Design, evaluation and structure-Activity relationship studies of the AChE reactivators against organophosphorus pesticides

Medicinal Research Reviews

Volumn 31, Issue 4, 2011, Pages 548-575

  Musilek, Kamil ^a,b   Dolezal, Martin ^c   Gunn Moore, Frank ^d   Kuca, Kamil ^b,e  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b J E PURKINJE UNIVERSITY   (Czech Republic)

^c Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^d UNIVERSITY OF ST ANDREWS   (United Kingdom)

^e UNIVERSITY OF DEFENCE   (Czech Republic)

Author keywords

Acetylcholinesterase; Insecticide; Oxime; Pesticide; Reactivation; SAR

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ATROPINE; CHLORPYRIFOS; CHOLINESTERASE; CHOLINESTERASE REACTIVATOR; DIAZEPAM; DIMPYLATE; OBIDOXIME; PARAOXON; PRALIDOXIME; SARIN; SOMAN; TABUN; TRIMEDOXIME;

ARTICLE; BLOOD BRAIN BARRIER; DRUG DESIGN; DRUG INTOXICATION; DRUG SCREENING; ERYTHROCYTE; HUMAN; INDUSTRIALIZATION; INTOXICATION; NONHUMAN; SOCIAL ASPECT; STRUCTURE ACTIVITY RELATION; SUICIDE;

ACETYLCHOLINESTERASE; ANIMALS; CHOLINESTERASE REACTIVATORS; DRUG DESIGN; HUMANS; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79959561233     PISSN: 01986325     EISSN: 10981128     Source Type: Journal    
DOI: 10.1002/med.20192     Document Type: Article

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