-
1
-
-
0019540474
-
Insulin metabolism and degradation
-
Duckworth WC, Kitabchi AE 1981 Insulin metabolism and degradation. Endocr Rev 2:210-233
-
(1981)
Endocr Rev
, vol.2
, pp. 210-233
-
-
Duckworth, W.C.1
Kitabchi, A.E.2
-
2
-
-
0024062933
-
Insulin degradation: Mechanisms, products, and significance
-
Duckworth WC 1988 Insulin degradation: mechanisms, products, and significance. Endocr Rev 9:319-345
-
(1988)
Endocr Rev
, vol.9
, pp. 319-345
-
-
Duckworth, W.C.1
-
3
-
-
0031062399
-
The significance of intracellular insulin to insulin action
-
Duckworth WC, Bennett RG, Hamel FG 1997 The significance of intracellular insulin to insulin action. J Invest Med 45:20-27
-
(1997)
J Invest Med
, vol.45
, pp. 20-27
-
-
Duckworth, W.C.1
Bennett, R.G.2
Hamel, F.G.3
-
4
-
-
0022461393
-
The reversible receptor binding of insulin in isolated rat adipocytes measured at 37 degrees: The binding is not rate limiting for cellular uptake
-
Sonne O 1986 The reversible receptor binding of insulin in isolated rat adipocytes measured at 37 degrees: the binding is not rate limiting for cellular uptake. Biochim Biophys Acta 886:302-309
-
(1986)
Biochim Biophys Acta
, vol.886
, pp. 302-309
-
-
Sonne, O.1
-
5
-
-
0029147069
-
Rat insulin turnover in vivo
-
Canas X, Fernandez-Lopez JA, Ardevol A, Adan C, Esteve M, Rafecas I, Remesar X, Alemany M 1995 Rat insulin turnover in vivo. Endocrinology 136:3871-3876
-
(1995)
Endocrinology
, vol.136
, pp. 3871-3876
-
-
Canas, X.1
Fernandez-Lopez, J.A.2
Ardevol, A.3
Adan, C.4
Esteve, M.5
Rafecas, I.6
Remesar, X.7
Alemany, M.8
-
7
-
-
0026786254
-
Posthepatic rate of appearance of insulin: Measurement and validation in the non-steady state
-
Morishima T, Pye S, Bradshaw C, Radziuk J 1992 Posthepatic rate of appearance of insulin: measurement and validation in the non-steady state. Am J Physiol 263:E772-E779
-
(1992)
Am J Physiol
, vol.263
-
-
Morishima, T.1
Pye, S.2
Bradshaw, C.3
Radziuk, J.4
-
8
-
-
0027179311
-
Five-compartment model of insulin kinetics and its use to investigate action of chloroquine in NIDDM
-
Hovorka R, Powrie JK, Smith GD, Sonksen PH, Carson ER, Jones RH 1993 Five-compartment model of insulin kinetics and its use to investigate action of chloroquine in NIDDM. Am J Physiol 265: E162-E175
-
(1993)
Am J Physiol
, vol.265
-
-
Hovorka, R.1
Powrie, J.K.2
Smith, G.D.3
Sonksen, P.H.4
Carson, E.R.5
Jones, R.H.6
-
9
-
-
7844235637
-
Insulin degradation and insulin degrading enzyme
-
Jefferson LS (ed) Oxford University Press, New York, in press
-
Duckworth WC, Hamel FG, Insulin degradation and insulin degrading enzyme. In: Jefferson LS (ed) The Handbook of Physiology, The Endocrine Pancreas and Regulation of Metabolism. Oxford University Press, New York, in press
-
The Handbook of Physiology, the Endocrine Pancreas and Regulation of Metabolism
-
-
Duckworth, W.C.1
Hamel, F.G.2
-
10
-
-
0025864656
-
Receptor-recycling model of clearance and distribution of insulin in the perfused mouse liver
-
Sato H, Terasaki T, Mizuguchi H, Okumura K, Tsuji A 1991 Receptor-recycling model of clearance and distribution of insulin in the perfused mouse liver. Diabetologia 34:613-621
-
(1991)
Diabetologia
, vol.34
, pp. 613-621
-
-
Sato, H.1
Terasaki, T.2
Mizuguchi, H.3
Okumura, K.4
Tsuji, A.5
-
12
-
-
0024851306
-
Kinetics of insulin internalization and processing in adipocytes: Effects of insulin concentration
-
Jochen A, Hays J, Lee M 1989 Kinetics of insulin internalization and processing in adipocytes: effects of insulin concentration. J Cell Physiol 141:527-534
-
(1989)
J Cell Physiol
, vol.141
, pp. 527-534
-
-
Jochen, A.1
Hays, J.2
Lee, M.3
-
13
-
-
0019405996
-
Insulin degradation by hepatocytes in primary culture
-
Duckworth WC, Runyan K, Wright RK, Halban PA, Solomon SS 1981 Insulin degradation by hepatocytes in primary culture. Endocrinology 108:1142-1147
-
(1981)
Endocrinology
, vol.108
, pp. 1142-1147
-
-
Duckworth, W.C.1
Runyan, K.2
Wright, R.K.3
Halban, P.A.4
Solomon, S.S.5
-
14
-
-
0028144531
-
Insulin degradation in vitro and in vivo: A comparative study in men. Evidence that immunoprecipitable, partially rebindable degradation products are released from cells and circulate in blood
-
Benzi L, Cecchetti P, Ciccarone A, Pilo A, Di Cianni G, Navalesi R 1994 Insulin degradation in vitro and in vivo: a comparative study in men. Evidence that immunoprecipitable, partially rebindable degradation products are released from cells and circulate in blood. Diabetes 43:297-304
-
(1994)
Diabetes
, vol.43
, pp. 297-304
-
-
Benzi, L.1
Cecchetti, P.2
Ciccarone, A.3
Pilo, A.4
Di Cianni, G.5
Navalesi, R.6
-
15
-
-
0015425490
-
Release of immunoreactive insulin from the human heart
-
Wahlqvist ML, Kaijser L, Lassers BW, Low H, Carlson LA 1972 Release of immunoreactive insulin from the human heart. Eur J Clin Invest 2:407-411
-
(1972)
Eur J Clin Invest
, vol.2
, pp. 407-411
-
-
Wahlqvist, M.L.1
Kaijser, L.2
Lassers, B.W.3
Low, H.4
Carlson, L.A.5
-
16
-
-
0031032274
-
Effects of free fatty acids and glucose on splanchnic insulin dynamics
-
Hennes MM, Dua A, Kissebah AH 1997 Effects of free fatty acids and glucose on splanchnic insulin dynamics. Diabetes 46:57-62
-
(1997)
Diabetes
, vol.46
, pp. 57-62
-
-
Hennes, M.M.1
Dua, A.2
Kissebah, A.H.3
-
17
-
-
0029942373
-
Effect of lactate on hepatic insulin clearance in perfused rat liver
-
Pagano C, Rizzato M, Lombardi AM, Fabris R, Favaro A, Federspil G, Vettor R 1996 Effect of lactate on hepatic insulin clearance in perfused rat liver. Am J Physiol 270:R682-R687
-
(1996)
Am J Physiol
, vol.270
-
-
Pagano, C.1
Rizzato, M.2
Lombardi, A.M.3
Fabris, R.4
Favaro, A.5
Federspil, G.6
Vettor, R.7
-
18
-
-
0025296906
-
Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes
-
Svedberg J, Bjorntorp P, Smith U, Lonnroth P 1990 Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes. Diabetes 39:570-574
-
(1990)
Diabetes
, vol.39
, pp. 570-574
-
-
Svedberg, J.1
Bjorntorp, P.2
Smith, U.3
Lonnroth, P.4
-
19
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G 1997 Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46:3-10
-
(1997)
Diabetes
, vol.46
, pp. 3-10
-
-
Boden, G.1
-
20
-
-
0020539930
-
Decreased hepatic insulin extraction in subjects with mild glucose interolerance
-
Bonora E, Zavaroni I, Coscelli C, Butturini U 1983 Decreased hepatic insulin extraction in subjects with mild glucose interolerance. Metabolism 32:438-446
-
(1983)
Metabolism
, vol.32
, pp. 438-446
-
-
Bonora, E.1
Zavaroni, I.2
Coscelli, C.3
Butturini, U.4
-
21
-
-
0022860890
-
Further evidence that insulin metabolism is a major determinant of peripheral insulin response to oral glucose in subjects with mild glucose intolerance
-
Bonora E, Zavaroni I, Manicardi V, Coscelli C, Butturini U 1986 Further evidence that insulin metabolism is a major determinant of peripheral insulin response to oral glucose in subjects with mild glucose intolerance. J Endocrinol Invest 9:371-374
-
(1986)
J Endocrinol Invest
, vol.9
, pp. 371-374
-
-
Bonora, E.1
Zavaroni, I.2
Manicardi, V.3
Coscelli, C.4
Butturini, U.5
-
23
-
-
0031154101
-
Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals
-
Jones CN, Pei D, Staris P, Polonsky KS, Chen YD, Reaven GM 1997 Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals. J Clin Endocrinol Metab 82:1834-1838
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 1834-1838
-
-
Jones, C.N.1
Pei, D.2
Staris, P.3
Polonsky, K.S.4
Chen, Y.D.5
Reaven, G.M.6
-
24
-
-
0024355499
-
Defects in insulin-receptor internalization and processing in monocytes of obese subjects and obese NIDDM patients
-
Trischitta V, Brunetti A, Chiavetta A, Benzi L, Papa V, Vigneri R 1989 Defects in insulin-receptor internalization and processing in monocytes of obese subjects and obese NIDDM patients. Diabetes 38:1579-1584
-
(1989)
Diabetes
, vol.38
, pp. 1579-1584
-
-
Trischitta, V.1
Brunetti, A.2
Chiavetta, A.3
Benzi, L.4
Papa, V.5
Vigneri, R.6
-
25
-
-
0028045367
-
Effect of growth hormone on hepatic glucose and insulin metabolism after oral glucose in conscious dogs
-
Okuda Y, Pena J, Chou J, Field JB 1994 Effect of growth hormone on hepatic glucose and insulin metabolism after oral glucose in conscious dogs. Am J Physiol 267:E454-E460
-
(1994)
Am J Physiol
, vol.267
-
-
Okuda, Y.1
Pena, J.2
Chou, J.3
Field, J.B.4
-
26
-
-
13144250135
-
Glucose turnover and insulin clearance after growth hormone treatment in girls with Turner's syndrome
-
Monti LD, Brambilla P, Caumo A, Magni F, Omati S, Nizzoli G, di Natale B, Galli-Kiente M, Cobelli C, Chiumello G, Pozza G 1997 Glucose turnover and insulin clearance after growth hormone treatment in girls with Turner's syndrome. Metabolism 46:1482-1488
-
(1997)
Metabolism
, vol.46
, pp. 1482-1488
-
-
Monti, L.D.1
Brambilla, P.2
Caumo, A.3
Magni, F.4
Omati, S.5
Nizzoli, G.6
Di Natale, B.7
Galli-Kiente, M.8
Cobelli, C.9
Chiumello, G.10
Pozza, G.11
-
27
-
-
0021336220
-
Relationship of body fat topography to insulin sensitivity and metabolic profiles of premenopausal women
-
Evans DJ, Hoffman RG, Kalkhoff RK, Kissebah AH 1984 Relationship of body fat topography to insulin sensitivity and metabolic profiles of premenopausal women. Metabolism 33:68-75
-
(1984)
Metabolism
, vol.33
, pp. 68-75
-
-
Evans, D.J.1
Hoffman, R.G.2
Kalkhoff, R.K.3
Kissebah, A.H.4
-
28
-
-
0023123056
-
Relationship of androgenic activity to splanchnic insulin metabolism and peripheral glucose utilization in premenopausal women
-
Peiris AN, Mueller RA, Strove MF, Smith GA, Kissebah AH 1987 Relationship of androgenic activity to splanchnic insulin metabolism and peripheral glucose utilization in premenopausal women. J Clin Endocrinol Metab 64:162-169
-
(1987)
J Clin Endocrinol Metab
, vol.64
, pp. 162-169
-
-
Peiris, A.N.1
Mueller, R.A.2
Strove, M.F.3
Smith, G.A.4
Kissebah, A.H.5
-
29
-
-
0022846676
-
Splanchnic insulin metabolism in obesity: Influence of body fat distribution
-
Peiris AN, Mueller RA, Strove MF, Smith GA, Kissebah AH 1986 Splanchnic insulin metabolism in obesity: influence of body fat distribution. J Clin Invest 78:1648-1657
-
(1986)
J Clin Invest
, vol.78
, pp. 1648-1657
-
-
Peiris, A.N.1
Mueller, R.A.2
Strove, M.F.3
Smith, G.A.4
Kissebah, A.H.5
-
30
-
-
0027474155
-
Female sex hormones, perinatal, and peripubertal androgenization on hepatocyte insulin dynamics in rats
-
Krakover GR, Meier DA, Kissebah AH 1993 Female sex hormones, perinatal, and peripubertal androgenization on hepatocyte insulin dynamics in rats. Am J Physiol 264:E342-E347
