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Volumn 32, Issue 2, 2009, Pages 128-138

A comparison of neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats

Author keywords

Atropine; Functional observational battery; HI 6; K oximes; Obidoxime; Rats; Tabun

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ATROPINE; K 203; OBIDOXIME; OXIME DERIVATIVE; TABUN; TIPINDOLE METHIODIDE; UNCLASSIFIED DRUG;

EID: 71049150798     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.1080/01480540802593873     Document Type: Article
Times cited : (17)

References (27)
  • 1
    • 0043265155 scopus 로고    scopus 로고
    • Tabun-reappearance 50 years later
    • (in Czech)
    • Cabal J, Bajgar J. (1999). Tabun-reappearance 50 years later (in Czech). Chem Listy 93:27-31.
    • (1999) Chem Listy , vol.93 , pp. 27-31
    • Cabal, J.1    Bajgar, J.2
  • 2
    • 4744354029 scopus 로고    scopus 로고
    • Specification of the structure of oximes able to reactivate tabun-inhibited acetylcholinesterase
    • Cabal J, Kuca K, Kassa J. (2004). Specification of the structure of oximes able to reactivate tabun-inhibited acetylcholinesterase. Pharmacol Toxicol 95:81-86.
    • (2004) Pharmacol Toxicol , vol.95 , pp. 81-86
    • Cabal, J.1    Kuca, K.2    Kassa, J.3
  • 3
    • 0030834139 scopus 로고    scopus 로고
    • Pharmacokinetics and effects of HI-6 in blood and brain of soman-intoxicated rats: A microdialysis study
    • Cassel G, Karlsson L, Waara L, Ang Wee K, Goransson-Nyberg A. (1997). Pharmacokinetics and effects of HI-6 in blood and brain of soman-intoxicated rats: A microdialysis study. Eur J Pharmacol 332:43-52.
    • (1997) Eur J Pharmacol , vol.332 , pp. 43-52
    • Cassel, G.1    Karlsson, L.2    Waara, L.3    Ang Wee, K.4    Goransson-Nyberg, A.5
  • 4
    • 0028132872 scopus 로고
    • Review of oximes available for treatment of nerve agent poisoning
    • Dawson RM. (1994). Review of oximes available for treatment of nerve agent poisoning. J Appl Toxicol 14:317-331.
    • (1994) J Appl Toxicol , vol.14 , pp. 317-331
    • Dawson, R.M.1
  • 5
    • 27444441472 scopus 로고    scopus 로고
    • Prediction of a new broad-spectrum reactivator capable of reactivating acetylcholinesterase inhibited by nerve agents
    • Dohnal V, Kuca K, Jun D. (2005). Prediction of a new broad-spectrum reactivator capable of reactivating acetylcholinesterase inhibited by nerve agents. J Appl Toxicol 3:139-145.
    • (2005) J Appl Toxicol , vol.3 , pp. 139-145
    • Dohnal, V.1    Kuca, K.2    Jun, D.3
  • 6
    • 30144445702 scopus 로고    scopus 로고
    • Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase
    • Ekström F, Akfur C, Tunemalm AK, Lundberg S. (2006). Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase. Biochemistry 45:74-81.
    • (2006) Biochemistry , vol.45 , pp. 74-81
    • Ekström, F.1    Akfur, C.2    Tunemalm, A.K.3    Lundberg, S.4
  • 7
    • 0002196641 scopus 로고
    • Clustering of neurobehavioral measures of toxicity
    • Frantik E, Hornychova M. (1995). Clustering of neurobehavioral measures of toxicity. Homeostasis 36:19-25.
    • (1995) Homeostasis , vol.36 , pp. 19-25
    • Frantik, E.1    Hornychova, M.2
  • 9
    • 0027655984 scopus 로고
    • Anticholinesterase activity and delayed neurotoxic effects of tabun in hens
    • Jokanovic M. (1993). Anticholinesterase activity and delayed neurotoxic effects of tabun in hens. Vojvosanit Pregl 50:451-456.
    • (1993) Vojvosanit Pregl , vol.50 , pp. 451-456
    • Jokanovic, M.1
  • 10
    • 0029874674 scopus 로고    scopus 로고
    • Oxime-induced reactivation of acetylcholinesterese inhibited by phosphoramidates
