Lessons to be learnt from organophosphorus pesticide poisoning for the treatment of nerve agent poisoning

Toxicology

Volumn 233, Issue 1-3 SPEC. ISS., 2007, Pages 145-154

  Thiermann, H ^a   Szinicz, L ^a   Eyer, P ^b   Felgenhauer, N ^c   Zilker, T ^c   Worek, F ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Human; Nerve agents; Neuromuscular transmission; Organophosphorus compounds; Oximes; Therapy

Indexed keywords

ACETYLCHOLINESTERASE; ANTIDOTE; ATROPINE; CYCLOSARIN; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; NERVE GAS; OBIDOXIME; ORGANOPHOSPHATE PESTICIDE; OXIME; PARAOXON; S [2 (DIETHYLAMINO)ISOBUTYL]METHYLPHOSPHONOTHIOATE; SARIN; SOMAN; UNCLASSIFIED DRUG;

ARTICLE; ARTIFICIAL VENTILATION; CONTINUOUS INFUSION; DISEASE COURSE; DRUG EFFICACY; ENZYME ACTIVITY; ERYTHROCYTE; HUMAN; INHALATION; INTOXICATION; LOW DRUG DOSE; MONITORING; NEUROMUSCULAR TRANSMISSION; PRIORITY JOURNAL; SYMPTOMATOLOGY; TERRORISM; TREATMENT DURATION;

ANIMALS; CHEMICAL WARFARE AGENTS; CHOLINESTERASE REACTIVATORS; CHOLINESTERASES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOLECULAR STRUCTURE; NEUROTOXICITY SYNDROMES; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33947632055     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.11.056     Document Type: Article

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