-
(1993)
Am J Physiol
, vol.264
-
-
Krakover, G.R.1
Meier, D.A.2
Kissebah, A.H.3
-
31
-
-
0024447649
-
Abnormal insulin metabolism by specific organs from rats with spontaneous hypertension
-
Mondon CE, Reaven GM, Azhar S, Lee CM, Rabkin R 1989 Abnormal insulin metabolism by specific organs from rats with spontaneous hypertension. Am J Physiol 257:E491-E498
-
(1989)
Am J Physiol
, vol.257
-
-
Mondon, C.E.1
Reaven, G.M.2
Azhar, S.3
Lee, C.M.4
Rabkin, R.5
-
32
-
-
0019182075
-
Functional relationships between insulin binding, action, and degradation. A reassessment
-
Caro JF, Amatruda JM 1980 Functional relationships between insulin binding, action, and degradation. A reassessment. J Biol Chem 255:10052-10055
-
(1980)
J Biol Chem
, vol.255
, pp. 10052-10055
-
-
Caro, J.F.1
Amatruda, J.M.2
-
33
-
-
0019541630
-
Evidence for modulation of insulin action and degradation independently of insulin binding
-
Caro JF, Amatruda JM 1981 Evidence for modulation of insulin action and degradation independently of insulin binding. Am J Physiol 240:E325-E332
-
(1981)
Am J Physiol
, vol.240
-
-
Caro, J.F.1
Amatruda, J.M.2
-
34
-
-
0023627517
-
Different effects of glyburide and glipizide on insulin secretion and hepatic glucose production in normal and NIDDM subjects
-
Groop L, Luzi L, Melander A, Groop PH, Ratheiser K, Simonson DC, DeFronzo RA 1987 Different effects of glyburide and glipizide on insulin secretion and hepatic glucose production in normal and NIDDM subjects. Diabetes 36:1320-1328
-
(1987)
Diabetes
, vol.36
, pp. 1320-1328
-
-
Groop, L.1
Luzi, L.2
Melander, A.3
Groop, P.H.4
Ratheiser, K.5
Simonson, D.C.6
DeFronzo, R.A.7
-
36
-
-
0029919701
-
Glyburide increases the secretion, tissue uptake, and action of insulin in conscious normal dogs
-
Adrogue HJ, Pena J, Comstrock JP 1996 Glyburide increases the secretion, tissue uptake, and action of insulin in conscious normal dogs. Metabolism 45:579-586
-
(1996)
Metabolism
, vol.45
, pp. 579-586
-
-
Adrogue, H.J.1
Pena, J.2
Comstrock, J.P.3
-
37
-
-
0028715939
-
Insulin-degrading activity in experimental liver cirrhosis of the rat
-
Auletta M, Antoniello S, Abrescia N 1994 Insulin-degrading activity in experimental liver cirrhosis of the rat. Enzyme Protein 95:197-201
-
(1994)
Enzyme Protein
, vol.95
, pp. 197-201
-
-
Auletta, M.1
Antoniello, S.2
Abrescia, N.3
-
38
-
-
0027515323
-
Insulin secretion, clearance, and action on glucose metabolism in cirrhotic patients
-
Letiexhe MR, Scheen AJ, Gerard PL, Easterns BH, Pirotte J, Belaiche J, Lefebvre PJ 1993 Insulin secretion, clearance, and action on glucose metabolism in cirrhotic patients. J Clin Endocrinol Metab 77:1263-1268
-
(1993)
J Clin Endocrinol Metab
, vol.77
, pp. 1263-1268
-
-
Letiexhe, M.R.1
Scheen, A.J.2
Gerard, P.L.3
Easterns, B.H.4
Pirotte, J.5
Belaiche, J.6
Lefebvre, P.J.7
-
39
-
-
0024420773
-
Insulin and glucagon degradation in liver are not affected by hepatic cirrhosis
-
Antoniello S, La Rocca S, Cavalcanti E, Auletta M, Salvatore F, Cacciatore L 1989 Insulin and glucagon degradation in liver are not affected by hepatic cirrhosis. Clin Chim Acta 183:343-350
-
(1989)
Clin Chim Acta
, vol.183
, pp. 343-350
-
-
Antoniello, S.1
La Rocca, S.2
Cavalcanti, E.3
Auletta, M.4
Salvatore, F.5
Cacciatore, L.6
-
40
-
-
0026470955
-
Nonreceptor mediated nuclear accumulation of insulin in H35 rat hepatoma cells
-
Harada S, Loten EG, Smith RM, Harett L 1992 Nonreceptor mediated nuclear accumulation of insulin in H35 rat hepatoma cells. J Cell Physiol 153:607-613
-
(1992)
J Cell Physiol
, vol.153
, pp. 607-613
-
-
Harada, S.1
Loten, E.G.2
Smith, R.M.3
Harett, L.4
-
41
-
-
0022389345
-
Acquisition of insulin-dependent protein tyrosine kinase activity during Drosophila embryogenesis
-
Petruzzelli L, Herrera R, Garcia-Arenas R, Rosen OM 1985 Acquisition of insulin-dependent protein tyrosine kinase activity during Drosophila embryogenesis. J Biol Chem 260:16072-16075
-
(1985)
J Biol Chem
, vol.260
, pp. 16072-16075
-
-
Petruzzelli, L.1
Herrera, R.2
Garcia-Arenas, R.3
Rosen, O.M.4
-
44
-
-
0030845447
-
Fate of insulin analogs in intact and nephrectomized rats determined by their receptor binding constants
-
Kruse V, Jensen I, Permin L, Heding A 1497 Fate of insulin analogs in intact and nephrectomized rats determined by their receptor binding constants. Am J Physiol 272:E1089-E1098
-
(1497)
Am J Physiol
, vol.272
-
-
Kruse, V.1
Jensen, I.2
Permin, L.3
Heding, A.4
-
46
-
-
0026728922
-
Time course and kinetics of proximal tubular processing of insulin
-
Nielsen S 1992 Time course and kinetics of proximal tubular processing of insulin. Am J Physiol 262:F813-F822
-
(1992)
Am J Physiol
, vol.262
-
-
Nielsen, S.1
-
47
-
-
0027524874
-
Degradation of insulin by isolated rat renal cortical endosomes
-
Fawcett J, Rabkin R 1993 Degradation of insulin by isolated rat renal cortical endosomes. Endocrinology 133:1539-1547
-
(1993)
Endocrinology
, vol.133
, pp. 1539-1547
-
-
Fawcett, J.1
Rabkin, R.2
-
49
-
-
0028797109
-
Sequential processing of insulin by cultured kidney cells
-
Fawcett J, Rabkin R 1995 Sequential processing of insulin by cultured kidney cells. Endocrinology 136:39-45
-
(1995)
Endocrinology
, vol.136
, pp. 39-45
-
-
Fawcett, J.1
Rabkin, R.2
-
51
-
-
0024465414
-
Retroendocytosis of insulin in a cultured kidney epithelial cell line
-
Dahl DC, Tsao T, Duckworth WC, Mahoney MJ, Rabkin R 1989 Retroendocytosis of insulin in a cultured kidney epithelial cell line. Am J Physiol 257:C190-C196
-
(1989)
Am J Physiol
, vol.257
-
-
Dahl, D.C.1
Tsao, T.2
Duckworth, W.C.3
Mahoney, M.J.4
Rabkin, R.5
-
52
-
-
0025169553
-
Effect of bacitracin on the retroendocytosis and degradation of insulin in cultured kidney epithelial cell line
-
Dahl DC, Tsao T, Duckworth WC, Frank BH, Rabkin R 1990 Effect of bacitracin on the retroendocytosis and degradation of insulin in cultured kidney epithelial cell line. Diabetes 39:1339-1346
-
(1990)
Diabetes
, vol.39
, pp. 1339-1346
-
-
Dahl, D.C.1
Tsao, T.2
Duckworth, W.C.3
Frank, B.H.4
Rabkin, R.5
-
53
-
-
0025285573
-
Effect of the insulin degradation inhibitors bacitracin and chloroquine on insulin binding data to H35 rat hepatoma cells
-
de Vries CP, Van Haeften TW, Rao BR, Van Der Veen EA 1990 Effect of the insulin degradation inhibitors bacitracin and chloroquine on insulin binding data to H35 rat hepatoma cells. Diabete Metab 16:70-76
-
(1990)
Diabete Metab
, vol.16
, pp. 70-76
-
-
De Vries, C.P.1
Van Haeften, T.W.2
Rao, B.R.3
Van Der Veen, E.A.4
-
54
-
-
0027256091
-
Purification of nonantibiotic insulinase inhibitors from bacitracin
-
Medina V, Kesner L, Stracher A 1993 Purification of nonantibiotic insulinase inhibitors from bacitracin. Biochem Med Metab Biol 49:255-264
-
(1993)
Biochem Med Metab Biol
, vol.49
, pp. 255-264
-
-
Medina, V.1
Kesner, L.2
Stracher, A.3
-
56
-
-
0018597613
-
Effect of prolonged uremia on insulin metabolism by isolated liver and muscle
-
Rabkin R, Unterhalter SA, Duckworth WC 1979 Effect of prolonged uremia on insulin metabolism by isolated liver and muscle. Kidney Int 16:433-439
-
(1979)
Kidney Int
, vol.16
, pp. 433-439
-
-
Rabkin, R.1
Unterhalter, S.A.2
Duckworth, W.C.3
-
57
-
-
0018635256
-
Insulin binding and degradation by muscles from streptozotocin-diabetic rats
-
Duckworth WC, Gifford D, Kirabchi AE, Runyan K, Solomon SS 1979 Insulin binding and degradation by muscles from streptozotocin-diabetic rats. Diabetes 28:414-417
-
(1979)
Diabetes
, vol.28
, pp. 414-417
-
-
Duckworth, W.C.1
Gifford, D.2
Kirabchi, A.E.3
Runyan, K.4
Solomon, S.S.5
-
58
-
-
0023107822
-
Effects of metalloendoprotease inhibitors on insulin binding, internalization and processing in adipocytes
-
Jochen A, Berhanu P 1987 Effects of metalloendoprotease inhibitors on insulin binding, internalization and processing in adipocytes. Biochem Biophys Res Commun 142:205-212
-
(1987)
Biochem Biophys Res Commun
, vol.142
, pp. 205-212
-
-
Jochen, A.1
Berhanu, P.2
-
59
-
-
0029764427
-
Adipose tissue extraction of circulating insulin in anaesthetized Zucker obese rats
-
Ardevol A, Adan C, Canas X, Rafecas I, Mesteve M, Remesar X, Fernandez-Lopez JA, Alemany M 1996 Adipose tissue extraction of circulating insulin in anaesthetized Zucker obese rats. Int J Obes 20:837-841
-
(1996)
Int J Obes
, vol.20
, pp. 837-841
-
-
Ardevol, A.1
Adan, C.2
Canas, X.3
Rafecas, I.4
Mesteve, M.5
Remesar, X.6
Fernandez-Lopez, J.A.7
Alemany, M.8
-
60
-
-
0019614836
-
Insulin binding, internalization, and receptor regulation in cultured human fibroblasts
-
Baldwin Jr D, Prince M, Tsai P, Johnson C, Lotan R, Rubenstein AH, Olefsky JM 1981 Insulin binding, internalization, and receptor regulation in cultured human fibroblasts. Am J Physiol 241:E251-E260
-
(1981)
Am J Physiol
, vol.241
-
-
Baldwin Jr., D.1
Prince, M.2
Tsai, P.3
Johnson, C.4
Lotan, R.5
Rubenstein, A.H.6
Olefsky, J.M.7
-
61
-
-
0021924133
-
Characterization of insulin-degrading activity of intact and subcellular components of human fibroblasts
-
Stentz FB, Harris HL, Kitabchi AE 1985 Characterization of insulin-degrading activity of intact and subcellular components of human fibroblasts. Endocrinology 116:926-934
-
(1985)
Endocrinology
, vol.116
, pp. 926-934
-
-
Stentz, F.B.1
Harris, H.L.2
Kitabchi, A.E.3
-
63
-
-
0022625436
-
Phytohemagglutinin (PHA) activated human T lymphocytes: Concomitant appearance of insulin binding, degradation, and insulin mediated activation of pyruvate dehydrogenase
-
Buffington CK, el-Shiekh T, Kitabchi AE, Matteri R 1986 Phytohemagglutinin (PHA) activated human T lymphocytes: concomitant appearance of insulin binding, degradation, and insulin mediated activation of pyruvate dehydrogenase. Biochem Biophys Res Commun 134:412-419
-
(1986)
Biochem Biophys Res Commun
, vol.134
, pp. 412-419
-
-
Buffington, C.K.1
El-Shiekh, T.2
Kitabchi, A.E.3
Matteri, R.4
-
64
-
-
0028948310
-
Insulin-degrading enzyme in a human colon adenocarcinoma cell line (Caco-2)
-
Bai JP, Hsu MJ, Shier WT 1995 Insulin-degrading enzyme in a human colon adenocarcinoma cell line (Caco-2). Pharm Res 12: 513-516
-
(1995)
Pharm Res
, vol.12
, pp. 513-516
-
-
Bai, J.P.1
Hsu, M.J.2
Shier, W.T.3
-
65
-
-
0018877517
-
The time course of insulin degradation in the perifused isolated fat cell
-
Huber CT, Solomon SS, Duckworth WC 1980 The time course of insulin degradation in the perifused isolated fat cell. J Clin Invest 65:461-468
