breast cancer
-
DOI 10.1200/JCO.2005.02.8886
-
Hurley, J. et al. Docetaxel, cisplatin, and trastuzumab as primary systemic therapy for human epidermal growth factor receptor 2-positive locally advanced breast cancer. J. Clin. Oncol. 24, 1831-1838 (2006). (Pubitemid 46638980)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.12
, pp. 1831-1838
-
-
Hurley, J.1
Doliny, P.2
Reis, I.3
Silva, O.4
Gomez-Fernandez, C.5
Velez, P.6
Pauletti, G.7
Pegram, M.D.8
Slamon, D.J.9
-
146
-
-
2942691785
-
Results of two open-label, multicenter phase II studies of docetaxel, platinum salts, and trastuzumab in HER2-positive advanced breast cancer
-
Pegram, M. D. et al. Results of two open-label, multicenter phase II studies of docetaxel, platinum salts, and trastuzumab in HER2-positive advanced breast cancer. J. Natl Cancer Inst. 96, 759-769 (2004). (Pubitemid 38771821)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.10
, pp. 759-769
-
-
Pegram, M.D.1
Pienkowski, T.2
Northfelt, D.W.3
Eiermann, W.4
Patel, R.5
Fumoleau, P.6
Quan, E.7
Crown, J.8
Toppmeyer, D.9
Smylie, M.10
Riva, A.11
Blitz, S.12
Press, M.F.13
Reese, D.14
Lindsay, M.-A.15
Slamon, D.J.16
-
147
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
-
DOI 10.1126/science.277.5331.1497
-
Sanchez, Y. et al. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 277, 1497-1501 (1997). (Pubitemid 27449236)
-
(1997)
Science
, vol.277
, Issue.5331
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
148
-
-
2342635919
-
Cell death by mitotic catastrophe: A molecular definition
-
DOI 10.1038/sj.onc.1207528
-
Castedo, M. et al. Cell death by mitotic catastrophe: a molecular definition. Oncogene 23, 2825-2837 (2004). (Pubitemid 38638845)
-
(2004)
Oncogene
, vol.23
, Issue.16 REV. ISS. 2
, pp. 2825-2837
-
-
Castedo, M.1
Perfettini, J.-L.2
Roumier, T.3
Andreau, K.4
Medema, R.5
Kroemer, G.6
-
149
-
-
33846821915
-
P53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage
-
DOI 10.1016/j.ccr.2006.11.024, PII S1535610806003825
-
Reinhardt, H. C., Aslanian, A. S., Lees, J. A. & Yaffe, M. B. p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/ MK2 pathway for survival after DNA damage. Cancer Cell 11, 175-189 (2007). (Pubitemid 46209849)
-
(2007)
Cancer Cell
, vol.11
, Issue.2
, pp. 175-189
-
-
Reinhardt, H.C.1
Aslanian, A.S.2
Lees, J.A.3
Yaffe, M.B.4
-
150
-
-
0035829685
-
Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells
-
DOI 10.1038/sj.onc.1204942
-
Koniaras, K., Cuddihy, A. R., Christopoulos, H., Hogg, A. & O'Connell, M. J. Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells. Oncogene 20, 7453-7463 (2001). (Pubitemid 33086904)
-
(2001)
Oncogene
, vol.20
, Issue.51
, pp. 7453-7463
-
-
Koniaras, K.1
Cuddihy, A.R.2
Christopoulos, H.3
Hogg, A.4
O'Connell, M.J.5
-
151
-
-
0020524876
-
Characterization of the adducts produced in DNA by cis- diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II)
-
Eastman, A. Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II). Biochemistry 22, 3927-3933 (1983). (Pubitemid 13035562)
-
(1983)
Biochemistry
, vol.22
, Issue.16
, pp. 3927-3933
-
-
Eastman, A.1
-
152
-
-
0029585833
-
Solution structure of a cisplatin-induced DNA interstrand cross-link
-
Huang, H., Zhu, L., Reid, B. R., Drobny, G. P. & Hopkins, P. B. Solution structure of a cisplatin-induced DNA interstrand cross-link. Science 270, 1842-1845 (1995). (Pubitemid 26007235)
-
(1995)
Science
, vol.270
, Issue.5243
, pp. 1842-1845
-
-
Huang, H.1
Zhu, L.2
Reid, B.R.3
Drobny, G.P.4
Hopkins, P.B.5
-
153
-
-
0022457418
-
Mechanism of cytotoxicity of anticancer platinum drugs: Evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato) platinum(II) differ only in the kinetics of their interaction with DNA
-
Knox, R. J., Friedlos, F., Lydall, D. A. & Roberts, J. J. Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis- diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato) platinum(II) differ only in the kinetics of their interaction with DNA. Cancer Res. 46, 1972-1979 (1986). (Pubitemid 16080411)
-
(1986)
Cancer Research
, vol.46
, Issue.4
, pp. 1972-1979
-
-
Knox, R.J.1
Friedlos, F.2
Lydall, D.A.3
Roberts, J.J.4
-
154
-
-
9744223515
-
Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherpy for ovarian carcinoma
-
DOI 10.1093/jnci/djh323
-
Vasey, P. A. et al. Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma. J. Natl Cancer Inst. 96, 1682-1691 (2004). (Pubitemid 39585637)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.22
, pp. 1682-1691
-
-
Vasey, P.A.1
Jayson, G.C.2
Gordon, A.3
Gabra, H.4
Coleman, R.5
Atkinson, R.6
Parkin, D.7
Paul, J.8
Hay, A.9
Kaye, S.B.10
-
155
-
-
33746222050
-
Oxaliplatin-related neurotoxicity: How and why?