    • Jokanovic M, Maksimovic M, Kilibarda V, Jovanovic D, Savic D. (1996). Oxime-induced reactivation of acetylcholinesterese inhibited by phosphoramidates. Toxicol Lett 85:35-39.
    • (1996) Toxicol Lett , vol.85 , pp. 35-39
    • Jokanovic, M.1    Maksimovic, M.2    Kilibarda, V.3    Jovanovic, D.4    Savic, D.5
  • 11
    • 0036447187 scopus 로고    scopus 로고
    • Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents
    • Kassa J. (2002). Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents. J Toxicol Clin Toxicol 40:803-816.
    • (2002) J Toxicol Clin Toxicol , vol.40 , pp. 803-816
    • Kassa, J.1
  • 12
    • 0033037801 scopus 로고    scopus 로고
    • A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with currently available oximes and H oximes against soman by in vitro and in vivo methods
    • DOI 10.1016/S0300-483X(98)00146-2, PII S0300483X98001462
    • Kassa J, Cabal J. (1999a). A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with currently available oximes and H oximes against soman by in vitro and in vivo methods. Toxicology 132:111-118. (Pubitemid 29121949)
    • (1999) Toxicology , vol.132 , Issue.2-3 , pp. 111-118
    • Kassa, J.1    Cabal, J.2
  • 13
    • 0032929883 scopus 로고    scopus 로고
    • A comparison of the efficacy of acetylcholinesterase reactivators against cyclohexyl methylphosphonofluoridate (GF agent) by in vitro and in vivo methods
    • Kassa J, Cabal J. (1999b). A comparison of the efficacy of acetylcholinesterase reactivators against cyclohexyl methylphosphonofluoridate (GF agent) by in vitro and in vivo methods. Pharmacol Toxicol 84:41-45. (Pubitemid 29069238)
    • (1999) Pharmacology and Toxicology , vol.84 , Issue.1 , pp. 41-45
    • Kassa, J.1    Cabal, J.2
  • 14
    • 33751324312 scopus 로고    scopus 로고
    • A comparison of the efficacy of currently available oximes against tabun in rats
    • Kassa J, Cabal J, Kuca K. (2005). A comparison of the efficacy of currently available oximes against tabun in rats. Biologia 60(Suppl 17):77-79.
    • (2005) Biologia , vol.60 , Issue.SUPPL. 17 , pp. 77-79
    • Kassa, J.1    Cabal, J.2    Kuca, K.3
  • 15
    • 37149011244 scopus 로고    scopus 로고
    • An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice
    • DOI 10.1016/j.tox.2007.10.015, PII S0300483X07007457
    • Kassa J, Karasova J, Musilek K, Kuca K. (2008a). An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) with commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice. Toxicology 243:311-316. (Pubitemid 350256870)
    • (2008) Toxicology , vol.243 , Issue.3 , pp. 311-316
    • Kassa, J.1    Karasova, J.2    Musilek, K.3    Kuca, K.4
  • 16
    • 56449111425 scopus 로고    scopus 로고
    • A comparison of the therapeutic and reactivating efficacy of newly developed bispyridinium oximes (K206, K269) with currently available oximes against tabun in rats and mice
    • Kassa J, Karasova J, Bajgar J, Kuca K, Musilek K. (2008b). A comparison of the therapeutic and reactivating efficacy of newly developed bispyridinium oximes (K206, K269) with currently available oximes against tabun in rats and mice. J Enz Inhib Med Chem 23:776-780.
    • (2008) J Enz Inhib Med Chem , vol.23 , pp. 776-780
    • Kassa, J.1    Karasova, J.2    Bajgar, J.3    Kuca, K.4    Musilek, K.5
  • 17
    • 0038378860 scopus 로고    scopus 로고
    • Neuroprotective effects of currently used antidotes in tabun-poisoned rats
    • Kassa J, Krejcova G. (2003). Neuroprotective effects of currently used antidotes in tabun-poisoned rats. Pharmacol Toxicol. 92:258-264.
    • (2003) Pharmacol Toxicol. , vol.92 , pp. 258-264
    • Kassa, J.1    Krejcova, G.2