-
(1980)
J Clin Invest
, vol.65
, pp. 461-468
-
-
Huber, C.T.1
Solomon, S.S.2
Duckworth, W.C.3
-
66
-
-
0030689708
-
Insulin is degraded extracellularly in wounds by insulin-degrading enzyme (EC 3.4.24.56)
-
Shearer JD, Coulter CF, Engeland WC, Roth RA, Caldwell MD 1997 Insulin is degraded extracellularly in wounds by insulin-degrading enzyme (EC 3.4.24.56). Am J Physiol 273:E657-E664
-
(1997)
Am J Physiol
, vol.273
-
-
Shearer, J.D.1
Coulter, C.F.2
Engeland, W.C.3
Roth, R.A.4
Caldwell, M.D.5
-
67
-
-
0023200307
-
High performance liquid chromatographic analysis of insulin degradation products from isolated hepatocytes: Effects of inhibitors suggest intracellular and extracellular pathways
-
Hamel FG, Peavy DE, Ryan MP, Duckworth WC 1987 High performance liquid chromatographic analysis of insulin degradation products from isolated hepatocytes: effects of inhibitors suggest intracellular and extracellular pathways. Diabetes 36:702-708
-
(1987)
Diabetes
, vol.36
, pp. 702-708
-
-
Hamel, F.G.1
Peavy, D.E.2
Ryan, M.P.3
Duckworth, W.C.4
-
68
-
-
0023555128
-
Insulin-stimulated glucose transport and insulin internalization share a common postbinding step in adipocytes
-
Jochen AL, Berhanu P 1987 Insulin-stimulated glucose transport and insulin internalization share a common postbinding step in adipocytes. Diabetes 36:542-545
-
(1987)
Diabetes
, vol.36
, pp. 542-545
-
-
Jochen, A.L.1
Berhanu, P.2
-
69
-
-
0025218961
-
2-macroglobulin and insulin correlate with separate routes of ligand-receptor complex internalization
-
2-macroglobulin and insulin correlate with separate routes of ligand-receptor complex internalization. Endocrinology 126:1551-1560
-
(1990)
Endocrinology
, vol.126
, pp. 1551-1560
-
-
Smith, R.M.1
Jarett, L.2
-
70
-
-
0025105992
-
The dissociation and degradation of internalized insulin occur in the endosomes of rat hepatoma cells
-
Backer JM, Kahn CR, White MF 1990 The dissociation and degradation of internalized insulin occur in the endosomes of rat hepatoma cells. J Biol Chem 265:14828-14835
-
(1990)
J Biol Chem
, vol.265
, pp. 14828-14835
-
-
Backer, J.M.1
Kahn, C.R.2
White, M.F.3
-
71
-
-
0027157869
-
Inhibition of insulin-degrading enzyme increases translocation of insulin to the nucleus in H35 rat hepatoma cells: Evidence of a cytosolic pathway
-
Harada S, Smith RM, Smith JA, Jarett L 1993 Inhibition of insulin-degrading enzyme increases translocation of insulin to the nucleus in H35 rat hepatoma cells: evidence of a cytosolic pathway. Endocrinology 132:2293-2298
-
(1993)
Endocrinology
, vol.132
, pp. 2293-2298
-
-
Harada, S.1
Smith, R.M.2
Smith, J.A.3
Jarett, L.4
-
72
-
-
0001029405
-
Immunological demonstration of the accumulation of insulin, but not insulin receptors, in nuclei of insulin-treated cells
-
Soler AP, Thompson KA, Smith RM, Jarett L 1989 Immunological demonstration of the accumulation of insulin, but not insulin receptors, in nuclei of insulin-treated cells. Proc Natl Acad Sci USA 86:6640-6644
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6640-6644
-
-
Soler, A.P.1
Thompson, K.A.2
Smith, R.M.3
Jarett, L.4
-
73
-
-
0023145167
-
Ultrastructural evidence for the accumulation of insulin in nuclei of intact 3T3-L1 adipocytes by an insulin-receptor mediated process
-
Smith RM, Jarett L 1987 Ultrastructural evidence for the accumulation of insulin in nuclei of intact 3T3-L1 adipocytes by an insulin-receptor mediated process. Proc Natl Acad Sci USA 84:459-463
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 459-463
-
-
Smith, R.M.1
Jarett, L.2
-
74
-
-
0024846376
-
Intranuclear localization of insulin in rat hepatoma cells: Insulin/matrix association
-
Thompson KA, Soler AP, Smith RM, Jarett L 1989 Intranuclear localization of insulin in rat hepatoma cells: insulin/matrix association. Eur J Cell Biol 50:442-446
-
(1989)
Eur J Cell Biol
, vol.50
, pp. 442-446
-
-
Thompson, K.A.1
Soler, A.P.2
Smith, R.M.3
Jarett, L.4
-
75
-
-
0025282386
-
Partial characterization of mechanism of insulin accumulation in H35 hepatoma cell nuclei
-
Smith RM, Jarett L 1990 Partial characterization of mechanism of insulin accumulation in H35 hepatoma cell nuclei. Diabetes 39: 683-689
-
(1990)
Diabetes
, vol.39
, pp. 683-689
-
-
Smith, R.M.1
Jarett, L.2
-
76
-
-
0028817556
-
Demonstration of specific insulin binding to cytosolic proteins in H35 hepatoma cells, rat liver and skeletal muscle
-
Harada S, Smith RM, Smith JA, Shah N, Jarett L 1995 Demonstration of specific insulin binding to cytosolic proteins in H35 hepatoma cells, rat liver and skeletal muscle. Biochem J 306:21-28
-
(1995)
Biochem J
, vol.306
, pp. 21-28
-
-
Harada, S.1
Smith, R.M.2
Smith, J.A.3
Shah, N.4
Jarett, L.5
-
77
-
-
0019824772
-
125I iodoinsulin entry into adult rat hepatocytes in vivo: Evidence for multiple sites of hormone localization
-
125I iodoinsulin entry into adult rat hepatocytes in vivo: evidence for multiple sites of hormone localization. Endocrinology 108:1821-1828
-
(1981)
Endocrinology
, vol.108
, pp. 1821-1828
-
-
Goldfine, I.D.1
Jones, A.L.2
Hradek, G.T.3
Wong, K.Y.4
-
78
-
-
7844226081
-
Biology of disease. Receptor-mediated endocytosis and intracellular processing of insulin: Ultrastructural and biochemical evidence for cell-specific heterogeneity and distinction from nonhormonal ligands
-
Rubin E, Damjanov I (eds) Humana Press Inc., Clifton, NJ
-
Smith RM, Jarett L 1989 Biology of disease. Receptor-mediated endocytosis and intracellular processing of insulin: ultrastructural and biochemical evidence for cell-specific heterogeneity and distinction from nonhormonal ligands. In: Rubin E, Damjanov I (eds) Pathology Reviews. Humana Press Inc., Clifton, NJ, pp 37-53
-
(1989)
Pathology Reviews
, pp. 37-53
-
-
Smith, R.M.1
Jarett, L.2
-
79
-
-
0023121306
-
The effect of insulin concentration on retroendocytosis in isolated rat adipocytes
-
Levy J, Olefsky JM 1987 The effect of insulin concentration on retroendocytosis in isolated rat adipocytes. Endocrinology 120: 450-456
-
(1987)
Endocrinology
, vol.120
, pp. 450-456
-
-
Levy, J.1
Olefsky, J.M.2
-
80
-
-
17044443892
-
Insulin-degrading enzyme is capable of degrading receptor-bound Insulin
-
Yonezawa K, Yokono K, Shii K, Hari J, Yaso S, Amano K, Sakamoto T, Kawase Y, Akiyama H, Nagata M, Baba S 1988 Insulin-degrading enzyme is capable of degrading receptor-bound Insulin. Biochem Biophys Res Commun 150:605-614
-
(1988)
Biochem Biophys Res Commun
, vol.150
, pp. 605-614
-
-
Yonezawa, K.1
Yokono, K.2
Shii, K.3
Hari, J.4
Yaso, S.5
Amano, K.6
Sakamoto, T.7
Kawase, Y.8
Akiyama, H.9
Nagata, M.10
Baba, S.11
-
81
-
-
0031550507
-
Overexpression of insulin degrading enzyme: Cellular localization and effects on insulin signaling
-
Seta KA, Roth RA 1997 Overexpression of insulin degrading enzyme: cellular localization and effects on insulin signaling. Biochem Biophys Res Commun 231:167-171
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 167-171
-
-
Seta, K.A.1
Roth, R.A.2
-
82
-
-
0022466812
-
Localization of insulin degradation products to an intracellular site in isolated rat hepatocytes
-
Pell ME, Duckworth WC, Peavy DE 1986 Localization of insulin degradation products to an intracellular site in isolated rat hepatocytes. Biochem Biophys Res Commun 137:1034-1040
-
(1986)
Biochem Biophys Res Commun
, vol.137
, pp. 1034-1040
-
-
Pell, M.E.1
Duckworth, W.C.2
De Peavy3
-
83
-
-
0025076312
-
Characterization of insulin degradation products generated in liver endosomes: In vivo and in vitro studies
-
Clot JP, Janicot M, Fouque F, Desbuquois B, Haumont PY, Lederer F 1990 Characterization of insulin degradation products generated in liver endosomes: in vivo and in vitro studies. Mol Cell Endocrinol 72:175-185
-
(1990)
Mol Cell Endocrinol
, vol.72
, pp. 175-185
-
-
Clot, J.P.1
Janicot, M.2
Fouque, F.3
Desbuquois, B.4
Haumont, P.Y.5
Lederer, F.6
-
84
-
-
0023876630
-
Internalized insulin-receptor complexes are unidirectionally translocated to chloroquine-sensitive degradative sites
-
Berhanu P 1988 Internalized insulin-receptor complexes are unidirectionally translocated to chloroquine-sensitive degradative sites. J Biol Chem 263:5961-5969
-
(1988)
J Biol Chem
, vol.263
, pp. 5961-5969
-
-
Berhanu, P.1
-
85
-
-
0024997853
-
Receptor-mediated internalization of insulin requires a 12-amino acid sequence in the juxtamembrane region of the insulin receptor beta-subunit
-
Backer JM, Kahn CR, Cahill DA, Ullrich A, White MF 1990 Receptor-mediated internalization of insulin requires a 12-amino acid sequence in the juxtamembrane region of the insulin receptor beta-subunit. J Biol Chem 265:16450-16454
-
(1990)
J Biol Chem
, vol.265
, pp. 16450-16454
-
-
Backer, J.M.1
Kahn, C.R.2
Cahill, D.A.3
Ullrich, A.4
White, M.F.5
-
86
-
-
0023226340
-
Defective internalization of insulin and its receptor in cells expressing mutated insulin receptors lacking kinase activity
-
Hari J, Roth RA 1987 Defective internalization of insulin and its receptor in cells expressing mutated insulin receptors lacking kinase activity. J Biol Chem 262:15341-15344
-
(1987)
J Biol Chem
, vol.262
, pp. 15341-15344
-
-
Hari, J.1
Roth, R.A.2
-
87
-
-
0027260562
-
Two steps of insulin receptor internalization depend on different domains of the beta-subunit
-
Carpentier JL, Paccaud PP, Backer JM, Gilbert A, Orci L, Kahn CR 1993 Two steps of insulin receptor internalization depend on different domains of the beta-subunit. J Cell Biol 122:1243-1252
-
(1993)
J Cell Biol
, vol.122
, pp. 1243-1252
-
-
Carpentier, J.L.1
Paccaud, P.P.2
Backer, J.M.3
Gilbert, A.4
Orci, L.5
Kahn, C.R.6
-
88
-
-
0030667408
-
Differential effect of pp120 on insulin endocytosis by two variant insulin receptor isoforms
-
Calzi SL, Choice CV, Najjar SM 1997 Differential effect of pp120 on insulin endocytosis by two variant insulin receptor isoforms. Am J Physiol 273:E801-E808
-
(1997)
Am J Physiol
, vol.273
-
-
Calzi, S.L.1
Choice, C.V.2
Najjar, S.M.3
-
89
-
-
0025867117
-
Different ligand affinities of the two human insulin receptor splice variants are reflected in parallel changes in sensitivity for insulin action
-
McClain DA 1991 Different ligand affinities of the two human insulin receptor splice variants are reflected in parallel changes in sensitivity for insulin action. Mol Endocrinol 5:734-739
-
(1991)
Mol Endocrinol
, vol.5
, pp. 734-739
-
-
McClain, D.A.1
-
90
-
-
0025941580
-
