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Volumn 1249, Issue , 2009, Pages 1-8

Promoter polymorphisms which modulate insulin degrading enzyme expression may increase susceptibility to Alzheimer's disease

Author keywords

Alzheimer's disease; IDE; Polymorphism; Promoter

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; INSULINASE; LUCIFERASE;

EID: 58149170562     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.10.034     Document Type: Article
Times cited : (25)

References (47)
  • 2
    • 3242777669 scopus 로고    scopus 로고
    • Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese
    • Bian L., Yang J.D., Guo T.W., Sun Y., Duan S.W., Chen W.Y., Pan Y.X., Feng G.Y., and He L. Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese. Neurology 63 (2004) 241-245
    • (2004) Neurology , vol.63 , pp. 241-245
    • Bian, L.1    Yang, J.D.2    Guo, T.W.3    Sun, Y.4    Duan, S.W.5    Chen, W.Y.6    Pan, Y.X.7    Feng, G.Y.8    He, L.9
  • 3
    • 0034711206 scopus 로고    scopus 로고
    • Degradation of amylin by insulin-degrading enzyme
    • Bennett R.G., Duckworth W.C., and Hamel F.G. Degradation of amylin by insulin-degrading enzyme. J. Biol. Chem. 275 (2000) 36621-36625
    • (2000) J. Biol. Chem. , vol.275 , pp. 36621-36625
    • Bennett, R.G.1    Duckworth, W.C.2    Hamel, F.G.3
  • 5
    • 0037162647 scopus 로고    scopus 로고
    • Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease
    • Boussaha M., Hannequin D., Verpillat P., Brice A., Frebourg T., and Campion D. Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease. Neurosci. Lett. 329 (2002) 121-123
    • (2002) Neurosci. Lett. , vol.329 , pp. 121-123
    • Boussaha, M.1    Hannequin, D.2    Verpillat, P.3    Brice, A.4    Frebourg, T.5    Campion, D.6
  • 6
  • 8
    • 0029162472 scopus 로고
    • Transcriptional activation of Alzheimer's beta-amyloid precursor protein gene by stress
    • Dewji N.N., Do C., and Bayney R.M. Transcriptional activation of Alzheimer's beta-amyloid precursor protein gene by stress. Brain Res. Mol. Brain Res. 33 (1995) 245-253
    • (1995) Brain Res. Mol. Brain Res. , vol.33 , pp. 245-253
    • Dewji, N.N.1    Do, C.2    Bayney, R.M.3
  • 9
    • 4143134071 scopus 로고    scopus 로고
    • Insulin-degrading enzyme, apolipoprotein E, and Alzheimer's disease
    • Edland S.D. Insulin-degrading enzyme, apolipoprotein E, and Alzheimer's disease. J. Mol. Neurosci. 23 (2004) 213-217
    • (2004) J. Mol. Neurosci. , vol.23 , pp. 213-217
    • Edland, S.D.1
  • 10
    • 0038519618 scopus 로고    scopus 로고
    • Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE)
    • Edland S.D., Wavrant-DeVriesé F., Compton D., Smith G.E., Ivnik R., Boeve B.F., Tangalos E.G., and Petersen R.C. Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE). Neurosci. Lett. 345 (2003) 21-24
    • (2003) Neurosci. Lett. , vol.345 , pp. 21-24
    • Edland, S.D.1    Wavrant-DeVriesé, F.2    Compton, D.3    Smith, G.E.4    Ivnik, R.5    Boeve, B.F.6    Tangalos, E.G.7    Petersen, R.C.8
  • 11
    • 1842765688 scopus 로고    scopus 로고
    • Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease
    • Ertekin-Taner N., Allen M., Fadale D., Scanlin L., Younkin L., Petersen R.C., Graff-Radford N., and Younkin S.G. Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease. Hum. Mutat. 23 (2004) 334-342
    • (2004) Hum. Mutat. , vol.23 , pp. 334-342
    • Ertekin-Taner, N.1    Allen, M.2    Fadale, D.3    Scanlin, L.4    Younkin, L.5    Petersen, R.C.6    Graff-Radford, N.7    Younkin, S.G.8
  • 13
    • 1642290835 scopus 로고    scopus 로고
    • Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein
    • Farris W., Mansourian S., Leissring M.A., Eckman E.A., Bertram L., Eckman C.B., Tanzi R.E., and Selkoe D.J. Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am. J. Pathol. 164 (2004) 1425-1434
    • (2004) Am. J. Pathol. , vol.164 , pp. 1425-1434
    • Farris, W.1    Mansourian, S.2    Leissring, M.A.3    Eckman, E.A.4    Bertram, L.5    Eckman, C.B.6    Tanzi, R.E.7    Selkoe, D.J.8
  • 14
    • 21444432879 scopus 로고    scopus 로고
    • Mutation screening of a haplotype block around the insulin degrading enzyme gene and association with Alzheimer's disease
    • Feuk L., McCarthy S., Andersson B., Prince J.A., and Brookes A.J. Mutation screening of a haplotype block around the insulin degrading enzyme gene and association with Alzheimer's disease. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 136 (2005) 69-71
    • (2005) Am. J. Med. Genet. B. Neuropsychiatr. Genet. , vol.136 , pp. 69-71
    • Feuk, L.1    McCarthy, S.2    Andersson, B.3    Prince, J.A.4    Brookes, A.J.5
  • 15
  • 16
    • 13144306087 scopus 로고    scopus 로고
    • Amyloid precursor protein (APP) and its derivatives change after cellular energy depletion. An in vitro-study
    • Hoyer A., Bardenheuer H.J., Martin E., and Plaschke K. Amyloid precursor protein (APP) and its derivatives change after cellular energy depletion. An in vitro-study. J. Neural. Transm. 112 (2005) 239-253
    • (2005) J. Neural. Transm. , vol.112 , pp. 239-253
    • Hoyer, A.1    Bardenheuer, H.J.2    Martin, E.3    Plaschke, K.4
  • 17
    • 0021111565 scopus 로고
    • A high molecular weight metalloendoprotease from the cytosol of mammalian cells
    • Kirschner R.J., and Goldberg A.L. A high molecular weight metalloendoprotease from the cytosol of mammalian cells. J. Biol. Chem. 258 (1983) 967-976
    • (1983) J. Biol. Chem. , vol.258 , pp. 967-976
    • Kirschner, R.J.1    Goldberg, A.L.2
  • 18
    • 0027452730 scopus 로고
    • Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues
    • Kuo W.L., Montag A.G., and Rosner M.R. Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues. Endocrinology 132 (1993) 604-611
    • (1993) Endocrinology , vol.132 , pp. 604-611
    • Kuo, W.L.1    Montag, A.G.2    Rosner, M.R.3
  • 19
    • 0028176821 scopus 로고
    • Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
    • Kurochkin I.V., and Goto S. Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS. Lett. 345 (1994) 33-37
    • (1994) FEBS. Lett. , vol.345 , pp. 33-37
    • Kurochkin, I.V.1    Goto, S.2
  • 20
    • 0035399887 scopus 로고    scopus 로고
    • Insulin-degrading enzyme: embarking on amyloid destruction
    • Kurochkin I.V. Insulin-degrading enzyme: embarking on amyloid destruction. Trends Biochem. Sci. 26 (2001) 421-425
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 421-425
    • Kurochkin, I.V.1
  • 21
    • 1342347850 scopus 로고    scopus 로고
    • A proximal gene promoter region for the beta-amyloid precursor protein provides a link between development, apoptosis, and Alzheimer's disease
    • Lahiri D.K., Ghosh C., and Ge Y.W. A proximal gene promoter region for the beta-amyloid precursor protein provides a link between development, apoptosis, and Alzheimer's disease. Ann. N. Y. Acad. Sci. 1010 (2003) 643-647
    • (2003) Ann. N. Y. Acad. Sci. , vol.1010 , pp. 643-647
    • Lahiri, D.K.1    Ghosh, C.2    Ge, Y.W.3
  • 22
    • 0346101885 scopus 로고    scopus 로고
    • Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death
    • Leissring M.A., Farris W., Chang A.Y., Walsh D.M., Wu X., Sun X., Frosch M.P., and Selkoe D.J. Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron 40 (2003) 1087-1093
    • (2003) Neuron , vol.40 , pp. 1087-1093
