Efficacy of eight experimental bispyridinium oximes against paraoxon-induced mortality: Comparison with the conventional oximes pralidoxime and obidoxime

Neurotoxicity Research

Volumn 16, Issue 1, 2009, Pages 60-67

  Nurulain, S M ^a   Lorke, D E ^a,b   Hasan, M Y ^a   Shafiullah, M ^a   Kuca K ^c   Musilek, K ^c   Petroianu, Georg A ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNIVERSITY OF HAMBURG   (Germany)

^c UNIVERSITY OF DEFENCE   (Czech Republic)

Author keywords

Aldoxime; Cox analysis; K oxime; Organophosphate; Paraoxon; Rat

Indexed keywords

BIS(PYRIDINIUM OXIME) DERIVATIVE; K 107; K 108; K 113; K 27; K 48; K 53; K 74; K 75; OBIDOXIME; ORGANONITROGEN DERIVATIVE; OXIME; PARAOXON; PRALIDOXIME; PYRIDINE DERIVATIVE; PYRIDINIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IN VIVO STUDY; INTOXICATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME;

ANIMALS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; DOSE-RESPONSE RELATIONSHIP, DRUG; LETHAL DOSE 50; MALE; OBIDOXIME CHLORIDE; PARAOXON; PRALIDOXIME COMPOUNDS; PROPORTIONAL HAZARDS MODELS; RATS; RATS, WISTAR; SURVIVAL ANALYSIS; TIME FACTORS;

RATTUS;

EID: 70349733145     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12640-009-9048-7     Document Type: Article

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