Functional properties of two naturally occurring isoforms of the human insulin receptor in Chinese hamster ovary cells
-
Yamaguchi Y, Flier JS, Yokota A, Benecke H, Backer JM, Moller DE 1991 Functional properties of two naturally occurring isoforms of the human insulin receptor in Chinese hamster ovary cells. Endocrinology 129:2058-2066
-
(1991)
Endocrinology
, vol.129
, pp. 2058-2066
-
-
Yamaguchi, Y.1
Flier, J.S.2
Yokota, A.3
Benecke, H.4
Backer, J.M.5
De Moller6
-
91
-
-
0025730515
-
Degradation of intraendosomal insulin by insulin degrading enzyme without acidification
-
Hamel FG, Mahoney MJ, Duckworth WC 1991 Degradation of intraendosomal insulin by insulin degrading enzyme without acidification. Diabetes 40:436-443
-
(1991)
Diabetes
, vol.40
, pp. 436-443
-
-
Hamel, F.G.1
Mahoney, M.J.2
Duckworth, W.C.3
-
92
-
-
0023924128
-
Isolation of insulin degradation products from endosomes derived from intact rat liver
-
Hamel FG, Posner BI, Bergeron JJM, Frank BH, Duckworth WC 1988 Isolation of insulin degradation products from endosomes derived from intact rat liver. J Biol Chem 263:6703-6708
-
(1988)
J Biol Chem
, vol.263
, pp. 6703-6708
-
-
Hamel, F.G.1
Posner, B.I.2
Bergeron, J.J.M.3
Frank, B.H.4
Duckworth, W.C.5
-
93
-
-
0024985647
-
Cellular and endosomal degradation
-
Nishizuka Y, Endok M, Tanaka C (eds) Raven Press, New York
-
Duckworth WC, Hamel FG 1990 Cellular and endosomal degradation. In: Nishizuka Y, Endok M, Tanaka C (eds) The Biology and Medicine of Signal Transduction. Raven Press, New York, pp 521-528
-
(1990)
The Biology and Medicine of Signal Transduction
, pp. 521-528
-
-
Duckworth, W.C.1
Hamel, F.G.2
-
94
-
-
0025397066
-
125I]-insulin metabolism by the rat liver in vivo: Evidence that a neutral thiol-protease mediates rapid intracellular insulin degradation
-
125I]-insulin metabolism by the rat liver in vivo: evidence that a neutral thiol-protease mediates rapid intracellular insulin degradation. Metabolism 39: 231-241
-
(1990)
Metabolism
, vol.39
, pp. 231-241
-
-
Williams, F.G.1
Johnson, D.E.2
Bauer, G.E.3
-
95
-
-
0028040778
-
Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme
-
Authier F, Rachubinski RA, Posner BI, Bergeron JJM 1994 Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme. J Biol Chem 269:3010-3016
-
(1994)
J Biol Chem
, vol.269
, pp. 3010-3016
-
-
Authier, F.1
Rachubinski, R.A.2
Posner, B.I.3
Bergeron, J.J.M.4
-
96
-
-
0030456535
-
The characterization of endosomal insulin degradation intermediates and their sequence of production
-
Seabright PJ, Smith GD 1996 The characterization of endosomal insulin degradation intermediates and their sequence of production. Biochem J 320:947-956
-
(1996)
Biochem J
, vol.320
, pp. 947-956
-
-
Seabright, P.J.1
Smith, G.D.2
-
97
-
-
0029811040
-
Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells
-
Authier F, Cameron PH, Taupin V 1996 Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells. Biochem J 319:149-158
-
(1996)
Biochem J
, vol.319
, pp. 149-158
-
-
Authier, F.1
Cameron, P.H.2
Taupin, V.3
-
98
-
-
0023164755
-
125I insulin with a cytosolic insulin-degrading enzyme: Detection by covalent cross-linking and immuno-precipitation with a monoclonal antibody
-
125I insulin with a cytosolic insulin-degrading enzyme: detection by covalent cross-linking and immuno-precipitation with a monoclonal antibody. Endocrinology 120:829-831
-
(1987)
Endocrinology
, vol.120
, pp. 829-831
-
-
Hari, J.1
Shii, K.2
Roth, R.A.3
-
99
-
-
0024990132
-
Natural regulatory mechanisms of insulin degradation by insulin degrading enzyme
-
Akiyama H, Yokono K, Shii K, Ogawa W, Taniguchi H, Baba S, Kasuga M 1990 Natural regulatory mechanisms of insulin degradation by insulin degrading enzyme. Biochem Biophys Res Commun 170:1325-1330
-
(1990)
Biochem Biophys Res Commun
, vol.170
, pp. 1325-1330
-
-
Akiyama, H.1
Yokono, K.2
Shii, K.3
Ogawa, W.4
Taniguchi, H.5
Baba, S.6
Kasuga, M.7
-
100
-
-
0028167733
-
1,10-Phenanthroline increases nuclear accumulation of insulin in response to inhibiting insulin degradation but has a biphasic effect on insulin's ability to increase mRNa levels
-
Harada S, Smith RM, Jarett L 1994 1,10-Phenanthroline increases nuclear accumulation of insulin in response to inhibiting insulin degradation but has a biphasic effect on insulin's ability to increase mRNA levels. DNA Cell Biol 13:487-493
-
(1994)
DNA Cell Biol
, vol.13
, pp. 487-493
-
-
Harada, S.1
Smith, R.M.2
Jarett, L.3
-
101
-
-
0023001170
-
Identification of some cleavage sites of insulin by insulin proteinase
-
Davies JG, Muir AV, Offord RE 1986 Identification of some cleavage sites of insulin by insulin proteinase. Biochem J 240:609-612
-
(1986)
Biochem J
, vol.240
, pp. 609-612
-
-
Davies, J.G.1
Muir, A.V.2
Offord, R.E.3
-
103
-
-
0024592433
-
Drosophila insulin degrading enzyme and rat skeletal muscle insulin protease cleave insulin at similar sites
-
Duckworth WC, Garcia JV, Liepnieks JJ, Hamel FG, Hermodson MA, Rosner MR 1989 Drosophila insulin degrading enzyme and rat skeletal muscle insulin protease cleave insulin at similar sites. Biochemistry 28:2471-2477
-
(1989)
Biochemistry
, vol.28
, pp. 2471-2477
-
-
Duckworth, W.C.1
Garcia, J.V.2
Liepnieks, J.J.3
Hamel, F.G.4
Hermodson, M.A.5
Rosner, M.R.6
-
104
-
-
0024212845
-
High performance liquid chromatographic analysis of insulin degradation products from a cultured kidney cell line
-
Duckworth W, Hamel F, Liepnieks J, Frank B, Yagil C, Rabkin R 1988 High performance liquid chromatographic analysis of insulin degradation products from a cultured kidney cell line. Endocrinology 123:2701-2708
-
(1988)
Endocrinology
, vol.123
, pp. 2701-2708
-
-
Duckworth, W.1
Hamel, F.2
Liepnieks, J.3
Frank, B.4
Yagil, C.5
Rabkin, R.6
-
105
-
-
0023493316
-
Identification of a chain cleavage sites in intact insulin produced by insulin protease and isolated hepatocytes
-
Duckworth WC, Hamel FG, Liepnieks JJ, Peavy DE, Ryan MP, Hermodson MA, Frank BH 1987 Identification of A chain cleavage sites in intact insulin produced by insulin protease and isolated hepatocytes. Biochem Biophys Res Commun 147:615-621
-
(1987)
Biochem Biophys Res Commun
, vol.147
, pp. 615-621
-
-
Duckworth, W.C.1
Hamel, F.G.2
Liepnieks, J.J.3
Peavy, D.E.4
Ryan, M.P.5
Hermodson, M.A.6
Frank, B.H.7
-
106
-
-
0040851276
-
High performance liquid chromatographic analysis of insulin degradation products from perfused rat kidney
-
Duckworth WC, Hamel FG, Liepnieks JJ, Peavy DE, Frank BH, Rabkin R 1989 High performance liquid chromatographic analysis of insulin degradation products from perfused rat kidney. Am J Physiol 256:E208-E214
-
(1989)
Am J Physiol
, vol.256
-
-
Duckworth, W.C.1
Hamel, F.G.2
Liepnieks, J.J.3
Peavy, D.E.4
Frank, B.H.5
Rabkin, R.6
-
107
-
-
0023906369
-
Degradation products of insulin generated by hepatocytes and by insulin protease
-
Duckworth WC, Hamel FG, Peavy DE, Liepnieks JJ, Ryan MP, Hermodson MA, Frank BH 1988 Degradation products of insulin generated by hepatocytes and by insulin protease. J Biol Chem 263:1826-1833
-
(1988)
J Biol Chem
, vol.263
, pp. 1826-1833
-
-
Duckworth, W.C.1
Hamel, F.G.2
Peavy, D.E.3
Liepnieks, J.J.4
Ryan, M.P.5
Hermodson, M.A.6
Frank, B.H.7
-
109
-
-
0022647783
-
High performance liquid chromatographic analysis of insulin degradation by rat skeletal muscle insulin protease
-
Hamel FG, Peavy DE, Ryan MP, Duckworth WC 1986 High performance liquid chromatographic analysis of insulin degradation by rat skeletal muscle insulin protease. Endocrinology 118:328-333
-
(1986)
Endocrinology
, vol.118
, pp. 328-333
-
-
Hamel, F.G.1
Peavy, D.E.2
Ryan, M.P.3
Duckworth, W.C.4
-
111
-
-
0023709846
-
Identification by fast atom bombardment mass spectrometry of insulin fragments produced by insulin proteinase
-
Savoy LA, Jones RM, Pochon S, Davies JG, Muir AV, Offord RE, Rose K 1988 Identification by fast atom bombardment mass spectrometry of insulin fragments produced by insulin proteinase. Biochem J 249:215-222
-
(1988)
Biochem J
, vol.249
, pp. 215-222
-
-
Savoy, L.A.1
Jones, R.M.2
Pochon, S.3
Davies, J.G.4
Muir, A.V.5
Offord, R.E.6
Rose, K.7
-
112
-
-
0024357958
-
Identification of insulin intermediates and sites of cleavage of native insulin by insulin protease from human fibroblasts
-
Stentz FB, Kitabchi A, Schilling JW, Schronk LR, Seyer JM 1989 Identification of insulin intermediates and sites of cleavage of native insulin by insulin protease from human fibroblasts. J Biol Chem 264:20275-20282
-
(1989)
J Biol Chem
, vol.264
, pp. 20275-20282
-
-
Stentz, F.B.1
Kitabchi, A.2
Schilling, J.W.3
Schronk, L.R.4
Seyer, J.M.5
-
113
-
-
0026471959
-
Rat insulin-degrading enzyme: Cleavage pattern of the natriuretic peptide hormones ANP, BNP and CNP revealed by HPLC and mass spectrometry
-
Muller D, Schulze C, Baumeister H, Buck F, Richter D 1992 Rat insulin-degrading enzyme: cleavage pattern of the natriuretic peptide hormones ANP, BNP and CNP revealed by HPLC and mass spectrometry. Biochemistry 31:11138-11143
-
(1992)
Biochemistry
, vol.31
, pp. 11138-11143
-
-
Muller, D.1
Schulze, C.2
Baumeister, H.3
Buck, F.4
Richter, D.5
-
114
-
-
0042196741
-
Insulin degradation: Assays and enzymes
-
Kahn C, Harrison L (eds) Alan R. Liss, Inc., New York
-
Ryan MP, Duckworth WC 1988 Insulin degradation: assays and enzymes. In: Kahn C, Harrison L (eds) The Insulin Receptor. Alan R. Liss, Inc., New York, vol 1:29-57
-
(1988)
The Insulin Receptor
, vol.1
, pp. 29-57
-
-
Ryan, M.P.1
Duckworth, W.C.2
-
115
-
-
0020527196
-
Receptor binding properties of monoiodotyrosyl insulin isomers purified by high performance liquid chromatography
-
Frank BH, Peavy DE, Hooker CS, Duckworth WC 1983 Receptor binding properties of monoiodotyrosyl insulin isomers purified by high performance liquid chromatography. Diabetes 32:705-711
-
(1983)
Diabetes
, vol.32
, pp. 705-711
-
-
Frank, B.H.1
Peavy, D.E.2
Hooker, C.S.3
Duckworth, W.C.4
-
116
-
-
0021151581
-
The degradation of monoiodotyrosyl insulin isomers by insulin protease
-
Ryan MP, Peavy DE, Frank BH, Duckworth WC 1984 The degradation of monoiodotyrosyl insulin isomers by insulin protease. Endocrinology 115:591-599
-
(1984)
Endocrinology
, vol.115
, pp. 591-599
-
-
Ryan, M.P.1
Peavy, D.E.2
Frank, B.H.3
Duckworth, W.C.4
-
117
-
-
70350223357
-
The inactivation of insulin bytissue extracts. I. The distribution and properties of insulin inactivating extracts (insulinase)
-
