Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families

Journal of Biological Chemistry

Volumn 282, Issue 11, 2007, Pages 7825-7832

  Kim, Minji ^a   Hersh, Louis B ^b   Leissring, Malcolm A ^a   Ingelsson, Martin ^a   Matsui, Toshifumi ^a   Farris, Wesley ^a   Lu, Alice ^a   Hyman, Bradley T ^a   Selkoe, Dennis J ^a   Bertram, Lars ^a   Tanzi, Rudolph E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE (AD); GENETIC LINKAGE; INSULIN-DEGRADING ENZYME (IDE); SENILE PLAQUES;

CATALYST ACTIVITY; CHROMOSOMES; DISEASES; GENE EXPRESSION; INSULIN; RNA;

ENZYMES;

INSULINASE; MESSENGER RNA; INSULIN;

AGED; ALZHEIMER DISEASE; ARTICLE; CATALYST; CHROMOSOME 10; CLINICAL ARTICLE; FEMALE; GENETIC LINKAGE; HUMAN; MALE; MENTAL HEALTH SERVICE; MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STATISTICAL SIGNIFICANCE; BRAIN; CATALYSIS; FAMILY HEALTH; GENETICS; LYMPHOCYTE; METABOLISM; MIDDLE AGED; PATHOLOGY; PEDIGREE; ULTRASTRUCTURE;

AGED; ALZHEIMER DISEASE; BRAIN; CATALYSIS; CHROMOSOMES, HUMAN, PAIR 10; FAMILY HEALTH; FEMALE; HUMANS; INSULIN; INSULYSIN; LINKAGE (GENETICS); LYMPHOCYTES; MALE; MIDDLE AGED; MUTATION; PEDIGREE;

EID: 34247244627     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M609168200     Document Type: Article

References (47)

