Identification of the allosteric regulatory site of insulysin

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Noinaj, Nicholas ^a   Bhasin, Sonia K ^a   Song, Eun Suk ^a   Scoggin, Kirsten E ^a   Juliano, Maria A ^b   Juliano, Luiz ^b   Hersh, Louis B ^a   Rodgers, David W ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; INSULINASE; ISOLEUCINE; PHENYLALANINE; SERINE; TYROSINE; VALINE; 2',3' O (2,4,6 TRINITRO CYCLOHEXADIENYLIDINE)ADENOSINE 5' TRIPHOSPHATE; 2',3'-O-(2,4,6-TRINITRO-CYCLOHEXADIENYLIDINE)ADENOSINE 5'-TRIPHOSPHATE; DRUG DERIVATIVE; LIGAND; MUTANT PROTEIN;

ALLOSTERISM; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HYDROGEN BOND; LIGAND BINDING; NONHUMAN; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; PROTEIN DOMAIN; RAT; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; KINETICS; MASS SPECTROMETRY; METABOLISM; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; SPECTROFLUOROMETRY; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; INSULYSIN; KINETICS; LIGANDS; MASS SPECTROMETRY; MODELS, MOLECULAR; MUTANT PROTEINS; MUTATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; RATS; SPECTROMETRY, FLUORESCENCE;

EID: 79959605950     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020864     Document Type: Article

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