Mirsky IA, Broh-Kahn RH 1949 The inactivation of insulin bytissue extracts. I. The distribution and properties of insulin inactivating extracts (insulinase). Arch Biochem 20:1-9
-
(1949)
Arch Biochem
, vol.20
, pp. 1-9
-
-
Mirsky, I.A.1
Broh-Kahn, R.H.2
-
120
-
-
0022445076
-
Inhibition of insulin degradation by hepatoma cells after microinjections of monoclonal antibodies to a specific cytosolic protease
-
Shii K, Roth RA 1986 Inhibition of insulin degradation by hepatoma cells after microinjections of monoclonal antibodies to a specific cytosolic protease. Proc Nat Acad Sci USA 83:4147-4151
-
(1986)
Proc Nat Acad Sci USA
, vol.83
, pp. 4147-4151
-
-
Shii, K.1
Roth, R.A.2
-
121
-
-
0026049145
-
Regulation of insulin degradation: Expression of an evolutionary conserved insulin-degrading enzyme increases degradation via an intracellular pathway
-
Kuo WL, Gehm BD, Rosner MR 1991 Regulation of insulin degradation: expression of an evolutionary conserved insulin-degrading enzyme increases degradation via an intracellular pathway. Mol Endocrinol 5:1467-1476
-
(1991)
Mol Endocrinol
, vol.5
, pp. 1467-1476
-
-
Kuo, W.L.1
Gehm, B.D.2
Rosner, M.R.3
-
122
-
-
0028504315
-
Editorial: Increasing understanding of calmodulin-insulin interactions
-
Duckworth WC 1994 Editorial: Increasing understanding of calmodulin-insulin interactions. J Lab Clin Med 124:311-312
-
(1994)
J Lab Clin Med
, vol.124
, pp. 311-312
-
-
Duckworth, W.C.1
-
123
-
-
0024215473
-
Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III
-
Affholter JA, Fried VA, Roth RA 1988 Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III. Science 242:1415-1418
-
(1988)
Science
, vol.242
, pp. 1415-1418
-
-
Affholter, J.A.1
Fried, V.A.2
Roth, R.A.3
-
124
-
-
0029022718
-
Insulysin and pitrilysin: Insulin-degrading enzymes of mammals and bacteria
-
Becker AB, Roth RA 1995 Insulysin and pitrilysin: insulin-degrading enzymes of mammals and bacteria. Methods Enzymol 248: 693-703
-
(1995)
Methods Enzymol
, vol.248
, pp. 693-703
-
-
Becker, A.B.1
Roth, R.A.2
-
125
-
-
0025266363
-
Human red blood cell insulin-degrading enzyme and rat skeletal muscle insulin protease share antigenic sites and generate identical products from insulin
-
Duckworth WC, Hamel FG, Bennett RG, Ryan MP, Roth RA 1990 Human red blood cell insulin-degrading enzyme and rat skeletal muscle insulin protease share antigenic sites and generate identical products from insulin. J Biol Chem 265:2984-2987
-
(1990)
J Biol Chem
, vol.265
, pp. 2984-2987
-
-
Duckworth, W.C.1
Hamel, F.G.2
Bennett, R.G.3
Ryan, M.P.4
Roth, R.A.5
-
127
-
-
0021262237
-
The insulin and glucagon degrading proteinase of rat liver: A metal dependent enzyme
-
Ansorge S, Bohley PL, Kirschke J, Langner J, Wiederanders B 1984 The insulin and glucagon degrading proteinase of rat liver: a metal dependent enzyme. Biomed Biochim Acta 43:39-46
-
(1984)
Biomed Biochim Acta
, vol.43
, pp. 39-46
-
-
Ansorge, S.1
Bohley, P.L.2
Kirschke, J.3
Langner, J.4
Wiederanders, B.5
-
128
-
-
0027454093
-
Functional analysis of conserved residues in the active site of insulin-degrading enzyme
-
Perlman RK, Gehm BD, Kuo WL, Rosner MR 1993 Functional analysis of conserved residues in the active site of insulin-degrading enzyme. J Biol Chem 268:21538-21544
-
(1993)
J Biol Chem
, vol.268
, pp. 21538-21544
-
-
Perlman, R.K.1
Gehm, B.D.2
Kuo, W.L.3
Rosner, M.R.4
-
129
-
-
0026516458
-
An unusual active site identified in a family of zinc metalloendopeptidases
-
Becker AB, Roth RA 1992 An unusual active site identified in a family of zinc metalloendopeptidases. Proc Natl Acad Sci USA 89:3835-3839
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3835-3839
-
-
Becker, A.B.1
Roth, R.A.2
-
130
-
-
0027263747
-
Identification of glutamate-169 as the third zinc-binding residue in proteinase III, a member of the family of insulin-degrading enzymes
-
Becker AB, Roth RA 1993 Identification of glutamate-169 as the third zinc-binding residue in proteinase III, a member of the family of insulin-degrading enzymes. Biochem J 292:137-142
-
(1993)
Biochem J
, vol.292
, pp. 137-142
-
-
Becker, A.B.1
Roth, R.A.2
-
131
-
-
0027471458
-
Mutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding
-
Gehm BD, Kuo WL, Periman RK, Rosner MR 1993 Mutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding. J Biol Chem 268: 7943-7948
-
(1993)
J Biol Chem
, vol.268
, pp. 7943-7948
-
-
Gehm, B.D.1
Kuo, W.L.2
Periman, R.K.3
Rosner, M.R.4
-
132
-
-
0020619418
-
Partial characterization of an endogenous inhibitor of a calcium-dependent form of insulin protease
-
Ryan MP, Duckworth WC 1983 Partial characterization of an endogenous inhibitor of a calcium-dependent form of insulin protease. Biochem Biophys Res Commun 116:195-203
-
(1983)
Biochem Biophys Res Commun
, vol.116
, pp. 195-203
-
-
Ryan, M.P.1
Duckworth, W.C.2
-
134
-
-
0021967528
-
Physical characterization of the cloned protease III gene from Escherichia coli K-12
-
Dykstra CC, Kushner SR 1985 Physical characterization of the cloned protease III gene from Escherichia coli K-12. J Bacteriol 163: 1055-1059
-
(1985)
J Bacteriol
, vol.163
, pp. 1055-1059
-
-
Dykstra, C.C.1
Kushner, S.R.2
-
135
-
-
0018379064
-
Purification and characterization of protease III from Escherichia coli
-
Cheng YE, Zipser D 1979 Purification and characterization of protease III from Escherichia coli. J Biol Chem 254:4698-4706
-
(1979)
J Biol Chem
, vol.254
, pp. 4698-4706
-
-
Cheng, Y.E.1
Zipser, D.2
-
136
-
-
0026800773
-
Comparison of the enzymatic and biochemical properties of human insulin-degrading enzyme and Escherichia coli protease III
-
Ding L, Becker AB, Suzuki A, Roth RA 1992 Comparison of the enzymatic and biochemical properties of human insulin-degrading enzyme and Escherichia coli protease III. J Biol Chem 267:2414-2420
-
(1992)
J Biol Chem
, vol.267
, pp. 2414-2420
-
-
Ding, L.1
Becker, A.B.2
Suzuki, A.3
Roth, R.A.4
-
137
-
-
0027479821
-
Evolutionary families of peptidases
-
Rawlings ND, Barrett AJ 1993 Evolutionary families of peptidases. Biochem J 290:205-218
-
(1993)
Biochem J
, vol.290
, pp. 205-218
-
-
Rawlings, N.D.1
Barrett, A.J.2
-
138
-
-
0025828357
-
Homologues of insulinase, a new superfamily of metalloendopeptidases
-
Rawlings ND, Barrett AJ 1991 Homologues of insulinase, a new superfamily of metalloendopeptidases. Biochem J 275:389-391
-
(1991)
Biochem J
, vol.275
, pp. 389-391
-
-
Rawlings, N.D.1
Barrett, A.J.2
-
139
-
-
0028587344
-
Identification of zinc ligands of the insulin-degrading enzyme
-
Periman RK, Rosner MR 1994 Identification of zinc ligands of the insulin-degrading enzyme. J Biol Chem 269:33140-33145
-
(1994)
J Biol Chem
, vol.269
, pp. 33140-33145
-
-
Periman, R.K.1
Rosner, M.R.2
-
140
-
-
0025160114
-
Identification of residues in the insulin molecule important for binding to insulin-degrading enzyme
-
Affholter JA, Casciere MA, Bayne ML, Brange J, Casaretto M, Roth RA 1990 Identification of residues in the insulin molecule important for binding to insulin-degrading enzyme. Biochemistry 29:7727-7733
-
(1990)
Biochemistry
, vol.29
, pp. 7727-7733
-
-
Affholter, J.A.1
Casciere, M.A.2
Bayne, M.L.3
Brange, J.4
Casaretto, M.5
Roth, R.A.6
-
141
-
-
0026028167
-
Purification and properties of a membrane-bound insulin binding protein, a putative receptor, from Neurospora crassa
-
Kole HK, Muthukumar G, Lenard J 1991 Purification and properties of a membrane-bound insulin binding protein, a putative receptor, from Neurospora crassa. Biochemistry 30:682-688
-
(1991)
Biochemistry
, vol.30
, pp. 682-688
-
-
Kole, H.K.1
Muthukumar, G.2
Lenard, J.3
-
142
-
-
0026985165
-
Characterization and partial purification of an insulinase from Neurospora crassa
-
Kole HK, Smith DR, Lenard J 1992 Characterization and partial purification of an insulinase from Neurospora crassa. Arch Biochem Biophys 297:199-204
-
(1992)
Arch Biochem Biophys
, vol.297
, pp. 199-204
-
-
Kole, H.K.1
Smith, D.R.2
Lenard, J.3
-
143
-
-
0029141783
-
A periplasmic insulin-cleaving proteinase (ICP) from Acinetobacter calcoaceticus sharing properties with protease III from Escherichia coli and IDF from eucaryotes
-
Fricke B, Betz R, Friebe S 1995 A periplasmic insulin-cleaving proteinase (ICP) from Acinetobacter calcoaceticus sharing properties with protease III from Escherichia coli and IDF from eucaryotes. J Basic Microbiol 35:21-31
-
(1995)
J Basic Microbiol
, vol.35
, pp. 21-31
-
-
Fricke, B.1
Betz, R.2
Friebe, S.3
-
144
-
-
0025119656
-
Insulin-degrading enzyme: Stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes
-
Affholter JA, Hsieh CL, Francke U, Roth RA 1990 Insulin-degrading enzyme: stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes. Mol Endocrinol 4:1125-1135
-
(1990)
Mol Endocrinol
, vol.4
, pp. 1125-1135
-
-
Affholter, J.A.1
Hsieh, C.L.2
Francke, U.3
Roth, R.A.4
-
145
-
-
0028216847
-
Cellular distribution of insulin-degrading enzyme gene expression: Comparison with insulin and insulin-like growth factor receptors
-
Bondy CA, Zhou J, Chin E, Reinhardt RR, Roth RA 1994 Cellular distribution of insulin-degrading enzyme gene expression: comparison with insulin and insulin-like growth factor receptors. J Clin Invest 93:966-973
-
(1994)
J Clin Invest
, vol.93
, pp. 966-973
-
-
Bondy, C.A.1
Zhou, J.2
Chin, E.3
Reinhardt, R.R.4
Roth, R.A.5
-
146
-
-
0027452730
-
Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues
-
Kuo WL, Montag AG, Rosner MR 1993 Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues. Endocrinology 132:604-611
-
(1993)
Endocrinology
, vol.132
, pp. 604-611
-
-
Kuo, W.L.1
Montag, A.G.2
Rosner, M.R.3
-
147
-
-
0027964969
-
Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line
-
Kuo WL, Gehm BD, Rosner MR, Li W, Keller G 1994 Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line. J Biol Chem 269:22599-22606
-
(1994)
J Biol Chem
, vol.269
, pp. 22599-22606
-
-
Kuo, W.L.1
Gehm, B.D.2
Rosner, M.R.3
Li, W.4
Keller, G.5
-
148
-
-
0027410472
-
The rat insulin degrading enzyme: Molecular cloning and characterization of tissue-specific transcripts
-
Baumeister H, Muller D, Rehbein M, Richter D 1993 The rat insulin degrading enzyme: molecular cloning and characterization of tissue-specific transcripts. FEBS Lett 317:250-254
-
(1993)
FEBS Lett
, vol.317
, pp. 250-254
-
-
Baumeister, H.1
Muller, D.2
Rehbein, M.3
Richter, D.4
-
149
-
-
0026527618
-
Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver
-
Ogawa W, Shii K, Yonezawa K, Baba S, Yokono K 1992 Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver. J Biol Chem 267:1310-1316
