Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro

Journal of Applied Toxicology

Volumn 27, Issue 6, 2007, Pages 582-588

  Worek, F ^a   Aurbek, N ^a   Thiermann, H ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

Author keywords

Acetylcholinesterase; HI 6; Human; Obidoxime; Organophosphate; Reactivation

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; CHOLINESTERASE REACTIVATOR; CYCLOSARIN; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; OBIDOXIME; ORGANOPHOSPHATE; OXIME; PARAOXON; PESTICIDE; SARIN; TABUN;

ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME INACTIVATION; FEASIBILITY STUDY; HEALTH HAZARD; HUMAN; PRIORITY JOURNAL;

ACETYLCHOLINESTERASE; ANTIDOTES; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; ERYTHROCYTE MEMBRANE; FEASIBILITY STUDIES; HUMANS; OBIDOXIME CHLORIDE; ORGANOPHOSPHORUS COMPOUNDS; ORGANOTHIOPHOSPHORUS COMPOUNDS; PARAOXON; PHOSPHORIC ACID ESTERS; PYRIDINIUM COMPOUNDS; SARIN; TIME FACTORS;

EID: 36148961940     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1241     Document Type: Article

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