The Fanconi anemia pathway limits the severity of mutagenesis

DNA Repair

Volumn 5, Issue 8, 2006, Pages 875-884

  Hinz, John M ^a   Nham, Peter B ^a   Salazar, Edmund P ^a   Thompson, Larry H ^a  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

DNA double strand breaks; DNA replication forks; Homologous recombinational repair; Nonhomologous end joining; Spontaneous mutation rate

Indexed keywords

FANCONI ANEMIA PROTEIN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTAGENIC AGENT; PROTEIN; UNCLASSIFIED DRUG;

CELL MUTANT; CHO CELL; CHROMOSOME DISORDER; CHROMOSOME REARRANGEMENT; DATA ANALYSIS; DISEASE SEVERITY; DNA DAMAGE; DNA REPLICATION; DNA STRAND BREAKAGE; DNA SYNTHESIS; FANCONI ANEMIA; GENE DELETION; GENE LOCUS; GENE TRANSLOCATION; HOMOLOGOUS RECOMBINATION; HUMAN; LETHALITY; MEDICAL LITERATURE; MUTAGENESIS; NONHUMAN; OUTCOME ASSESSMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; X CHROMOSOME;

ANIMALS; CHO CELLS; CHROMOSOMAL INSTABILITY; CRICETINAE; CRICETULUS; DNA DAMAGE; DNA REPAIR; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MODELS, GENETIC; MUTAGENESIS; MUTAGENS;

CRICETINAE;

EID: 33746503650     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2006.05.039     Document Type: Review

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