-
(1992)
J Biol Chem
, vol.267
, pp. 1310-1316
-
-
Ogawa, W.1
Shii, K.2
Yonezawa, K.3
Baba, S.4
Yokono, K.5
-
150
-
-
0021333892
-
Partial purification and characterization of insulin protease and its inrracellular inhibitor from rat liver
-
McKenzie RA, Burghen GA 1984 Partial purification and characterization of insulin protease and its inrracellular inhibitor from rat liver. Arch Biochem Biophys 229:604-611
-
(1984)
Arch Biochem Biophys
, vol.229
, pp. 604-611
-
-
McKenzie, R.A.1
Burghen, G.A.2
-
151
-
-
0019352996
-
Insulin degradation in serum of a patient with apparent insulin resistance
-
Misbin RI, Almira EC, Cleman MW 1981 Insulin degradation in serum of a patient with apparent insulin resistance. J Clin Endocrinol Metab 52:177-180
-
(1981)
J Clin Endocrinol Metab
, vol.52
, pp. 177-180
-
-
Misbin, R.I.1
Almira, E.C.2
Cleman, M.W.3
-
152
-
-
0028024153
-
Identification and isolation of a cytosolic proteolytic complex containing insulin degrading enzyme and the multicatalytic proteinase
-
Bennett RG, Hamel FG, Duckworth WC 1994 Identification and isolation of a cytosolic proteolytic complex containing insulin degrading enzyme and the multicatalytic proteinase. Biochem Biophys Res Commun 202:1047-1053
-
(1994)
Biochem Biophys Res Commun
, vol.202
, pp. 1047-1053
-
-
Bennett, R.G.1
Hamel, F.G.2
Duckworth, W.C.3
-
153
-
-
0018099711
-
Insulin and glucagon binding and degradation by the kidney cell membrane
-
Duckworth WC 1978 Insulin and glucagon binding and degradation by the kidney cell membrane. Endocrinology 102:1766-1774
-
(1978)
Endocrinology
, vol.102
, pp. 1766-1774
-
-
Duckworth, W.C.1
-
154
-
-
0018763489
-
Insulin degradation by liver cell membranes
-
Duckworth WC 1979 Insulin degradation by liver cell membranes. Endocrinology 104:1758-1764
-
(1979)
Endocrinology
, vol.104
, pp. 1758-1764
-
-
Duckworth, W.C.1
-
155
-
-
0018581619
-
Insulin-degrading activity of plasma membranes from rat skeletal muscle: Its isolation, characterization, and biologic significance
-
Yokono K, Imamura Y, Sakai H, Baba S 1979 Insulin-degrading activity of plasma membranes from rat skeletal muscle: its isolation, characterization, and biologic significance. Diabetes 28:810-817
-
(1979)
Diabetes
, vol.28
, pp. 810-817
-
-
Yokono, K.1
Imamura, Y.2
Sakai, H.3
Baba, S.4
-
156
-
-
0020201977
-
Identification of insulin-degrading enzyme on the surface of cultured human lymphocytes, rat hepatoma cells, and primary cultures of rat hepatocytes
-
Yokono K, Roth RA, Baba S 1982 Identification of insulin-degrading enzyme on the surface of cultured human lymphocytes, rat hepatoma cells, and primary cultures of rat hepatocytes. Endocrinology 111:1102-1108
-
(1982)
Endocrinology
, vol.111
, pp. 1102-1108
-
-
Yokono, K.1
Roth, R.A.2
Baba, S.3
-
157
-
-
0021353578
-
Degradation of insulin by isolated mouse pancreatic acini: Evidence for cell surface protease activity
-
Goldfine ID, Williams JA, Bailey AC, Wong KY, Iwamoto Y, Yokono K, Baba S, Rother RA 1984 Degradation of insulin by isolated mouse pancreatic acini: evidence for cell surface protease activity. Diabetes 33:64-72
-
(1984)
Diabetes
, vol.33
, pp. 64-72
-
-
Goldfine, I.D.1
Williams, J.A.2
Bailey, A.C.3
Wong, K.Y.4
Iwamoto, Y.5
Yokono, K.6
Baba, S.7
Rother, R.A.8
-
158
-
-
0029024878
-
Degradation of the cleaved leader peptide of thiolase by a peroxisomal proteinase
-
Authier F, Bergeron JJ, Ou WJ, Rachubinski RA, Posner BI, Walton PA 1995 Degradation of the cleaved leader peptide of thiolase by a peroxisomal proteinase. Proc Natl Acad Sci USA 92:3859-3863
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3859-3863
-
-
Authier, F.1
Bergeron, J.J.2
Ou, W.J.3
Rachubinski, R.A.4
Posner, B.I.5
Walton, P.A.6
-
159
-
-
1842326239
-
Insulin degrading enzyme (IDE) in renal proximal tubules
-
Rabkin R, Birn H, Shi J, Roth R, Christensen E 1992 Insulin degrading enzyme (IDE) in renal proximal tubules. Diabetes 41: 15A
-
(1992)
Diabetes
, vol.41
-
-
Rabkin, R.1
Birn, H.2
Shi, J.3
Roth, R.4
Christensen, E.5
-
160
-
-
0030787591
-
Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation
-
Chesneau V, Perlman RK, Li W, Keller GA, Rosner MR 1997 Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation. Endocrinology 138:3444-3451
-
(1997)
Endocrinology
, vol.138
, pp. 3444-3451
-
-
Chesneau, V.1
Perlman, R.K.2
Li, W.3
Keller, G.A.4
Rosner, M.R.5
-
161
-
-
0016165036
-
Insulin and glucagon degradation by the same enzyme
-
Duckworth WC, Kitabchi AE 1974 Insulin and glucagon degradation by the same enzyme. Diabetes 23:536-543
-
(1974)
Diabetes
, vol.23
, pp. 536-543
-
-
Duckworth, W.C.1
Kitabchi, A.E.2
-
162
-
-
0025809406
-
Regulation of insulin, epidermal growth factor, and transforming growth factor-α levels by growth factor degrading enzymes
-
Gehm BD, Rosner MR 1991Regulation of insulin, epidermal growth factor, and transforming growth factor-α levels by growth factor degrading enzymes. Endocrinology 128:1603-1609
-
(1991)
Endocrinology
, vol.128
, pp. 1603-1609
-
-
Gehm, B.D.1
Rosner, M.R.2
-
163
-
-
0021195660
-
Degradation of insulin-like growth factors I and II by a human insulin degrading enzyme
-
Roth RA, Mesirow ML, Yokono K, Baba S 1984 Degradation of insulin-like growth factors I and II by a human insulin degrading enzyme. Endocr Res 10:101-112
-
(1984)
Endocr Res
, vol.10
, pp. 101-112
-
-
Roth, R.A.1
Mesirow, M.L.2
Yokono, K.3
Baba, S.4
-
164
-
-
0017283046
-
Inhibition of insulin degradation by nonsuppressible insulin-like activity
-
Burghen GA, Duckworth WC, Kitabchi AE, Solomon SS, Poffenbarger PL 1976 Inhibition of insulin degradation by nonsuppressible insulin-like activity. J Clin Invest 57:1089-1093
-
(1976)
J Clin Invest
, vol.57
, pp. 1089-1093
-
-
Burghen, G.A.1
Duckworth, W.C.2
Kitabchi, A.E.3
Solomon, S.S.4
Poffenbarger, P.L.5
-
165
-
-
0025987157
-
Atrial natriuretic peptide (ANP) is a high-affinity substrate for rat insulin-degrading enzyme
-
Muller D, Baumeister H, Buck F, Richter D 1991 Atrial natriuretic peptide (ANP) is a high-affinity substrate for rat insulin-degrading enzyme. Eur J Biochem 202:285-292
-
(1991)
Eur J Biochem
, vol.202
, pp. 285-292
-
-
Muller, D.1
Baumeister, H.2
Buck, F.3
Richter, D.4
-
166
-
-
0030951993
-
Identification of the cleavage sites of transforming growth factor-alpha by insulin degrading enzymes
-
Hamel FG, Gehm BD, Rosner RG, Duckworth WC 1997 Identification of the cleavage sites of transforming growth factor-alpha by insulin degrading enzymes. Biochim Biophys Acta 1338:207-214
-
(1997)
Biochim Biophys Acta
, vol.1338
, pp. 207-214
-
-
Hamel, F.G.1
Gehm, B.D.2
Rosner, R.G.3
Duckworth, W.C.4
-
167
-
-
0015121943
-
Direct measurement of proinsulin in human plasma by the use of an insulin degrading enzyme
-
Kitabchi AE, Duckworth WC, Brush JS, Heinemann M 1971 Direct measurement of proinsulin in human plasma by the use of an insulin degrading enzyme. J Clin Invest 50:1792-1799
-
(1971)
J Clin Invest
, vol.50
, pp. 1792-1799
-
-
Kitabchi, A.E.1
Duckworth, W.C.2
Brush, J.S.3
Heinemann, M.4
-
169
-
-
0015817541
-
Substrate studies for insulin specific protease
-
Baskin FK, Kitabchi AE 1973 Substrate studies for insulin specific protease. Eur J Biochem 37:489-496
-
(1973)
Eur J Biochem
, vol.37
, pp. 489-496
-
-
Baskin, F.K.1
Kitabchi, A.E.2
-
170
-
-
0024286090
-
Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster
-
Garcia JV, Fenton BW, Rosner MR 1988 Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster. Biochemistry 27:4237-4244
-
(1988)
Biochemistry
, vol.27
, pp. 4237-4244
-
-
Garcia, J.V.1
Fenton, B.W.2
Rosner, M.R.3
-
171
-
-
0022312871
-
Identification of a novel receptor in Drosophila for both epidermal growth factor and insulin
-
Thompson KL, Decker SJ, Rosner MR 1985 Identification of a novel receptor in Drosophila for both epidermal growth factor and insulin. Proc Natl Acad Sci USA 82:8443-8447
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 8443-8447
-
-
Thompson, K.L.1
Decker, S.J.2
Rosner, M.R.3
-
172
-
-
0023371935
-
Characterization of a Drosophila protein that binds both epidermal growth factor and insulin-related growth factors
-
Garcia JV, Stoppelli MP, Thompson KL, Decker SJ, Rosner MR 1987 Characterization of a Drosophila protein that binds both epidermal growth factor and insulin-related growth factors. J Cell Biol 105:449-456
-
(1987)
J Cell Biol
, vol.105
, pp. 449-456
-
-
Garcia, J.V.1
Stoppelli, M.P.2
Thompson, K.L.3
Decker, S.J.4
Rosner, M.R.5
-
173
-
-
0024525751
-
An insulin epidermal growth factor-binding protein from Drosophila has insulin-degrading activity
-
Garcia JV, Stopelli MP, Decker SJ, Rosner MR 1989 An insulin epidermal growth factor-binding protein from Drosophila has insulin-degrading activity. J Cell Biol 108:177-182
-
(1989)
J Cell Biol
, vol.108
, pp. 177-182
-
-
Garcia, J.V.1
Stopelli, M.P.2
Decker, S.J.3
Rosner, M.R.4
-
174
-
-
0025916307
-
Purification of a protease in red blood cells that degrades oxidatively damaged haemoglobin
-
Fagan JM, Waxman L 1991 Purification of a protease in red blood cells that degrades oxidatively damaged haemoglobin. Biochem J 277:779-786
-
(1991)
Biochem J
, vol.277
, pp. 779-786
-
-
Fagan, J.M.1
Waxman, L.2
-
175
-
-
0029843563
-
Identification of y endorphin-generating enzyme as insulin-degrading enzyme
-
Safavi A, Miller BC, Cottam L, Hersh LB 1996 Identification of y endorphin-generating enzyme as insulin-degrading enzyme. Biochemistry 35:14318-14325
-
(1996)
Biochemistry
, vol.35
, pp. 14318-14325
-
-
Safavi, A.1
Miller, B.C.2
Cottam, L.3
Hersh, L.B.4
-
176
-
-
0028176821
-
Alzheimer's β-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
-
Kurochkin IV, Goto S 1994 Alzheimer's β-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS Lett 345:33-37
-
(1994)
FEBS Lett
, vol.345
, pp. 33-37
-
-
Kurochkin, I.V.1
Goto, S.2
-
178
-
-
0031044352
-
Degradation of Alzheimer's β-amy loid protein by human and rat brain peptidases: Involvement of insulin-degrading enzyme
-
McDermott JR, Gibson AM 1997 Degradation of Alzheimer's β-amy loid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme. Neurochem Res 22:49-56
-
(1997)
Neurochem Res
, vol.22
, pp. 49-56
-
-
McDermott, J.R.1
Gibson, A.M.2
-
179
-
-
0022405273
-
Receptor binding and biological potency of several split forms (conversion intermediates) of human proinsulin: Studies in cultured IM-9 lymphocytes and in vitro in rats