-
DOI 10.1016/j.critrevonc.2006.01.001, PII S104084280600014X
-
Pasetto, L. M., D'Andrea, M. R., Rossi, E. & Monfardini, S. Oxaliplatin-related neurotoxicity: how and why? Crit. Rev. Oncol. Hematol. 59, 159-168 (2006). (Pubitemid 44094106)
-
(2006)
Critical Reviews in Oncology/Hematology
, vol.59
, Issue.2
, pp. 159-168
-
-
Pasetto, L.M.1
D'Andrea, M.R.2
Rossi, E.3
Monfardini, S.4
-
156
-
-
20944439837
-
Phase III trial of satraplatin, an oral platinum plus prednisone vs. prednisone alone in patients with hormone-refractory prostate cancer
-
DOI 10.1159/000084201
-
Sternberg, C. N. et al. Phase III trial of satraplatin, an oral platinum plus prednisone vs. prednisone alone in patients with hormone-refractory prostate cancer. Oncology 68, 2-9 (2005). (Pubitemid 40675002)
-
(2005)
Oncology
, vol.68
, Issue.1
, pp. 2-9
-
-
Sternberg, C.N.1
Whelan, P.2
Hetherington, J.3
Paluchowska, B.4
Slee, P.H.Th.J.5
Vekemans, K.6
Van Erps, P.7
Theodore, C.8
Koriakine, O.9
Oliver, T.10
Lebwohl, D.11
Debois, M.12
Zurlo, A.13
Collette, L.14
-
157
-
-
70350214379
-
Results of a phase II open-label, nonrandomized trial of oral satraplatin in patients with metastatic breast cancer
-
Smith, J. W. et al. Results of a phase II open-label, nonrandomized trial of oral satraplatin in patients with metastatic breast cancer. Breast Cancer Res. Treat. 118, 361-367 (2009).
-
(2009)
Breast Cancer Res. Treat.
, vol.118
, pp. 361-367
-
-
Smith, J.W.1
-
158
-
-
65349157711
-
Phase II study of picoplatin as second-line therapy for patients with small-cell lung cancer
-
Eckardt, J. R. et al. Phase II study of picoplatin as second-line therapy for patients with small-cell lung cancer. J. Clin. Oncol. 27, 2046-2051 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 2046-2051
-
-
Eckardt, J.R.1
-
159
-
-
0347928863
-
Solution structure of a DNA duplex containing mispair-aligned N4C-ethyl-N4C interstrand cross-linked cytosines
-
Webba da Silva, M. et al. Solution structure of a DNA duplex containing mispair-aligned N4C-ethyl-N4C interstrand cross-linked cytosines. Biochemistry 41, 15181-15188 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 15181-15188
-
-
Webba Da Silva, M.1
-
160
-
-
0014954696
-
Cyclophosphamide-induced cyclical neutropenia. An animal model of a human periodic disease
-
Morley, A. & Stohlman, F. Jr. Cyclophosphamide-induced cyclical neutropenia. An animal model of a human periodic disease. N. Engl. J. Med. 282, 643-646 (1970).
-
(1970)
N. Engl. J. Med.
, vol.282
, pp. 643-646
-
-
Morley, A.1
Stohlman Jr., F.2
-
161
-
-
34848833957
-
Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): A randomised trial
-
DOI 10.1016/S0140-6736(07)61537-2, PII S0140673607615372
-
Facon, T. et al. Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet 370, 1209-1218 (2007). (Pubitemid 47516593)
-
(2007)
Lancet
, vol.370
, Issue.9594
, pp. 1209-1218
-
-
Facon, T.1
Mary, J.Y.2
Hulin, C.3
Benboubker, L.4
Attal, M.5
Pegourie, B.6
Renaud, M.7
Harousseau, J.L.8
Guillerm, G.9
Chaleteix, C.10
Dib, M.11
Voillat, L.12
Maisonneuve, H.13
Troncy, J.14
Dorvaux, V.15
Monconduit, M.16
Martin, C.17
Casassus, P.18
Jaubert, J.19
Jardel, H.20
Doyen, C.21
Kolb, B.22
Anglaret, B.23
Grosbois, B.24
Yakoub-Agha, I.25
Mathiot, C.26
Avet-Loiseau, H.27
more..