1. Selkoe, D. J. (2001) Neuron 32, 177-180
2. Ingelsson, M., Fukumoto, H., Newell, K. L., Growdon, J. H., Hedley-Whyte, E. T., Frosch, M. P., Albert, M. S., Hyman, B. T., and Irizarry, M. C. (2004) Neurology 62, 925-931
3. Tanzi, R. E., and Bertram, L. (2005) Cell 120, 545-555
4. Gatz, M., Reynolds, C. A., Fratiglioni, L., Johansson, B., Mortimer, J. A., Berg, S., Fiske, A., and Pedersen, N. L. (2006) Arch. Gen. Psychiatry 63, 168-174
5. Strittmatter, W. J., Saunders, A. M., Schmechel, D., Pericak-Vance, M., Enghild, J., Salvesen, G. S., and Roses, A. D. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 1977-1981
6. Savage, M. J., Trusko, S. P., Howland, D. S., Pinsker, L. R., Mistretta, S., Reaume, A. G., Greenberg, B. D., Siman, R., and Scott, R. W. (1998) J. Neurosci. 18, 1743-1752
7. Dovey, H. F., John, V., Anderson, J. P., Chen, L. Z., de Saint Andrieu, P., Fang, L. Y., Freedman, S. B., Folmer, B., Goldbach, E., Holsztynska, E. J., Hu, K. L., Johnson-Wood, K. L., Kennedy, S. L., Kholodenko, D., Knops, J. E., Latimer, L. H., Lee, M., Liao, Z., Lieberburg, I. M., Motter, R. N., Mutter, L. C., Nietz, J., Quinn, K. P., Sacchi, K. L., Seubert, P. A., Shopp, G. M., Thorsett, E. D., Tung, J. S., Wu, J., Yang, S., Yin, C. T., Schenk, D. B., May, P. C., Altstiel, L. D., Bender, M. H., Boggs, L. N., Britton, T. C., Clemens, J. C., Czilli, D. L., Dieckman-McGinty, D. K., Droste, J. J., Fuson, K. S., Gitter, B. D., Hyslop, P. A., Johnstone, E. M., Li, W. Y., Little, S. P., Mabry, T. E., Miller, F. D., and Audia, J. E. (2001) J. Neurochem. 76, 173-181
8. Bennett, R. G., Duckworth, W. C., and Hamel, F. G. (2000) J. Biol. Chem. 275, 36621-36625
9. Kurochkin, I. V. (2001) Trends Biochem. Sci. 26, 421-425
10. Qiu, W. Q., Walsh, D. M., Ye, Z., Vekrellis, K., Zhang, J., Podlisny, M. B., Rosner, M. R., Safavi, A., Hersh, L. B., and Selkoe, D. J. (1998) J. Biol. Chem. 273, 32730-32738
11. Vekrellis, K., Ye, Z., Qiu, W. Q., Walsh, D., Hartley, D., Chesneau, V., Rosner, M. R., and Selkoe, D. J. (2000) J. Neurosci. 20, 1657-1665
12. Leissring, M. A., Farris, W., Wu, X., Christodoulou, D. C., Haigis, M. C., Guarente, L., and Selkoe, D. J. (2004) Biochem. J. 383, 439-446
13. Farris, W., Mansourian, S., Chang, Y., Lindsley, L., Eckman, E. A., Frosch, M. P., Eckman, C. B., Tanzi, R. E., Selkoe, D. J., and Guenette, S. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 4162-4167
14. Miller, B. C., Eckman, E. A., Sambamurti, K., Dobbs, N., Chow, K. M., Eckman, C. B., Hersh, L. B., and Thiele, D. L. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 6221-6226
15. Leissring, M. A., Farris, W., Chang, A. Y., Walsh, D. M., Wu, X., Sun, X., Frosch, M. P., and Selkoe, D. J. (2003) Neuron 40, 1087-1093
16. Farris, W., Mansourian, S., Leissring, M. A., Eckman, E. A., Bertram, L., Eckman, C. B., Tanzi, R. E., and Selkoe, D. J. (2004) Am. J. Pathol. 164, 1425-1434
17. Bertram, L., Blacker, D., Mullin, K., Keeney, D., Jones, J., Basu, S., Yhu, S., McInnis, M. G., Go, R. C., Vekrellis, K., Selkoe, D. J., Saunders, A. J., and Tanzi, R. E. (2000) Science 290, 2302-2303
18. Edland, S. D., Wavrant-De Vriese, F., Compton, D., Smith, G. E., Ivnik, R., Boeve, B. F., Tangalos, E. G., and Petersen, R. C. (2003) Neurosci. Lett. 345, 21-24
19. Prince, J. A., Feuk, L., Gu, H. F., Johansson, B., Gatz, M., Blennow, K., and Brookes, A. J. (2003) Hum. Mutat. 22, 363-371