-
Peavy DE, Brunner MR, Duckworth WC, Hooker CS, Frank BH 1985 Receptor binding and biological potency of several split forms (conversion intermediates) of human proinsulin: studies in cultured IM-9 lymphocytes and in vitro in rats. J Biol Chem 260:13989-13994
-
(1985)
J Biol Chem
, vol.260
, pp. 13989-13994
-
-
Peavy, D.E.1
Brunner, M.R.2
Duckworth, W.C.3
Hooker, C.S.4
Frank, B.H.5
-
180
-
-
0018750519
-
Insulin resistance due to massive destruction of subcutaneous insulin
-
Faulsen EP, Courtney JW, Duckworth WC 1979 Insulin resistance due to massive destruction of subcutaneous insulin. Diabetes 28: 640-645
-
(1979)
Diabetes
, vol.28
, pp. 640-645
-
-
Faulsen, E.P.1
Courtney, J.W.2
Duckworth, W.C.3
-
181
-
-
0022642934
-
In search of the subcutaneous insulin degradation syndrome
-
Schade DS, Duckworth WC 1986 In search of the subcutaneous insulin degradation syndrome. N Engl J Med 315:147-153
-
(1986)
N Engl J Med
, vol.315
, pp. 147-153
-
-
Schade, D.S.1
Duckworth, W.C.2
-
184
-
-
0025017837
-
Proteolytic degradation of human recombinant proinsulin/ insulin by sera from acute pancreatitis patients and complete inhibition by Eglin-C
-
Lau PP, Van Handel M, Larvin M, McMahon MJ, Geokas MC 1990 Proteolytic degradation of human recombinant proinsulin/ insulin by sera from acute pancreatitis patients and complete inhibition by Eglin-C. Pancreas 5:17-26
-
(1990)
Pancreas
, vol.5
, pp. 17-26
-
-
Lau, P.P.1
Van Handel, M.2
Larvin, M.3
McMahon, M.J.4
Geokas, M.C.5
-
186
-
-
0025198488
-
3H1 and primary skeletal muscle cells and the activity of their endogenous insulin-degrading enzyme are inhibited by the same metalloendoprotease inhibitors
-
3H1 and primary skeletal muscle cells and the activity of their endogenous insulin-degrading enzyme are inhibited by the same metalloendoprotease inhibitors. J Cell Biochem 44:137-151
-
(1990)
J Cell Biochem
, vol.44
, pp. 137-151
-
-
Kayalar, C.1
Wong, W.T.2
Hendrickson, L.3
-
187
-
-
0023573995
-
Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin. A loop-specific T cells
-
Naquet P, Ellis J, Singh B, Hodges RS, Delovitch TL 1987 Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin. A loop-specific T cells. J Immunol 139:3955-3963
-
(1987)
J Immunol
, vol.139
, pp. 3955-3963
-
-
Naquet, P.1
Ellis, J.2
Singh, B.3
Hodges, R.S.4
Delovitch, T.L.5
-
188
-
-
0024324522
-
Processing and presentation of insulin. II. Evidence for intracellular, plasma membrane-associated and extracellular degradation of human insulin by antigen presenting B cells
-
Semple J, Ellis J, Delovitch T 1989 Processing and presentation of insulin. II. Evidence for intracellular, plasma membrane-associated and extracellular degradation of human insulin by antigen presenting B cells. J Immunol 142:4184-4193
-
(1989)
J Immunol
, vol.142
, pp. 4184-4193
-
-
Semple, J.1
Ellis, J.2
Delovitch, T.3
-
189
-
-
0024166614
-
Pathways of processing of insulin by antigen-presenting cells
-
Delovitch T, Semple W, Naquet P, Bernard N, Ellis J, Champagne P, Phillips M 1988 Pathways of processing of insulin by antigen-presenting cells. Immunol Rev 106:195-222
-
(1988)
Immunol Rev
, vol.106
, pp. 195-222
-
-
Delovitch, T.1
Semple, W.2
Naquet, P.3
Bernard, N.4
Ellis, J.5
Champagne, P.6
Phillips, M.7
-
190
-
-
0026661263
-
Processing and presentation of insulin. III. Insulin degrading enzyme: A neutral metalloendoproteinase that is non-homologous to classical endoproteinases mediates the processing of insulin epitopes for helper T cells
-
Semple JW, Lang Y, Speck ER, Delovitch TL 1992 Processing and presentation of insulin. III. Insulin degrading enzyme: a neutral metalloendoproteinase that is non-homologous to classical endoproteinases mediates the processing of insulin epitopes for helper T cells. Int Immunol 4:1161-1167
-
(1992)
Int Immunol
, vol.4
, pp. 1161-1167
-
-
Semple, J.W.1
Lang, Y.2
Speck, E.R.3
Delovitch, T.L.4
-
191
-
-
0028020331
-
Analysis of the spontaneous T cell response to insulin in NOD mice
-
Wegmann DR, Gill RG, Norbury-Glaser M, Schloot N, Daniel D 1994 Analysis of the spontaneous T cell response to insulin in NOD mice. J Autoimmun 7:833-843
-
(1994)
J Autoimmun
, vol.7
, pp. 833-843
-
-
Wegmann, D.R.1
Gill, R.G.2
Norbury-Glaser, M.3
Schloot, N.4
Daniel, D.5
-
192
-
-
0028914351
-
Epitope specificity, cytokine production profile and diabetogeneic activity of insulin-specific T cell clones isolated from NOD mice
-
Daniel D, Gill RG, Schloot N, Wegmann DR 1995 Epitope specificity, cytokine production profile and diabetogeneic activity of insulin-specific T cell clones isolated from NOD mice. Eur J Immunol 25:1056-1062
-
(1995)
Eur J Immunol
, vol.25
, pp. 1056-1062
-
-
Daniel, D.1
Gill, R.G.2
Schloot, N.3
Wegmann, D.R.4
-
193
-
-
0031003690
-
Autoimmune islet damage mediated by insulin-specific T cells
-
Crawford M, Daniel D, Wegmann DR, Yang H, Gill RG 1997 Autoimmune islet damage mediated by insulin-specific T cells. Transplant Proc 29:758-759
-
(1997)
Transplant Proc
, vol.29
, pp. 758-759
-
-
Crawford, M.1
Daniel, D.2
Wegmann, D.R.3
Yang, H.4
Gill, R.G.5
-
194
-
-
0030069688
-
Protection of nonobese diabetic mice from diabetes by intranasal of subcutaneous administration of insulin peptide B-(9-23)
-
Daniel D, Wegmann DR 1996 Protection of nonobese diabetic mice from diabetes by intranasal of subcutaneous administration of insulin peptide B-(9-23). Proc Natl Acad Sci USA 93:956-960
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 956-960
-
-
Daniel, D.1
Wegmann, D.R.2
-
195
-
-
0028151340
-
A yeast gene necessary for bud-site selection encodes a protein similar to insulin-degrading enzymes
-
Fujita A, Oka C, Arikawa Y, Katagal T, Tonouchi A, Kuhara S, Misumi Y 1994 A yeast gene necessary for bud-site selection encodes a protein similar to insulin-degrading enzymes. Nature 372: 567-570
-
(1994)
Nature
, vol.372
, pp. 567-570
-
-
Fujita, A.1
Oka, C.2
Arikawa, Y.3
Katagal, T.4
Tonouchi, A.5
Kuhara, S.6
Misumi, Y.7
-
196
-
-
0028879135
-
Role of yeast insulin-degrading enzyme homologs in propherotnone processing and bud site selection
-
Adames N, Blandell K, Ashby MN, Boone C 1995 Role of yeast insulin-degrading enzyme homologs in propherotnone processing and bud site selection. Science 270:464-467
-
(1995)
Science
, vol.270
, pp. 464-467
-
-
Adames, N.1
Blandell, K.2
Ashby, M.N.3
Boone, C.4
-
197
-
-
0028173765
-
N-Arginine dibasic convertase, a metalloendopeptidase as a prototype of a class of processing enzymes
-
Pierotti AR, Prat A, Chesneau V, Gaudoux F, Leseney AM, Foulon T, Cohen P1994 N-Arginine dibasic convertase, a metalloendopeptidase as a prototype of a class of processing enzymes. Proc Natl Acad Sci USA 91:6078-6082
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6078-6082
-
-
Pierotti, A.R.1
Prat, A.2
Chesneau, V.3
Gaudoux, F.4
Leseney, A.M.5
Foulon, T.6
Cohen, P.7
-
198
-
-
7844249168
-
Purification and partial characterization of the liver membrane endopeptidase which transforms glucagon into glucagon (19-29)
-
Blache P, Kervran A, Duckworth WC, Bataille D 1992 Purification and partial characterization of the liver membrane endopeptidase which transforms glucagon into glucagon (19-29). Biomed Res 13:51-55
-
(1992)
Biomed Res
, vol.13
, pp. 51-55
-
-
Blache, P.1
Kervran, A.2
Duckworth, W.C.3
Bataille, D.4
-
199
-
-
0023128223
-
A glucagon fragment is responsible for the inhibition of the liver Ca2+ pump by glucagon
-
Mallat A, Pavoine C, Dufour M, Lotersztajn S, Bataille D, Pecker F 1987 A glucagon fragment is responsible for the inhibition of the liver Ca2+ pump by glucagon. Nature 325:620-622
-
(1987)
Nature
, vol.325
, pp. 620-622
-
-
Mallat, A.1
Pavoine, C.2
Dufour, M.3
Lotersztajn, S.4
Bataille, D.5
Pecker, F.6
-
200
-
-
0027373789
-
Endopeptidase from rat liver membranes, which generates miniglucagon from glucagon
-
Blache P, Kervran A, Le-Nguyen D, Dufour M, Cohen-Sodal A, Duckworth W, Bataille D 1993 Endopeptidase from rat liver membranes, which generates miniglucagon from glucagon. J Biol Chem 268:21748-21753
-
(1993)
J Biol Chem
, vol.268
, pp. 21748-21753
-
-
Blache, P.1
Kervran, A.2
Le-Nguyen, D.3
Dufour, M.4
Cohen-Sodal, A.5
Duckworth, W.6
Bataille, D.7
-
202
-
-
0343223470
-
Role of the biodegradation process in the action of insulin. A proposal for a model consisting of sulfhydryl-disulfide interchange reacter and proteolysis
-
Brandenburg D, Wollmer A (eds) Walter de Grayter, Berlin
-
Varandani PT 1980 Role of the biodegradation process in the action of insulin. A proposal for a model consisting of sulfhydryl-disulfide interchange reacter and proteolysis. In: Brandenburg D, Wollmer A (eds) Insulin, Chemistry, Structure and Function of Insulin and Related Hormones. Walter de Grayter, Berlin, pp 475-482
-
(1980)
Insulin, Chemistry, Structure and Function of Insulin and Related Hormones
, pp. 475-482
-
-
Varandani, P.T.1
-
203
-
-
0022401035
-
Studies on the formation of interchain disulfide bonds in newly synthesized bovine prolactin
-
Kaderbhai MA, Austen BM 1985 Studies on the formation of interchain disulfide bonds in newly synthesized bovine prolactin. Eur J Biochem 153:167-178
-
(1985)
Eur J Biochem
, vol.153
, pp. 167-178
-
-
Kaderbhai, M.A.1
Austen, B.M.2
-
204
-
-
0019815999
-
Role of disulfide interchange enzyme in immunoglobulin synthesis
-
Roth RA, Koshland ME 1981 Role of disulfide interchange enzyme in immunoglobulin synthesis. Biochemistry 20:6594-6599
-
(1981)
Biochemistry
, vol.20
, pp. 6594-6599
-
-
Roth, R.A.1
Koshland, M.E.2
-
205
-
-
0024337857
-
Protein disulfide isomerase: Multiple roles in the modification of nascent secretory proteins
-
Freedman RB 1989 Protein disulfide isomerase: multiple roles in the modification of nascent secretory proteins. Cell 57:1069-1072
-
(1989)
Cell
, vol.57
, pp. 1069-1072
-
-
Freedman, R.B.1
-
206
-
-
0026731788
-
Minireview: Protein disulfide isomerase
-
Noiva R, Lennarz W 1992 Minireview: protein disulfide isomerase. J Biol Chem 267:3553-3556
-
(1992)
J Biol Chem
, vol.267
, pp. 3553-3556
-
-
Noiva, R.1
Lennarz, W.2
-
207
-
-
0343409409
-
Insulin degrading enzyme
-
Cuatrecasas P, Jacobs S (eds) Springer-Verlag Press, Berlin
-
Duckworth WC 1990 Insulin degrading enzyme. In: Cuatrecasas P, Jacobs S (eds) The Handbook of Experimental Pharmacology. Springer-Verlag Press, Berlin, vol 92:143-165
-
(1990)
The Handbook of Experimental Pharmacology
, vol.92
, pp. 143-165
-
-
Duckworth, W.C.1
-
208
-