-
162
-
-
0034649696
-
Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia
-
Rai, K. R. et al. Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia. N. Engl. J. Med. 343, 1750-1757 (2000).
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1750-1757
-
-
Rai, K.R.1
-
163
-
-
0034442745
-
Effect of vinorelbine, ifosfamide, and cisplatin combination chemotherapy in advanced non-small-cell lung cancer
-
Ahn, J. B. et al. Effect of vinorelbine, ifosfamide, and cisplatin combination chemotherapy in advanced non-small-cell lung cancer. Am. J. Clin. Oncol. 23, 622-628 (2000).
-
(2000)
Am. J. Clin. Oncol.
, vol.23
, pp. 622-628
-
-
Ahn, J.B.1
-
164
-
-
0028801257
-
Solution structures of psoralen monoadducted and cross-linked DNA oligomers by NMR spectroscopy and restrained molecular dynamics
-
Spielmann, H. P., Dwyer, T. J., Hearst, J. E. & Wemmer, D. E. Solution structures of psoralen monoadducted and cross-linked DNA oligomers by NMR spectroscopy and restrained molecular dynamics. Biochemistry 34, 12937-12953 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 12937-12953
-
-
Spielmann, H.P.1
Dwyer, T.J.2
Hearst, J.E.3
Wemmer, D.E.4
-
165
-
-
0022246321
-
Hematologic toxicity of cisplatin and mitomycin in combination for squamous cell carcinoma of esophagus
-
Stoll, D. B., Lavin, P. T. & Engstrom, P. F. Hematologic toxicity of cisplatin and mitomycin in combination for squamous cell carcinoma of esophagus. Am. J. Clin. Oncol. 8, 231-234 (1985). (Pubitemid 16256998)
-
(1985)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.8
, Issue.3
, pp. 231-234
-
-
Stoll, D.B.1
Lavin, P.T.2
Engstrom, P.F.3
-
166
-
-
3042706114
-
Long-term results of a phase II study of synchronous chemoradiotherapy in advanced muscle invasive bladder cancer
-
Hussain, S. A. et al. Long-term results of a phase II study of synchronous chemoradiotherapy in advanced muscle invasive bladder cancer. Br. J. Cancer 90, 2106-2111 (2004). (Pubitemid 38869713)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.11
, pp. 2106-2111
-
-
Hussain, S.A.1
Stocken, D.D.2
Peake, D.R.3
Glaholm, J.G.4
Zarkar, A.5
Wallace, D.M.A.6
James, N.D.7
-
167
-
-
0025306997
-
Side-effects of psoralen photochemotherapy (PUVA)
-
Wolff, K. Side-effects of psoralen photochemotherapy (PUVA). Br. J. Dermatol. 122, 117-125 (1990). (Pubitemid 20176070)
-
(1990)
British Journal of Dermatology
, vol.122
, Issue.SUPPL. 36
, pp. 117-125
-
-
Wolff, K.1
-
168
-
-
14944378170
-
Long-term follow-up of patients with early-stage cutaneous T-cell lymphoma who achieved complete remission with psoralen plus UV-A monotherapy
-
DOI 10.1001/archderm.141.3.305
-
Querfeld, C. et al. Long-term follow-up of patients with early-stage cutaneous T-cell lymphoma who achieved complete remission with psoralen plus UV-A monotherapy. Arch. Dermatol. 141, 305-311 (2005). (Pubitemid 40365446)
-
(2005)
Archives of Dermatology
, vol.141
, Issue.3
, pp. 305-311
-
-
Querfeld, C.1
Rosen, S.T.2
Kuzel, T.M.3
Kirby, K.A.4
Roenigk Jr., H.H.5
Prinz, B.M.6
Guitart, J.7
-
169
-
-
77649192721
-
A phase i trial of SJG-136 (NSC#694501) in advanced solid tumors
-
Janjigian, Y. Y. et al. A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors. Cancer Chemother. Pharmacol. 65, 833-838 (2010).
-
(2010)
Cancer Chemother. Pharmacol.
, vol.65
, pp. 833-838
-
-
Janjigian, Y.Y.1
|