The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks

EMBO Journal

Volumn 25, Issue 20, 2006, Pages 4921-4932

  Hanada, Katsuhiro ^a   Budzowska, Magda ^a   Modesti, Mauro ^a   Maas, Alex ^a   Wyman, Claire ^a   Essers, Jeroen ^a   Kanaar, Roland ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Homologous recombination; Interstrand crosslink; Rad54; Stalled replication forks; Structure specific endonucleases

Indexed keywords

DOUBLE STRANDED DNA; ENDONUCLEASE; ENDONUCLEASE MUS81; RAD54 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA CLEAVAGE; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND; DNA STRAND BREAKAGE; EMBRYO; EMBRYONIC STEM CELL; ENZYME SPECIFICITY; ENZYME STRUCTURE; HOMOLOGOUS RECOMBINATION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION;

ANIMALS; CELLS, CULTURED; DNA BREAKS, DOUBLE-STRANDED; DNA HELICASES; DNA REPAIR; DNA REPLICATION; DNA-BINDING PROTEINS; EMBRYO; EMBRYO, MAMMALIAN; ENDODEOXYRIBONUCLEASES; ENDONUCLEASES; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; RECOMBINATION, GENETIC; S PHASE; STEM CELLS;

EID: 33750206776     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601344     Document Type: Article

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