  • 18
    • 33847239864 scopus 로고    scopus 로고
    • The development of new structural analogues of oximes for the antidotal treatment of poisoning by nerve agents and the comparison of their reactivating and therapeutic efficacy with currently available oximes
    • Kassa J, Kuca K, Bartosova L, Kunesova G. (2007). The development of new structural analogues of oximes for the antidotal treatment of poisoning by nerve agents and the comparison of their reactivating and therapeutic efficacy with currently available oximes. Curr Org Chem 11:267-283.
    • (2007) Curr Org Chem , vol.11 , pp. 267-283
    • Kassa, J.1    Kuca, K.2    Bartosova, L.3    Kunesova, G.4
  • 19
    • 0037424754 scopus 로고    scopus 로고
    • Synthesis of a potential reactivator of acetylcholinesterase1-(4- hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium)-propane dibromide
    • Kuca K, Bielavsky J, Cabal J, Bielavska M. (2003a). Synthesis of a potential reactivator of acetylcholinesterase1-(4-hydroxyiminomethylpyridinium)- 3-(carbamoylpyridinium)-propane dibromide. Tetrahedron Lett 44:3123-3125.
    • (2003) Tetrahedron Lett , vol.44 , pp. 3123-3125
    • Kuca, K.1    Bielavsky, J.2    Cabal, J.3    Bielavska, M.4
  • 20
    • 17444446525 scopus 로고    scopus 로고
    • Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase
    • Kuca K, Bielavsky J, Cabal J, Kassa J. (2003b). Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase. Bioorg Med Chem Lett 13:3545-3547.
    • (2003) Bioorg Med Chem Lett , vol.13 , pp. 3545-3547
    • Kuca, K.1    Bielavsky, J.2    Cabal, J.3    Kassa, J.4
  • 21
    • 33646056667 scopus 로고    scopus 로고
    • Structural requirements of acetylcholinesterase reactivators
    • Kuca K, Jun D, Musilek K. (2006). Structural requirements of acetylcholinesterase reactivators. Mini Rev Med Chem 6:269-277.
    • (2006) Mini Rev Med Chem , vol.6 , pp. 269-277
    • Kuca, K.1    Jun, D.2    Musilek, K.3
  • 22
    • 0027281533 scopus 로고
    • Organophosphate poisoning
    • Marrs TC. (1993). Organophosphate poisoning. Pharmacol Ther 58:51-66.
    • (1993) Pharmacol Ther , vol.58 , pp. 51-66
    • Marrs, T.C.1
  • 24
    • 39349101032 scopus 로고    scopus 로고
    • Synthesis of mono-oxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun-and paraoxon-inhibited acetylcholinesterase
    • Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M. (2008). Synthesis of mono-oxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun-and paraoxon-inhibited acetylcholinesterase. J Enz Inhib Med Chem 23:70-76.
    • (2008) J Enz Inhib Med Chem , vol.23 , pp. 70-76
    • Musilek, K.1    Holas, O.2    Kuca, K.3    Jun, D.4    Dohnal, V.5    Opletalova, V.6    Dolezal, M.7
  • 25
    • 0022553280 scopus 로고
    • Reactivation of nerve agent-inhibited acetylcholinesterase by HI-6 and obidoxime
    • Puu G, Artursson E, Bucht G. (1986). Reactivation of nerve agent-inhibited acetylcholinesterase by HI-6 and obidoxime. Biochem Pharmacol 35:1505-1510.
    • (1986) Biochem Pharmacol , vol.35 , pp. 1505-1510
    • Puu, G.1    Artursson, E.2    Bucht, G.3
  • 27
    • 0031978963 scopus 로고    scopus 로고
    • Reactivating potency of obidoxime, pralidoxime, HI-6, and HLö-7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds
    • Worek F, Widmann R, Knopff O, Szinicz L. (1998). Reactivating potency of obidoxime, pralidoxime, HI-6, and HLö-7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds. Arch Toxicol 72:237-243.
    • (1998) Arch Toxicol , vol.72 , pp. 237-243
    • Worek, F.1    Widmann, R.2    Knopff, O.3    Szinicz, L.4


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