    • Leissring, M.A.1    Farris, W.2    Chang, A.Y.3    Walsh, D.M.4    Wu, X.5    Sun, X.6    Frosch, M.P.7    Selkoe, D.J.8
  • 23
    • 0038343343 scopus 로고    scopus 로고
    • Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease
    • Ling Y., Morgan K., and Kalsheker N. Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease. Int. J. Biochem. Cell Biol. 35 (2003) 1505-1535
    • (2003) Int. J. Biochem. Cell Biol. , vol.35 , pp. 1505-1535
    • Ling, Y.1    Morgan, K.2    Kalsheker, N.3
  • 24
    • 37549040895 scopus 로고    scopus 로고
    • Promoter polymorphisms which modulate APP expression may increase susceptibility to Alzheimer's disease
    • Lv H., Jia L., and Jia J. Promoter polymorphisms which modulate APP expression may increase susceptibility to Alzheimer's disease. Neurobiol. Aging 29 (2008) 194-202
    • (2008) Neurobiol. Aging , vol.29 , pp. 194-202
    • Lv, H.1    Jia, L.2    Jia, J.3
  • 25
    • 0031044352 scopus 로고    scopus 로고
    • Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme
    • McDermott J.R., and Gibson A.M. Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme. Neurochem. Res. 22 (1997) 49-56
    • (1997) Neurochem. Res. , vol.22 , pp. 49-56
    • McDermott, J.R.1    Gibson, A.M.2
  • 27
    • 0024595382 scopus 로고
    • Degradation of insulin and insulin-like growth factors by enzyme purified from human erythrocytes. Comparison of degradation products observed with A14-and B26-[125I] monoiodoinsulin
    • Misbin R.I., and Almira E.C. Degradation of insulin and insulin-like growth factors by enzyme purified from human erythrocytes. Comparison of degradation products observed with A14-and B26-[125I] monoiodoinsulin. Diabetes 38 (1989) 152-158
    • (1989) Diabetes , vol.38 , pp. 152-158
    • Misbin, R.I.1    Almira, E.C.2
  • 28
    • 0034551718 scopus 로고    scopus 로고
    • Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques
    • Mukherjee A., Song E., Kihiko-Ehmann M., Goodman J.P.J., Pyrek J.S., Estus S., and Hersh L.B. Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques. J. Neurosci. 20 (2000) 8745-8749
    • (2000) J. Neurosci. , vol.20 , pp. 8745-8749
    • Mukherjee, A.1    Song, E.2    Kihiko-Ehmann, M.3    Goodman, J.P.J.4    Pyrek, J.S.5    Estus, S.6    Hersh, L.B.7
  • 29
    • 0034895326 scopus 로고    scopus 로고
    • The genetics of late-onset Alzheimer's disease
    • Myers A.J., and Goate A.M. The genetics of late-onset Alzheimer's disease. Curr. Opin. Neurol. 14 (2001) 433-440
    • (2001) Curr. Opin. Neurol. , vol.14 , pp. 433-440
    • Myers, A.J.1    Goate, A.M.2
  • 31
    • 0026527618 scopus 로고
    • Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver
    • Ogawa W., Shii K., Yonezawa K., Baba S., and Yokono K. Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver. J. Biol. Chem. 267 (1992) 1310-1316
    • (1992) J. Biol. Chem. , vol.267 , pp. 1310-1316
    • Ogawa, W.1    Shii, K.2    Yonezawa, K.3    Baba, S.4    Yokono, K.5
  • 32
    • 0034038036 scopus 로고    scopus 로고
    • Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains
    • Pérez A., Morelli L., Cresto J.C., and Castaño E.M. Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains. Neurochem. Res. 25 (2000) 247-255
    • (2000) Neurochem. Res. , vol.25 , pp. 247-255
    • Pérez, A.1    Morelli, L.2    Cresto, J.C.3    Castaño, E.M.4
  • 34
    • 29844432266 scopus 로고    scopus 로고
    • Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis
    • Qiu W.Q., and Folstein M.F. Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis. Neurobiol. Aging 27 (2006) 190-198
    • (2006) Neurobiol. Aging , vol.27 , pp. 190-198
    • Qiu, W.Q.1    Folstein, M.F.2
  • 35
    • 1842367306 scopus 로고    scopus 로고
    • Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells
    • Qiu W.Q., Ye Z., Kholodenko D., Seubert P., and Selkoe D.J. Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells. J. Biol. Chem. 272 (1997) 6641-6646
    • (1997) J. Biol. Chem. , vol.272 , pp. 6641-6646
    • Qiu, W.Q.1    Ye, Z.2    Kholodenko, D.3    Seubert, P.4    Selkoe, D.J.5
  • 37
    • 3442881114 scopus 로고    scopus 로고
    • Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury
    • Olsson A., Csajbok L., Ost M., Höglund K., Nylén K., Rosengren L., Nellgård B., and Blennow K. Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury. J. Neurol. 251 (2004) 870-876
    • (2004) J. Neurol. , vol.251 , pp. 870-876
    • Olsson, A.1    Csajbok, L.2    Ost, M.3    Höglund, K.4    Nylén, K.5    Rosengren, L.6    Nellgård, B.7    Blennow, K.8
  • 39
    • 27844468150 scopus 로고    scopus 로고
    • Bovine prion protein gene (PRNP) promoter polymorphisms modulate PRNP expression and may be responsible for differences in bovine spongiform encephalopathy susceptibility
    • Sander P., Hamann H., Drögemüller C., Kashkevich K., Schiebel K., and Leeb T. Bovine prion protein gene (PRNP) promoter polymorphisms modulate PRNP expression and may be responsible for differences in bovine spongiform encephalopathy susceptibility. J. Biol. Chem. 280 (2005) 37408-37414
    • (2005) J. Biol. Chem. , vol.280 , pp. 37408-37414
    • Sander, P.1    Hamann, H.2    Drögemüller, C.3    Kashkevich, K.4    Schiebel, K.5    Leeb, T.6
  • 40
    • 0037192120 scopus 로고    scopus 로고
    • Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and-insoluble pools in CHO-695 cells
    • Sudoh S., Frosch M.P., and Wolf B.A. Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and-insoluble pools in CHO-695 cells. Biochemistry 41 (2002) 1091-1099
    • (2002) Biochemistry , vol.41 , pp. 1091-1099
    • Sudoh, S.1    Frosch, M.P.2    Wolf, B.A.3
  • 41
    • 27744542593 scopus 로고    scopus 로고
    • Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia
    • Tabner B.J., El-Agnaf O.M., Turnbull S., German M.J., Paleologou K.E., Hayashi Y., Cooper L.J., Fullwood N.J., and Allsop D. Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia. J. Biol. Chem. 280 (2005) 35789-35792
    • (2005) J. Biol. Chem. , vol.280 , pp. 35789-35792
    • Tabner, B.J.1    El-Agnaf, O.M.2    Turnbull, S.3    German, M.J.4    Paleologou, K.E.5    Hayashi, Y.6    Cooper, L.J.7    Fullwood, N.J.8    Allsop, D.9
  • 42
    • 0035950188 scopus 로고    scopus 로고
    • New frontiers in Alzheimer's disease genetics
    • Tanzi R.E., and Bertram L. New frontiers in Alzheimer's disease genetics. Neuron 32 (2001) 181-184
    • (2001) Neuron , vol.32 , pp. 181-184
    • Tanzi, R.E.1    Bertram, L.2
  • 44
    • 0034161516 scopus 로고    scopus 로고
    • Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme
    • Vekrellis K., Ye Z., Qiu W.Q., Walsh D., Hartley D., Chesneau V., Rosner M.R., and Selkoe D.J. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J. Neurosci. 20 (2000) 1657-1665
    • (2000) J. Neurosci. , vol.20 , pp. 1657-1665
    • Vekrellis, K.1    Ye, Z.2    Qiu, W.Q.3    Walsh, D.4    Hartley, D.5    Chesneau, V.6    Rosner, M.R.7    Selkoe, D.J.8
  • 47
    • 0033528263 scopus 로고    scopus 로고
    • Effects of hypoxia induced by Na2S2O4 on intracellular calcium and resting potential of mouse glomus cells
    • Zhang X.Q., and Eyzaguirre C. Effects of hypoxia induced by Na2S2O4 on intracellular calcium and resting potential of mouse glomus cells. Brain Res. 818 (1999) 118-126
    • (1999) Brain Res. , vol.818 , pp. 118-126
    • Zhang, X.Q.1    Eyzaguirre, C.2


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