20. Blomqvist, M. E., Silburn, P. A., Buchanan, D. D., Andreasen, N., Blennow, K., Pedersen, N. L., Brookes, A. J., Mellick, G. D., and Prince, J. A. (2004) Neurogenetics 5, 115-119
21. Bertram, L., McQueen, M. B., Mullin, K., Blacker, D., and Tanzi, R. E. (2007) Nat. Genet. 39, 17-23
22. Blacker, D., Bertram, L., Saunders, A. J., Moscarillo, T. J., Albert, M. S., Wiener, H., Perry, R. T., Collins, J. S., Harrell, L. E., Go, R. C., Mahoney, A., Beaty, T., Fallin, M. D., Avramopoulos, D., Chase, G. A., Folstein, M. F., McInnis, M. G., Bassett, S. S., Doheny, K. J., Pugh, E. W., and Tanzi, R. E. (2003) Hum. Mol. Genet. 12, 23-32
23. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., and Stadlan, E. M. (1984) Neurology 34, 939-944
24. Mirra, S. S., Heyman, A., McKeel, D., Sumi, S. M., Crain, B. J., Brownlee, L. M., Vogel, F. S., Hughes, J. P., van Belle, G., and Berg, L. (1991) Neurology 41, 479-486
25. Hyman, B. T., and Trojanowski, J. Q. (1997) J. Neuropathol. Exp. Neurol. 56, 1095-1097
26. Huang, J., Guan, H., Booze, R. M., Eckman, C. B., and Hersh, L. B. (2004) Neurosci. Lett. 367, 85-87
27. Song, E. S., Juliano, M. A., Juliano, L., Fried, M. G., Wagner, S. L., and Hersh, L. B. (2004) J. Biol. Chem. 279, 54216-54220
28. Leissring, M. A., Lu, A., Condron, M. M., Teplow, D. B., Stein, R. L., Farris, W., and Selkoe, D. J. (2003) J. Biol. Chem. 278, 37314-37320
29. Ingelsson, M., Ramasamy, K., Cantuti-Castelvetri, I., Skoglund, L., Matsui, T., Orne, J., Kowa, H., Raju, S., Vanderburg, C. R., Augustinack, J. C., de Silva, R., Lees, A. J., Lannfelt, L., Growdon, J. H., Frosch, M. P., Standaert, D. G., Irizarry, M. C., and Hyman, B. T. (2006) Acta Neuropathol. (Berl.)
30. Baumeister, H., Muller, D., Rehbein, M., and Richter, D. (1993) FEBS Lett. 317, 250-254
31. Farris, W., Leissring, M. A., Hemming, M. L., Chang, A. Y., and Selkoe, D. J. (2005) Biochemistry 44, 6513-6525
32. Duckworth, W. C. (1988) Endocr. Rev. 9, 319-345
33. Saric, T., Muller, D., Seitz, H. J., and Pavelic, K. (2003) Mol. Cell. Endocrinol. 204, 11-20
34. Ogawa, W., Shii, K., Yonezawa, K., Baba, S., and Yokono, K. (1992) J. Biol. Chem. 267, 1310-1316
35. Bernstein, H. G., Ansorge, S., Riederer, P., Reiser, M., Frolich, L., and Bogerts, B. (1999) Neurosci. Lett. 263, 161-164
36. Ii, K., Ito, H., Tanaka, K., and Hirano, A. (1997) J. Neuropathol. Exp. Neurol. 56, 125-131
37. Perry, G., Friedman, R., Shaw, G., and Chau, V. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 3033-3036
38. Lowe, J., Mayer, R. J., and Landon, M. (1993) Brain Pathol. 3, 55-65
39. Song, E. S., Juliano, M. A., Juliano, L., and Hersh, L. B. (2003) J. Biol. Chem. 278, 49789-49794
40. Song, E. S., and Hersh, L. B. (2005) J. Mol. Neurosci. 25, 201-206
41. Udrisar, D. P., and Wanderley, M. I. (1992) Acta Physiol. Pharmacol. Ther. Latinoam. 42, 183-196
42. Hamel, F. G., Upward, J. L., and Bennett, R. G. (2003) Endocrinology 144, 2404-2408
43. Perez, A., Morelli, L., Cresto, J. C., and Castano, E. M. (2000) Neurochem. Res. 25, 247-255
44. Morelli, L., Llovera, R. E., Mathov, I., Lue, L. F., Frangione, B., Ghiso, J., and Castano, E. M. (2004) J. Biol. Chem. 279, 56004-56013
45. Cook, D. G., Leverenz, J. B., McMillan, P. J., Kulstad, J. J., Ericksen, S., Roth, R. A., Schellenberg, G. D., Jin, L. W., Kovacina, K. S., and Craft, S. (2003) Am. J. Pathol. 162, 313-319
46. Gutala, R. V., and Reddy, P. H. (2004) J. Neurosci. Methods 132, 101-107
47. Caccamo, A., Oddo, S., Sugarman, M. C., Akbari, Y., and LaFerla, F. M. (2005) Neurobiol. Aging 26, 645-654