-
0021797541
-
Degradation of endocytosed insulin in rat liver is mediated by low density vesicles
-
Pease RJ, Smith GD, Peters TJ 1985 Degradation of endocytosed insulin in rat liver is mediated by low density vesicles. Biochem J 228:137-146
-
(1985)
Biochem J
, vol.228
, pp. 137-146
-
-
Pease, R.J.1
Smith, G.D.2
Peters, T.J.3
-
209
-
-
0022539939
-
Differential and analytical subfractionation of rat liver components internalizing insulin and prolactin
-
Bergeron JJM, Searle N, Khan MN, Posner BI 1986 Differential and analytical subfractionation of rat liver components internalizing insulin and prolactin. Biochemistry 25:1756-1764
-
(1986)
Biochemistry
, vol.25
, pp. 1756-1764
-
-
Bergeron, J.J.M.1
Searle, N.2
Khan, M.N.3
Posner, B.I.4
-
210
-
-
0021881087
-
125I asioalofetuin degradation by the isolated, perfused rat liver and isolated rat hepatocytes
-
125I asioalofetuin degradation by the isolated, perfused rat liver and isolated rat hepatocytes. Diabetes 34:446-451
-
(1985)
Diabetes
, vol.34
, pp. 446-451
-
-
Ward, W.F.1
Moss, A.L.2
-
211
-
-
0026541299
-
Substrates and signalling complexes: The tortured path to insulin action
-
Roth RA, Zhang B, Chin JE, Kovacina K 1992 Substrates and signalling complexes: the tortured path to insulin action. J Cell Biochem 48:12-18
-
(1992)
J Cell Biochem
, vol.48
, pp. 12-18
-
-
Roth, R.A.1
Zhang, B.2
Chin, J.E.3
Kovacina, K.4
-
212
-
-
0027267497
-
Receptor accessory factor enhances specific DNA binding of androgen and glucocorticoid receptors
-
Kupfer S, Marschke K, Wilson E, French F 1993 Receptor accessory factor enhances specific DNA binding of androgen and glucocorticoid receptors. J Biol Chem 268:17519-17527
-
(1993)
J Biol Chem
, vol.268
, pp. 17519-17527
-
-
Kupfer, S.1
Marschke, K.2
Wilson, E.3
French, F.4
-
213
-
-
0027983795
-
Androgen and glucocorticoid receptors interact with insulin degrading enzyme
-
Kupfer SR, Wilson EM, French FS 1994 Androgen and glucocorticoid receptors interact with insulin degrading enzyme. J Biol Chem 269:20622-20628
-
(1994)
J Biol Chem
, vol.269
, pp. 20622-20628
-
-
Kupfer, S.R.1
Wilson, E.M.2
French, F.S.3
-
214
-
-
0024819251
-
Glucocorticoid regulation of chloroquine non-sensitive insulin degradation in cultured fetal rat heaptocytes
-
Ali M, Plas C 1989 Glucocorticoid regulation of chloroquine non-sensitive insulin degradation in cultured fetal rat heaptocytes. J Biol Chem 264:20992-20997
-
(1989)
J Biol Chem
, vol.264
, pp. 20992-20997
-
-
Ali, M.1
Plas, C.2
-
215
-
-
0344450503
-
Insulin inhibition of fatty acid β-oxidation in isolated peroxisomes
-
Bennett RG, Hamel FG, Duckworth WC 1996 Insulin inhibition of fatty acid β-oxidation in isolated peroxisomes. Diabetes 45:310A
-
(1996)
Diabetes
, vol.45
-
-
Bennett, R.G.1
Hamel, F.G.2
Duckworth, W.C.3
-
216
-
-
0025032639
-
Modulation of kidney cell protein degradation by insulin
-
Tsao TC, Shi JD, Mortimore GE, Cragoe Jr EJ, Rabkin R 1990 Modulation of kidney cell protein degradation by insulin. J Lab Clin Med 116:369-376
-
(1990)
J Lab Clin Med
, vol.116
, pp. 369-376
-
-
Tsao, T.C.1
Shi, J.D.2
Mortimore, G.E.3
Cragoe Jr., E.J.4
Rabkin, R.5
-
217
-
-
0030989326
-
Insulin internalization and other signaling pathways in the pleiotropic effects of insulin
-
Smith RM, Harada S, Jarett L 1997 Insulin internalization and other signaling pathways in the pleiotropic effects of insulin. Int Rev Cytol 173:243-280
-
(1997)
Int Rev Cytol
, vol.173
, pp. 243-280
-
-
Smith, R.M.1
Harada, S.2
Jarett, L.3
-
218
-
-
0029037649
-
Pathophysiology of insulin resistance in human diseases
-
Reaven GM 1995 Pathophysiology of insulin resistance in human diseases. Physiol Rev 75:473-486
-
(1995)
Physiol Rev
, vol.75
, pp. 473-486
-
-
Reaven, G.M.1
-
219
-
-
0028904053
-
Insulin action and the insulin signaling network
-
Cheatham B, Kahn CR 1995 Insulin action and the insulin signaling network. Endocr Rev 16:117-142
-
(1995)
Endocr Rev
, vol.16
, pp. 117-142
-
-
Cheatham, B.1
Kahn, C.R.2
-
220
-
-
0020513164
-
Insulin-ricin B hybrid molecules mediate an insulin-associated effect on cells which do not bind insulin
-
Hofmann CA, Lotan RM, Ku WW, Oeltmann TN 1983 Insulin-ricin B hybrid molecules mediate an insulin-associated effect on cells which do not bind insulin. J Biol Chem 258:11774-11779
-
(1983)
J Biol Chem
, vol.258
, pp. 11774-11779
-
-
Hofmann, C.A.1
Lotan, R.M.2
Ku, W.W.3
Oeltmann, T.N.4
-
221
-
-
0024356726
-
Stimulation of protein synthesis in stage IV Xenopus oocytes by microinjected insulin
-
Miller DS 1989 Stimulation of protein synthesis in stage IV Xenopus oocytes by microinjected insulin. J Biol Chem 264:10438-10446
-
(1989)
J Biol Chem
, vol.264
, pp. 10438-10446
-
-
Miller, D.S.1
-
222
-
-
0024294350
-
Stimulation of RNA and protein synthesis by intracellular insulin
-
Miller DS 1988 Stimulation of RNA and protein synthesis by intracellular insulin. Science 240:506-509
-
(1988)
Science
, vol.240
, pp. 506-509
-
-
Miller, D.S.1
-
223
-
-
0025893171
-
Stimulation of protein synthesis by internalized insulin
-
Miller DS, Sykes DB 1991 Stimulation of protein synthesis by internalized insulin. J Cell Physiol 147:487-494
-
(1991)
J Cell Physiol
, vol.147
, pp. 487-494
-
-
Miller, D.S.1
Sykes, D.B.2
-
224
-
-
0028910938
-
A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules
-
Kovacsovics-Bankowski M, Rock KL 1995 A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science 267:243-246
-
(1995)
Science
, vol.267
, pp. 243-246
-
-
Kovacsovics-Bankowski, M.1
Rock, K.L.2
-
225
-
-
0020403436
-
Inhibition of intracellular proteolysis by insulin in isolated rat hepatocytes: Possible role of internalized hormone
-
Draznin B, Trowbridge M 1982 Inhibition of intracellular proteolysis by insulin in isolated rat hepatocytes: possible role of internalized hormone. J Biol Chem 257:11988-11993
-
(1982)
J Biol Chem
, vol.257
, pp. 11988-11993
-
-
Draznin, B.1
Trowbridge, M.2
-
226
-
-
0021350750
-
Selective effects of inhibitors of hormone processing on insulin action in isolated hepatocytes
-
Peavy DE, Edmondson JW, Duckworth WC 1984 Selective effects of inhibitors of hormone processing on insulin action in isolated hepatocytes. Endocrinology 114:753-760
-
(1984)
Endocrinology
, vol.114
, pp. 753-760
-
-
Peavy, D.E.1
Edmondson, J.W.2
Duckworth, W.C.3
-
227
-
-
0030442915
-
Insulin action in cultured human myoblasts: Contribution of different signalling pathways to regulation of glycogen synthesis
-
Hurel SJ, Rochford JJ, Borthwick AC, Wells AM, Vandenheede JR, Turnbull DM, Yeaman SJ 1996 Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis. Biochem J 320:871-877
-
(1996)
Biochem J
, vol.320
, pp. 871-877
-
-
Hurel, S.J.1
Rochford, J.J.2
Borthwick, A.C.3
Wells, A.M.4
Vandenheede, J.R.5
Turnbull, D.M.6
Yeaman, S.J.7
-
228
-
-
0024358334
-
Augmented mitogenesis and impaired metabolic signaling mediated by a truncated insulin receptor
-
Thies RS, Ullrich A, McClain DA 1989 Augmented mitogenesis and impaired metabolic signaling mediated by a truncated insulin receptor. J Biol Chem 264:12820-12825
-
(1989)
J Biol Chem
, vol.264
, pp. 12820-12825
-
-
Thies, R.S.1
Ullrich, A.2
McClain, D.A.3
-
229
-
-
0025372470
-
The insulin receptor with phenylalanine replacing tyrosine-1146 provides evidence for separate signals regulating cellular metabolism and growth
-
Wilden PA, Backer JM, Kahn CR, Cahill DA, Schroeder GJ, White MF 1990 The insulin receptor with phenylalanine replacing tyrosine-1146 provides evidence for separate signals regulating cellular metabolism and growth. Proc Natl Acad Sci USA 87:3358-3362
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3358-3362
-
-
Wilden, P.A.1
Backer, J.M.2
Kahn, C.R.3
Cahill, D.A.4
Schroeder, G.J.5
White, M.F.6
-
230
-
-
0030002820
-
The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis
-
Yenush L, Fernandez R, Myers MG, Grammer TC, Sun XJ, Blenis J, Pierce JH, Schlessinger J, White MF 1996 The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis. Mol Cell Biol 16: 2509-2517
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2509-2517
-
-
Yenush, L.1
Fernandez, R.2
Myers, M.G.3
Grammer, T.C.4
Sun, X.J.5
Blenis, J.6
Pierce, J.H.7
Schlessinger, J.8
White, M.F.9
-
231
-
-
0030851268
-
Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor
-
Ish-Shalom D, Christoffersen CT, Vorwerk P, Sacerdoti-Sierra N, Shymko RM, Naor D, De Meyts P 1997 Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor. Diabetologia 40:525-531
-
(1997)
Diabetologia
, vol.40
, pp. 525-531
-
-
Ish-Shalom, D.1
Christoffersen, C.T.2
Vorwerk, P.3
Sacerdoti-Sierra, N.4
Shymko, R.M.5
Naor, D.6
De Meyts, P.7
-
232
-
-
0029894805
-
Editorial: Insulin signaling network - Waiting for Copernicus
-
Draznin B 1996 Editorial: Insulin signaling network - Waiting for Copernicus. Endocrinology 137:2647-2648
-
(1996)
Endocrinology
, vol.137
, pp. 2647-2648
-
-
Draznin, B.1
-
233
-
-
0028102743
-
A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalycic proteinase
-
Duckworth WC, Bennett RG, Hamel FG 1994 A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalycic proteinase. J Biol Chem 269:24575-24580
-
(1994)
J Biol Chem
, vol.269
, pp. 24575-24580
-
-
Duckworth, W.C.1
Bennett, R.G.2
Hamel, F.G.3
-
234
-
-
0030953108
-
Characterization of the insulin inhibition of the peptidolytic activities of the insulin-degrading enzyme-proteasome complex
-
Bennett RG, Hamel FG, Duckworth WC 1997 Characterization of the insulin inhibition of the peptidolytic activities of the insulin-degrading enzyme-proteasome complex. Diabetes 46:197-203
-
(1997)
Diabetes
, vol.46
, pp. 197-203
-
-
Bennett, R.G.1
Hamel, F.G.2
Duckworth, W.C.3
-
235
-
-
0032539732
-
Insulin acts intracellulary on proteasomes through insulin-degrading enzyme
-
Duckworth WC, Bennett RG, Hamel FG 1998 Insulin acts intracellulary on proteasomes through insulin-degrading enzyme. Biochem Biophys Res Commun 244:390-398
-
(1998)
Biochem Biophys Res Commun
, vol.244
, pp. 390-398
-
-
Duckworth, W.C.1
Bennett, R.G.2
Hamel, F.G.3
-
236
-
-
0029058620
-
Chloroquine does not exert insulin-like actions on human forearm muscle metabolism
-
Barrett EJ, Jahn LA, Oliveras EM, Fryburg DA 1995 Chloroquine does not exert insulin-like actions on human forearm muscle metabolism. Am J Physiol 268:E820-824
-
(1995)
Am J Physiol
, vol.268
-
-
Barrett, E.J.1
Jahn, L.A.2
Oliveras, E.M.3
Fryburg, D.A.4
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