Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon

Toxicological Sciences

Volumn 77, Issue 2, 2004, Pages 258-262

  Petrikovics, I ^a   Papahadjopoulos, D ^b   Hong, K ^b   Cheng, T C ^a   Baskin, Steven I ^a   Jiang, J ^c   Jaszberenyi, J C ^d   Logue, B A ^a   Szilasi, M ^e   McGuinn, W D ^c   Way, J L ^c  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^d TEXAS A M COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Long circulating liposomes; OPA anhydrase; Organophorus antagonism; Ortanophosphorus hydrolase (OPH); Paraoxon antagonism; Paraoxonase; Prophylactic; Steath liposomes; Sterically stabilized liposomes; Therapeutic

Indexed keywords

ANTIDOTE; ATROPINE; CHOLINESTERASE INHIBITOR; LIPOSOME; OXYGENASE; PARAOXON; PRALIDOXIME; RECOMBINANT ENZYME;

ANIMAL EXPERIMENT; ARTICLE; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; DETOXIFICATION; DRUG EFFICACY; DRUG POTENCY; ENCAPSULATION; ENZYME ACTIVITY; INTOXICATION; LETHAL DOSE; MALE; MOUSE; NEUROTOXICITY; NONHUMAN;

ANIMALS; ANTIDOTES; ARYLDIALKYLPHOSPHATASE; ATROPINE; CHOLINESTERASE REACTIVATORS; DRUG COMBINATIONS; INSECTICIDES; LETHAL DOSE 50; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; MUSCARINIC ANTAGONISTS; NEUROTOXICITY SYNDROMES; PARAOXON; PRALIDOXIME COMPOUNDS;

EID: 10744220982     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg185     Document Type: Article

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